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IJSRD - International Journal for Scientific Research & Development| Vol. 2, Issue 08, 2014 | ISSN (online): 2321-0613
All rights reserved by www.ijsrd.com 252
Cleaner Production opportunities and its benefits in Biotech Industry
Ghatna Trivedi1
Ast Prof. Minerva Pandya2
1
M.E. [Environmental Management] Student 2
Assitant Professor
1,2
Department of Environmental Engineering
1,2
L.D. College of Engineering, Ahmedabad, Gujarat
Abstract— Biotechnology is said to be used as tool for
cleaner production. There has been much discussion
regarding potential environmental benefits and hazards
associated with biotechnology. Biotechnology is
increasingly being viewed as a major weapon against
environmental damage. Cleaner production is considered as
a part of this strategy and yet there is still widespread
ignorance about this emerging technology but there are
many areas in biotech industry where application of cleaner
production can be beneficial economically as well as
environmentally. There are many sectors of biotechnology;
each sector has different process and products. By analyzing
process of each class of biotechnology, Cleaner production
opportunities can be generated specifically. Major processes
in this industry where cleaner production can be applied are
heat transfer, mass transfer, mechanical operations,
separation techniques, etc. cleaner production at smaller
level may also leads to benefits in overall economy and
waste minimization in process. Cleaner production aims at
waste reduction, onsite recovery, product modification and
energy conservation. Although there are several barriers to
cleaner production but it can be overcome considering the
benefits obtained from cleaner production.
Keywords: Cleaner production, Biotechnology, waste
minimization
I. INTRODUCTION
Cleaner production is the maximum feasible reduction of all
waste generated at production sites. It involves judicious use
of resources through reuse of material, source reduction,
water conservation; energy efficiency, etc. preventing or
recycling at the source eliminates the need for off-site
treatment and disposal. Elimination of pollutants at source is
typically less expensive than waste collecting, treating and
disposal. Cleaner production facilitates conservation of
energy and raw material, cost reduction, increase in
efficiency, sound environmental process, etc. The concept of
'biotech' or 'biotechnology' encompasses a wide range of
procedures for modifying living organisms according to
human purposes — going back to domestication of animals,
cultivation of plants, and "improvements" to these through
breeding programs that employ artificial
selection and hybridization. Modern usage also
includes tissue culture technologies as well as cell and
genetic engineering.
II. BIOTECHNOLOGY
Biotechnology is defined by the American Chemical Society
as the application of biological process, biological systems
or organisms by various industries to learning about the
science of life and the improvement of the value of materials
and organisms such as crops, livestock, and
pharmaceuticals. Biotechnology is being used to engineer
and adapt organisms, especially microorganisms, in an effort
to find sustainable ways to clean up contaminated
environments.
CLASS OF
BIOTECHNOLOGY
EXAMPLE
Red
Genetic engineering,
antibiotic production, etc
White/Grey Industrial enzyme production
Green
Transgenic plants, tissue
culture, etc
Blue
Aquatic or Marine
biotechnology
Table 1: Classes of Biotechnology
The elimination of a wide range of pollutants and
wastes from the environment is an absolute requirement to
promote a sustainable development of our society with low
impact on environment. Biological processes play a major
role in the removal of contaminants. Biotechnology makes
use of catabolic versatility of microorganisms and their
ability to degrade/convert compounds. New methodological
breakthroughs in genomics, proteomics, sequencing,
bioinformatics and imaging are producing vast amounts of
information. In the field of Microbiology, genomic studies
opens a new era providing unprecedented in silico views of
metabolic and regulatory networks. Microbiology also offers
clues to the evolution of degradation pathways and to the
molecular adaptation strategies to changing environmental
situations.
Generally Biotechnology Classes Below:
Red Biotech: is applied to medical processes. Some
examples are the engineering of genetic cures through
genomic manipulation, and the designing of organisms to
produce antibiotics.
White/Grey Biotech: applied to industrial
processes. An example of it is the organism designed to
produce a useful chemical.
Green Biotech: applied to agricultural processes.
An example is transgenic plants designed in such a way to
grow under specific environmental conditions or in the
presence (or absence) of certain agricultural chemicals.
Blue Biotech: It describe the marine, aquatic
applications of biotechnology.
III. BIOTECHNOLOGY AS TOOL FOR CLEANER PRODUCTION
Research works and industrial data regarding industry, both
say that biotechnology can be used as a tool for cleaner
production. Biotechnology is competitive with and in many
cases complements chemical methods for achieving clean
technologies. Biotechnology is a technology that provides
powerful routes to clean industrial
products and processes and is expected to play a
growing role. Biotechnological operations are now used in
a wide range of major industrial processes. Applications
Cleaner Production opportunities and its benefits in Biotech Industry
(IJSRD/Vol. 2/Issue 08/2014/058)
All rights reserved by www.ijsrd.com 253
tend to be industrial-sector specific; the report addresses
chemicals and Pharmaceuticals, textiles and leather, food
and feeds, metals and minerals, pulp and paper, and energy.
Biotechnology-based processes have been successfully
integrated into large-scale operations. Industrial penetration
of biotechnology is increasing as a consequence of advances
in recombinant DNA technologies. Biotechnological
operations have lead to cleaner processes with low waste
generation and in some cases lower energy consumption. In
industrial process such as Ammonium acrylate is the key
intermediate in the manufacture of acrylic polymers, is made
by hydrolyzing acrylonitrile to acrylic acid and reacting this
with ammonia. The reaction is energy-intensive and gives
rise to by-products which are difficult in removal. Process
based on a bacterial enzyme which directly Synthesises
ammonium acrylate of the same quality under less energy-
demanding conditions, has been Operating for several years
at full scale. And In paper making, treating cellulose fibers
in the pulp using cellulase and hemicellulasez enzymes
allows water to drain more quickly from the wet pulp which
reduce processing time and energy used for drying. Trials
have shown that machine speeds can be increased by up to 7
per cent and energy input reduced by as much as 7.5 per
cent. Replacing thermo mechanical pulping by biopulping
has resulted in up to 30 per cent reduction in electrical
energy consumption. Replacement of chemical process by
enzymatic process has been showing huge benefits like high
efficiency, reduced cost and time, minimized and
decomposable waste, etc.
IV. CLEANER PRODUCTION OPPORTUNITIES IN BIOTECH
INDUSTRY
Although biotechnology is said to be used as tool for cleaner
production there is a scope for cleaner production in biotech
industry itself. There are few processes which are common
in each industry where there is scope of cleaner production.
Major processes where cleaner production can be applied
are heat transfer, mass transfer, unit operations etc. heat
transfer operations includes conduction, convection,
condensation, etc. use of shell and tube heat exchanger in
case of such operation where heating and cooling required
continuously, lot of energy in separate heating and cooling
can be saved by using single reactor for same purpose. Mass
transfer operations like distillation, evaporation, extraction,
drying, etc where cleaner production opportunities can be
generated. In case of mass transfer operations, by changing
method or composition of processing product, efficiency of
production can be increased. There are Mechanical
operations such as size reduction, sedimentation, and
filtration where in cleaner production opportunities are
there. Several separation techniques are used in biotech
industry such as
Heat transfer Conduction, convection, condensation
Mass transfer Distillation, extraction, drying
Mechanical
operations
Size reduction, sedimentation,
filtration
Separation
techniques
HPLC, GLC and other
chromatographic techniques
Fermentation Lab scale and industry scale.
Table 2: Operations in biotech industry where cleaner
production can be possible.
HPLC, GLC, and other chromatographic
techniques for the separation of pure compound. By
changing concentration and flow of material through system
can result in to efficient and energy saving process.
Fermentation is widely used in industrial biotech companies;
if batch process is used instead of continuous process fewer
raw materials is required comparatively. Likewise adoption
of few basic techniques of cleaner production such as good
housekeeping, use of waste as raw material for other
product, material recovery from waste, product reformation,
change in product composition if possible and energy
conservation may lead to drastic benefits like increased
productivity, high efficiency, lower waste generation,
energy conservation, gaining economical benefits,
improving environmental situations, etc.
V. CONCLUSION
Biotechnology as an emerging field has large scope of new
technologies with cleaner production in order to minimize
waste and conserve energy. Although biotechnology is
repeatedly being viewed as tool for cleaner production there
are numerous chances of cleaner production in process of
biotechnology itself. It is mutual benefit process when
biotech used as tool to cleaner production or cleaner
production used in biotech process. Considering the benefits
obtained from it like waste minimization a reuse, energy
conservation, pollution reduction adoption of cleaner
production in every industry is convincing including
biotechnology. Limitation in biotech industry is there are
certain process where process cannot be altered, parameters
to be strictly followed and reutilization is strictly prohibited.
By developing better attitude towards cleaner production in
this field numerous benefits can surely be achieved.
REFERENCE
[1] BRAITHWAITE, M.J. "Waste Minimisation – the
Industrial Approach." (Chemistry of Waste
minimization) 7 (1995).
[2] OECD. "Technologies for Cleaner Production and
Products." (OECD) 1995.
[3] Phineas Masango. "Cleaner production of essential
oils by steam distillation." (Journal of Cleaner
Production ) 13 (2004).
[4] Ribas canal x., Muxach navvaro J. and Junka Riuro.
"new process for gelatin production using innovative
technology achieving an important reduction in
[5] environmental impact." (chemical engeeniring
transections) 7 (2005): 495-497.
[6] Subrata Basu1, Mukhopadhyay Swapan Kumar1,
Gangopadhyay Amitava1 and Dastidar Sujata G.4.
"Materials Saving and Waste Minimization in Indian
Pharmaceutical Industries." (Research Journal of
Pharmaceutical Sciences) 2 (February (2013)): 20-25.
[7] Nodubuisi Ezejiofor Tobias I Duru Carissa I.,
Asagbra Agnes Waste to wealth: Production of
oxytetracycline using streptomyces species from
household kitchen wastes of agricultural produce
[Journal]. - [s.l.] : African Journal of biotechnology,
2012. - 43 : Vol. 11
[8] L. P. Gianessi, C. S. Silvers, S. Sankula and J. E.
Carpenter. Plant Biotechnology: Current and
Cleaner Production opportunities and its benefits in Biotech Industry
(IJSRD/Vol. 2/Issue 08/2014/058)
All rights reserved by www.ijsrd.com 254
Potential Impact for Improving Pest management in
US Agriculture, An Analysis of 40 Case
Studies (Washington, D.C.: National Center for Food
and Agricultural Policy, 2002)
[9] Johannes Fresner Stenum GmbH, Cleaner production
as a means for effective environmental management,
Geidorfgürtel 21, A-8010 Graz, Austria
[10]Gudolf Kjaerheim,
Cecilia Askham Nyland, Cleaner
production and sustainability, Institute for
Environmental Protection, Oestfold Research
Foundation, Post Box 276, 1601 Fredrikstad, Norway
[11]Cleaner Production Guide for Hospitals - July 1997
Minimizing waste, reducing costs and caring for the
environment

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Cleaner Production opportunities and its benefits in Biotech Industry

  • 1. IJSRD - International Journal for Scientific Research & Development| Vol. 2, Issue 08, 2014 | ISSN (online): 2321-0613 All rights reserved by www.ijsrd.com 252 Cleaner Production opportunities and its benefits in Biotech Industry Ghatna Trivedi1 Ast Prof. Minerva Pandya2 1 M.E. [Environmental Management] Student 2 Assitant Professor 1,2 Department of Environmental Engineering 1,2 L.D. College of Engineering, Ahmedabad, Gujarat Abstract— Biotechnology is said to be used as tool for cleaner production. There has been much discussion regarding potential environmental benefits and hazards associated with biotechnology. Biotechnology is increasingly being viewed as a major weapon against environmental damage. Cleaner production is considered as a part of this strategy and yet there is still widespread ignorance about this emerging technology but there are many areas in biotech industry where application of cleaner production can be beneficial economically as well as environmentally. There are many sectors of biotechnology; each sector has different process and products. By analyzing process of each class of biotechnology, Cleaner production opportunities can be generated specifically. Major processes in this industry where cleaner production can be applied are heat transfer, mass transfer, mechanical operations, separation techniques, etc. cleaner production at smaller level may also leads to benefits in overall economy and waste minimization in process. Cleaner production aims at waste reduction, onsite recovery, product modification and energy conservation. Although there are several barriers to cleaner production but it can be overcome considering the benefits obtained from cleaner production. Keywords: Cleaner production, Biotechnology, waste minimization I. INTRODUCTION Cleaner production is the maximum feasible reduction of all waste generated at production sites. It involves judicious use of resources through reuse of material, source reduction, water conservation; energy efficiency, etc. preventing or recycling at the source eliminates the need for off-site treatment and disposal. Elimination of pollutants at source is typically less expensive than waste collecting, treating and disposal. Cleaner production facilitates conservation of energy and raw material, cost reduction, increase in efficiency, sound environmental process, etc. The concept of 'biotech' or 'biotechnology' encompasses a wide range of procedures for modifying living organisms according to human purposes — going back to domestication of animals, cultivation of plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes tissue culture technologies as well as cell and genetic engineering. II. BIOTECHNOLOGY Biotechnology is defined by the American Chemical Society as the application of biological process, biological systems or organisms by various industries to learning about the science of life and the improvement of the value of materials and organisms such as crops, livestock, and pharmaceuticals. Biotechnology is being used to engineer and adapt organisms, especially microorganisms, in an effort to find sustainable ways to clean up contaminated environments. CLASS OF BIOTECHNOLOGY EXAMPLE Red Genetic engineering, antibiotic production, etc White/Grey Industrial enzyme production Green Transgenic plants, tissue culture, etc Blue Aquatic or Marine biotechnology Table 1: Classes of Biotechnology The elimination of a wide range of pollutants and wastes from the environment is an absolute requirement to promote a sustainable development of our society with low impact on environment. Biological processes play a major role in the removal of contaminants. Biotechnology makes use of catabolic versatility of microorganisms and their ability to degrade/convert compounds. New methodological breakthroughs in genomics, proteomics, sequencing, bioinformatics and imaging are producing vast amounts of information. In the field of Microbiology, genomic studies opens a new era providing unprecedented in silico views of metabolic and regulatory networks. Microbiology also offers clues to the evolution of degradation pathways and to the molecular adaptation strategies to changing environmental situations. Generally Biotechnology Classes Below: Red Biotech: is applied to medical processes. Some examples are the engineering of genetic cures through genomic manipulation, and the designing of organisms to produce antibiotics. White/Grey Biotech: applied to industrial processes. An example of it is the organism designed to produce a useful chemical. Green Biotech: applied to agricultural processes. An example is transgenic plants designed in such a way to grow under specific environmental conditions or in the presence (or absence) of certain agricultural chemicals. Blue Biotech: It describe the marine, aquatic applications of biotechnology. III. BIOTECHNOLOGY AS TOOL FOR CLEANER PRODUCTION Research works and industrial data regarding industry, both say that biotechnology can be used as a tool for cleaner production. Biotechnology is competitive with and in many cases complements chemical methods for achieving clean technologies. Biotechnology is a technology that provides powerful routes to clean industrial products and processes and is expected to play a growing role. Biotechnological operations are now used in a wide range of major industrial processes. Applications
  • 2. Cleaner Production opportunities and its benefits in Biotech Industry (IJSRD/Vol. 2/Issue 08/2014/058) All rights reserved by www.ijsrd.com 253 tend to be industrial-sector specific; the report addresses chemicals and Pharmaceuticals, textiles and leather, food and feeds, metals and minerals, pulp and paper, and energy. Biotechnology-based processes have been successfully integrated into large-scale operations. Industrial penetration of biotechnology is increasing as a consequence of advances in recombinant DNA technologies. Biotechnological operations have lead to cleaner processes with low waste generation and in some cases lower energy consumption. In industrial process such as Ammonium acrylate is the key intermediate in the manufacture of acrylic polymers, is made by hydrolyzing acrylonitrile to acrylic acid and reacting this with ammonia. The reaction is energy-intensive and gives rise to by-products which are difficult in removal. Process based on a bacterial enzyme which directly Synthesises ammonium acrylate of the same quality under less energy- demanding conditions, has been Operating for several years at full scale. And In paper making, treating cellulose fibers in the pulp using cellulase and hemicellulasez enzymes allows water to drain more quickly from the wet pulp which reduce processing time and energy used for drying. Trials have shown that machine speeds can be increased by up to 7 per cent and energy input reduced by as much as 7.5 per cent. Replacing thermo mechanical pulping by biopulping has resulted in up to 30 per cent reduction in electrical energy consumption. Replacement of chemical process by enzymatic process has been showing huge benefits like high efficiency, reduced cost and time, minimized and decomposable waste, etc. IV. CLEANER PRODUCTION OPPORTUNITIES IN BIOTECH INDUSTRY Although biotechnology is said to be used as tool for cleaner production there is a scope for cleaner production in biotech industry itself. There are few processes which are common in each industry where there is scope of cleaner production. Major processes where cleaner production can be applied are heat transfer, mass transfer, unit operations etc. heat transfer operations includes conduction, convection, condensation, etc. use of shell and tube heat exchanger in case of such operation where heating and cooling required continuously, lot of energy in separate heating and cooling can be saved by using single reactor for same purpose. Mass transfer operations like distillation, evaporation, extraction, drying, etc where cleaner production opportunities can be generated. In case of mass transfer operations, by changing method or composition of processing product, efficiency of production can be increased. There are Mechanical operations such as size reduction, sedimentation, and filtration where in cleaner production opportunities are there. Several separation techniques are used in biotech industry such as Heat transfer Conduction, convection, condensation Mass transfer Distillation, extraction, drying Mechanical operations Size reduction, sedimentation, filtration Separation techniques HPLC, GLC and other chromatographic techniques Fermentation Lab scale and industry scale. Table 2: Operations in biotech industry where cleaner production can be possible. HPLC, GLC, and other chromatographic techniques for the separation of pure compound. By changing concentration and flow of material through system can result in to efficient and energy saving process. Fermentation is widely used in industrial biotech companies; if batch process is used instead of continuous process fewer raw materials is required comparatively. Likewise adoption of few basic techniques of cleaner production such as good housekeeping, use of waste as raw material for other product, material recovery from waste, product reformation, change in product composition if possible and energy conservation may lead to drastic benefits like increased productivity, high efficiency, lower waste generation, energy conservation, gaining economical benefits, improving environmental situations, etc. V. CONCLUSION Biotechnology as an emerging field has large scope of new technologies with cleaner production in order to minimize waste and conserve energy. Although biotechnology is repeatedly being viewed as tool for cleaner production there are numerous chances of cleaner production in process of biotechnology itself. It is mutual benefit process when biotech used as tool to cleaner production or cleaner production used in biotech process. Considering the benefits obtained from it like waste minimization a reuse, energy conservation, pollution reduction adoption of cleaner production in every industry is convincing including biotechnology. Limitation in biotech industry is there are certain process where process cannot be altered, parameters to be strictly followed and reutilization is strictly prohibited. By developing better attitude towards cleaner production in this field numerous benefits can surely be achieved. REFERENCE [1] BRAITHWAITE, M.J. "Waste Minimisation – the Industrial Approach." (Chemistry of Waste minimization) 7 (1995). [2] OECD. "Technologies for Cleaner Production and Products." (OECD) 1995. [3] Phineas Masango. "Cleaner production of essential oils by steam distillation." (Journal of Cleaner Production ) 13 (2004). [4] Ribas canal x., Muxach navvaro J. and Junka Riuro. "new process for gelatin production using innovative technology achieving an important reduction in [5] environmental impact." (chemical engeeniring transections) 7 (2005): 495-497. [6] Subrata Basu1, Mukhopadhyay Swapan Kumar1, Gangopadhyay Amitava1 and Dastidar Sujata G.4. "Materials Saving and Waste Minimization in Indian Pharmaceutical Industries." (Research Journal of Pharmaceutical Sciences) 2 (February (2013)): 20-25. [7] Nodubuisi Ezejiofor Tobias I Duru Carissa I., Asagbra Agnes Waste to wealth: Production of oxytetracycline using streptomyces species from household kitchen wastes of agricultural produce [Journal]. - [s.l.] : African Journal of biotechnology, 2012. - 43 : Vol. 11 [8] L. P. Gianessi, C. S. Silvers, S. Sankula and J. E. Carpenter. Plant Biotechnology: Current and
  • 3. Cleaner Production opportunities and its benefits in Biotech Industry (IJSRD/Vol. 2/Issue 08/2014/058) All rights reserved by www.ijsrd.com 254 Potential Impact for Improving Pest management in US Agriculture, An Analysis of 40 Case Studies (Washington, D.C.: National Center for Food and Agricultural Policy, 2002) [9] Johannes Fresner Stenum GmbH, Cleaner production as a means for effective environmental management, Geidorfgürtel 21, A-8010 Graz, Austria [10]Gudolf Kjaerheim, Cecilia Askham Nyland, Cleaner production and sustainability, Institute for Environmental Protection, Oestfold Research Foundation, Post Box 276, 1601 Fredrikstad, Norway [11]Cleaner Production Guide for Hospitals - July 1997 Minimizing waste, reducing costs and caring for the environment