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MANAGEMENT OF POST 
OPERATIVE WOUND INFECTION 
(SURGICAL SITE INFECTION) 
DR BASHIR YUNUS 
20/11/14 
bbinyunus2002@gmail.com 1 11/23/2014
 INTRODUCTION 
 DEFINITION 
 EPIDIMIOLOGY 
 CLASSIFICATION 
 PATHOGENESIS 
 RISK FACTORS 
 MICROBIOLOGY 
 MANAGEMENT 
 HISTORY 
 PHYSICAL EXAMINATION 
 INVESTIGATION 
 TREATMENT 
 PREVENTION 
 CONCLUSION 
 REFERENCES 
OUTLINE 
bbinyunus2002@gmail.com 2 11/23/2014
INTRODUCTION 
 It is defined as infection present in any location along 
the surgical tract after a surgical procedure within 
30days of procedure or up to 1 year after a procedure 
that has involved an implant. 
bbinyunus2002@gmail.com 3 11/23/2014
INTRODUCTION 
 Incidence vary from center to center. 
 About 2-5% develop SSI in US accounting for about 
300,000-500,000 patient per annum 
 2nd most common type of Hospital Associated 
infection. 
bbinyunus2002@gmail.com 4 11/23/2014
INTRODUCTION 
 CLASSIFICATION 
 INCISIONAL 
 Superficial (skin and subcutaneous ) 
 Deep (fascia and muscle) 
 ORGAN/SPACE 
 Involves any part of anatomy in organs and spaces other 
than the incision which was opened or manipulated during 
operation. 
bbinyunus2002@gmail.com 5 11/23/2014
 CRITERIA 
INTRODUCTION 
 The above classification, each class is accompanied by at 
least one of the following; 
 Purulent discharge with or without laboratory 
confirmation. 
 Organism isolated from aseptically obtained culture 
 At least one of the signs of inflammation 
 Spontaneous wound dehiscence or delibrate opening by 
the attending surgeon 
 Diagnosis by the attending surgeon 
bbinyunus2002@gmail.com 6 11/23/2014
bbinyunus2002@gmail.com 7 11/23/2014
INTRODUCTION 
 RISK FACTORS 
 GENERAL/ PATIENT FACTORS 
 LOCAL FACTORS 
 MICROBIAL FACTORS 
bbinyunus2002@gmail.com 8 11/23/2014
 PATIENT FACTORS 
 Age; elderly 
 malnutrition 
 Obesity 
 DM 
 Malignancy 
 Prolonged steroid use 
 Immunosuppressive diseases 
 Anaemia 
 Chronic inflammatory diseases 
bbinyunus2002@gmail.com 9 11/23/2014
 LOCAL FACTORS 
 Poor skin preparation 
 Bridge of asepsis 
 Contaminated instrument 
 Prolong procedure(>2hrs) 
 Poor surgical technique 
 Operation on an infected organ: TIP, perforated appendicitis 
 Foreign body 
 Local tissue necrosis 
bbinyunus2002@gmail.com 10 11/23/2014
 MICROBIAL FACTOR 
 Virulence 
 Bacterial resistance 
 Dose of inoculum 
 Pre-existing remote body site infection 
bbinyunus2002@gmail.com 11 11/23/2014
MICRO-ORGANISMS 
 Depends on the type of surgical procedure 
 Clean : staph aureus (commonest) 
 Exogenous source 
 Skin flora 
 Clean-contaminated, contaminated and dirty wound : 
polymicrobial- anaerobes and aerobes 
 E. coli 
 Proteus 
 Psedomonas 
 bacteroides 
bbinyunus2002@gmail.com 12 11/23/2014
 History 
MANAGEMENT 
 Pain, fever, discharge usually about 5th day post 
operatively (5-7days) 
 However, infection can be seen within 48hours(within 6- 
8hrs) with organisms such as clostridium, bacteriodes, β- 
hemolytic streptococcus and coliforms. 
 History of risk factors as mentioned,co-morbidities. 
bbinyunus2002@gmail.com 13 11/23/2014
MANAGEMENT 
 Physical examination 
 GPE 
 Wasted 
 Obese 
 febrile 
 Anaemic 
 Dehydrated 
 Pedal oedema 
bbinyunus2002@gmail.com 14 11/23/2014
 Systemic 
MANAGEMENT 
 Systemic involvement- septicemia 
 Pre-existing remote infection 
 LOCAL 
 Oedema 
 Hyperamia 
 Discharge 
 Gapping wound edges 
 tenderness 
bbinyunus2002@gmail.com 15 11/23/2014
INVESTIGATION 
 WOUND SWAB MCS 
 WOUND BIOPSY 
 FBC- leukocytosis, or leukopenia 
 U/Ecr – hyponatremia in necrotising fasciitis 
 USS- intra abdominal uss 
 CTSCAN 
bbinyunus2002@gmail.com 16 11/23/2014
Treatment 
 Sutures in the infected part are removed for free drainage 
of pus, expressed 
 Wound swab is taken for MCS (other investigations are 
requested base on the assessment of the attending surgeon) 
FBC, U/E, USS, serum protein, wound biopsy-mcs 
 Placed on broad spectrum antibiotics pending the result of 
mcs 
 Wound dressing(frequency depends on degree of 
infection) and debridement of necrotic tissues. 
 Correction of anaemia if present other derangements 
bbinyunus2002@gmail.com 17 11/23/2014
PREVENTION 
 It is better prevented than treated 
 Prevention starts pre-operatively, intra and post-operatively 
bbinyunus2002@gmail.com 18 11/23/2014
PREVENTION 
 PRE-OPERATIVE 
 Short pre-operative hospital stay 
 Pre-op antiseptic shower 
 Pre-op hair removal 
 Pre-op bowel preparation 
 Pre-op antibiotics 
 Tight glucose control 
 Optimize nutrition 
 Stop smoking 
bbinyunus2002@gmail.com 19 11/23/2014
PREVENTION 
 INTRA-OPERATIVE 
 Strict asepsis 
 Skin preparation 
 Gowning and draping 
 Good surgical technique 
 Dead space 
 Appropriate sutures 
 Debridement 
 Approximate not strangulate 
 Justify use of drain 
 Delay primary closure when indicated 
 Supplemental O₂, adequte fluid resuscitation, 
bbinyunus2002@gmail.com 20 11/23/2014
PREVENTION 
 POST-OPERATIVE 
 Protect wound for 1st 48hrs then inspect, however if 
dressing is soaked, change dressing. 
 Early enteral nutrition 
 Tight glucose control 
 Surveillance programme 
bbinyunus2002@gmail.com 21 11/23/2014
COMPLICATIONS 
 Abscess 
 Septicemia 
 Sinus 
 Synergistic gangrene 
 Wound dehiscence 
 Weak and ugly scar 
bbinyunus2002@gmail.com 22 11/23/2014
CONCLUSION 
 SSI is a common preventable post operative 
complication which prolong hospital stay, hence cost 
medical care as well as other complications. 
 Risk factors should taken into consideration for 
appropriate prevention and prompt treatment went 
it occur. 
bbinyunus2002@gmail.com 23 11/23/2014
REFERENCES 
 E.A. Badoe, E.Q. Arcampompong, J.T Rocha; “Principles and Practice of 
surgery including pathology in the tropics”. 4th edition, Assembly of God 
Literature Center ltd 237-238 
 F Charles et tal “schwart’s principles of surgery” tenth edition, Mc 
Graw Hill Education. 
 www.wikipedia.com 
 www.slideshare.net 
bbinyunus2002@gmail.com 24 11/23/2014

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Management of post operative wound infection

  • 1. MANAGEMENT OF POST OPERATIVE WOUND INFECTION (SURGICAL SITE INFECTION) DR BASHIR YUNUS 20/11/14 bbinyunus2002@gmail.com 1 11/23/2014
  • 2.  INTRODUCTION  DEFINITION  EPIDIMIOLOGY  CLASSIFICATION  PATHOGENESIS  RISK FACTORS  MICROBIOLOGY  MANAGEMENT  HISTORY  PHYSICAL EXAMINATION  INVESTIGATION  TREATMENT  PREVENTION  CONCLUSION  REFERENCES OUTLINE bbinyunus2002@gmail.com 2 11/23/2014
  • 3. INTRODUCTION  It is defined as infection present in any location along the surgical tract after a surgical procedure within 30days of procedure or up to 1 year after a procedure that has involved an implant. bbinyunus2002@gmail.com 3 11/23/2014
  • 4. INTRODUCTION  Incidence vary from center to center.  About 2-5% develop SSI in US accounting for about 300,000-500,000 patient per annum  2nd most common type of Hospital Associated infection. bbinyunus2002@gmail.com 4 11/23/2014
  • 5. INTRODUCTION  CLASSIFICATION  INCISIONAL  Superficial (skin and subcutaneous )  Deep (fascia and muscle)  ORGAN/SPACE  Involves any part of anatomy in organs and spaces other than the incision which was opened or manipulated during operation. bbinyunus2002@gmail.com 5 11/23/2014
  • 6.  CRITERIA INTRODUCTION  The above classification, each class is accompanied by at least one of the following;  Purulent discharge with or without laboratory confirmation.  Organism isolated from aseptically obtained culture  At least one of the signs of inflammation  Spontaneous wound dehiscence or delibrate opening by the attending surgeon  Diagnosis by the attending surgeon bbinyunus2002@gmail.com 6 11/23/2014
  • 8. INTRODUCTION  RISK FACTORS  GENERAL/ PATIENT FACTORS  LOCAL FACTORS  MICROBIAL FACTORS bbinyunus2002@gmail.com 8 11/23/2014
  • 9.  PATIENT FACTORS  Age; elderly  malnutrition  Obesity  DM  Malignancy  Prolonged steroid use  Immunosuppressive diseases  Anaemia  Chronic inflammatory diseases bbinyunus2002@gmail.com 9 11/23/2014
  • 10.  LOCAL FACTORS  Poor skin preparation  Bridge of asepsis  Contaminated instrument  Prolong procedure(>2hrs)  Poor surgical technique  Operation on an infected organ: TIP, perforated appendicitis  Foreign body  Local tissue necrosis bbinyunus2002@gmail.com 10 11/23/2014
  • 11.  MICROBIAL FACTOR  Virulence  Bacterial resistance  Dose of inoculum  Pre-existing remote body site infection bbinyunus2002@gmail.com 11 11/23/2014
  • 12. MICRO-ORGANISMS  Depends on the type of surgical procedure  Clean : staph aureus (commonest)  Exogenous source  Skin flora  Clean-contaminated, contaminated and dirty wound : polymicrobial- anaerobes and aerobes  E. coli  Proteus  Psedomonas  bacteroides bbinyunus2002@gmail.com 12 11/23/2014
  • 13.  History MANAGEMENT  Pain, fever, discharge usually about 5th day post operatively (5-7days)  However, infection can be seen within 48hours(within 6- 8hrs) with organisms such as clostridium, bacteriodes, β- hemolytic streptococcus and coliforms.  History of risk factors as mentioned,co-morbidities. bbinyunus2002@gmail.com 13 11/23/2014
  • 14. MANAGEMENT  Physical examination  GPE  Wasted  Obese  febrile  Anaemic  Dehydrated  Pedal oedema bbinyunus2002@gmail.com 14 11/23/2014
  • 15.  Systemic MANAGEMENT  Systemic involvement- septicemia  Pre-existing remote infection  LOCAL  Oedema  Hyperamia  Discharge  Gapping wound edges  tenderness bbinyunus2002@gmail.com 15 11/23/2014
  • 16. INVESTIGATION  WOUND SWAB MCS  WOUND BIOPSY  FBC- leukocytosis, or leukopenia  U/Ecr – hyponatremia in necrotising fasciitis  USS- intra abdominal uss  CTSCAN bbinyunus2002@gmail.com 16 11/23/2014
  • 17. Treatment  Sutures in the infected part are removed for free drainage of pus, expressed  Wound swab is taken for MCS (other investigations are requested base on the assessment of the attending surgeon) FBC, U/E, USS, serum protein, wound biopsy-mcs  Placed on broad spectrum antibiotics pending the result of mcs  Wound dressing(frequency depends on degree of infection) and debridement of necrotic tissues.  Correction of anaemia if present other derangements bbinyunus2002@gmail.com 17 11/23/2014
  • 18. PREVENTION  It is better prevented than treated  Prevention starts pre-operatively, intra and post-operatively bbinyunus2002@gmail.com 18 11/23/2014
  • 19. PREVENTION  PRE-OPERATIVE  Short pre-operative hospital stay  Pre-op antiseptic shower  Pre-op hair removal  Pre-op bowel preparation  Pre-op antibiotics  Tight glucose control  Optimize nutrition  Stop smoking bbinyunus2002@gmail.com 19 11/23/2014
  • 20. PREVENTION  INTRA-OPERATIVE  Strict asepsis  Skin preparation  Gowning and draping  Good surgical technique  Dead space  Appropriate sutures  Debridement  Approximate not strangulate  Justify use of drain  Delay primary closure when indicated  Supplemental O₂, adequte fluid resuscitation, bbinyunus2002@gmail.com 20 11/23/2014
  • 21. PREVENTION  POST-OPERATIVE  Protect wound for 1st 48hrs then inspect, however if dressing is soaked, change dressing.  Early enteral nutrition  Tight glucose control  Surveillance programme bbinyunus2002@gmail.com 21 11/23/2014
  • 22. COMPLICATIONS  Abscess  Septicemia  Sinus  Synergistic gangrene  Wound dehiscence  Weak and ugly scar bbinyunus2002@gmail.com 22 11/23/2014
  • 23. CONCLUSION  SSI is a common preventable post operative complication which prolong hospital stay, hence cost medical care as well as other complications.  Risk factors should taken into consideration for appropriate prevention and prompt treatment went it occur. bbinyunus2002@gmail.com 23 11/23/2014
  • 24. REFERENCES  E.A. Badoe, E.Q. Arcampompong, J.T Rocha; “Principles and Practice of surgery including pathology in the tropics”. 4th edition, Assembly of God Literature Center ltd 237-238  F Charles et tal “schwart’s principles of surgery” tenth edition, Mc Graw Hill Education.  www.wikipedia.com  www.slideshare.net bbinyunus2002@gmail.com 24 11/23/2014