![OA – current status ,[object Object],[object Object],[object Object]](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
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Diacerein
- 1. Osteoarthritis The need for innovative therapeutic options?
- 3. OA – multiple spheres of influence
- 4. OA – multiple influences Injury Obesity Biomechanics Genetics Age / Sex Metabolic abnormalities Subchondral bone changes
- 6. DMOADs DMOADs What they need to do How they need to do Delay structural progression Prevent the OA Effect on Radiographic Joint Space Narrowing (JSN) Effect on progression to control JSN and pain / function relation Halting progression (improving the x-ray) Reversing progression (normalizing the x-ray)
- 8. Role of IL-1
- 9. Role of different therapies
- 10. Role of different therapies Diacerein Steroids NSAIDs
- 19. Case study 1 – before & after therapy with diacerein Before treatment After treatment
- 20. Case study 2 – before & after therapy with diacerein Before treatment After treatment
- 21. Case study 3 – before & after therapy with diacerein Before treatment After treatment
- 22. Study1 Arch Intern Med. 2006;166:1899-1906
- 23. Study2 Arch Intern Med. 2006;166:1899-1906
- 24. Study3 Arch Intern Med. 2006;166:1899-1906
- 25. Study4 Arch Intern Med. 2006;166:1899-1906
- 26. Study5 Arch Intern Med. 2006;166:1899-1906
- 27. Study6 Arch Intern Med. 2006;166:1899-1906
- 30. Summary of the studies