3. Microscale Fluidics
Used for heat transport around a circuit
On-Chip IC cooling, micro heat pipes
Used to transmit forces
Micropumps, diaphragms,
Used to create forces
Micro thrusters, micro-propulsion
Used to transport materials
Distribute cells, molecules to sensors
Used to react materials
Fuel cells, electrochemistry, reaction dynamics
3
4. Two approaches to Modeling Fluids
Continuum models
Works when point quantities can be large enough to contain
many molecules but still small compared to the scale of the flow
Molecular models
Must be used when these conditions are not met
4
6. BioMEMS/µFluidics module
Highlights
3D Navier-Stokes solver
Steady state & Transient
Newtonian & non-newtonian
Moving wall boundaries (Body fitted
co-ordinate mesh for complex geometries)
Adsorption & RedOx reactions
Galvanostatic/potentiostatic apps
Electrokinetics (Electro-osmosis,
electrophoresis & dielectrophoresis)
Acids, bases and ampholytes
7. BioMEMS/µFluidics applications
Micro Total Analysis Systems Array systems
µCapillary Zone Electrophoresis DNA Hybridization
µCapillary Isoelectric focusing Proteomics
µCapillary Isotachophoresis Protein patterning
µ mixers & µ separators
MEMS
T-sensors
Micropumps
Reaction chambers
Microvalves
Drug delivery systems
Flow cyclometry Fluid-membrane interaction
28. Electrokinetics Classification
Type of movement Electrokinetic
Coupling
Electrophoresis Charged surface Use an applied
moves relative to a electric field to induce
stationary liquid movement
Electro osmosis Liquid moves relative Use an applied
to a stationary electric field to induce
charged surface movement
54. Concentration skewing Minimized concentration skewing
Two reactants meeting at the junction
and reacting to form a new analyte.
Support for multivalent reactions is new
in v 8.5
Enhanced ion drag calculations allows
you to optimize elbow turns to minimize
concentration skews
Enhanced Chemical Reaction Enhanced transport behavior
1 Microfluidics with enhanced transport kinetics 2 Multivalent Ion drag calculations in electrokinetic
transport
55. Droplet moving around a pre-set track (top view) Droplet fission (top view)
Electrowetting on dielectric (EWOD)
3
3D Electrowetting calculations
56. Membrane
Inlet
Micro-mixing in a valve Flow mixing Fluid Structure Interaction Flow separation device
Concentration gradient evolution Y combiner Inlet flow - membrane interaction
Microfluidics• Electrokinetics • Transport stochiometry • Heat transfer • Free Surface Flow
• Fluid Structure Interaction • Electrochemistry • Micro-mixing • Electrophoresis
• Dielectrophoresis • Capillary flow and electro-separation • Electro-osmosis • Electro-
hydrodynamics • Flow cyclometry • Micro-pumps and valves
Electrokinetics Electro-osmotic driven flow Electrophoresis/Dielectrophoresis Free surface flow
Multiplex focusing Electrohydrodynamics for cooling High Frequency Waste separation Slide coater
57. Thank you
• • ध"यवाद • !"'&%ا ل
Grazie •Merci • Gracias • Danke •Obrigado • Dank U •Terima Kasih
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