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Evolution of Computer assisted diagnosis and automation in Medical Practice Dr Genevieve Warner Learmonth, Honorary Senior Lecturer, Clinical Laboratory Sciences,  University of Cape Town
History and development ,[object Object],[object Object],[object Object]
Neural Networks in image recognition ,[object Object],[object Object],[object Object],[object Object],[object Object]
PapNet ,[object Object],[object Object],Tuberculosis epidemic
Support ,[object Object],[object Object]
TB or not TB ? ,[object Object],Then I met Kostas Veropoulos, a mathematical computer scientist who was “ looking for a project”
Mobile TB Diagnosis in South Africa Van / Lab visits peri urban areas.  Funded by Pick ‘n Pay
 
The search for bacilli on conventional sputum smears ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Project  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Morphology of and types of TB bacilli Mycobacterium Tuberculosis (2–4μm x 0.3–0.5μm) Mycobacterium bovis (1.5–1.9μm) Mycobacterium avium (1.0–1.8μm x 0.5μm) Mycobact. kansasii ( usually  4–5μm x 0.3μm)
Test Example: ZN stained slide (sputum smear at 40x magnification after image processing)
Image processing
Test Example: Auramine stained slide (sputum smear at 6 3 0 x magnification after image processing)   EDGE DETECTION
Results ---  specificity for a single bacillus Auramine stain ZN stain
Conclusions ,[object Object],[object Object],[object Object]
Cost Effectiveness ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Funding ,[object Object],[object Object],[object Object],[object Object],[object Object],Spotlight on africa
 
Presentations at Congress ,[object Object],[object Object],Automated Identification of Tubercle Bacilli in Sputum.  Veropoulos K, Learmonth G,  Campbell C,  Knight B,  Simpson J,  Journal of Analytical & Quantitative Cytology and Histology  1999 Vol.21, 4, 277 – 281
Publications and World wide presentations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Lack of Interest and Funding in TB epidemics  --- 1997/1998 ,[object Object],[object Object],[object Object],[object Object]
Futuristic Visions for Computerised Diagnosis
Finding the bacillus ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Computing and Image processing ,[object Object],[object Object],[object Object],[object Object]
Image Capture   and  Global Transmission ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
What happened ? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Future has arrived   Welcome to the Interscope

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Computer Assisted Diagnosis And Automation In Medical Practice

  • 1. Evolution of Computer assisted diagnosis and automation in Medical Practice Dr Genevieve Warner Learmonth, Honorary Senior Lecturer, Clinical Laboratory Sciences, University of Cape Town
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7. Mobile TB Diagnosis in South Africa Van / Lab visits peri urban areas. Funded by Pick ‘n Pay
  • 8.  
  • 9.
  • 10.
  • 11.  
  • 12. Morphology of and types of TB bacilli Mycobacterium Tuberculosis (2–4μm x 0.3–0.5μm) Mycobacterium bovis (1.5–1.9μm) Mycobacterium avium (1.0–1.8μm x 0.5μm) Mycobact. kansasii ( usually 4–5μm x 0.3μm)
  • 13. Test Example: ZN stained slide (sputum smear at 40x magnification after image processing)
  • 15. Test Example: Auramine stained slide (sputum smear at 6 3 0 x magnification after image processing) EDGE DETECTION
  • 16. Results --- specificity for a single bacillus Auramine stain ZN stain
  • 17.
  • 18.
  • 19.
  • 20.  
  • 21.
  • 22.
  • 23.
  • 24. Futuristic Visions for Computerised Diagnosis
  • 25.
  • 26.  
  • 27.
  • 28.
  • 29.
  • 30. The Future has arrived Welcome to the Interscope