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HISTOLOGY OF UTERUS
PRESENTED BY RIYA SHARMA
Introduction to female reproductive organ
Introduction to Uterus
• Uterus is hollow muscular pear shaped
organ lies in the pelvic cavity between
urinary bladder and rectum
• It is about 7.5cm long ,5 cm wide and its
walls are about 2.5 cm thick and weighs
about 30 to 40 grams
Blood supply :
Arterial blood supply : uterine arteries
branches of internal iliac artery
ovaries :ovarian arteries
Venous blood supply : internal iliac veins
Introduction contd….
Nerve supply :parasympathetic
fibres from the sacral outflow and
sympathetic fibres form lumbar
out flow
HISTOLOGY OF UTERUS
≈thick wall made up of muscle
≈covered by peritoneum
≈ small lumen lined by mucus
membrane
Histology contd……..
• Wall of uterus has three layers ,they are
1.Peritoneum
2.Myometrium
3.Endometrium
1.perimetrium
• Typical serosa consisting single layer of
mesothelial cells supported by
connective tissue
• Folded on to the upper part of urinary
bladder called vesicounter pouch
PERITONEUM CONTD….
• Folds on rectum called rectouterine
pouch
• Laterally it form double fold with uterine
tubes ,cover fundus only called as broad
ligament
Myometrium
• Massive coat of smooth muscle arranged
In bundle ,separated by connective tissue
• 3 layers
• A inner layers of longitudinal muscle
fibres : the startum subvasculare
• A thick middle layer of cirucular and
obligue muscle fibres :stratum vasculare
MYOMETRIUM CONTD….
• An outer thin longitudinal layer beanth
perimetrium :startum supravascular
• The muscle cells have great elongation power
• Contraction of the muscle responsible for
expulsion of the fetus at the time of chlid birth
3.ENDOMETRIUM
• Mucus membrane of the uterus
• Columnar epithelium containing mucus
secreting tubular gland
• Consists of lamina propria
• Blood vessel and stroma also under go
cyclic changes
ENDOMETRIUM CONTD..
• Has two layers
1.Upper functional layer thicker and reach in
blood vessel ,shed of during mestruation
2.basal layer lies next to myometrium ,fresh
functional layer generated during each cycle
ENDOMETRIUM CONTD……
 Lining epithelium before menarche are
ciliated
Epithelium rest on stroma ,highly cellular,
vascular & contain glands lined with
columnar epithelium
• Menstrual phases: postmenstrual
(thin),proliferative ,secretory(thickest) and
mestrual
CERVIX
• Cervix is somewhat different than body
of uterus
• Mucus membrane has number of oblique
fold called palmate folds
• Mucosa show small glandular cyst called
as ovula nabothi
CERVIX CONTD…..
• Mucus membrane lined with ciliated and
non ciliated epithelium
• Near the external os lined with startified
squamous epithelium
• Stroma under lying epithelium is less
cellular than body
CERVIX CONTD…..
• Narrow lumen with tremendous capacity of
dilation during child birth
Histology of uterus and  cervix

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Histology of uterus and cervix

  • 2. Introduction to female reproductive organ
  • 3.
  • 4. Introduction to Uterus • Uterus is hollow muscular pear shaped organ lies in the pelvic cavity between urinary bladder and rectum • It is about 7.5cm long ,5 cm wide and its walls are about 2.5 cm thick and weighs about 30 to 40 grams
  • 5. Blood supply : Arterial blood supply : uterine arteries branches of internal iliac artery ovaries :ovarian arteries Venous blood supply : internal iliac veins Introduction contd….
  • 6. Nerve supply :parasympathetic fibres from the sacral outflow and sympathetic fibres form lumbar out flow
  • 7. HISTOLOGY OF UTERUS ≈thick wall made up of muscle ≈covered by peritoneum ≈ small lumen lined by mucus membrane
  • 8. Histology contd…….. • Wall of uterus has three layers ,they are 1.Peritoneum 2.Myometrium 3.Endometrium
  • 9.
  • 10. 1.perimetrium • Typical serosa consisting single layer of mesothelial cells supported by connective tissue • Folded on to the upper part of urinary bladder called vesicounter pouch
  • 11. PERITONEUM CONTD…. • Folds on rectum called rectouterine pouch • Laterally it form double fold with uterine tubes ,cover fundus only called as broad ligament
  • 12. Myometrium • Massive coat of smooth muscle arranged In bundle ,separated by connective tissue • 3 layers • A inner layers of longitudinal muscle fibres : the startum subvasculare • A thick middle layer of cirucular and obligue muscle fibres :stratum vasculare
  • 13. MYOMETRIUM CONTD…. • An outer thin longitudinal layer beanth perimetrium :startum supravascular • The muscle cells have great elongation power • Contraction of the muscle responsible for expulsion of the fetus at the time of chlid birth
  • 14. 3.ENDOMETRIUM • Mucus membrane of the uterus • Columnar epithelium containing mucus secreting tubular gland • Consists of lamina propria • Blood vessel and stroma also under go cyclic changes
  • 15. ENDOMETRIUM CONTD.. • Has two layers 1.Upper functional layer thicker and reach in blood vessel ,shed of during mestruation 2.basal layer lies next to myometrium ,fresh functional layer generated during each cycle
  • 16. ENDOMETRIUM CONTD……  Lining epithelium before menarche are ciliated Epithelium rest on stroma ,highly cellular, vascular & contain glands lined with columnar epithelium • Menstrual phases: postmenstrual (thin),proliferative ,secretory(thickest) and mestrual
  • 17.
  • 18. CERVIX • Cervix is somewhat different than body of uterus • Mucus membrane has number of oblique fold called palmate folds • Mucosa show small glandular cyst called as ovula nabothi
  • 19. CERVIX CONTD….. • Mucus membrane lined with ciliated and non ciliated epithelium • Near the external os lined with startified squamous epithelium • Stroma under lying epithelium is less cellular than body
  • 20. CERVIX CONTD….. • Narrow lumen with tremendous capacity of dilation during child birth