The document summarizes the hypothalamic control of the pituitary gland and the hormones produced by its anterior and posterior lobes. The posterior lobe produces ADH and oxytocin, which regulate water balance and labor, respectively. The anterior lobe produces GH, PRL, ACTH, MSH, TSH, LH, FSH, and beta-LPH, which regulate growth, lactation, skin pigmentation, and reproduction. The hypothalamus controls pituitary function through releasing and inhibiting hormones.
2. Learning issues Hypothalamic control of pituitary gland Hormones of the posterior lobe : Hormones of the anterior lobe : ADH and Oxytocin GH , PRL, ACTH, MSH , TSH, LH, FSH and Beta-LPH (Lipotropin)
16. Physiological effects of prolactin (PRL): 1. Causes milk secretion 2. Increase production of casein & lactalbumin 3. Preventing ovulation in lactating women
17. Endocrinopathies Chromophobe adnomas of the anterior pituitary or prolactinoma -> hyperprolactinemia -> “ Galactorrhea” In women: blocking the action of gonadotropins on the ovaries -> hypogonadism -> infertility & amenorrhea and osteoporosis In men: 1. Hypogonadism 2. Decreased libido and impotence Treatment: surgical removal of tumor administration of bromocriptine (by stimulating DA receptor)