5. Diagram the feedback loop involved. 6. What is a palpable goiter, and would you expect to find a palpable goiter in this case? Explain your answer. A 30-year-old female demonstrated a subtle onset of the following symptoms: dull facial expression; droopy eyelids; puffiness of the face and periorbital swelling; sparse, dry hair; dry, scaly skin; evidence of intellectual impairment; lethargy; a change of personality; bradycardia (60b/min); a blood pressure of 90/70; constipation, and hypothermia. The patient does not complain of pain. Plasma concentrations of total and free T4 and T3 follow: A blood sample indicated elevated TSH levels. A TSH stimulation test did not increase the output of thyroid hormones from the thyroid gland. A biopsy of her thyroid revealed large numbers of lymphocytes in her thyroid gland..