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Jack Newton	

      http://www.flickr.com/photos/jdn/5544977049/	





Influence: It s in Your Genes	

                                          How to own your genetic equity	

                                                  #DNAsxsw
Paul Saarinen                           Scott Fahrenkrug,	

Yamamoto, Director of Digital Strategy          PH.DUniversity of Minnesota, 	

     Partner, Zingstring.com             Director of the Animal Biotechnology Center	

                                                      Founder, Recombinetics
Demographic	
  and	
  psychographic	
  informa2on	
  
                      Age,	
  marital	
  status,	
  kids,	
  home	
  loca2on,	
  es2mated	
  salary,	
  	
  recently	
  
                      moved,	
  credit	
  cards,	
  web	
  sites,	
  ethnicity,	
  job	
  history,	
  magazines,	
  
                      bankruptcy,	
  divorce,	
  year	
  you	
  bought	
  (or	
  lost)	
  your	
  house,	
  college,	
  online	
  
                      discussion	
  topics,	
  brands	
  of	
  coffee,	
  paper	
  towels,	
  cereal	
  or	
  applesauce,	
  
                      poli2cal	
  leanings,	
  reading	
  habits,	
  charitable	
  giving,	
  number	
  of	
  cars,	
  
                      interests,	
  check-­‐ins,	
  groups,	
  and	
  friends.	
  


                                                                         	





All your data are belongs to us
Mark Zuckerberg has said they can determine
  within a 33% accuracy when you ll break up
           and who you ll start dating	

                      	

Facebook relationship prediction
Can predict with a 98% accuracy up to two
 years ahead of time if you’ll get a divorce	

                    	


        Credit databases
URSQUARE

 ict where you’ll go next based
orical check-in’s and friends
     activities




                  Wants to predict where you’ll go next	



                                  Foursquare
Measuring influence by
 connecting multiple
You	
  are	
  your	
  DNA	
  




                         genotype	
  (G)	
  +	
  environment	
  (E)	
  →	
  phenotype	
  (P)	
  

genotype	
  (G)	
  +	
  environment	
  (E)	
  +	
  genotype	
  	
  environment	
  interac:ons	
  (GE)	
  →	
  phenotype	
  (P)	
  
Behavior	
  Has	
  a	
  Very	
  Significant	
  Gene:c	
  Component	
  
	
  




       • Monozygo2c	
  twins	
  reared	
  apart	
  clearly	
  demonstrate	
  
       gene2c	
  influence	
  on	
  personality,	
  temperament,	
  
       predisposi2on	
  for	
  anxiety,	
  OCD,	
  IQ	
  (70%	
  of	
  variance	
  is	
  
       gene2c),	
  occupa2onal	
  and	
  leisure-­‐2me	
  interests,	
  social	
  
       aMtudes,	
  vo2ng	
  behavior,	
  problem	
  solving,	
  drug	
  abuse,	
  
       alcohol	
  abuse,	
  adult	
  	
  childhood	
  an2social	
  behavior,	
  
       suicidal	
  behavior,	
  Au2sm	
  Spectrum	
  Disorders,	
  ADHD,	
  bed	
  
       weMng.	
  
       	
  
       • By	
  way	
  of	
  behavioral	
  gene2cs	
  a	
  person’s	
  par2cipa2on	
  in	
  
       social	
  media,	
  responsiveness	
  to	
  messaging,	
  early	
  
       adop2on,	
  brand	
  loyalty	
  are	
  likely	
  to	
  be	
  predictable	
  
Genotyping
•  Health	
  results	
  for	
  Annemarie	
  




      Disease risk and ancestry
Each	
  of	
  us	
  is	
  a	
  walking	
  clinical	
  trial	
  


                                   • Gene2cs	
  
                                   • Physique	
  
                                   • Lifestyle	
  
                       Phenome	
   • Consump2on	
  
                                   • Loca2on	
  
                                   • Rela2onships	
  
Clear marketing opportunities
Sequencing	
  costs	
  plumme:ng	
  



                                                      Oxford	
  Nanopore–	
  MinION	
  
                                                      	
  	
  




                                                     LIFE	
  Technology	
  –	
  Ion	
  Proton	
  

$1,000	
  genome	
  is	
  just	
  the	
  start	
  
Environmental	
  DNA	
  Sampling	
  
Henrietta Lacks (HeLa cells)
Consumption	

                                                                        Relationships	


                                                              Physique	

   Lifestyle	


                                                                            Location	

            Genetics	



Multiple data layers already mined	

            Scott Davies	

            http://www.flickr.com/photos/scottdavies/4641542362
I like this beer because...	

Garin Fons	

http://www.flickr.com/photos/mrgarin/3382527848/
Tim Murtaugh	




   Genetic target marketing	

                                                     http://www.flickr.com/photos/_tim/513637637/	





Phil Dragash	

http://www.flickr.com/photos/philman/2741811882/
6 billion base pairs =	

                                  6 gigabytes per DNA sequence	



        In the U.S. = 1,800 petabytes or roughly two exabytes	



             The data	

Robert Gaal	

http://www.flickr.com/photos/blueace/312036915/
High volume data analysis
Privacy controls
The risks
Solutions
•  Is	
  there	
  a	
  way	
  to	
  protect	
  the	
  privacy	
  of	
  your	
  gene2c	
  
     data?	
  (copyright	
  or	
  patents)	
  
	
  
•  Is	
  there	
  a	
  way	
  insure	
  that	
  gene2c	
  based	
  value	
  crea2on	
  
     is	
  directed	
  by	
  and	
  returned	
  to	
  the	
  owner	
  of	
  the	
  
     gene2c	
  data?	
  
	
  
Your	
  Genome	
  	
  Phenome	
  Belong	
  to	
  You	
  
We	
  predict	
  that	
  personal	
  gene:cs	
  will	
  be	
  
used	
  as	
  a	
  marke:ng	
  tool	
  
	
  
Someone	
  will	
  get	
  paid	
  
	
  
We	
  propose	
  a	
  gene:c	
  equity	
  trust	
  that	
  
enforces	
  ownership	
  
	
  
Opt-­‐in	
  for	
  sharing	
  with:	
  
	
  
•  Philanthropic	
  organiza:ons	
  
•  Pharmaceu:cal	
  companies	
  
•  Marke:ng	
  organiza:ons	
  

Some	
  marke:ng	
  opportuni:es	
  can	
  return	
  
dividends	
  to	
  gene:c	
  equity	
  holders	
  
Miinome	
  as	
  a	
  gene:c	
  equity	
  broker?	
  	
  
                         Opt-­‐In	
  NOT	
  Opt-­‐Out	
  
                         	
  
                         Control	
  Your	
  Own	
  Des:ny	
  
                         	
  
                         Invest	
  in	
  yourself	
  
                         	
  
                         Get	
  Paid	
  
                         	
  
                         •  Should	
  Miinome	
  be	
  a	
  Coop?	
  	
  
                           •  Like	
  a	
  credit	
  union?	
  
                         	
  
                         	
  
Is	
  this	
  the	
  Future?	
  

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Influence: It's in your genes DNA SXSW

  • 1. Jack Newton http://www.flickr.com/photos/jdn/5544977049/ Influence: It s in Your Genes How to own your genetic equity #DNAsxsw
  • 2. Paul Saarinen Scott Fahrenkrug, Yamamoto, Director of Digital Strategy PH.DUniversity of Minnesota, Partner, Zingstring.com Director of the Animal Biotechnology Center Founder, Recombinetics
  • 3. Demographic  and  psychographic  informa2on   Age,  marital  status,  kids,  home  loca2on,  es2mated  salary,    recently   moved,  credit  cards,  web  sites,  ethnicity,  job  history,  magazines,   bankruptcy,  divorce,  year  you  bought  (or  lost)  your  house,  college,  online   discussion  topics,  brands  of  coffee,  paper  towels,  cereal  or  applesauce,   poli2cal  leanings,  reading  habits,  charitable  giving,  number  of  cars,   interests,  check-­‐ins,  groups,  and  friends.   All your data are belongs to us
  • 4. Mark Zuckerberg has said they can determine within a 33% accuracy when you ll break up and who you ll start dating Facebook relationship prediction
  • 5. Can predict with a 98% accuracy up to two years ahead of time if you’ll get a divorce Credit databases
  • 6. URSQUARE ict where you’ll go next based orical check-in’s and friends activities Wants to predict where you’ll go next Foursquare
  • 7. Measuring influence by connecting multiple
  • 8. You  are  your  DNA   genotype  (G)  +  environment  (E)  →  phenotype  (P)   genotype  (G)  +  environment  (E)  +  genotype    environment  interac:ons  (GE)  →  phenotype  (P)  
  • 9. Behavior  Has  a  Very  Significant  Gene:c  Component     • Monozygo2c  twins  reared  apart  clearly  demonstrate   gene2c  influence  on  personality,  temperament,   predisposi2on  for  anxiety,  OCD,  IQ  (70%  of  variance  is   gene2c),  occupa2onal  and  leisure-­‐2me  interests,  social   aMtudes,  vo2ng  behavior,  problem  solving,  drug  abuse,   alcohol  abuse,  adult    childhood  an2social  behavior,   suicidal  behavior,  Au2sm  Spectrum  Disorders,  ADHD,  bed   weMng.     • By  way  of  behavioral  gene2cs  a  person’s  par2cipa2on  in   social  media,  responsiveness  to  messaging,  early   adop2on,  brand  loyalty  are  likely  to  be  predictable  
  • 11.
  • 12. •  Health  results  for  Annemarie   Disease risk and ancestry
  • 13. Each  of  us  is  a  walking  clinical  trial   • Gene2cs   • Physique   • Lifestyle   Phenome   • Consump2on   • Loca2on   • Rela2onships  
  • 15. Sequencing  costs  plumme:ng   Oxford  Nanopore–  MinION       LIFE  Technology  –  Ion  Proton   $1,000  genome  is  just  the  start  
  • 18. Consumption Relationships Physique Lifestyle Location Genetics Multiple data layers already mined Scott Davies http://www.flickr.com/photos/scottdavies/4641542362
  • 19. I like this beer because... Garin Fons http://www.flickr.com/photos/mrgarin/3382527848/
  • 20. Tim Murtaugh Genetic target marketing http://www.flickr.com/photos/_tim/513637637/ Phil Dragash http://www.flickr.com/photos/philman/2741811882/
  • 21. 6 billion base pairs = 6 gigabytes per DNA sequence In the U.S. = 1,800 petabytes or roughly two exabytes The data Robert Gaal http://www.flickr.com/photos/blueace/312036915/
  • 22. High volume data analysis
  • 26. •  Is  there  a  way  to  protect  the  privacy  of  your  gene2c   data?  (copyright  or  patents)     •  Is  there  a  way  insure  that  gene2c  based  value  crea2on   is  directed  by  and  returned  to  the  owner  of  the   gene2c  data?    
  • 27. Your  Genome    Phenome  Belong  to  You   We  predict  that  personal  gene:cs  will  be   used  as  a  marke:ng  tool     Someone  will  get  paid     We  propose  a  gene:c  equity  trust  that   enforces  ownership     Opt-­‐in  for  sharing  with:     •  Philanthropic  organiza:ons   •  Pharmaceu:cal  companies   •  Marke:ng  organiza:ons   Some  marke:ng  opportuni:es  can  return   dividends  to  gene:c  equity  holders  
  • 28. Miinome  as  a  gene:c  equity  broker?     Opt-­‐In  NOT  Opt-­‐Out     Control  Your  Own  Des:ny     Invest  in  yourself     Get  Paid     •  Should  Miinome  be  a  Coop?     •  Like  a  credit  union?      
  • 29. Is  this  the  Future?