Swine flu : The life threatening disease

1. Trt
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“Difficult to combat,
But not impossible”

2. ““A REVIEW ON SWINE FLU”A REVIEW ON SWINE FLU”
PRESENTED BY,PRESENTED BY,
SONALI DIWATE B.SONALI DIWATE B.
M.PHARMM.PHARM
(PHARMACOLOGY)(PHARMACOLOGY)
GUIDED BY,GUIDED BY,
PROF.CHANSHETTI R.PROF.CHANSHETTI R.
PE Society’s
Modern college of pharmacy (for ladies),
Moshi, Pune.
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3. AIMAIM
To review and study the Swine Flu.To review and study the Swine Flu.
OBJECTIVEOBJECTIVE
1.TO COLLECT THE INFORMATION ON SWINE FLU. (LITERATURE SURVEY).1.TO COLLECT THE INFORMATION ON SWINE FLU. (LITERATURE SURVEY).
2. TO SURVEY THE STATUS AND SEVERITY OF DISEASE ALL OVER THE WORLD.2. TO SURVEY THE STATUS AND SEVERITY OF DISEASE ALL OVER THE WORLD.
3. TO DESCRIBE EPIDEMIOLOGY OF DISEASE.3. TO DESCRIBE EPIDEMIOLOGY OF DISEASE.
4. TO STUDY LIFE CYCLE OF VIRUS.4. TO STUDY LIFE CYCLE OF VIRUS.
5. TO EXPLAIN PREVENTION AND TREATMENT OF SWINE FLU.5. TO EXPLAIN PREVENTION AND TREATMENT OF SWINE FLU.
6. TO INVESTIGATE RESEARCH SCOPE IN THIS AREA.6. TO INVESTIGATE RESEARCH SCOPE IN THIS AREA.
7. TO ANALYZE ALL THE PARAMETERS RELATED TO SWINE FLU.7. TO ANALYZE ALL THE PARAMETERS RELATED TO SWINE FLU.
8. TO AWARE PEOPLE ABOUT SWINE FLU.8. TO AWARE PEOPLE ABOUT SWINE FLU.
9.SUMMERIZATION OF THE INFORMATION AND WRITING OF PROJECT.9.SUMMERIZATION OF THE INFORMATION AND WRITING OF PROJECT. 2

4. CONTENTSCONTENTS…..…..
1. AIM AND OBJECTIVE1. AIM AND OBJECTIVE
2. INTRODUCTION2. INTRODUCTION
3. HISTORY OF SWINE FLU3. HISTORY OF SWINE FLU
4. STRUCTURE OF VIRUS4. STRUCTURE OF VIRUS
5. EPIDEMIOLOGY5. EPIDEMIOLOGY
6. SIGN AND SYMPTOMS6. SIGN AND SYMPTOMS
7. DIAGNOSTIC TESTS7. DIAGNOSTIC TESTS
8. TREATMENT8. TREATMENT
9. PREVENTION9. PREVENTION
10.CONCLUSION10.CONCLUSION
11.BIBLIOGRAPHY11.BIBLIOGRAPHY
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5. INTRODUCTIONINTRODUCTION[1]
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6. HISTORY OF VIRUSHISTORY OF VIRUS[2]
Year of Origin Sub-Type
1890 H2N8
1900 H3N8
1918 H1N1 (Spanish Flu)
1957 H2N2 (Asian Flu)
1968 H3N2 (Hong Kong Flu)
1977 HIN1 (Russian Flu)
2009 H1N1 (Swine Flu)
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Death Occurred…
1.RIDA SHAIKH (PUNE)
2.MR.FAHMIDA(MUMBAI)
3.MS.P.DIPIKA (PUNE)
Death Occurred…
1.RIDA SHAIKH (PUNE)
2.MR.FAHMIDA(MUMBAI)
3.MS.P.DIPIKA (PUNE)
ORIGIN =MEXICO.

7. ABOUT VIRUSABOUT VIRUS[3]
1] INFUENZA VIRUS A SUB TYPES- H1N11] INFUENZA VIRUS A SUB TYPES- H1N1
H1N2H1N2
H3N1H3N1
H2N3H2N3
2] SINGLE STRANDED RNA VIRUS .2] SINGLE STRANDED RNA VIRUS .
3] FAMILY - ORTHROMYXOVIRIDAE.3] FAMILY - ORTHROMYXOVIRIDAE.
4] SHAPE - SPHERICAL.4] SHAPE - SPHERICAL.
5] DIAMETER - 80-120nm.5] DIAMETER - 80-120nm.
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8. STRUCTURE OF VIRUSSTRUCTURE OF VIRUS[3]
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9. FORMATION OF SWINE FLU VIRUSFORMATION OF SWINE FLU VIRUS [4][4]
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10. EPIDEMIOLOGYEPIDEMIOLOGY[4]
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http://www.youtube.com/watch?v=c-36EiSejFU

11. 10
NORMALNORMAL
TRACHEALTRACHEAL
MUCOSAMUCOSA
3 DAYS3 DAYS
POST-POST-
INFECTIONINFECTION
7 DAYS7 DAYS
POST-POST-
INFECTIONINFECTION

12. SIGN AND SYMPTOMSSIGN AND SYMPTOMS[5]
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13. RUNNY NOSERUNNY NOSE
SORE THROATSORE THROAT
COUGHCOUGH
FEVERFEVER
BODY ACHEBODY ACHE
VOMITING & DIARRHOEAVOMITING & DIARRHOEA
DIFFICULTY IN BREATHINGDIFFICULTY IN BREATHING
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14. EMERGENCY WARNINGEMERGENCY WARNING
SIGNSSIGNS
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BREATHING DIFFICULTYBREATHING DIFFICULTY
PAIN IN CHESTPAIN IN CHEST
SUDDEN DIZZINESSUDDEN DIZZINES
CONFUSIONCONFUSION
SEVERE VOMITINGSEVERE VOMITING
HIGH FEVERHIGH FEVER
BLUISH SKIN COLOURBLUISH SKIN COLOUR

15. • Rapid antigen tests
• Immunofluorescent antibody
testing
• Real-time Reverse Transcriptase-
Polymerase Chain Reaction (RT-PCR)
• Collection of nose & throat swab
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DETECTION OF VIRUSDETECTION OF VIRUS [6][6]

16. TREATMENTTREATMENT[6,7]
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AYURVEDIC
OTHER
HOMEOPATHIC
ALLOPATHIC

17. ALLOPATHIC TREATMENTALLOPATHIC TREATMENT
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ORALLY
ADMINISTERED
DRUGS
VACCINES
M2 INHIBITORS
NEURAMINIDASE
INHIBITORS

18. NEURAMINIDASE INHIBITORSNEURAMINIDASE INHIBITORS
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ZANAMIVIRZANAMIVIR
OSELTAMIVIR
PO4

19. M2 INHIBITORSM2 INHIBITORS
AMANTIDINE
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REMANTIDINE

20. VACCINESVACCINES[8]
1] DEVELOPMENT OF VACCINE
STEP 1-IDENTIFICATION OF VIRUS
STEP 2-DEVELOPMENT OF PRIMARY SEED
STEP 3-TESTING
STEP 4-AUTHERIZATION
2]EXAMPLE-AREPANRIX,NASOVAC
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21. OTHER TREATMENTOTHER TREATMENT
IT INVOLVES,IT INVOLVES,
-PLENTY OF REST-PLENTY OF REST
-BE PHYSICALLY FIT-BE PHYSICALLY FIT
-EAT NUTRITIOUS FOOD-EAT NUTRITIOUS FOOD
-MANAGE YOUR STRESS-MANAGE YOUR STRESS
-DRINKING OF PLENTY OF WATER-DRINKING OF PLENTY OF WATER
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22. NEVER GIVE ASPIRIN TO CHILDRENS WHO HAVENEVER GIVE ASPIRIN TO CHILDRENS WHO HAVE
SWINEFLU BECAUSE IT MAY CAUSE REYE’S SYNDROME.SWINEFLU BECAUSE IT MAY CAUSE REYE’S SYNDROME.
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23. PREVENTIONPREVENTION[8]
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1.AVOID CLOSE CONTACT WITH PEOPLE
WHO APPEAR UNWELL AND HAVE FEVER
AND COUGH.
2.AVOID TOUCHING EYES, NOSE OR
MOUTH WITH UNWASHED HANDS.
3.WASH HANDS FREQUENTLY WITH SOAP
AND WATER.
4.AVOID TOUCHING SURFACES THAT
MAY BE CONTAMINATED WITH THE FLU
VIRUS.
5.REDUCE AS MUCH AS POSSIBLE THE
TIME SPENT IN CROWDED SETTINGS.
6.AVOID TRAVELLING N CROWDED
AREA
7.USE FACE MASK.

25. CONCLUSIONCONCLUSION
• The spread of infection has been facilitated by air and land travel and
social gatherings.
• The better understanding of routes of transmission, clinical features,
pathogenesis, and perhaps, response to treatment is required to check the spread of
infection.
• Detailed contact and travel histories and knowledge of viral activity in
community are essential for prompt case detection by the health personnel.
• Real-time RTPCR analysis of throat swabs or lower respiratory samples
may offer sensitive means of diagnosis.
• Use of oral Oseltamivir may be warranted for the treatment of severe
illness.
• Above all, there is an urgent need for global coordination in clinical and epidemiologic
research to control this outbreak.
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26. BIBLIOGRAPHYBIBLIOGRAPHY
1. Manish Sinha,; “Review on Swine flu, Journal of Infection and Public Health” Journal of Infection
and Public Health (2009) 2 p.g., 157—166.
2. Paul M.; “Origin of Human Virus Diversity”, Vol 108, feb8,2002, p.g. 305-312. &
Tokiko W.;” Pathogenesis of 1918 pandemic history of influenza virus”, Jan 2011, Vol 7 p.g. 1-5.
3. Rachalle S.; Robert G.; “The Influenza Virus Enginma”, Cell 136, Feb 6,2009. p.g. 402-410
4. www.protienlounge.com & www.direct.gov.uk/swine flu
5. John S., Anice C.; “ Transmission of Influenza virus in a mammalian host is increased by PB2
amino acid 627 and or 627 E/701N Jan 2,2009, Vol-5, p.g. 1-11.
6. http//www.swineflu-india.org.
7. www.homeopathy3fold.com
8. Tokiko W.;” Pathogenesis of 1918 pandemic history of influenza virus”, Jan 2011, Vol 7 p.g. 1-5.
9. Christian R. “The core protein of classical swine fever virus is dispensable for virus propagation
In Vitro”, Mar 2012, Vol 8, Issue 3, p.g. 1-13.
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27. Thank
You…..--------------------------------------------------------------------------------
Thank
You…..--------------------------------------------------------------------------------
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