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Statistics
Reference interval ,[object Object],[object Object],[object Object],[object Object]
Summarizing data “Average” ,[object Object],[object Object],[object Object]
Sensitivity ,[object Object],[object Object],[object Object],[object Object],[object Object]
Specificity ,[object Object],[object Object],[object Object],[object Object],[object Object]
Prevalence ,[object Object],[object Object],[object Object],[object Object]
PPV and NPV ,[object Object],[object Object]
Sensitivity  = TP/(TP+FN) Specificity = TN/(TN+FP) PPV = TP/(TP+FP) NPV = TN /(FN+TN) Disease No Disease Test Positive TP FP Test Negative FN TN
Example ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],Disease No Disease Test positive 90 1980 2070 Test Negative 10 7920 7930 100 9900 10,000
Answer ,[object Object],[object Object]
Likelihood ratio ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Example ,[object Object],[object Object],[object Object]
Answer ,[object Object],[object Object],[object Object],[object Object],[object Object]
SD and SE ,[object Object],[object Object]
Standard Error ,[object Object],[object Object]
[object Object],Sample size
If study number increases… ,[object Object],[object Object],[object Object],[object Object]
P- Value ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
Errors ,[object Object],[object Object],[object Object]
Power ,[object Object],[object Object],[object Object]
Relative Risk and Absolute Risk ,[object Object],[object Object],[object Object],[object Object],[object Object]
Odds ratio ,[object Object],[object Object],[object Object],[object Object],[object Object]
Example RR= I T /I C =  0.75= 25 % reduction in death. AR= I T -I C =  2 per 1000 (2/1000) Need to treat 1000 people to prevent 2 more deaths than control treatment. Number Deaths Cumulative incidence Treatment 1000 6 I T  = 6/1000 Control 1000 8 I C = 8/1000
Example Odds ratio= ad/bc RR= a(b+d)/b(a+c) Disease No Disease Positive test a c a + c Negative test b d b + d a+b c + d N
NNT ,[object Object],[object Object],[object Object],[object Object]
Selection bias ,[object Object]
Confounding ,[object Object]

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Statistics

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  • 4.
  • 5.
  • 6.
  • 7.
  • 8. Sensitivity = TP/(TP+FN) Specificity = TN/(TN+FP) PPV = TP/(TP+FP) NPV = TN /(FN+TN) Disease No Disease Test Positive TP FP Test Negative FN TN
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  • 10.
  • 11.
  • 12.
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  • 17.
  • 18.
  • 19.
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  • 21.
  • 22.
  • 23.
  • 24.
  • 25.
  • 26. Example RR= I T /I C = 0.75= 25 % reduction in death. AR= I T -I C = 2 per 1000 (2/1000) Need to treat 1000 people to prevent 2 more deaths than control treatment. Number Deaths Cumulative incidence Treatment 1000 6 I T = 6/1000 Control 1000 8 I C = 8/1000
  • 27. Example Odds ratio= ad/bc RR= a(b+d)/b(a+c) Disease No Disease Positive test a c a + c Negative test b d b + d a+b c + d N
  • 28.
  • 29.
  • 30.