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OVERVIEW
• Definitions – Lump , Swelling and Tumor
• Differences Between Benign And Malignant
  Swellings

• Evaluation of a swelling – History
• Evaluation of a swelling – Physical Examination

• Benign Skin Swellings
• Congenital
• Inflammatory
• Traumatic
•   Miscellaneous
• Neoplastic

•   Special Investigations and Treatment Options
Lump: vague mass of body
tissue
Swelling: enlargement or protuberance in the
body due to any cause. A swelling may
be: - Congenital
    -Traumatic
   - Infalmmatory
   - Neoplastic
   -Miscellaneous
Tumor: growth of new cells which proliferate
independently.
  - Benign tumour proliferates slowly with little
evidence of mitoses and invasiveness
- Malignant tumour proliferates fast with
invasiveness and mitosis.
Benign
    Occurs at a younger age        Malignant
                              Usually seen above 40 years
                              or might occur at a younger
                              age
Duration: Slow growth         Duration:     Rapid
                              growth
Pain: Usually absent          Pain: May be painful

Loss of weight: Never         Loss of weight: Present
seen

Loss of function: Not seen Loss of function: Seen
                           quite early
Mobility: Freely mobile                   Mobility: Fixed due to infiltration



Surface: Usually smooth                   Surface: Usually irregular
Margin: Definite and smooth               Margin: Not definite and irregular


Consistency: Usually firm                 Consistency: Hard or varying
Pressure effects: Absent                  Pressure affect: Present
Lymph nodes: Not enlarged                 Lymph nodes: Enlarged
Distant metastasis: Not seen              Distant metastasis: Seen in late stage.


Recurrence: Never recurs after excision   Recurrence: Often recurs after excision


Secndary changes: Not seen                Secondary changes: Often present
History

1. Duration
2. Mode of onset
3. Associated symptoms
4. Progress of the swelling
5. Exact site
6. Fever
7. Presence of other lumps
8. Secondary changes
9. Impairment of function
10.Recurrence of the swelling
11.Loss of body weight

Past history
Personal history
Family history
General Examination

Local examination:

Inspection:

Situation- Few swellings are peculiar in their positions
Colour
Shape
Size
Surface
Edge
Number
Pulsation
Peristalsis
Movement with respiration
Impulse on coughing
Movement on deglutition
Movement with protrusion of the tongue
Skin over the swelling
Any pressure effect
Palpation

• Important part of local examination – collaborate findings of inspection and
  explore other findings

• BE GENTLE

• Temperature – MUST BE DONE FIRST !!!
• Tenderness – Look at facial expression , be gentle

• Size, shape and extent : try to find whole extent of swelling
• Surface – smooth (cyst) , lobular (lipoma) , nodular(matted
  lymph nodes), irregular and rough (carcinoma)

• Edge – well defined or indistinct, elicit SLIP SIGN
• Consistency – uniform or variable  uniform ( soft – lipoma,
  cystic – cyst, firm – fibroma, hard, but yielding – chondroma,
  bony hard – osteoma, stony hard – carcinoma)
• Consistency – In gaseous swellings ( gas gangrene, surgical
  emphysema) ; crepitus may be heard
• Variable consistency – carcinoma or sarcoma

• Also check – if swelling getting moulded to pressure –( ex:
  sebaceous cyst , dermoid cyst ) or pitting on pressure ( indicates
  edema – inflammatory swellings )
    •    FLUCTUATION TEST - swelling fluctuates when containing gas or
        liquid

    • Mechanism
    • Always perform in two planes

    • How to do fluctuation for 1. freely movable , 2. Very small
       (Pagets test)
    3. Very large swelling
       REMEMBER FALSE POSITIVE FLUCTUATION!!!
• FLUID THRILL – swellings containing fluid
• mechanism – Percussion wave is conducted to the other pole
  when one pole is tapped

• - Fluid thrill in small swelling ? Large swelling ?

• TRANSLUCENCY- Swelling containing clear fluid (even highly
  refractile fat) transmits light
• A swelling may be fluctuant BUT NOT translucent ( sebaceous
  cyst – pultaceous material )

• How to elicit ?

• COUGH IMPULSE – Swellings which are In communication with
  the abdominal ( eg hernia), pleural or spinal or cranial cavity

• Mechanism and how to elicit?
• In children  it is performed when they CRY
•   REDUCIBILITY – Hernia ( also lymph, varix, meningocele may
    reduce partly or completely

• Swelling reduces and ULTIMATELY DISAPPEARS WHEN PRESSED
  UPON.

• COMPRESSIBILITY – Swellings donot usually have
  communication with abdominal ,pleural or other cavities

• Liquid filled , usually from vascular malformations like capillary
  or cavernous hemangiomas.

• Contents reappear when pressure is taken off

• PULSATILITY – Maybe expansile ( arising from an artery) or
  transmitted ( near an artery )
• - How to differentiate ??
•   FIXITY TO THE OVERLYING SKIN : Swellings which originate from
    skin will move with skin ( except malignancies )

• Other swellings – how to know attachment to overlying skin?

• RELATIONS TO THE SURROUNDING STRUCTURES

• Swelling arising from subcutaneous tissue – free from overlying
  skin and underlying contracted muscle ( can be freely moved )

• Arising from deep fascia – Not be mobile as the one arising
  from S/C tissue

• Arising from muscle – it will be mobile when muscle is relaxed
• Ask patient to contract muscle – if swelling ARISES from muscle it will
  diminish in size , if it is arising from S/C tissue but attached to muscle , it will
  become more prominent and cannot be moved along line of muscle fibres..if
  it arises deep to the muscle, virtually disappear
State of the regional lymph nodes

Percussion: Not much of importance in case of a
swelling. Its sole place is to find out the presence
of gaseous content within the swelling. Ex.
Resonant note in hernia

Ascultation: All pulsatile swellings should be
ascultated to exclude presence of any bruits or
murmurs

Measurement

Movement- In case of a swelling you must
examine the movements of the nearby join to
exclude any impairment.
Examination for pressure effect: swellings may inevitably exert
pressure on the surrounding structures:

1. Arterial pulse distal to the swelling is felt. Sometimes the swelling
   may press on the main artery of the limb and cause weak pulse
   distally.

2. The nerves may be affected by the pressure of the swelling. This will
   cause wasting, paresis or paralysis of the muscles supplied by the
   nerve.

3. The swelling may exert pressure on the subjacent bone by eroding it.
   Example: Dermoid cyst on the skull
NEOPLASTIC
                                                     -   Lipoma
                 INFLAMMATORY                        -   Fibroma
                                                     -   Papilloma
                                 TRAUMATIC
             -   ABSCESS                             -   Neurofibroma
             -   BOIL, CARBUNCLE                     -   Lymphangioma
             -   Erysipelas                          -    Moles
             -   Cellulitis
CONGENITAL                                   MISCELLANEOUS
                                      - Sebaceous cyst
                                      - Warts
- DERMOID CYST                        - Condyloma
- HEMANGIOMAS
• Cyst lined by squamous epithelium – containing desquamated
  cells

• CONTENTS – mixture of sebum , sweat , desquamated epithelial
  cells, hair
                   • COMMON SITES OF OCCURRENCE




• Outer angle of
  orbit
                                                  • Sub-lingual
                     • Post – auricular dermoid
• Painless, slow
                                   •   Margins yield to the
  growing
                                       pressure of finger –
• Round , putty
                                       DOES NOT SLIP AWAY
• Free from skin and
  deeper structures
                                     -- > Differentiates
• Soft , cystic
                                   from lipoma
•   Fluctuation Positive
•   Translucency
    negative
                           • TYPES – Implantation or acquired
                             dermoid
                           • Tubulo dermoid
                           • Teratomatous dermoid
Plexiform
                                                 hemangioma
 • Capillary hemangioma • Cavernous hemangioma




                         Spider Nevus       Campbell de
Port – Wine stain                           Morgan Spots



                                            Strawberry
        Salmon Patch                        angioma
•   Capillary hemangioma   •   Cavernous hemangioma

• Usually flat             • Soft , spongy
• Bright red or purple     • Bluish swelling
  patches
                           • Blanches on
• Blanches on                pressure
  pressure                 • Compressible

•   Plexiform hemangioma


• Network of
  interwoven dilated
  arteries

• Bag of earthworms
Acute Inflammatory                           Chronic Inflammatory

 All signs of acute inflammation – rubor ,   All signs are present BUT SUBDUED
calor, dolor, tumor and functio lesia
Pain , redness and heat predominate          Swelling is more predominate
 Brawny induration and edema                 Brawny induration and edema ABSENT
conspicuously PRESENT

• Some sarcomas like                               Tenderness , Brawny induration
  osteosarcoma MIMICS                              and edema
  acute inflammatory
                                                   Fluctuation – ( pus )
  swelling with pain ,
  redness, swelling and
                                                   Acute lymphadenitis of related
  heat . How to                                    lymph nodes
  differentiate ??
                                                   Leucocytosis
• Chronic inflammatory                 Occasional dimunition in the size
  swellings may sometimes              of the swelling ( tumor never
                                       recedes )
  mimic malignancy . How
  to differentiate ??




- Localized accumulation of PMNL
  with tissue necrosis in the dermis
  and Subcutaneous tissue

-   Commonest organism –
    Staphylococcus aureus
- CLINICAL FEATURES

- Erythematous swelling, tenderness ,
  pain
- Pus draining from it
- Erythematous surroundings

-    May / may not be fluctuant ( parotid
    abscess is not fluctuant )


     THREE MAIN TYPES :

     - Pyogenic Abscess
     - Pyaemic abscess
     - Cold abscess
Pyogenic                Pyaemic                  Cold
                      (most common )

-Source of infection Cellulitis or acute       infective emboli –       Sequel to
                     lymphadenitis            lodge in different       TUEBRCULAR
                                              places -- MULTIPLE       INFECTION of lymph
                                              ABSCESSES                nodes and bone

- Clinical features    - red hot and tender   - commonly occur in      - NON-REACTING (
                       - pus  pain           SUBFASCIAL PLANE         NOT hot or painful )
                      becomes THROBBING
                      - Brawny induration     - Acute features I,e     - Caused by the
                          and EDEMA (           redness etc.           caseation of lymph
                          pitting)              ABSENT                 nodes

                      - Fluctuation +/-       -    Constitutional
                        (parotid)                 symptoms like high
                                                  fever, rigor etc.

Common sites           anywhere (eg.liver)     in the SUBFASCIAL        Neck and axilla
                                              plane ; multiple arise   May originate from
                                              when one has been        ends of bones  coe
                                              incised                  to surface through
                                                                       fascial planes
- Infection of hair follicle by Staphylococcus aureus
- Clinical Features

-    Starts as PAINFUL and INDURATED SWELLING
-    TENDERNESS and EDEMA +++
-    After some days  softening at the centre - PUSTULE  rupture spontaneously
     discharge GREEN

-       Then, DEEP CAVITY  lined by granulation tissue  heals by itself

-   COMMON SITES – Back and the neck
-   Complications ???


    -    Bigger ; same causative organism ; common in males >40 and DIABETICS

    -    Starts similar fashion to boil – spreads rapidly  progress similar to boil

    -    PATHOGNOMONIC FEATURE – Sieve like or cribriform appearance

    -    Multiple openings coalesce  ULCER with ashy-grey slough base  slough separates
          granulation tissue
Erysipelas                               Cellulitis ( MORE FATAL)
- Spreading cuticular lymphangitis               - Spreading inflammation of Subcutaneous
                                                tissue and fascia


- Organism – Str. Pyogenes                      Str. Pyogenes
- Predisposing factors – debilitation or poor    DIABETICS or debilitated state
health

- Features – RAISED RASH HAS SHARPLY            No DEFINITE EDGE
DEFINED MARGIN

Starts as rosy-red rash – disappears on          redness, itching and stiffness at site of
pressure                                        innoculation ;

                                                Red streaks (lymphangitis)  acute
                                                lymphadenitis or regional nodes

 Vescicles contain SEROUS FLUID                 Vescicles contain PUS
Traumatic:

Traumatic swellings arising from the skin and
subcutaneous tissue are rare. Hematoma following a
trauma may give rise to swelling.
Sebaceous Cyst:

- cyst of the sebaceous gland due to blockage of the duct of this gland
  which opens intp the hair follicle. The gland becomes distended by
  its own secretions.
- Contains sebum and always has a black spot on the swelling, which
  is the obstructed opening known as, “punctum”.

- Common in scalp, face, scrotum
- Single or multiple
- Smooth and round shape whose margin yields to the palpating
  finger
- Fluctuation test is positive
- Transillumination test is negative
Condyloma:
   - Hypertrophy of the epidermis
     occurring at the mucocutaneous
     junction ex. angle of the mouth,
     anus, vulva etc.

   - Fungating, sessile raised but flat
     growth with moist and sodden
     surface.

Warts: patches of overgrown skin
with hyperkeratosis

- Found in hands, face, knees, sole of
  the feet, axilla
- Firm and covered with rough
  surface and filiform excrescences
- Painful when they are repeatedly
  rubbed or become infected
- LIPOMA ( UNIVERSAL TUMOR ) – Commonest tumor of the
  subcutaneous tissue
- Benign tumor of the adipocytes

-




                            COMMON SITES

-
Other places – Intermuscular, Subfascial , Submucosal , Intra-
articular etc.
VARITIES OF LIPOMA – ENCAPSULATED , DIFFUSE and MULTIPLE
                                                          - Skin overlying –
                      Slowly growing and PAINLESS
                                                            usually normal
                      Can occur at any age – RARE IN
                                                          But in LARGE  Skin
                      CHILDREN
                                                          may be stretched

                                                          - Freely mobile over
                                                          deeper structures
Usually SMALL , may
attain large sizes
                                                          - Skin can be pinched
                                                          up

                         SOFT and LOBULATED consistency
- DIFFUSE LIPOMA - Does not possess features of lipoma – PSEUDOLIPOMA
- Subcutaneous and Intermuscular tissue of neck – extending into cheek

- NO CAPSULE
- Seen in Persons taking EXCESSIVE ALCOHOL

-     MULTIPLE LIPOMAS - Called LIPOMATOSIS
-     Painful often contain NERVE TISSUE ( NEUROLIPOMATOSIS )

-     Seen in limbs and Trunk
                                       - COMPLICATIONS

    - DECRUMS DISEASE                  -   Myxomatous degeneration
    - ( Adiposis Dolorosa )            -   Saponification
      – Tender lipomatous              -   Calcification
      swellings                        -   Infection
    - Seen in TRUNK                    -   Ulceration
    - Affects Women                    -   MALIGNANT CHANGE

                                       - Complications mainly – S/c tissue of
                                         thigh, buttock and Retroperitoneal
                                         tissue
Pedunculated with
                                                             Central fibrovascular
Overgrowth of all layers of         branched villous
                                                             core lined by epithelium
skin                                processes
                                                  - Sometimes, surface may be hard
   -       Swelling
                                                    – HORNY PAPILLOMA
   -       Papilliferous, pedunculated or sessile
   -       Usually Soft and solid                 - Complications- ulceration ,
   -       Moves with the SKIN                      bleeding , malignacy


       -   Other sites  lip, tongue, colon , rectum, kidney etc.
- Tumor of the fibrous tissue

                           -     True fibroma rarely occurs ; mostly combined with
                                 mesodermal tissues – Fibrolipoma, fibromyoma,
                                 neurofibroma etc.

-   Painless, Firm , WELL CIRCUMSCRIBED
-   Freely mobile on underlying structures
-   According to consistency maybe SOFT or FIRM ( usually FIRM )
    depending on amount of fibrous tissue

                       - DESMOID TUMOR ( Paget’s
                         recurrent fibroid)

                       -       Unusual
                       -       Arises in rectus sheath
                       -       Recurrence
                       -       Potential for malignancy
Lymphangioma: localized cluster of dilated lymh
sacs in the skin and subcutaneous tissues which
cannot connect into the normal lymph system.

3 types: a) Simple or capillary
             b) Cavernous
             c) Cytic hygroma

Simple or capillary:

- Presents as small vesicle or blister
- Present on the inner side of thigh, buttock,
  axilla
- 0.5-4mm in diameter
- Lesion is soft and spongy
- Multiple cysts or one or two large cysts
- Fluctuation, fluid thrill and translucency are
  positive
- Swelling is not compressible
- Lymph nodes are not enlarged
- Margin of the swelling is indistinct.
Cavernous :

- Present as bigger lymphatic swellings which are
   situated deep.
- Commonly occurs on the face, mouth, lips, axilla
- Lesion is soft and lobulated
- Single or multiple communicating lymphatic
   cysts
- Fluctuation and translucency positive
Cystic Hygroma:

- Common form of lymphangioma
- Collection of lymphatic sacs
- Large cyst like cavities containing clear
  watery fluid
- Found in axilla, mediastinum, groin,
  pelvis
- Soft swelling, compressible
- Fluctuation and translucency test are
  positive
- No lymph node enlargment
Neurofibromma: tumour contains both neural and fibrous
elements.

Local neurofibromma:

- Occur at any age but commonly seen in adults
- Present in subcutaneous tissue
- Firm, smooth swelling, slightly painful
- Cannot be moved in the direction of the nerve from
  which it arises
- Parasthesia and tingle sensation is common

Generalized neurofibrmatosis

- Involve the cranial spinal and peripheral nerves
- Multiple nodules present all over the body
- Found in subcutaneous tissue and can become
  pedunculated
- Nodules vary from being firm to soft
Plexiform Neurofibromatosis:

- Occurs in connection with the
  branches of the 5th cranial nerve
- Enormous swelling which hangs down
  and folds
- Mostly affects upper limb and may be
  associated with generalized
  neurofibromatosis

Elephentiasis Neurofibromatosis
- Affected skin becomes coarse, dry
   thick and resembles an elephant’s
   skin
- Subcutaneous tissue is replaced by
   fibrous tissue which is thick and
   oedematous
Moles: contain excess quantity of melanin derived
from melanocytes

Hairy mole:
- Flat and slightly raised above the level of skin
- Smooth or slightly warty epidermal covering
- Hair grow from its surface

Smooth mole:
- Surface is not elevated
- Epithelium is smooth and there is no hair growth
- Pigment is deeper

Blue naevus
- Occurs deep in the dermis as the thick overlying
   layers of the dermis and epidermis mask the
   colour of the melanin and make it look blue.
- Overlying skin is smooth and shiny
- Commonly seen on face, feet, buttock of children
Junctional naevus: clusters of cells of various
stages of maturity in the epidermis and dermis
when the growth and movements of melanocytes
stop before they have migrated into the dermis.

- Centered around the junctional or basal layer of
the epidermis
- immature, unstable and can turn malignant
- Smooth or elevated naevus of all shades
- Found in the palms, soles, digits, genetalia

Compound Naevus
- Two distinct varieties of mole are present-
  intradermal and junctional

Freckle
- Area of dark pigmentation found on face and
   neck
- Smooth surface however there might be
   junctional activity and may turn malignant
-   Routine – Blood, Urine, Aspiration

-   Fine Needle Aspiration Biopsy / Cytology – To avoid extensive open biopsy 
    Fine needle (22 or 23 gauge ) fitted with a tight syringe  tissue aspirated is
    examined microscopically, chemically and bacteriologically

-   X –ray : Mainly to check for erosions by a cyst ( eX dermoid cyst)
-   Ultrasound –
-   CT scan
-   MRI
-   Angiography

-  BIOPSY – Most important investigation of swelling ( suspected malignant
  tumors)
- NEEDLE BIOPSY
- DRILL BIOPSY (done for breast masses)
- PUNCH BIOPSY ( mainly for hollow viscus – tissue taken from margin of
  tumor along with surrounding normal tissue

-   OPEN BIOPSY  Incisional or excisional

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Benign Skin Swellings

  • 1.
  • 2. OVERVIEW • Definitions – Lump , Swelling and Tumor • Differences Between Benign And Malignant Swellings • Evaluation of a swelling – History • Evaluation of a swelling – Physical Examination • Benign Skin Swellings • Congenital • Inflammatory • Traumatic • Miscellaneous • Neoplastic • Special Investigations and Treatment Options
  • 3. Lump: vague mass of body tissue
  • 4. Swelling: enlargement or protuberance in the body due to any cause. A swelling may be: - Congenital -Traumatic - Infalmmatory - Neoplastic -Miscellaneous
  • 5. Tumor: growth of new cells which proliferate independently. - Benign tumour proliferates slowly with little evidence of mitoses and invasiveness - Malignant tumour proliferates fast with invasiveness and mitosis.
  • 6. Benign Occurs at a younger age Malignant Usually seen above 40 years or might occur at a younger age Duration: Slow growth Duration: Rapid growth Pain: Usually absent Pain: May be painful Loss of weight: Never Loss of weight: Present seen Loss of function: Not seen Loss of function: Seen quite early
  • 7. Mobility: Freely mobile Mobility: Fixed due to infiltration Surface: Usually smooth Surface: Usually irregular Margin: Definite and smooth Margin: Not definite and irregular Consistency: Usually firm Consistency: Hard or varying Pressure effects: Absent Pressure affect: Present Lymph nodes: Not enlarged Lymph nodes: Enlarged Distant metastasis: Not seen Distant metastasis: Seen in late stage. Recurrence: Never recurs after excision Recurrence: Often recurs after excision Secndary changes: Not seen Secondary changes: Often present
  • 8. History 1. Duration 2. Mode of onset 3. Associated symptoms 4. Progress of the swelling 5. Exact site 6. Fever 7. Presence of other lumps 8. Secondary changes 9. Impairment of function 10.Recurrence of the swelling 11.Loss of body weight Past history Personal history Family history
  • 9. General Examination Local examination: Inspection: Situation- Few swellings are peculiar in their positions Colour Shape Size Surface Edge Number Pulsation Peristalsis Movement with respiration Impulse on coughing Movement on deglutition Movement with protrusion of the tongue Skin over the swelling Any pressure effect
  • 10. Palpation • Important part of local examination – collaborate findings of inspection and explore other findings • BE GENTLE • Temperature – MUST BE DONE FIRST !!! • Tenderness – Look at facial expression , be gentle • Size, shape and extent : try to find whole extent of swelling • Surface – smooth (cyst) , lobular (lipoma) , nodular(matted lymph nodes), irregular and rough (carcinoma) • Edge – well defined or indistinct, elicit SLIP SIGN • Consistency – uniform or variable  uniform ( soft – lipoma, cystic – cyst, firm – fibroma, hard, but yielding – chondroma, bony hard – osteoma, stony hard – carcinoma)
  • 11. • Consistency – In gaseous swellings ( gas gangrene, surgical emphysema) ; crepitus may be heard • Variable consistency – carcinoma or sarcoma • Also check – if swelling getting moulded to pressure –( ex: sebaceous cyst , dermoid cyst ) or pitting on pressure ( indicates edema – inflammatory swellings ) • FLUCTUATION TEST - swelling fluctuates when containing gas or liquid • Mechanism • Always perform in two planes • How to do fluctuation for 1. freely movable , 2. Very small (Pagets test) 3. Very large swelling REMEMBER FALSE POSITIVE FLUCTUATION!!!
  • 12.
  • 13. • FLUID THRILL – swellings containing fluid • mechanism – Percussion wave is conducted to the other pole when one pole is tapped • - Fluid thrill in small swelling ? Large swelling ? • TRANSLUCENCY- Swelling containing clear fluid (even highly refractile fat) transmits light • A swelling may be fluctuant BUT NOT translucent ( sebaceous cyst – pultaceous material ) • How to elicit ? • COUGH IMPULSE – Swellings which are In communication with the abdominal ( eg hernia), pleural or spinal or cranial cavity • Mechanism and how to elicit? • In children  it is performed when they CRY
  • 14. • REDUCIBILITY – Hernia ( also lymph, varix, meningocele may reduce partly or completely • Swelling reduces and ULTIMATELY DISAPPEARS WHEN PRESSED UPON. • COMPRESSIBILITY – Swellings donot usually have communication with abdominal ,pleural or other cavities • Liquid filled , usually from vascular malformations like capillary or cavernous hemangiomas. • Contents reappear when pressure is taken off • PULSATILITY – Maybe expansile ( arising from an artery) or transmitted ( near an artery ) • - How to differentiate ??
  • 15. • FIXITY TO THE OVERLYING SKIN : Swellings which originate from skin will move with skin ( except malignancies ) • Other swellings – how to know attachment to overlying skin? • RELATIONS TO THE SURROUNDING STRUCTURES • Swelling arising from subcutaneous tissue – free from overlying skin and underlying contracted muscle ( can be freely moved ) • Arising from deep fascia – Not be mobile as the one arising from S/C tissue • Arising from muscle – it will be mobile when muscle is relaxed • Ask patient to contract muscle – if swelling ARISES from muscle it will diminish in size , if it is arising from S/C tissue but attached to muscle , it will become more prominent and cannot be moved along line of muscle fibres..if it arises deep to the muscle, virtually disappear
  • 16. State of the regional lymph nodes Percussion: Not much of importance in case of a swelling. Its sole place is to find out the presence of gaseous content within the swelling. Ex. Resonant note in hernia Ascultation: All pulsatile swellings should be ascultated to exclude presence of any bruits or murmurs Measurement Movement- In case of a swelling you must examine the movements of the nearby join to exclude any impairment.
  • 17. Examination for pressure effect: swellings may inevitably exert pressure on the surrounding structures: 1. Arterial pulse distal to the swelling is felt. Sometimes the swelling may press on the main artery of the limb and cause weak pulse distally. 2. The nerves may be affected by the pressure of the swelling. This will cause wasting, paresis or paralysis of the muscles supplied by the nerve. 3. The swelling may exert pressure on the subjacent bone by eroding it. Example: Dermoid cyst on the skull
  • 18. NEOPLASTIC - Lipoma INFLAMMATORY - Fibroma - Papilloma TRAUMATIC - ABSCESS - Neurofibroma - BOIL, CARBUNCLE - Lymphangioma - Erysipelas - Moles - Cellulitis CONGENITAL MISCELLANEOUS - Sebaceous cyst - Warts - DERMOID CYST - Condyloma - HEMANGIOMAS
  • 19. • Cyst lined by squamous epithelium – containing desquamated cells • CONTENTS – mixture of sebum , sweat , desquamated epithelial cells, hair • COMMON SITES OF OCCURRENCE • Outer angle of orbit • Sub-lingual • Post – auricular dermoid
  • 20. • Painless, slow • Margins yield to the growing pressure of finger – • Round , putty DOES NOT SLIP AWAY • Free from skin and deeper structures -- > Differentiates • Soft , cystic from lipoma • Fluctuation Positive • Translucency negative • TYPES – Implantation or acquired dermoid • Tubulo dermoid • Teratomatous dermoid
  • 21.
  • 22.
  • 23. Plexiform hemangioma • Capillary hemangioma • Cavernous hemangioma Spider Nevus Campbell de Port – Wine stain Morgan Spots Strawberry Salmon Patch angioma
  • 24. • Capillary hemangioma • Cavernous hemangioma • Usually flat • Soft , spongy • Bright red or purple • Bluish swelling patches • Blanches on • Blanches on pressure pressure • Compressible • Plexiform hemangioma • Network of interwoven dilated arteries • Bag of earthworms
  • 25. Acute Inflammatory Chronic Inflammatory All signs of acute inflammation – rubor , All signs are present BUT SUBDUED calor, dolor, tumor and functio lesia Pain , redness and heat predominate Swelling is more predominate Brawny induration and edema Brawny induration and edema ABSENT conspicuously PRESENT • Some sarcomas like Tenderness , Brawny induration osteosarcoma MIMICS and edema acute inflammatory Fluctuation – ( pus ) swelling with pain , redness, swelling and Acute lymphadenitis of related heat . How to lymph nodes differentiate ?? Leucocytosis
  • 26. • Chronic inflammatory Occasional dimunition in the size swellings may sometimes of the swelling ( tumor never recedes ) mimic malignancy . How to differentiate ?? - Localized accumulation of PMNL with tissue necrosis in the dermis and Subcutaneous tissue - Commonest organism – Staphylococcus aureus
  • 27. - CLINICAL FEATURES - Erythematous swelling, tenderness , pain - Pus draining from it - Erythematous surroundings - May / may not be fluctuant ( parotid abscess is not fluctuant ) THREE MAIN TYPES : - Pyogenic Abscess - Pyaemic abscess - Cold abscess
  • 28. Pyogenic Pyaemic Cold (most common ) -Source of infection Cellulitis or acute infective emboli – Sequel to lymphadenitis lodge in different TUEBRCULAR places -- MULTIPLE INFECTION of lymph ABSCESSES nodes and bone - Clinical features - red hot and tender - commonly occur in - NON-REACTING ( - pus  pain SUBFASCIAL PLANE NOT hot or painful ) becomes THROBBING - Brawny induration - Acute features I,e - Caused by the and EDEMA ( redness etc. caseation of lymph pitting) ABSENT nodes - Fluctuation +/- - Constitutional (parotid) symptoms like high fever, rigor etc. Common sites anywhere (eg.liver) in the SUBFASCIAL Neck and axilla plane ; multiple arise May originate from when one has been ends of bones  coe incised to surface through fascial planes
  • 29. - Infection of hair follicle by Staphylococcus aureus - Clinical Features - Starts as PAINFUL and INDURATED SWELLING - TENDERNESS and EDEMA +++ - After some days  softening at the centre - PUSTULE  rupture spontaneously  discharge GREEN - Then, DEEP CAVITY  lined by granulation tissue  heals by itself - COMMON SITES – Back and the neck - Complications ??? - Bigger ; same causative organism ; common in males >40 and DIABETICS - Starts similar fashion to boil – spreads rapidly  progress similar to boil - PATHOGNOMONIC FEATURE – Sieve like or cribriform appearance - Multiple openings coalesce  ULCER with ashy-grey slough base  slough separates  granulation tissue
  • 30. Erysipelas Cellulitis ( MORE FATAL) - Spreading cuticular lymphangitis - Spreading inflammation of Subcutaneous tissue and fascia - Organism – Str. Pyogenes Str. Pyogenes - Predisposing factors – debilitation or poor DIABETICS or debilitated state health - Features – RAISED RASH HAS SHARPLY No DEFINITE EDGE DEFINED MARGIN Starts as rosy-red rash – disappears on redness, itching and stiffness at site of pressure innoculation ; Red streaks (lymphangitis)  acute lymphadenitis or regional nodes Vescicles contain SEROUS FLUID Vescicles contain PUS
  • 31. Traumatic: Traumatic swellings arising from the skin and subcutaneous tissue are rare. Hematoma following a trauma may give rise to swelling.
  • 32. Sebaceous Cyst: - cyst of the sebaceous gland due to blockage of the duct of this gland which opens intp the hair follicle. The gland becomes distended by its own secretions. - Contains sebum and always has a black spot on the swelling, which is the obstructed opening known as, “punctum”. - Common in scalp, face, scrotum - Single or multiple - Smooth and round shape whose margin yields to the palpating finger - Fluctuation test is positive - Transillumination test is negative
  • 33. Condyloma: - Hypertrophy of the epidermis occurring at the mucocutaneous junction ex. angle of the mouth, anus, vulva etc. - Fungating, sessile raised but flat growth with moist and sodden surface. Warts: patches of overgrown skin with hyperkeratosis - Found in hands, face, knees, sole of the feet, axilla - Firm and covered with rough surface and filiform excrescences - Painful when they are repeatedly rubbed or become infected
  • 34. - LIPOMA ( UNIVERSAL TUMOR ) – Commonest tumor of the subcutaneous tissue - Benign tumor of the adipocytes - COMMON SITES - Other places – Intermuscular, Subfascial , Submucosal , Intra- articular etc.
  • 35. VARITIES OF LIPOMA – ENCAPSULATED , DIFFUSE and MULTIPLE - Skin overlying – Slowly growing and PAINLESS usually normal Can occur at any age – RARE IN But in LARGE  Skin CHILDREN may be stretched - Freely mobile over deeper structures Usually SMALL , may attain large sizes - Skin can be pinched up SOFT and LOBULATED consistency
  • 36.
  • 37. - DIFFUSE LIPOMA - Does not possess features of lipoma – PSEUDOLIPOMA - Subcutaneous and Intermuscular tissue of neck – extending into cheek - NO CAPSULE - Seen in Persons taking EXCESSIVE ALCOHOL - MULTIPLE LIPOMAS - Called LIPOMATOSIS - Painful often contain NERVE TISSUE ( NEUROLIPOMATOSIS ) - Seen in limbs and Trunk - COMPLICATIONS - DECRUMS DISEASE - Myxomatous degeneration - ( Adiposis Dolorosa ) - Saponification – Tender lipomatous - Calcification swellings - Infection - Seen in TRUNK - Ulceration - Affects Women - MALIGNANT CHANGE - Complications mainly – S/c tissue of thigh, buttock and Retroperitoneal tissue
  • 38.
  • 39. Pedunculated with Central fibrovascular Overgrowth of all layers of branched villous core lined by epithelium skin processes - Sometimes, surface may be hard - Swelling – HORNY PAPILLOMA - Papilliferous, pedunculated or sessile - Usually Soft and solid - Complications- ulceration , - Moves with the SKIN bleeding , malignacy - Other sites  lip, tongue, colon , rectum, kidney etc.
  • 40. - Tumor of the fibrous tissue - True fibroma rarely occurs ; mostly combined with mesodermal tissues – Fibrolipoma, fibromyoma, neurofibroma etc. - Painless, Firm , WELL CIRCUMSCRIBED - Freely mobile on underlying structures - According to consistency maybe SOFT or FIRM ( usually FIRM ) depending on amount of fibrous tissue - DESMOID TUMOR ( Paget’s recurrent fibroid) - Unusual - Arises in rectus sheath - Recurrence - Potential for malignancy
  • 41. Lymphangioma: localized cluster of dilated lymh sacs in the skin and subcutaneous tissues which cannot connect into the normal lymph system. 3 types: a) Simple or capillary b) Cavernous c) Cytic hygroma Simple or capillary: - Presents as small vesicle or blister - Present on the inner side of thigh, buttock, axilla - 0.5-4mm in diameter - Lesion is soft and spongy - Multiple cysts or one or two large cysts - Fluctuation, fluid thrill and translucency are positive - Swelling is not compressible - Lymph nodes are not enlarged - Margin of the swelling is indistinct.
  • 42. Cavernous : - Present as bigger lymphatic swellings which are situated deep. - Commonly occurs on the face, mouth, lips, axilla - Lesion is soft and lobulated - Single or multiple communicating lymphatic cysts - Fluctuation and translucency positive Cystic Hygroma: - Common form of lymphangioma - Collection of lymphatic sacs - Large cyst like cavities containing clear watery fluid - Found in axilla, mediastinum, groin, pelvis - Soft swelling, compressible - Fluctuation and translucency test are positive - No lymph node enlargment
  • 43. Neurofibromma: tumour contains both neural and fibrous elements. Local neurofibromma: - Occur at any age but commonly seen in adults - Present in subcutaneous tissue - Firm, smooth swelling, slightly painful - Cannot be moved in the direction of the nerve from which it arises - Parasthesia and tingle sensation is common Generalized neurofibrmatosis - Involve the cranial spinal and peripheral nerves - Multiple nodules present all over the body - Found in subcutaneous tissue and can become pedunculated - Nodules vary from being firm to soft
  • 44. Plexiform Neurofibromatosis: - Occurs in connection with the branches of the 5th cranial nerve - Enormous swelling which hangs down and folds - Mostly affects upper limb and may be associated with generalized neurofibromatosis Elephentiasis Neurofibromatosis - Affected skin becomes coarse, dry thick and resembles an elephant’s skin - Subcutaneous tissue is replaced by fibrous tissue which is thick and oedematous
  • 45. Moles: contain excess quantity of melanin derived from melanocytes Hairy mole: - Flat and slightly raised above the level of skin - Smooth or slightly warty epidermal covering - Hair grow from its surface Smooth mole: - Surface is not elevated - Epithelium is smooth and there is no hair growth - Pigment is deeper Blue naevus - Occurs deep in the dermis as the thick overlying layers of the dermis and epidermis mask the colour of the melanin and make it look blue. - Overlying skin is smooth and shiny - Commonly seen on face, feet, buttock of children
  • 46. Junctional naevus: clusters of cells of various stages of maturity in the epidermis and dermis when the growth and movements of melanocytes stop before they have migrated into the dermis. - Centered around the junctional or basal layer of the epidermis - immature, unstable and can turn malignant - Smooth or elevated naevus of all shades - Found in the palms, soles, digits, genetalia Compound Naevus - Two distinct varieties of mole are present- intradermal and junctional Freckle - Area of dark pigmentation found on face and neck - Smooth surface however there might be junctional activity and may turn malignant
  • 47. - Routine – Blood, Urine, Aspiration - Fine Needle Aspiration Biopsy / Cytology – To avoid extensive open biopsy  Fine needle (22 or 23 gauge ) fitted with a tight syringe  tissue aspirated is examined microscopically, chemically and bacteriologically - X –ray : Mainly to check for erosions by a cyst ( eX dermoid cyst) - Ultrasound – - CT scan - MRI - Angiography - BIOPSY – Most important investigation of swelling ( suspected malignant tumors) - NEEDLE BIOPSY - DRILL BIOPSY (done for breast masses) - PUNCH BIOPSY ( mainly for hollow viscus – tissue taken from margin of tumor along with surrounding normal tissue - OPEN BIOPSY  Incisional or excisional