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Causes and Measures to alleviate it
      Dr. Kamlesh Lala MBBS
       Dr. Mrudula Lala MD
      Ahmedabad, INDIA
   kamleshlala@hotmail.com
           Dr. Kamlesh Lala/Dr. Mrudula lala   1
Dr. Kamlesh Lala/Dr. Mrudula lala   2
   Intramuscular Injection is the most widely
    practiced percutaneous procedure

   Each child is compulsorily exposed to this in
    his early childhood by way of immunisation

   The most common side effect is apprehension
    and pain


                 Dr. Kamlesh Lala/Dr. Mrudula lala   3
Pain is a subjective phenomenon influenced by
  multiple factors including
  Age
 Anxiety level

 Previous experience

 Ambience

 Approach of a provider

 Culture




                Dr. Kamlesh Lala/Dr. Mrudula lala   4
It is said that
     “Pain is inevitable”
              But
   “Suffering is optional”
But here we try to reduce this
            suffering

         Dr. Kamlesh Lala/Dr. Mrudula lala   5
 Concern and anxiety about
  injections are common for all
  ages.
 Several methods are found
  effective to relieve this
  apprehension and discomfort in
  different stages of injection
  procedure
           Dr. Kamlesh Lala/Dr. Mrudula lala   6
Dr. Kamlesh Lala/Dr. Mrudula lala   7
   Before Injection
   Drug
   Equipment
   Site Selection
   Pre Injection
   During Injection
   Post Injection



                  Dr. Kamlesh Lala/Dr. Mrudula lala   8
   Give age appropriate dose of NSAID. Avoid
    aspirin in children. Administer Paracetamol in
    dose of 15-20 mg/kg.
   Local Anaesthetic (5% Xylocaine) can be
    applied at the site of injection an hour before
   Administer sweet tasting liquid (2ml of 20%
    w/v sucrose or expressed breast milk)
    immediately before.
   Child can even be breast fed immediately
    before
                  Dr. Kamlesh Lala/Dr. Mrudula lala   9
   Shake Test for DTwP vaccine: Shake well the
    vaccine vial. After shaking, the vaccine
    sediment within 30 minutes leaving a deposit
    below a column of transparent fluid. This
    indicates that vaccine has been frozen in a cold
    chain. Discard such vial. Frozen vaccine
    increases the chances of local reaction and
    sterile abscess.



                  Dr. Kamlesh Lala/Dr. Mrudula lala    10
   Benzyl Alcohol (BA) is used to increase the
    lipid solubility of esterified compounds and to
    prevent bacteria growth. It can cause
    destruction of cells and localised pain and
    inflammation.
   After injection of the drug, BA is absorbed from
    the site causing active drug to precipitate fine
    crystals within the muscle. This causes pain
    after 4-12 hours of injection characterised by
    pain and inuration.

                  Dr. Kamlesh Lala/Dr. Mrudula lala   11
   Tissue irritation is the most common cause of
    Post Injection Pain. It starts 12-24 hours after
    injection with warm, red, tender induration.
    This will fade after 72 hours.
   Common with hormone injections.
   More common in a brand manufactured by
    local drug company. (poor quality of raw
    material, excessive preservative, too much BA
    used)


                  Dr. Kamlesh Lala/Dr. Mrudula lala    12
   Addition of Benzyl Benzoate (BB) can reduce it.
   Gently warm the oily injection by rubbing it in
    between two palms so as to improve the
    viscosity of the drug.
   Larger than 5 ml volume is not advised for
    intramuscular injection. It should be divided
    into multiple injection at different sites.




                  Dr. Kamlesh Lala/Dr. Mrudula lala   13
   Use new syringe and needle every time.
   Longer needle reduces redness and swelling,
    because medication is sure into the muscle.
    More so with Chloroquine and Diclofenac. So
    use 1.5” long needle for gluteal injection in
    adolescents and adults.
   Use wide bore needle eg. 23g because narrow
    bore produces a jet under pressure causing
    muscle injury and pain.
   For oily injection, use still wider bore needle
    (21g or 22g).
                  Dr. Kamlesh Lala/Dr. Mrudula lala   14
   Use anterolateral thigh in children up to 2
    years or even up to 5 years.
   After that use deltoid muscle
   In adults use gluteal muscle for oily injection or
    if volume is greater than 2 ml.
   Larger volumes are better tolerated in larger
    muscle groups

                   Dr. Kamlesh Lala/Dr. Mrudula lala   15
   Do not use the same site over and over again
    for days for multiple injections.

   It may cause irritation and muscle injury; and
    increases the chances of infection.

   Rotate the site.




                   Dr. Kamlesh Lala/Dr. Mrudula lala   16
   After swabbing the site with spirit or
    alcohol, allow it to dry, or it may cause
    irritation.
   Topical refrigerant (vapocoolant) spray
    immediately before the injection may reduce
    the short term pain.
   Do not keep the air bubble inside the syringe.
   Proper positioning of the patient allows to
    identify the site correctly.
   Ensures patient’s comfort by muscle relaxation.
                  Dr. Kamlesh Lala/Dr. Mrudula lala   17
   1. Standard technique
    The needle is introduced at 900 with steady
    pressure and aspiration to be performed for 5-
    10 seconds, drug is slowly injected over 5-10
    secs., and the needle to be withdrawn slowly
   2. Pragmatic technique
     The needle is introduced at 900 with steady
    pressure and no aspiration is to be
    performed, drug is rapidly injected over 1-2
    secs., and the needle to be withdrawn rapidly
                  Dr. Kamlesh Lala/Dr. Mrudula lala   18
In a randomised controlled trial to compare acute
  pain response during immunisation in infants
  using these two techniques, it was found that
  Pragmatic technique is less painful than a
  standard one.




                  Dr. Kamlesh Lala/Dr. Mrudula lala   19
Z track technique.
Skin is pulled downwards and laterally before
  injection. This displaces the skin and SC tissue
  leaving the muscle there only and uses the
  valve action to prevent leakage of medication
  into the SC tissue and later on irritation.




                 Dr. Kamlesh Lala/Dr. Mrudula lala   20
Dr. Kamlesh Lala/Dr. Mrudula lala   21
   Age appropriate non pharmacological
    techniques may provide distraction from pain.

   Some of the distraction techniques are age
    appropriate toys, playing music, pretending to
    blow away pain, watching TV, conversation
    with child, deep breathing etc.


                  Dr. Kamlesh Lala/Dr. Mrudula lala   22
Dr. Kamlesh Lala/Dr. Mrudula lala   23
   Tactile Stimulation
    Rubbing or stroking the skin near
    the injection site with moderate
    intensity may decrease the pain in
    older children and adults.

               Dr. Kamlesh Lala/Dr. Mrudula lala   24
   Aspiration can be performed in non immunisation
    injections, but should be fast.
   Ensure that the injection is deep into the muscle
    and fully through any subcutaneous fat. Injection
    into the fat may result in fat necrosis and abscess.
   In case of larger volume injection, inject the drug
    slowly so as to reduce muscle fascia displacement
    (which may result in pain and scarring of muscle)
   Withdraw the needle at the same angle as for
    penetration.

                    Dr. Kamlesh Lala/Dr. Mrudula lala      25
Dr. Kamlesh Lala/Dr. Mrudula lala   26
   Order of Injection
    For multiple injections, especially
    during immunisation, inject the
    most painful injection (DTP) last



               Dr. Kamlesh Lala/Dr. Mrudula lala   27
   Apply a little pressure to the injection site for 5-
    10 seconds.

   Do not massage or rub the site.

   Do not apply hot or cold compresses. Clean
    cold wet wash cloth can be applied over sore
    area.


                   Dr. Kamlesh Lala/Dr. Mrudula lala   28
Patient should leave the clinic laughing……and
  not crying….
                Dr. Kamlesh Lala/Dr. Mrudula lala   29

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Intramuscular injection pain ppt

  • 1. Causes and Measures to alleviate it Dr. Kamlesh Lala MBBS Dr. Mrudula Lala MD Ahmedabad, INDIA kamleshlala@hotmail.com Dr. Kamlesh Lala/Dr. Mrudula lala 1
  • 2. Dr. Kamlesh Lala/Dr. Mrudula lala 2
  • 3. Intramuscular Injection is the most widely practiced percutaneous procedure  Each child is compulsorily exposed to this in his early childhood by way of immunisation  The most common side effect is apprehension and pain Dr. Kamlesh Lala/Dr. Mrudula lala 3
  • 4. Pain is a subjective phenomenon influenced by multiple factors including  Age  Anxiety level  Previous experience  Ambience  Approach of a provider  Culture Dr. Kamlesh Lala/Dr. Mrudula lala 4
  • 5. It is said that “Pain is inevitable” But “Suffering is optional” But here we try to reduce this suffering Dr. Kamlesh Lala/Dr. Mrudula lala 5
  • 6.  Concern and anxiety about injections are common for all ages.  Several methods are found effective to relieve this apprehension and discomfort in different stages of injection procedure Dr. Kamlesh Lala/Dr. Mrudula lala 6
  • 7. Dr. Kamlesh Lala/Dr. Mrudula lala 7
  • 8. Before Injection  Drug  Equipment  Site Selection  Pre Injection  During Injection  Post Injection Dr. Kamlesh Lala/Dr. Mrudula lala 8
  • 9. Give age appropriate dose of NSAID. Avoid aspirin in children. Administer Paracetamol in dose of 15-20 mg/kg.  Local Anaesthetic (5% Xylocaine) can be applied at the site of injection an hour before  Administer sweet tasting liquid (2ml of 20% w/v sucrose or expressed breast milk) immediately before.  Child can even be breast fed immediately before Dr. Kamlesh Lala/Dr. Mrudula lala 9
  • 10. Shake Test for DTwP vaccine: Shake well the vaccine vial. After shaking, the vaccine sediment within 30 minutes leaving a deposit below a column of transparent fluid. This indicates that vaccine has been frozen in a cold chain. Discard such vial. Frozen vaccine increases the chances of local reaction and sterile abscess. Dr. Kamlesh Lala/Dr. Mrudula lala 10
  • 11. Benzyl Alcohol (BA) is used to increase the lipid solubility of esterified compounds and to prevent bacteria growth. It can cause destruction of cells and localised pain and inflammation.  After injection of the drug, BA is absorbed from the site causing active drug to precipitate fine crystals within the muscle. This causes pain after 4-12 hours of injection characterised by pain and inuration. Dr. Kamlesh Lala/Dr. Mrudula lala 11
  • 12. Tissue irritation is the most common cause of Post Injection Pain. It starts 12-24 hours after injection with warm, red, tender induration. This will fade after 72 hours.  Common with hormone injections.  More common in a brand manufactured by local drug company. (poor quality of raw material, excessive preservative, too much BA used) Dr. Kamlesh Lala/Dr. Mrudula lala 12
  • 13. Addition of Benzyl Benzoate (BB) can reduce it.  Gently warm the oily injection by rubbing it in between two palms so as to improve the viscosity of the drug.  Larger than 5 ml volume is not advised for intramuscular injection. It should be divided into multiple injection at different sites. Dr. Kamlesh Lala/Dr. Mrudula lala 13
  • 14. Use new syringe and needle every time.  Longer needle reduces redness and swelling, because medication is sure into the muscle. More so with Chloroquine and Diclofenac. So use 1.5” long needle for gluteal injection in adolescents and adults.  Use wide bore needle eg. 23g because narrow bore produces a jet under pressure causing muscle injury and pain.  For oily injection, use still wider bore needle (21g or 22g). Dr. Kamlesh Lala/Dr. Mrudula lala 14
  • 15. Use anterolateral thigh in children up to 2 years or even up to 5 years.  After that use deltoid muscle  In adults use gluteal muscle for oily injection or if volume is greater than 2 ml.  Larger volumes are better tolerated in larger muscle groups Dr. Kamlesh Lala/Dr. Mrudula lala 15
  • 16. Do not use the same site over and over again for days for multiple injections.  It may cause irritation and muscle injury; and increases the chances of infection.  Rotate the site. Dr. Kamlesh Lala/Dr. Mrudula lala 16
  • 17. After swabbing the site with spirit or alcohol, allow it to dry, or it may cause irritation.  Topical refrigerant (vapocoolant) spray immediately before the injection may reduce the short term pain.  Do not keep the air bubble inside the syringe.  Proper positioning of the patient allows to identify the site correctly.  Ensures patient’s comfort by muscle relaxation. Dr. Kamlesh Lala/Dr. Mrudula lala 17
  • 18. 1. Standard technique The needle is introduced at 900 with steady pressure and aspiration to be performed for 5- 10 seconds, drug is slowly injected over 5-10 secs., and the needle to be withdrawn slowly  2. Pragmatic technique The needle is introduced at 900 with steady pressure and no aspiration is to be performed, drug is rapidly injected over 1-2 secs., and the needle to be withdrawn rapidly Dr. Kamlesh Lala/Dr. Mrudula lala 18
  • 19. In a randomised controlled trial to compare acute pain response during immunisation in infants using these two techniques, it was found that Pragmatic technique is less painful than a standard one. Dr. Kamlesh Lala/Dr. Mrudula lala 19
  • 20. Z track technique. Skin is pulled downwards and laterally before injection. This displaces the skin and SC tissue leaving the muscle there only and uses the valve action to prevent leakage of medication into the SC tissue and later on irritation. Dr. Kamlesh Lala/Dr. Mrudula lala 20
  • 21. Dr. Kamlesh Lala/Dr. Mrudula lala 21
  • 22. Age appropriate non pharmacological techniques may provide distraction from pain.  Some of the distraction techniques are age appropriate toys, playing music, pretending to blow away pain, watching TV, conversation with child, deep breathing etc. Dr. Kamlesh Lala/Dr. Mrudula lala 22
  • 23. Dr. Kamlesh Lala/Dr. Mrudula lala 23
  • 24. Tactile Stimulation Rubbing or stroking the skin near the injection site with moderate intensity may decrease the pain in older children and adults. Dr. Kamlesh Lala/Dr. Mrudula lala 24
  • 25. Aspiration can be performed in non immunisation injections, but should be fast.  Ensure that the injection is deep into the muscle and fully through any subcutaneous fat. Injection into the fat may result in fat necrosis and abscess.  In case of larger volume injection, inject the drug slowly so as to reduce muscle fascia displacement (which may result in pain and scarring of muscle)  Withdraw the needle at the same angle as for penetration. Dr. Kamlesh Lala/Dr. Mrudula lala 25
  • 26. Dr. Kamlesh Lala/Dr. Mrudula lala 26
  • 27. Order of Injection For multiple injections, especially during immunisation, inject the most painful injection (DTP) last Dr. Kamlesh Lala/Dr. Mrudula lala 27
  • 28. Apply a little pressure to the injection site for 5- 10 seconds.  Do not massage or rub the site.  Do not apply hot or cold compresses. Clean cold wet wash cloth can be applied over sore area. Dr. Kamlesh Lala/Dr. Mrudula lala 28
  • 29. Patient should leave the clinic laughing……and not crying…. Dr. Kamlesh Lala/Dr. Mrudula lala 29