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International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056
Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072
© 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 1491
SALIENCY BASED HOOKWORM AND INFECTION DETECTION FOR
WIRELESS CAPSULE ENDOSCOPY DIAGNOSIS
S. Haritha1, N. Nivetha2, G. Radhika3, V. Jeyaramya4
1Student, Department of Electronics and Communication, Panimalar Institute of Technology, Chennai, Tamil Nadu
2 Student, Department of Electronics and Communication, Panimalar Institute of Technology, Chennai, Tamil Nadu
3 Student, Department of Electronics and Communication, Panimalar Institute of Technology, Chennai, Tamil Nadu
4Assistant Professor, Department of Electronics and Communication, Panimalar Institute of Technology, Chennai,
Tamil Nadu
---------------------------------------------------------------------***---------------------------------------------------------------------
Abstract - An ulcer is a discontinuity or breaks in a bodily
membrane that impedes the organ of which that membrane is
a part of continuing its normal functions. Wireless capsule
endoscopy (WCE) is a radical, patient-friendlyimagingsystem
that aids non-invasive photographic review of the patient’s
digestive tract and, especially, small intestine. However,
reviewing the endoscopic dataistime-consumingandrequires
the intense labor of highly experiencedphysicians. Inproposed
method, a novel multi-level super pixel based image
segmentation is used. After that, a particle swarm
optimization using color and texture based features are
extracted to diagnosis the disease.
Key Words: WCE (Wireless Capsule Endoscopy),
Endoscopic, Super-Pixel, Segmentation,PSO(ParticleSwarm
Optimization)
1.INTRODUCTION
Peptic ulcer disease (PUD),alsoidentifiedasa pepticulcer
or stomach ulcer, is a chink in the stomach, first part of the
small intestine, or sometimes the lower esophagus. The
most common symptoms are waking from sleep with upper
abdominal pain that can be reduced by eating. The ache is
often explained as a burning or dull ache. Other symptoms
include belching, vomiting, weight loss or poor appetite.
About a third of older people have no symptoms.
Complications may include bleeding, perforation and
blockage of the stomach. Bleeding occurs in asmanyas15%
of people.
Identification and treatment will depend on your
symptoms and the sternness of your ulcer. To diagnose a
stomach ulcer, the doctor will check the medical history
along with the symptoms and any prescription or over-the-
counter medications taken. In a breath test, you’ll be
instructed to drink a clear liquid and breathe into a bag,
which is then sealed. Tests and procedure used to diagnose
stomach ulcers also include:
 Barium X-Ray
 Endoscopy
 Endoscopy biopsy
1.1 HOOKWORM
Hookworms are parasites that affect your lungs and
small intestine. Humans contract hookworms through
roundworm eggs and larvae found in dirt contaminated by
faeces. The larvae enter your skin, travel through your
bloodstream, and enter your lungs. Theyalsotravel through
your windpipe and are carried to your small intestine when
you swallow.
SYMPTOMS:
 Abdominal pain
 Intestinal cramps
 Nausea
 Fever
 Blood in your stool
Fig: Hookworm
2. METHODOLOGY
Endoscopy constitutes the most common approach for
diagnosing gastrointestinal (GI) tract related diseases.
Traditional endoscopy techniques play an important role to
the examination of the upper and lower ends of the GI tract.
However, these techniques, apart from being highly
inconvenient for the patients, can hardlyreachthemainpart
of GI, the small bowel, due to its 7m-length and numerous
windings. The solution to this limitation is the recently
established WCE. WCE has markeda revolutioninthefieldof
GI imaging, beginning an era of non-invasive visualization of
the GI tract and, especially, the entire small bowel.Oneofthe
most common GI medical findings efficiently detected by
WCE is an ulcer. Approximately 10% of the people suffer
from ulcerations. The main disadvantage of WCEisthetime-
consuming task of reviewing the 55.000 images produced.
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056
Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072
© 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 1492
The analysis of this video data costs 1-2 h of intense labour
for an experienced physician. Besides, abnormalitiesmay be
easily missed due to oversight since they may appearinonly
one or two frames. The techniques proposed includetexture
spectrum along with neural networks and non-negative
matrix factorization. Texture and colour features extracted
from various colour spaces have contributed to ulcer
recognition. At last, the texture analysis output is classified
into healthy and ulcerous with the aid of various
classification algorithms.
2.1 PRE-PROCESSING
Preprocessing algorithms are the first processing step
after capturing the image, as we see inmanyoftheexamples.
The preprocessing functions discussed here can be divided
into two basic groups, reliant on what the resulting
brightness value of a pixel in the yield image isderivedfrom:
1. Pixel operations compute the brightnessofa pixel inthe
output image exclusively from the intensity of the matching
pixel in the source image. This group also encompasses
image arithmetic functions which combine several images.
Pixel operations can be further divided into homogeneous
and in homogeneous pixel operations.Homogeneousactions
use the same transformation function for each pixel, for in
homogeneous ones the transformation function dependson
the position of the pixel in the image. Pixel operations are
discussed in the subsequent sections:
 Grayscale transformations
 Image arithmetic
2. Local operations take a certain neighborhood of the
present pixel into account whencalculatingthebrightnessof
the corresponding output image pixel.
Local operations are discussed in the following sections:
 Linear filters
 Median filter
 Morphological filter
 Other non-linear filters
2.3 FEATURE SELECTION
Feature selection is the process of picking a subset of the
original featurespacesaccordingtodiscriminationcapability
to improve the quality of data. This paper proposes a
suggested image recovery model based on extracting the
most applicable features from the whole features according
to a feature selection technique. Feature extraction is done
using the Gray level co-occurrence matrix(GLCM). It checks
the repetition of the abnormal gray levels using a trained
database as a reference. It can not only achieve maximum
recognition rate but can also simplify the calculation of the
image retrieval process. Particle Swarm Optimization (PSO)
is used for feature selection technique. PSO is a
computational method that optimizes a problem by
iteratively trying to improve a candidate solution with
certain parameters like;
 Energy
 Contrast
 Correlation
 Homogeneity etc.,
2.4 PARTICLE SWARM OPTIMIZATION
Particle swarm optimization (PSO) is a computational
method that heightens a delinquent by iteratively trying to
improve a candidate solution withregardtoa givenmeasure
of quality. PSO is a metaheuristic as it makes few or no
norms about the tricky being enhanced and can search very
great spaces of candidate solutions. PSO can also be used on
optimization problems that are partially irregular, noisy,
change over time, etc.
2.5 BLOCK DIAGRAM
The proposed block diagram for this project is given as
follows:
Fig: Block Diagram
2.5.1 INPUT IMAGE
Input images should be in *.jpg; or the *.png format the
images used for this project were taken from the related
websites.
.
Fig: Sample WCE images
INPUT PREPROCESSING THRESHOLD
SEGMENTATION
EDGE DETECTION
MULTI LEVEL SUPER
PIXEL
DATA BASE
PSO OUTPUT
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056
Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072
© 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 1493
2.6 ALGORITHM
A basic optional of the PSO algorithm works by having a
people (called a swarm) of entrant solutions (called
particles). These particles are moved around in the search
space according to a few simple formulate. The movements
of the particles are guided by their own best-knownposition
in the search space as well as the entireswarm'sbest-known
position. When improved, sites are being discovered these
will then come to chaperon the schedules of the swarm. The
process is repeated and by doing so it is hoped, but not
guaranteed, that a satisfactory solution will eventually be
discovered.
Officially, let f: Rn → R be the charge function which must
be minimalized. The function takes a candidate solution as
an argument in the form of a vector of real numbers and
produces a real number as yield which indicates the
objective function value of the given applicant solution. The
gradient off is not known. The goal is to find a solution a for
which f(a) ≤ f(b) for all b in the search-space, which would
mean a is the universal minimum.Maximizationcanbemade
by considering the function h = -f instead.
Let S be the number of particles in the swarm,eachhaving
a position xi ∈ Rn in the search space and a swiftnessvi ∈Rn.
Let pi be the best-known position of particleiandletg bethe
best-known position of the entire swarm. A basic PSO
algorithm is then:
For each particle i = 1, ..., S do:
Initialize the particle's location with a uniformly
distributed random vector: xi ~ U(blo, bup), where blo and bup
are the lower and upper boundaries of the search-space.
Set the particle's best known position to its primary
position: pi ← xi
If (f(pi) < f(g)) update theswarm'sbestknownposition:
g ← pi
Initialize the particle's velocity: vi ~ U(-|bup-blo|, |bup-
blo|)
Until a expiry criterion is met (e.g. number of iterations
performed, or a solution with adequate objective function
value is found), repeat:
For each particle i = 1, ..., S do:
For each dimension d = 1, ..., n do:
Élite random numbers: rp, rg ~ U(0,1)
Update the particle's velocity: vi,d← ωvi,d+φprp
(pi,d-xi,d) + φg rg (gd-xi,d)
Keep posted the particle's position: xi ← xi + vi
If (f(xi) < f(pi)) do:
Apprise the particle's best known position: pi ←xi
If (f(pi) < f(g)) update the swarm's best known
position: g ← pi
Now g holds the best-found result.
The parameters ω, φp, and φg are selected bytheexpertand
control the behavior and efficacy of the PSO method.
2.7 MEDIAN FILTER
A median filter is used to preserve edges while
eliminating random clatters present in the image. For a two-
dimensional image, the pictures are of 3-by-3 neighborhood
value. The median filter swaps each entrywiththemedianof
the neighboring entries.
2.8 SEGMENTATION
Image segmentation is the process of partitioning a
digital image into multiple segments
 THRESHOLDING
The simplest thresholding methods replace each pixel in
an image with a black pixel if the image intensity is fewer
than some static constant T or a white pixel if the image
intensity is greater than that constant. Here, instead ofusing
a local threshold value we use a formulated global threshold
value.
 EDGE SEGMENTATION
Image processing is any form of information processing
for which the input is an image, such as frames of video; the
output is not necessarily an image but can be a set of
features giving information about the image. Since images
contain lots of redundant data,scholarshavediscoveredthat
the most important information lies in its edges. Edges
typically correspond to points in the image where the gray
value changes significantly from one pixel to the next.
3 RESULT
3.1Analysis of a Normal or Healthy abdomen image:
(a) Input Image
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056
Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072
© 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 1494
(b) Pre-processed image
(c) Segmented image
(d) Classification (e) Optimized Image
(f) Output
3.2 Analysis of abnormal or infected abdomen image:
(a) Input Image
(b) Pre-processed image
(a) Segmented image
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056
Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072
© 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 1495
(d) Classification (e) Optimized Image
(f) Output
4.CONCLUSION
In this paper, we have detected the abnormalities in the
abdomen using the wireless capsule endoscopy (WCE)
images. The microscopic images of ulcer are examined by
changes based on texture, geometry, colour, statically
analysis used as the input. We have trainedandclassifiedthe
microscopic images. This system is reliable and cost-
effective.
ACKNOWLEDGMENT:
I sincerely thank my external guide and my internal guide
for all their help and guidance and my project coordinators
for giving me the opportunity to conduct my project work in
Panimalar Institute of Technology.
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Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072
© 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 1496
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Saliency Based Hookworm and Infection Detection for Wireless Capsule Endoscopy Diagnosis

  • 1. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056 Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072 © 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 1491 SALIENCY BASED HOOKWORM AND INFECTION DETECTION FOR WIRELESS CAPSULE ENDOSCOPY DIAGNOSIS S. Haritha1, N. Nivetha2, G. Radhika3, V. Jeyaramya4 1Student, Department of Electronics and Communication, Panimalar Institute of Technology, Chennai, Tamil Nadu 2 Student, Department of Electronics and Communication, Panimalar Institute of Technology, Chennai, Tamil Nadu 3 Student, Department of Electronics and Communication, Panimalar Institute of Technology, Chennai, Tamil Nadu 4Assistant Professor, Department of Electronics and Communication, Panimalar Institute of Technology, Chennai, Tamil Nadu ---------------------------------------------------------------------***--------------------------------------------------------------------- Abstract - An ulcer is a discontinuity or breaks in a bodily membrane that impedes the organ of which that membrane is a part of continuing its normal functions. Wireless capsule endoscopy (WCE) is a radical, patient-friendlyimagingsystem that aids non-invasive photographic review of the patient’s digestive tract and, especially, small intestine. However, reviewing the endoscopic dataistime-consumingandrequires the intense labor of highly experiencedphysicians. Inproposed method, a novel multi-level super pixel based image segmentation is used. After that, a particle swarm optimization using color and texture based features are extracted to diagnosis the disease. Key Words: WCE (Wireless Capsule Endoscopy), Endoscopic, Super-Pixel, Segmentation,PSO(ParticleSwarm Optimization) 1.INTRODUCTION Peptic ulcer disease (PUD),alsoidentifiedasa pepticulcer or stomach ulcer, is a chink in the stomach, first part of the small intestine, or sometimes the lower esophagus. The most common symptoms are waking from sleep with upper abdominal pain that can be reduced by eating. The ache is often explained as a burning or dull ache. Other symptoms include belching, vomiting, weight loss or poor appetite. About a third of older people have no symptoms. Complications may include bleeding, perforation and blockage of the stomach. Bleeding occurs in asmanyas15% of people. Identification and treatment will depend on your symptoms and the sternness of your ulcer. To diagnose a stomach ulcer, the doctor will check the medical history along with the symptoms and any prescription or over-the- counter medications taken. In a breath test, you’ll be instructed to drink a clear liquid and breathe into a bag, which is then sealed. Tests and procedure used to diagnose stomach ulcers also include:  Barium X-Ray  Endoscopy  Endoscopy biopsy 1.1 HOOKWORM Hookworms are parasites that affect your lungs and small intestine. Humans contract hookworms through roundworm eggs and larvae found in dirt contaminated by faeces. The larvae enter your skin, travel through your bloodstream, and enter your lungs. Theyalsotravel through your windpipe and are carried to your small intestine when you swallow. SYMPTOMS:  Abdominal pain  Intestinal cramps  Nausea  Fever  Blood in your stool Fig: Hookworm 2. METHODOLOGY Endoscopy constitutes the most common approach for diagnosing gastrointestinal (GI) tract related diseases. Traditional endoscopy techniques play an important role to the examination of the upper and lower ends of the GI tract. However, these techniques, apart from being highly inconvenient for the patients, can hardlyreachthemainpart of GI, the small bowel, due to its 7m-length and numerous windings. The solution to this limitation is the recently established WCE. WCE has markeda revolutioninthefieldof GI imaging, beginning an era of non-invasive visualization of the GI tract and, especially, the entire small bowel.Oneofthe most common GI medical findings efficiently detected by WCE is an ulcer. Approximately 10% of the people suffer from ulcerations. The main disadvantage of WCEisthetime- consuming task of reviewing the 55.000 images produced.
  • 2. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056 Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072 © 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 1492 The analysis of this video data costs 1-2 h of intense labour for an experienced physician. Besides, abnormalitiesmay be easily missed due to oversight since they may appearinonly one or two frames. The techniques proposed includetexture spectrum along with neural networks and non-negative matrix factorization. Texture and colour features extracted from various colour spaces have contributed to ulcer recognition. At last, the texture analysis output is classified into healthy and ulcerous with the aid of various classification algorithms. 2.1 PRE-PROCESSING Preprocessing algorithms are the first processing step after capturing the image, as we see inmanyoftheexamples. The preprocessing functions discussed here can be divided into two basic groups, reliant on what the resulting brightness value of a pixel in the yield image isderivedfrom: 1. Pixel operations compute the brightnessofa pixel inthe output image exclusively from the intensity of the matching pixel in the source image. This group also encompasses image arithmetic functions which combine several images. Pixel operations can be further divided into homogeneous and in homogeneous pixel operations.Homogeneousactions use the same transformation function for each pixel, for in homogeneous ones the transformation function dependson the position of the pixel in the image. Pixel operations are discussed in the subsequent sections:  Grayscale transformations  Image arithmetic 2. Local operations take a certain neighborhood of the present pixel into account whencalculatingthebrightnessof the corresponding output image pixel. Local operations are discussed in the following sections:  Linear filters  Median filter  Morphological filter  Other non-linear filters 2.3 FEATURE SELECTION Feature selection is the process of picking a subset of the original featurespacesaccordingtodiscriminationcapability to improve the quality of data. This paper proposes a suggested image recovery model based on extracting the most applicable features from the whole features according to a feature selection technique. Feature extraction is done using the Gray level co-occurrence matrix(GLCM). It checks the repetition of the abnormal gray levels using a trained database as a reference. It can not only achieve maximum recognition rate but can also simplify the calculation of the image retrieval process. Particle Swarm Optimization (PSO) is used for feature selection technique. PSO is a computational method that optimizes a problem by iteratively trying to improve a candidate solution with certain parameters like;  Energy  Contrast  Correlation  Homogeneity etc., 2.4 PARTICLE SWARM OPTIMIZATION Particle swarm optimization (PSO) is a computational method that heightens a delinquent by iteratively trying to improve a candidate solution withregardtoa givenmeasure of quality. PSO is a metaheuristic as it makes few or no norms about the tricky being enhanced and can search very great spaces of candidate solutions. PSO can also be used on optimization problems that are partially irregular, noisy, change over time, etc. 2.5 BLOCK DIAGRAM The proposed block diagram for this project is given as follows: Fig: Block Diagram 2.5.1 INPUT IMAGE Input images should be in *.jpg; or the *.png format the images used for this project were taken from the related websites. . Fig: Sample WCE images INPUT PREPROCESSING THRESHOLD SEGMENTATION EDGE DETECTION MULTI LEVEL SUPER PIXEL DATA BASE PSO OUTPUT
  • 3. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056 Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072 © 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 1493 2.6 ALGORITHM A basic optional of the PSO algorithm works by having a people (called a swarm) of entrant solutions (called particles). These particles are moved around in the search space according to a few simple formulate. The movements of the particles are guided by their own best-knownposition in the search space as well as the entireswarm'sbest-known position. When improved, sites are being discovered these will then come to chaperon the schedules of the swarm. The process is repeated and by doing so it is hoped, but not guaranteed, that a satisfactory solution will eventually be discovered. Officially, let f: Rn → R be the charge function which must be minimalized. The function takes a candidate solution as an argument in the form of a vector of real numbers and produces a real number as yield which indicates the objective function value of the given applicant solution. The gradient off is not known. The goal is to find a solution a for which f(a) ≤ f(b) for all b in the search-space, which would mean a is the universal minimum.Maximizationcanbemade by considering the function h = -f instead. Let S be the number of particles in the swarm,eachhaving a position xi ∈ Rn in the search space and a swiftnessvi ∈Rn. Let pi be the best-known position of particleiandletg bethe best-known position of the entire swarm. A basic PSO algorithm is then: For each particle i = 1, ..., S do: Initialize the particle's location with a uniformly distributed random vector: xi ~ U(blo, bup), where blo and bup are the lower and upper boundaries of the search-space. Set the particle's best known position to its primary position: pi ← xi If (f(pi) < f(g)) update theswarm'sbestknownposition: g ← pi Initialize the particle's velocity: vi ~ U(-|bup-blo|, |bup- blo|) Until a expiry criterion is met (e.g. number of iterations performed, or a solution with adequate objective function value is found), repeat: For each particle i = 1, ..., S do: For each dimension d = 1, ..., n do: Élite random numbers: rp, rg ~ U(0,1) Update the particle's velocity: vi,d← ωvi,d+φprp (pi,d-xi,d) + φg rg (gd-xi,d) Keep posted the particle's position: xi ← xi + vi If (f(xi) < f(pi)) do: Apprise the particle's best known position: pi ←xi If (f(pi) < f(g)) update the swarm's best known position: g ← pi Now g holds the best-found result. The parameters ω, φp, and φg are selected bytheexpertand control the behavior and efficacy of the PSO method. 2.7 MEDIAN FILTER A median filter is used to preserve edges while eliminating random clatters present in the image. For a two- dimensional image, the pictures are of 3-by-3 neighborhood value. The median filter swaps each entrywiththemedianof the neighboring entries. 2.8 SEGMENTATION Image segmentation is the process of partitioning a digital image into multiple segments  THRESHOLDING The simplest thresholding methods replace each pixel in an image with a black pixel if the image intensity is fewer than some static constant T or a white pixel if the image intensity is greater than that constant. Here, instead ofusing a local threshold value we use a formulated global threshold value.  EDGE SEGMENTATION Image processing is any form of information processing for which the input is an image, such as frames of video; the output is not necessarily an image but can be a set of features giving information about the image. Since images contain lots of redundant data,scholarshavediscoveredthat the most important information lies in its edges. Edges typically correspond to points in the image where the gray value changes significantly from one pixel to the next. 3 RESULT 3.1Analysis of a Normal or Healthy abdomen image: (a) Input Image
  • 4. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056 Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072 © 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 1494 (b) Pre-processed image (c) Segmented image (d) Classification (e) Optimized Image (f) Output 3.2 Analysis of abnormal or infected abdomen image: (a) Input Image (b) Pre-processed image (a) Segmented image
  • 5. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395 -0056 Volume: 04 Issue: 03 | Mar -2017 www.irjet.net p-ISSN: 2395-0072 © 2017, IRJET | Impact Factor value: 5.181 | ISO 9001:2008 Certified Journal | Page 1495 (d) Classification (e) Optimized Image (f) Output 4.CONCLUSION In this paper, we have detected the abnormalities in the abdomen using the wireless capsule endoscopy (WCE) images. The microscopic images of ulcer are examined by changes based on texture, geometry, colour, statically analysis used as the input. We have trainedandclassifiedthe microscopic images. This system is reliable and cost- effective. ACKNOWLEDGMENT: I sincerely thank my external guide and my internal guide for all their help and guidance and my project coordinators for giving me the opportunity to conduct my project work in Panimalar Institute of Technology. REFERNCES [1] A. Karargyris and N. Bourbakis, “Detection of small bowel polyps and ulcers in wireless capsule endoscopy videos,” Biomedical Engineering,IEEETransactionson, vol. 58, no. 10, pp. 2777–2786, 2011. [2] L. Zhang, Z. Gu, and H. Li, “Sdsp: A novel saliency detection method by combining simple priors.” in Image Processing (ICIP), 2013 20th IEEE International Conference on. IEEE, 2013, pp. 171–175. [3] S. Goferman, L. Zelnik-Manor, and A. Tal, “Context- aware saliency detection,” Pattern Analysis and Machine Intelligence, IEEE Transactions on, vol. 34, no. 10, pp. 1915–1926, 2012. [4] M.-M. Cheng, G.-X. Zhang, N. J. Mitra, X. Huang, and S.-M. Hu, “Global contrast based salient region detection,” in Computer Vision andPattern Recognition(CVPR),2011 IEEE Conference on. IEEE, 2011, pp. 409–416. [5] R. Achanta and S. Susstrunk, “Saliency detection using maximum symmetric surround,” in Image Processing (ICIP), 2010 17th IEEE International Conference on. IEEE, 2010, pp. 2653–2656. [6] R. Achanta, S. Hemami, F. Estrada, and S. Susstrunk, “Frequency-tuned salient region detection,” in Computer Vision and Pattern Recognition, 2009. CVPR 2009. IEEE Conference on. IEEE, 2009, pp. 1597–1604. [7] L. Zhang, M. H. Tong, T. K. Marks, H. Shan, and G. W. Cottrell, “Sun: A bayesian framework for saliency using natural statistics,” Journal of vision, vol. 8, no. 7, p. 32, 2008. [8] J. Harel, C. Koch, and P. Perona, “Graph-based visual saliency,” in Advances in neural informationprocessing systems, 2006, pp. 545–552. [9] L. Itti, C. Koch, and E. Niebur, “A model of saliency- based visual attention for rapid scene analysis,” IEEE Transactions on pattern analysis and machine intelligence, vol. 20, no. 11, pp. 1254–1259, 1998. [10] S. Lazebnik, C. Schmid, and J. Ponce, “Beyond bags of features: Spatial pyramid matching for recognizing natural scene categories,” in Computer Vision and Pattern Recognition, 2006 IEEE Computer Society Conference on, vol. 2. IEEE, 2006, pp. 2169–2178. [11] Y. Yuan and M. Q.-H. Meng, “Polyp classification based on bag of features and saliency in wireless capsule endoscopy,” in Robotics and Automation (ICRA), 2014 IEEE International Conference on. IEEE, 2014, pp. 3930–3935. [12] T. Ma, Y. Zou, Z. Xiang, L. Li, and Y. Li, “Wireless capsule endoscopy image classification based on vector sparse coding,” in Signal and Information Processing (ChinaSIP), 2014 IEEE China Summit & International Conference on. IEEE, 2014, pp. 582–586. [13] M. Safdari, R. Pasari, D. Rubin,andH.Greenspan,“Image patch-based method for automated classification and detection of focal liver lesions on ct,” in SPIE Medical Imaging. International SocietyforOpticsandPhotonics, 2013, pp. 86 700Y–86 700Y. [14] J. Wang, Y. Li, Y. Zhang, C. Wang, H. Xie, G. Chen, X. Gao, et al., “Bag-of-features based medical image retrieval via multiple assignment and visual words weighting,” IEEE transactions on medical imaging, vol. 30, no. 11, pp. 1996–2011, 2011. [15] J. Wang, J. Yang, K. Yu, F. Lv, T. Huang, and Y. Gong, “Localityconstrained linear coding for image classification,” in Computer Vision and Pattern Recognition (CVPR), 2010 IEEE Conference on. IEEE, 2010, pp. 3360–3367. [16] A. P. Moore, S. Prince, J. Warrell, U. Mohammed, and G. Jones, “Super-pixel lattices,” in Computer Vision and Pattern Recognition, 2008. CVPR 2008. IEEE Conference on. IEEE, 2008, pp. 1–8. [17] A. Levinshtein, A. Stere, K. N. Kutulakos, D. J. Fleet, S. J. Dickinson, and K. Siddiqi, “Turbopixels: Fast super- pixels using geometric flows,” Pattern Analysis and Machine Intelligence, IEEE Transactions on, vol. 31, no. 12, pp. 2290–2297, 2009. [18] L. Zhu, D. A. Klein, S. Frintrop, Z. Cao, and A. B. Cremers,
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