The document discusses partnering between academic organizations and industry on mHealth and wireless medical technology projects. It provides an overview of the Center for Health Information and Decision Systems (CHIDS) which partners with government agencies, private companies, and non-profits on various research projects related to health IT, mobile health, and healthcare analytics. The document then discusses specific opportunities for collaboration such as technology development, pilot programs, clinical trials, and applying for grants and contracts.

1. mHealth and Wireless Medical Technology Conference Workshop
Partnering with Academic Organizations
Kenyon Crowley, MBA, MS, CPHIMS
May 1, 2013

2. Agenda
 About
 Partnering with academic researchers/orgs
 Tech transfer
 Funding

3. Strategy
TechnologyPolicy
About CHIDS
Mission
 Research, analyze, and recommend solutions to
challenges surrounding the introduction and
integration of information and decision technologies
into the health care system
 Improve the practice and delivery of health care by
offering researched solutions that impact safety,
quality, access, efficiency, and ROI
Partner Ecosystem
 Federal and state agencies (HHS, NSF, DoD, State of
MD)
 Private corporations (CNMC, J&J, CareFirst BlueCross
BlueShield, Cisco, Small and Mid-Size firms)
 Not-for-profits (CDT, eHealth Initiative)
Resources
 Renowned scholars from multiple disciplines
 Research fellows, students
3
Lockheed Martin Briefing

4. Research Focus Areas
Impact and
Comparative
Effectiveness of
Health Information
Systems
New Models of
Care (ACO, HIE,
PCMH, Care
Transitions)
Healthcare
Analytics (Data-
driven Health
Services Insights,
Modeling,
Operations)
Consumers,
Quality &
Transparency, and
Social Media

5. Mobile Health Applications
 Diverse application of wireless and mobile
technologies designed to improve health
research, health care services and health
outcomes
 Not just mobile phones + apps
 A major focus for clinicians and policy makers
 May increase patient engagement, advance
patient monitoring, aid in chronic disease
management, and potentially reduce health
system costs.
 Clinicians can track therapeutic effectiveness
through remote monitoring applications (apps)
that gather, transmit, and analyze a patient’s
readings.
 Limited number of apps are constructed on
design principles that are theoretically derived,
and little is known about their effectiveness.
Image: Rock Health

6. Mobile Health Market
 Market forecasted to grow at a CAGR (compound annual
growth rate) of 40.4 % through 2015.
 85% US adults own mobile phone; 53% own smartphone.
 19% of smartphone owners have at least one health app on
their phone. Exercise, diet, and weight apps are the most
popular types.
 One in three cell phone owners (31%) have used their phone
to look for health information. (17% one year ago).
 According to a March 2013 study, the market for mHealth
services has now entered the commercialization phase and
will reach $26 billion globally by 2017.
 According to research by HIMSS Analytics, about half of all
doctors use mobile health apps, and a quarter of consumers
do.
- Pew Mobile Health Survey 2012
- Mercom 2013

7. Era of the Quantified Self and Trackers
Graphic credit: Pew

8. University collaborations
 Technology research and development
 Evaluations
 Pilots and clinical trials
 Teaming on grants and contracts
Impact
Research
Teaching

9. Technology / Product Development
 Integrating cutting edge science and expertise for
new or enhanced products
University
Labs +
Centers
Industry
Liaison

10. Evaluation
 What is the effectiveness, impact + value of this
solution?
 Research with a capital “R”
 Economic
 Inefficiencies in hospital communications
 Process
 Time and motion
 Workflow analysis
 Impact of nursing call systems
 Clinical
 Defining measures
 Usability

11. http://healthit.ahrq.gov/developmentmethodsguide
Usability

12. Pilots & Clinical Trials
 Research design
 Site selection
 Agreements
 Cohort management
 Data Analysis
 Institutional Review Board (IRB) navigation
 IRB is a committee designated by an institution to help assure the
protection of the rights and welfare of human subjects
 If sponsored by HHS: Federal regulations at 45 CFR Part 46 require that
applications and proposals involving human subjects research must be
evaluated in accordance with those regulations, with reference to the
risks to the subjects, the adequacy of protection against these risks, the
potential benefits of the research to the subjects and others, and the
importance of the knowledge gained or to be gained

13. Teaming for opportunities
 Grants
 Contracts
 Contract vehicles
 GWAC, IDIQ, Consortium
 Alignment!

14. Algorithms and modeling
 Modeling ICU systems and throughput
 Nurse call systems
 Predictive models for early identification diabetes “jumpers”
 Fraud identification algorithms
 University role:
 Assess and document the effectiveness and value of solution
 Explore, refine and test next generation advances to the predictive
model
 Assess behavioral aspects and usability of current approach and
recommend improvements

15. PHR + secure messaging pilot
 Assess pilot implementation of secure messaging
and PHR
 University role
 Design research and analytical strategy
 Manage trial
 Publish results and lessons learned

16. Mobile EHR for Cardiologists
 Company has an existing basic EHR and is seeking to build a
specialty-specific product
 Market assessment by MBA team
 Software requirements by research group
 University role:
 Financial and qualitative assessment of potential markets
 Design, manage and conduct focus groups including cardiologists and
cardiac nurses
 Assess policy: meaningful use, standards, relevant market
developments
 Document technical, functional requirements

17. University Tech Transfer Role
 Brings solutions to marketplace
 Pay to Protect IP – patents, trademarks, copyrights.
 Assist in the development of Business Plans and
commercialization strategy.
 Assist in getting additional grant funding to further
develop IP
 Create start-up company when appropriate vehicle for
commercialization.
 Assist in raising financing for company.
 Negotiate agreements with licensees.

18. Licensing
Typical Agreement Terms and Conditions:
 Licensing (to start-ups or large corporations):
- royalty paid to university based upon sales
attributable to IP – typically around 5% of
sales.
 Milestones – if license is exclusive then
minimum royalties typically apply as well as
development milestones (especially in drug
development).

19. What’s in it for the researchers
 Royalties (Ranges broadly)
 Additional funding to do research
 Peer acknowledgement
 Equity in start-up
Does little to get tenure other than as a result of the papers that may be
published on the on-going research, and sometimes publishing in itself is
a huge problem in commercialization.
 Younger profs focus is usually getting tenure, which is gained through
- Publishing papers
- Doing more research
- Teaching
Commercialization of IP is not always high on their list – has implications
for businesses who want to license/buy the IP and move the IP forward
in conjunction with the researchers.

20. Funding opportunities…

21. Zombies, Run!
• Top paid health and fitness apps #4
• Key = Fun

22. STTR / SBIR
 The programs’ goals are to:
 Stimulate technological innovation
 Foster technology transfer through cooperative R&D between
small businesses and research institutions;
 Increase private sector commercialization of innovations
derived from federal R&D
 Must be small business concern (< 500
employees)
 3 Phases
 Reference:
http://grants.nih.gov/grants/funding/sbirsttr1/20
13-2_SBIR-STTR-topics.pdf

23. STTR
 Applicant is a Small Business Concern
 Formal Cooperative R&D Effort
 Minimum 40% by small business
 Minimum 30% by U.S. research institution
 U.S. Research Institution
 College or University
 Other non-profit research organization
 Federal R&D center
 Phase 1 normally does not exceed $100,000 total costs for 1 year.
 Phase II awards normally do not exceed $750,000 total costs for 2
years.
 Intellectual Property Agreement
 Allocation of IP rights and rights to carry out follow-on R&D and
commercialization
 Principal Investigator’s primary employment may be with either the
Small Business Concern or the research institution

24.  Small Business Concern
 Organized for-profit U.S. business
 500 or fewer employees, including affiliates
 Must be:
 At least 51% U.S.- owned by individuals and independently operated
or
 At least 51% owned and controlled by another (one) business concern that
is at least 51% owned and controlled by one or more individuals
 Three Phase potential
 Principal Investigator’s primary employment must be with the Small
Business Concern
SBIR

25. MIPS
 The Maryland Industrial Partnerships (MIPS)
program accelerates the commercialization of
technology in Maryland by jointly funding
collaborative R&D projects between companies
and University System of Maryland faculty.
 mHealth Successes
 WellDocs
 TelCare

26. Open opportunities
 NSF Smart and Connected Health
 May 28, $170K direct costs/yr for 3 years
 Maryland Industrial Partnerships
 October 1
 SBIR/STTR
 HHS (NIH, FDA, CDC): August 5, December 5
 NIH and AHRQ
 R21 Research and Demonstration Grants: October 16
 $275K in direct costs over 2 years, max of $200k/yr
 TEDCO
 DARPA and other DoD

27. Questions + Contact
 Kenyon Crowley
 kcrowley@rhsmith.umd.edu
 Tel 919-649-2279
Thank you!

28. Additional stuff
 Fun and interesting apps
 Hot areas

29. Health Gaming

30. Cloud, API’s

31. Aging in Place
 Problem: Assessment of and intervention for
everyday functional limitations of persons with
early-stage dementia without need of assisted
living (aging in place)
 Solution: Automated wireless and fixed
monitoring and assistance to help people cope
with age-related limitations

32. Cardiac Disease Management
 Problem: Patients with CVD have symptoms that
frequently bring them to emergency care where
there is limited baseline data
 Solution: Remote monitoring to create
physiological cardiac activity “fingerprints” that
alert professionals and patient when there are
irregularities based on their own cardiac patterns
- Nilsen
- Shusterman