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 Todesursache Nummer 1 in der westlichen Welt
 200.000 Herzinfarkttote in Deutschland/Jahr
´





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•
•
•
•
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•
Two
risk
variants
Two
normal
variants
Two
risk
variants
3 – 6M + 3 – 6 M + 6-8 M + 3-4 M + 12 M + 6-8 M + 10-14 M + 6-12 M
Gene
Symbol
KO Vector KO ESC Chimera Founder Backcross
to B6
Intercross GMC Backcross to
Apoe /Ldlr
Phenotyping
Atherosc /
Neointima
Cxcl12 --- --- --- --- --- lethal
Gucy1A3 --- --- --- --- --- Done in progress in progress
Mras --- --- --- --- Done Done in progress Done in progress
Adamts7 --- Done Done --- Done in progress in progress in progress
Cyp17a1 --- Done Done --- Done in progress in progress
Ppap2b --- Done Done --- lethal
Zc3hc1 --- Done Done --- Done in progress in progress in progress
Phactr1 Done Done in progress


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Das Institut für Integrative und Experimentelle Genomik stellt sich vor.
Das Institut für Integrative und Experimentelle Genomik stellt sich vor.

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Das Institut für Integrative und Experimentelle Genomik stellt sich vor.

  • 1.
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  • 3.
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  • 5.
  • 6.
  • 7.  Todesursache Nummer 1 in der westlichen Welt  200.000 Herzinfarkttote in Deutschland/Jahr
  • 8.
  • 9.
  • 10.
  • 11. ´
  • 12.
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  • 27.
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  • 29. 3 – 6M + 3 – 6 M + 6-8 M + 3-4 M + 12 M + 6-8 M + 10-14 M + 6-12 M Gene Symbol KO Vector KO ESC Chimera Founder Backcross to B6 Intercross GMC Backcross to Apoe /Ldlr Phenotyping Atherosc / Neointima Cxcl12 --- --- --- --- --- lethal Gucy1A3 --- --- --- --- --- Done in progress in progress Mras --- --- --- --- Done Done in progress Done in progress Adamts7 --- Done Done --- Done in progress in progress in progress Cyp17a1 --- Done Done --- Done in progress in progress Ppap2b --- Done Done --- lethal Zc3hc1 --- Done Done --- Done in progress in progress in progress Phactr1 Done Done in progress
  • 30.
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