Project Unity is a platform that will host all phenotype-to-genotype public-domain data in a common and unified platform, offered as a free service for academia. Each researcher will be able to load their data and connect it to existing global knowledge, by linking traits to ontology, markers to genetic/physical maps and germplasms to pedigree and their sources. Initially, each dataset is stored privately, and can only be accessed by the researcher comparing his results to public ones. Data is made public once the researcher decides to do so typically after the publication of the corresponding scientific paper.

1. Unleashing innovation through
next generation bio-informatics
Phenome Networks Confidential

2. 2
PLANT BREEDING COMPANIES GENERATE
ENDLESS DATA
It is stored in sub-optimal datastores such as
notes, excels and local solutions.
NO ONE HAS CONSOLIDATED ACCESS TO THE
SUM OF DATA FROM PUBLIC RESEARCH

3. A large financial investment goes to waste
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5,000
STUDIES
$100K
EACH
$500M
INVESTMENT

4. Phenome Networks Confidential
Impossible today
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Study
1
Study
2
Combined
insights
1+2

5. 5
What if we could standardize phenotype and
genotype vocabulary?
• Linking genomics to traditional breeding
• Share and compare data from multiple research groups
(standardization)
• Link to other academic public-domain data

6. Genetic research works to correlate
genotypes with phenotypes
POPULATION /ENVIRONMENT
POPULATION / ENVIRONMENT
POPULATION / ENVIRONMENT
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MILLIONS OF GENETIC MARKERS
One
study,
one
population
PHENOTYPES
Large investment
Vast amount of data
Complex analysis

7. Many research groups are working.
In isolation.
POPULATION /ENVIRONMENT
POPULATION / ENVIRONMENT
POPULATION / ENVIRONMENT
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MILLIONS OF GENETIC MARKERS
PHENOTYPES
One
study,
one
population

8. Sharing and collaboration among multiple
groups is challenging
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?
HIS
DATA
ADHOC
EXCEL
SHEET
PDF
REPORTS
MY
DATA

9. Missing crucial insights
POPULATION /ENVIRONMENT
POPULATION / ENVIRONMENT
POPULATION / ENVIRONMENT
population Other traits affected by my
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MILLIONS OF GENETIC MARKERS
PHENOTYPES
One
project,
one
favorite marker?
Impact of my markers in
other populations?
Are the effects consistent in
different environments?

10. Standardization is needed…
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Phenotype Germplasm Genotype
Trait 1
Trait 2
Trait 3
Trait’s
ontology
Unify
scales
Germplasm 1
Germplasm 2
Germplasm 3
Pedigree
relations
Define
source
Marker 1
Marker 2
Marker 3
Link to
genetic /
physical
map
Germplasm
Phenotype Genotype
Metadata on experiments / populations

11. In an ideal world we want to innovate by
integrating data from multiple sources
POPULATION /ENVIRONMENT
POPULATION / ENVIRONMENT
POPULATION / ENVIRONMENT
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MILLIONS OF GENETIC MARKERS
PHENOTYPES

12. Giving Private Access to Public Data
Private Public
1 2 3 4
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Register,
without
central
admins
Upload
data
Analyze
data
Integrate
with public
academic
data
Share data
and
findings
Search data
Search results
Correlate
Get alerts

13. UNITY: Aggregating all phenotypes / genotypes of
all species in one place
Papers Papers
Papers Papers
SGN GRAMENE NCBI PANZEA
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Papers
PHENOME-NETWORKS

14. UNITY: unleashing new insights by combining
information about the world’s species
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Study
1
Study
2
Combined
insights
1+2

15. Phenome Networks Confidential
We are in private beta.
For more information, go here:
http://phenome-networks.com/unity/
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