Thyroid Storm

INTRODUCTION ,[object Object],[object Object],[object Object],[object Object]

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Etiology ,[object Object],[object Object],[object Object],[object Object],[object Object]

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Mortality/Morbidity ,[object Object],[object Object]

Signs and Symptoms Thyroid Storm Uncomplicated Thyrotoxicosis Confusion, agitation, delirium, frank psychosis, seizures, stupor or coma Anxiety, restlessness Nausea, vomiting, severe diarrhea, abdominal pain, hepatocellular dysfunction-jaundice Diarrhea, increased appetite with loss of weight Heart rate faster than 140 beats/min, hypotension, atrial dysrhythmias, congestive heart failure Sinus tachycardia, heart rate 100-140 Hyperpyrexia, temperature in excess of 106 o C, dehydration Heat intolerance, diaphoresis

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[object Object],[object Object],[object Object],[object Object],[object Object],Signs and Symptoms

Pathophysiology Hyperthyroid state Precipitating factor Increase in thyroid hormone (shift from protein bound to free hormone) Sudden increase in metabolism End organ damage Exaggerated SSx of hyperthyroidism

Predisposing factors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Management ,[object Object],[object Object],[object Object]

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Lab Studies ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Thyroid Storm

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