Corruption undermines healthcare systems and puts lives at risk. Studies show corruption has large financial costs and reduces access to healthcare. Corruption risk comes from the complexity of healthcare systems with multiple stakeholders and decision points, as well as imbalances of information. Transparency can help address corruption by supporting accountability, reducing corruption, and promoting equitable access to medicine. Critical areas for transparency include regulatory policies, prices, quality, quantities, and procurement data. Transparency solutions include harmonized regulation, greater access to information, and public reporting on anti-bribery programs. Transparency alone is not enough and must be accompanied by measures like integrity pacts and whistleblower protections.