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Female reproductive system1 copy
- 1. FEMALE REPRODUCTIVE SYSTEM OVARY FALLOPIAN TUBE VAGINA Prof.J.Anbalagan, anbuamu@rediffmail.com
- 3. OOGENESIS • OOGONIUM • PRIMARY OOCYTE – 44+XX • SECONDARY OOCYTE – 22+X, 1 POLAR BODY • MATURE OVUM – 22+X, 3 POLAR BODY Prof.J.Anbalagan
- 4. OVARY • Surrounded by simple cuboidal cells – Germinal epithelium • Deeper – Tunica albuginea Prof.J.Anbalagan
- 5. OVARY• Cortex – Ovarian follicles • at different stages of maturations – Stroma • with spindle shaped cells • Medulla – Loose connective tissue with elastic fibers – Blood vessels Prof.J.Anbalagan
- 6. Stages of maturation • Primordial follicle • Primary follicle • Secondary follicle • Antral follicle • Mature follicle (Graffian follicle) Prof.J.Anbalagan
- 7. PRIMORDIAL FOLLICLE • Primordial germ cells migrate from yolk sac • Arranged as primordial follicles • 5th IUL– 6 million primordial follicles • At birth- 2 million follicles • Puberty- 40,000 follicles • 400 follicles mature in reproductive cycle Prof.J.Anbalagan
- 8. Growth of ovarian follicles • PRIMARY FOLLICLES – Oocyte with prominent nucleus and nucleolus – Zona pellucida appears (glycoprotein) – Surrounded by cuboid/columnar granulose cells Zona pellucida Prof.J.Anbalagan
- 9. Secondary follicle • Increase in Oocyte size • Granulosa cells becomes multilayered • Surrounded by stromal cells- – Theca interna – Theca externa Prof.J.Anbalagan
- 10. Antral follicle • Appearance of spaces between granulosa cells • Fluid accumulation • Few cell adhere to ovum- – cumulus oophorus Prof.J.Anbalagan
- 11. Mature Graafian follicle • Fluid amount increases • Ovum pushed to one side • Surrounded by cumulus oophorus • External follicle surrounded by theca interna and theca externa • Increased intra follicular pressure • Follicle ruptures • Ovulation • Secondary oocyte in prophase stage Prof.J.Anbalagan
- 13. Corpus luteum • After ovulation • Follicular cells collapses • Invaded by blood vessels • Follicular cells become polyhedral • Accumulates lipid vacuoles, yellow pigments • Corpus luteum of menstruation- 10-12 days • Corpus luteum of pregnancy- 4 months • Corpus luteum albican- after involution Prof.J.Anbalagan
- 15. Atretic follicles • Number of follicles undergoes maturation • One succeeds • Remaining degenerates • Atretic stage occurs in all stages of maturation • Ovum dies and fibrous tissue grows into the follicle Prof.J.Anbalagan
- 17. FALLOPIAN TUBE • Mucous membrane thrown into folds • Each fold shows core of lamina propria • Folds shows primary, secondary and tertiary branches Prof.J.Anbalagan
- 18. • Lined by columnar epithelium • Ciliated • non ciliated cells (secretory) • Muscular layer-circular + longitudinal • Serosa – highly vascular Prof.J.Anbalagan
- 19. VAGINA • Tubular organ • Mucous • muscular layer • tunica adventitia • Connective tissue (elastic fibers) and blood vessels Prof.J.Anbalagan
- 20. VAGINA • Mucous membrane – Lamina propria-dense with elastic fibers, lymphatic nodules – Stratified squamous non keratinized epithelium – Superficial cells rich in glycogen • Sub mucosa with connective tissue and blood vessels • Intermingled longitudinal and circular muscle Prof.J.Anbalagan
- 24. VAGINA Stratified non keratinized Lamina propria Prof.J.Anbalagan
- 25. • Draw a labeled diagram showing the histological features of – Ovary – Fallopian tube • Name the coverings of ovary • Discuss the functions of corpus luteum • Discuss the different stages of ovarian follicle Prof.J.Anbalagan
- 26. Prof.J.Anbalagan