This document summarizes an ex-ante assessment of the potential impact of genetically modified bananas resistant to Xanthomonas wilt in the Great Lakes region of Africa. It finds that farmers are aware of and willing to adopt GM bananas to resist the disease. The assessment estimates that initial adoption rates of the GM bananas would range from 21-70% across countries. It projects large economic benefits for both farmers and consumers from adoption, with consumers benefitting twice as much due to expected price reductions. The largest benefits are estimated for countries most affected by Xanthomonas wilt such as Uganda. Participatory breeding programs are seen as having high potential to increase adoption rates.