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AKI in ICUAKI in ICU
An OverviewAn Overview
By
Dr. Ahmed Mohammed Abd El Wahab
Lecturer of internal medicine(Nephrology)
Epidemiology
Up to 18% of hospitalized
patients with baseline normal
renal function experience AKI
Up to 4% of hospital
admissions are due to AKI
Mortality may reach up to 70%
in AKI requiring RRT
Why kidney is easily exposed to
Toxin and Drug
 Blood flow 1/3 of cardiac output
 High energy demand
 Water reabsorption, increase
concentration of toxic materials
 Tubular reabsorption and secretion
of some drugs
Risk Factors contd.,
Contd.,
Pathophysiology
Contd.,
Presentation
Detection
New markers
Contd.,
Management
Contd.,
Aki in icu

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Aki in icu