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FoodMicroSystems
A Roadmap Towards Applications
in the Food Industry
Workshop – Madrid (Spain), 29 November 2013
Christophe Cotillon
Deputy Manager ACTIA
16, rue Claude Bernard, 75005 Paris, France
Phone: +33 1 44088615, E-mail: c.cotillon@actia-asso.eu
www.actia-asso.eu

FoodMicroSystems has been supported by the European Union’s Seventh Framework
Programme ([FP7/2007-2013] under grant agreement n°287634
Project ID
FoodMicroSystems
 European Commission funded Support Action
(798 K€ EC contribution)
 2 years from September 2011

 Coordination: ACTIA (France)
 9 partners
 Objective: initiate the implementation of

microsystems in food and drink sector
 Main results: 4 roadmaps

3
The consortium

4
Overview
Challenge
Unite two remote areas
 Food
 Micro systems

How?

13 meetings

Website

Promote cooperation between the two communities

3 technological
roadmaps
+ 1 application
roadmap

5 Reports
Needs of food industry
Potential of microsystems
+ consumer perception +
ethics + regulation
5
Approach

6
Microsystems (MST): From a
chip… to an instrument
Component or
subsystem

wafer
on-line

device
portable

benchtop

Miniaturised and cost-effective instruments
Food industry needs and demands
• Food safety (fast, portable, cheap and easy-touse devices)
• Food quality (continuous and simultaneous
measurements of several parameters)
• Food sustainability (water and energy
consumption, cleaning operations…)
• Authentification, traceability, detection of
frauds, adulteration…)
• Intelligent packaging
8
Where can MST be used?
Foodchain monitoring and traceability: safety and quality assessment stages

Farmers

Recollection

Industrials

Transport

Processing
(transforming, poisoning)

Retailers Consumers

Transport

Storage

Consumption

(degrading)
to eat, or not to eat.

Storage
(active-evolving, degrading)

Safety and Quality Assessment with MST
MST contribution: closeness to the foodstuff & power of analysis & speed
(multi-sensing, multipoint sensing, continuous monitoring, automation/non-specialist intervention)
10
Synthesis table of technological needs for Microsystems development in the different activity of the dairy sector:

Dairy sector
activities

Milk
collection,
transport,
storage

Treatment of
milk
Process
optimization
Ability indicator
of milk to the
growth of lactic
acid bacteria

Transformation
Process optimization
Ability indicator of milk to the clotting
Control online of pH kinetic (acidification during cheesemaking, deacidification
during ripening)
Control online of the drainage in curd and cheeses
Control online of clotting properties (firmness, rate of firming)
Control of the maturity of cheeses during the ripening
Control of the opening characteristics (hard cheeses)

Conditioning
Intelligent
packaging
Leak indicator
(ripening under film,
vacuum packaging)
Cold logistics:
Time/Temperature
indicator

Analyzing

Thematics
or
Technologies

Online indicative measurement of microbiological quality of products (Pathogens, Total Flora, Bacteriophage)
Measure/evaluation of the
lipolysis in milk
Control of
Measure of
Measure/evaluation of the fermentation activities (lactates, volatile fatty acids)
residual
whey proteins
Measure/evaluation of the mineralization (soluble and colloidal calcium)
antibiotics
denatured
Measure of the rate of salt and its distribution
on the farm
Measure/evaluation of the proteolysis in cheese

Cleaning
Online indicative measurement of cleaning and/or disinfection efficiency
Online indicative measurement of the presence of biofilms

Traceability
Miniaturized systems for products tracking along the production lines (Ex : RFID chips)
Miniaturized systems for
tracking the thermal history of
milk
11
Microsystem Techn.
Biosensors

Application
Volatile detection/quantification
to monitor quality deterioration,
e.g. in the headspace of the
packaged product
Food safety, usually off-line or

Micro-organism
near-line determination of
detection/quantification pathogens and/or spoilage
organisms

Meat

Food safety assurance and
shelf life determination in
combination with spoilage
models

Food safety assurance and
shelf life determination in
combination with spoilage
models

Spoilage detection

Food safety assurance and
shelf life determination in
combination with spoilage
models

Detection of antibiotics,
dioxins, etc.

Detection of antibiotics
(aquaculture) and
environmental residues

Detection of residues and
environmental substances

Micro-channel emulsification;
inkjet emulsification/particlre
production; production of fine
chemicals

Tracking and tracing

Communication of product specific
information to logistic systems in
the chain and/or retail (cassier) or
consumer systems (refrigerator,
microwave)
Volatile detection/quantification

Aroma/Gas sensors and to monitor quality deterioration,
e.g. in the headspace of the
sensing systems
packaged product

pH sensors and sensing
systems

Beverages

Detection of residues and
bacterio- and mycotoxins

Filtration, fractionation,
emulsification using MST devices
that combine uniformity with high
accuracy

Microfluidics

Fruit & Vegetables

Monitoring of storage
Real time determination of
Process control in dairy
conditions and real time
use-by-date of packaged
industry and real time
determination of use-by-date
products
determination of use-by-date
of packaged products

sampling

Processing technology

Dairy

Real time determination of
use-by-date of packaged
products

Food safety and regulatory

Chemical contaminant compliance, usually off-line lab-ondetection/quantification a-chip in combination with

Fish

Process monitoring

Food safety, spoilage
detection and process
monitoring (fermentation)

Pasteurisation by filtration;
fractionation of milk into
constituents; high quality
and/or multiple emulsions

emulsification; ingredient
production
Chain management; primary
production management;
origine determination;
authentication;
communication of sensor
data

Chain management;
time/temperature
monitoring

Removal of yeast or bacteria

Ingredient production

Indirect pathogen detection
Fish freshness monitoring by
via volatile by-products;
volatiles; differentiation
meat quality discrimination
between fresh fish and
according to escatol and
frozen/thawed fish
androsterona odours

pH and other ion detection as
potential contaminants in food; pH pH detection in pork meat
sensors as part of e-tongues for
for quality determination
quality assurance

Process control of dairy
product factories

Chain management

Authentication; in
combination with sensors:
primary production
management

i.e. Fruit Rippenes
monitoring by ethilene
vapours detection

Time/temperature
monitoring

identification of raw
materials, for quality and
antifraud in fruit juices, oils,..

Identification and quality
control of beverages;
antifraud,…

12
Functional trends
Functional trends

NEXUS Methodology
device x

func.
x

....
device 1

func.
2

func.
1
2000

2005

Functionality/performance

Functionality/customer benefit

Roadmapping methodology

2010

Product/Component trends
Product/Component trends

technology x device
x

....
technology 1

device
2

device
1
2000

2005

2010
Dairy technology technologies needed
Dairy industry: from drivers topriorities
Drivers

Industry
priorities

Capabilities
needed

Devices
needed

Time

Cost

Control of
purity

Quality

Efficient usage
of resources

Authenticity

Reduction
of waste

Proven
provenance

Detection of
Condition
Cold
Profiling &
unwanted
based
filtration ripeness
content
maintenance

Pathogen
Other
Fouling
Other
detection detection detection testing
Higher priority

Health

Better
emulsions

Better
emulsification
technologies

New
Protein
processing
detection?
technologies
Lower priority
Detection of the detection of chemical
Dairy Roadmap for chemical contamination,
contamination, residuesotherother
residues and and
Functionality / customer benefit

Lateral flow
sensor

Melamine

Metal
detector

Mobile chromatographic systems

Processing
contaminants:
chemicals or metal
parts / chips from the
equipment used

Pesticides /
Herbicides

Lateral flow
sensor

Microfluidic
lab-on-chip
sensor

Antibiotics
Quantitative
assays

Lateral flow
sensor

MultiAnalyte

Allergens
Microfluidic labon-chip sensor

Lactose

Time
3

5

10

years
Devices/functions needed for cheese quality control

Quality control for cheese
Aromatic
quality

Functionality / customer benefit

Gas sensors

Ripeness /
bacteria activity

Biosensors
Chemical sensors

Profiling (origin)

GC/MS
Sensors for ions and
organic molecules
Physical
Spectrometric

Taste
quality
Colour

Tactile
sensors

Physical
sensors
Dielectric
sensors

Imaging
Tenderness /
firmness

Texture
Holes /
openings

Mid infrared
spectroscopy
Imaging
Ultrasound
Integrate in
package label

Temperature / humidity

Moisture and salt content

3

Time
5

10

years
Level of Integration/Functionality

Technological Sensors gas sensors
Gas trends for
System Integration. Passive
Filters, Fabry-Perot.
Development of More
efficient absorption cells
Integrable low cost CMOS
compatible IR emitters
(< 1W)

New materials for more
performant IR detectors

New polymer substrates +
low temp. materials for
ultra low power systems

Integration with analog
electronics, FPGAs,…

Integration of low cost
microhotplates on standard
CMOS- SOI, < 10 mW
Nanomaterials as postprocessing at wafer level
New sensitive materials
NanoWires, CNTs…
for higher LOD: ppb

3

NDIR Optical
Systems
Ultra Low
Power
MOX Sensor
Arrays

MOX
Sensors
Arrays

MOX
Sensors

5

10

Time
(years)
Level of Integration/Functionality

E-nose
Technological trends for e-noses
Combination with
complementary systems
(GC…)

Complete
Sensing
systems

Integration of optimised
sensor arrays

Improvement of electronics control
systems

Simple
e-nose for
portability

Better types of gas sensors:
MOX, SAW, cantilever, optical,…

Development of new olfactory
models based on human
perception

3

Better Data
Processing
algorithms

5

10

Time
(years)
Level of Integration/Functionality

Technological trends for Sensors sensors
Bio-Chemical bio-chemical
Novel microfluidics,
sample processing, for
avoiding culturing.
FIA systems
Better surface immobilisation
techniques, membranes,
magnetic beads, for multiple use

New nano and biomaterials
for improving selectivity and
reducing interferences

Bio
Sensors

Multi sensing integration

FIA systems for making
calibration easy

Multiparame
tric systems

Chemical
Sensors

Non-silicon substrates
for low cost

Miniaturisation of chemical
transducers, for portability
New chemical membranes
for higher sensitivity and fast
response

3

5

10

Time
(years)
Microorganism detection using
the example of µPCR
Trend from lab to in-line measurement:
Example of pathogene detection

21
Industry constraints
•
•
•
•
•
•

Robustness of devices
Reliability of measurements
Compatibility with food processes
Time to process information and provide results
Cost per measurement
Sampling strategy (number of measures, when,
where, (pre)treatment of samples…)
• Cleanability
• Compatibility with current regulations for food
22
Consumer perception and ethical issues
•
•
•
•

Limited trust towards the food chain
Control of the technology
Use to track consumers after purchase (privacy violation)
Health concerns (chemical contamination, foreign
particles…)
• Incidence on the price of food product
• Effects on environment (bio-accumulation of particles,
packaging…)
• Transparancy about application and clear regulatory
frame
23
Overall conclusions from the Microsystems for
Food Roadmapping

=> the food sector is a significant market to MST
developers
– MST can help the food sector to address its key
challenges (safety, quality, authenticity and optimise
the use of resources)
– There are strong needs for new solutions (FMS has
many examples in its reports)

=> FMS provides ideas for H2020 (Innovation projects)
– Roadmaps on 3 sectors can be used as source of
inspiration by the EC in H2020
24
MNT for Food – The way forward…

• Opportunities for MNT:
–
–
–
–

Technologies to increase shelflife & improve taste / nutritional value
Even new food products are possible (e.g. through emulsification)
Bring Lab analytics to the manufacturing line
Re-use results from other sectors (medical) research

• How to move forward:
– Funding: national, EC - coordinate ICT and food funding?
– Networking / communication along the “MNT - Food industry”
– Continue FoodMicroSystems roadmapping process
25
Thank you for your attention!
Preliminary FoodMicroSystems roadmaps have been published
at: http://www.foodmicrosystems.eu/?page_id=1159
FoodMicroSystems: EC-funded Coordination Action to provide a Roadmap of the "Microsystems for Food" Sector
www.foodmicrosystems.eu

26

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20131129 FFF El proyecto Foodmanufuture_Christophe Cotillon

  • 1.
  • 2. FoodMicroSystems A Roadmap Towards Applications in the Food Industry Workshop – Madrid (Spain), 29 November 2013 Christophe Cotillon Deputy Manager ACTIA 16, rue Claude Bernard, 75005 Paris, France Phone: +33 1 44088615, E-mail: c.cotillon@actia-asso.eu www.actia-asso.eu FoodMicroSystems has been supported by the European Union’s Seventh Framework Programme ([FP7/2007-2013] under grant agreement n°287634
  • 3. Project ID FoodMicroSystems  European Commission funded Support Action (798 K€ EC contribution)  2 years from September 2011  Coordination: ACTIA (France)  9 partners  Objective: initiate the implementation of microsystems in food and drink sector  Main results: 4 roadmaps 3
  • 5. Overview Challenge Unite two remote areas  Food  Micro systems How? 13 meetings Website Promote cooperation between the two communities 3 technological roadmaps + 1 application roadmap 5 Reports Needs of food industry Potential of microsystems + consumer perception + ethics + regulation 5
  • 7. Microsystems (MST): From a chip… to an instrument Component or subsystem wafer on-line device portable benchtop Miniaturised and cost-effective instruments
  • 8. Food industry needs and demands • Food safety (fast, portable, cheap and easy-touse devices) • Food quality (continuous and simultaneous measurements of several parameters) • Food sustainability (water and energy consumption, cleaning operations…) • Authentification, traceability, detection of frauds, adulteration…) • Intelligent packaging 8
  • 9. Where can MST be used? Foodchain monitoring and traceability: safety and quality assessment stages Farmers Recollection Industrials Transport Processing (transforming, poisoning) Retailers Consumers Transport Storage Consumption (degrading) to eat, or not to eat. Storage (active-evolving, degrading) Safety and Quality Assessment with MST MST contribution: closeness to the foodstuff & power of analysis & speed (multi-sensing, multipoint sensing, continuous monitoring, automation/non-specialist intervention)
  • 10. 10
  • 11. Synthesis table of technological needs for Microsystems development in the different activity of the dairy sector: Dairy sector activities Milk collection, transport, storage Treatment of milk Process optimization Ability indicator of milk to the growth of lactic acid bacteria Transformation Process optimization Ability indicator of milk to the clotting Control online of pH kinetic (acidification during cheesemaking, deacidification during ripening) Control online of the drainage in curd and cheeses Control online of clotting properties (firmness, rate of firming) Control of the maturity of cheeses during the ripening Control of the opening characteristics (hard cheeses) Conditioning Intelligent packaging Leak indicator (ripening under film, vacuum packaging) Cold logistics: Time/Temperature indicator Analyzing Thematics or Technologies Online indicative measurement of microbiological quality of products (Pathogens, Total Flora, Bacteriophage) Measure/evaluation of the lipolysis in milk Control of Measure of Measure/evaluation of the fermentation activities (lactates, volatile fatty acids) residual whey proteins Measure/evaluation of the mineralization (soluble and colloidal calcium) antibiotics denatured Measure of the rate of salt and its distribution on the farm Measure/evaluation of the proteolysis in cheese Cleaning Online indicative measurement of cleaning and/or disinfection efficiency Online indicative measurement of the presence of biofilms Traceability Miniaturized systems for products tracking along the production lines (Ex : RFID chips) Miniaturized systems for tracking the thermal history of milk 11
  • 12. Microsystem Techn. Biosensors Application Volatile detection/quantification to monitor quality deterioration, e.g. in the headspace of the packaged product Food safety, usually off-line or Micro-organism near-line determination of detection/quantification pathogens and/or spoilage organisms Meat Food safety assurance and shelf life determination in combination with spoilage models Food safety assurance and shelf life determination in combination with spoilage models Spoilage detection Food safety assurance and shelf life determination in combination with spoilage models Detection of antibiotics, dioxins, etc. Detection of antibiotics (aquaculture) and environmental residues Detection of residues and environmental substances Micro-channel emulsification; inkjet emulsification/particlre production; production of fine chemicals Tracking and tracing Communication of product specific information to logistic systems in the chain and/or retail (cassier) or consumer systems (refrigerator, microwave) Volatile detection/quantification Aroma/Gas sensors and to monitor quality deterioration, e.g. in the headspace of the sensing systems packaged product pH sensors and sensing systems Beverages Detection of residues and bacterio- and mycotoxins Filtration, fractionation, emulsification using MST devices that combine uniformity with high accuracy Microfluidics Fruit & Vegetables Monitoring of storage Real time determination of Process control in dairy conditions and real time use-by-date of packaged industry and real time determination of use-by-date products determination of use-by-date of packaged products sampling Processing technology Dairy Real time determination of use-by-date of packaged products Food safety and regulatory Chemical contaminant compliance, usually off-line lab-ondetection/quantification a-chip in combination with Fish Process monitoring Food safety, spoilage detection and process monitoring (fermentation) Pasteurisation by filtration; fractionation of milk into constituents; high quality and/or multiple emulsions emulsification; ingredient production Chain management; primary production management; origine determination; authentication; communication of sensor data Chain management; time/temperature monitoring Removal of yeast or bacteria Ingredient production Indirect pathogen detection Fish freshness monitoring by via volatile by-products; volatiles; differentiation meat quality discrimination between fresh fish and according to escatol and frozen/thawed fish androsterona odours pH and other ion detection as potential contaminants in food; pH pH detection in pork meat sensors as part of e-tongues for for quality determination quality assurance Process control of dairy product factories Chain management Authentication; in combination with sensors: primary production management i.e. Fruit Rippenes monitoring by ethilene vapours detection Time/temperature monitoring identification of raw materials, for quality and antifraud in fruit juices, oils,.. Identification and quality control of beverages; antifraud,… 12
  • 13. Functional trends Functional trends NEXUS Methodology device x func. x .... device 1 func. 2 func. 1 2000 2005 Functionality/performance Functionality/customer benefit Roadmapping methodology 2010 Product/Component trends Product/Component trends technology x device x .... technology 1 device 2 device 1 2000 2005 2010
  • 14. Dairy technology technologies needed Dairy industry: from drivers topriorities Drivers Industry priorities Capabilities needed Devices needed Time Cost Control of purity Quality Efficient usage of resources Authenticity Reduction of waste Proven provenance Detection of Condition Cold Profiling & unwanted based filtration ripeness content maintenance Pathogen Other Fouling Other detection detection detection testing Higher priority Health Better emulsions Better emulsification technologies New Protein processing detection? technologies Lower priority
  • 15. Detection of the detection of chemical Dairy Roadmap for chemical contamination, contamination, residuesotherother residues and and Functionality / customer benefit Lateral flow sensor Melamine Metal detector Mobile chromatographic systems Processing contaminants: chemicals or metal parts / chips from the equipment used Pesticides / Herbicides Lateral flow sensor Microfluidic lab-on-chip sensor Antibiotics Quantitative assays Lateral flow sensor MultiAnalyte Allergens Microfluidic labon-chip sensor Lactose Time 3 5 10 years
  • 16. Devices/functions needed for cheese quality control Quality control for cheese Aromatic quality Functionality / customer benefit Gas sensors Ripeness / bacteria activity Biosensors Chemical sensors Profiling (origin) GC/MS Sensors for ions and organic molecules Physical Spectrometric Taste quality Colour Tactile sensors Physical sensors Dielectric sensors Imaging Tenderness / firmness Texture Holes / openings Mid infrared spectroscopy Imaging Ultrasound Integrate in package label Temperature / humidity Moisture and salt content 3 Time 5 10 years
  • 17. Level of Integration/Functionality Technological Sensors gas sensors Gas trends for System Integration. Passive Filters, Fabry-Perot. Development of More efficient absorption cells Integrable low cost CMOS compatible IR emitters (< 1W) New materials for more performant IR detectors New polymer substrates + low temp. materials for ultra low power systems Integration with analog electronics, FPGAs,… Integration of low cost microhotplates on standard CMOS- SOI, < 10 mW Nanomaterials as postprocessing at wafer level New sensitive materials NanoWires, CNTs… for higher LOD: ppb 3 NDIR Optical Systems Ultra Low Power MOX Sensor Arrays MOX Sensors Arrays MOX Sensors 5 10 Time (years)
  • 18. Level of Integration/Functionality E-nose Technological trends for e-noses Combination with complementary systems (GC…) Complete Sensing systems Integration of optimised sensor arrays Improvement of electronics control systems Simple e-nose for portability Better types of gas sensors: MOX, SAW, cantilever, optical,… Development of new olfactory models based on human perception 3 Better Data Processing algorithms 5 10 Time (years)
  • 19. Level of Integration/Functionality Technological trends for Sensors sensors Bio-Chemical bio-chemical Novel microfluidics, sample processing, for avoiding culturing. FIA systems Better surface immobilisation techniques, membranes, magnetic beads, for multiple use New nano and biomaterials for improving selectivity and reducing interferences Bio Sensors Multi sensing integration FIA systems for making calibration easy Multiparame tric systems Chemical Sensors Non-silicon substrates for low cost Miniaturisation of chemical transducers, for portability New chemical membranes for higher sensitivity and fast response 3 5 10 Time (years)
  • 21. Trend from lab to in-line measurement: Example of pathogene detection 21
  • 22. Industry constraints • • • • • • Robustness of devices Reliability of measurements Compatibility with food processes Time to process information and provide results Cost per measurement Sampling strategy (number of measures, when, where, (pre)treatment of samples…) • Cleanability • Compatibility with current regulations for food 22
  • 23. Consumer perception and ethical issues • • • • Limited trust towards the food chain Control of the technology Use to track consumers after purchase (privacy violation) Health concerns (chemical contamination, foreign particles…) • Incidence on the price of food product • Effects on environment (bio-accumulation of particles, packaging…) • Transparancy about application and clear regulatory frame 23
  • 24. Overall conclusions from the Microsystems for Food Roadmapping => the food sector is a significant market to MST developers – MST can help the food sector to address its key challenges (safety, quality, authenticity and optimise the use of resources) – There are strong needs for new solutions (FMS has many examples in its reports) => FMS provides ideas for H2020 (Innovation projects) – Roadmaps on 3 sectors can be used as source of inspiration by the EC in H2020 24
  • 25. MNT for Food – The way forward… • Opportunities for MNT: – – – – Technologies to increase shelflife & improve taste / nutritional value Even new food products are possible (e.g. through emulsification) Bring Lab analytics to the manufacturing line Re-use results from other sectors (medical) research • How to move forward: – Funding: national, EC - coordinate ICT and food funding? – Networking / communication along the “MNT - Food industry” – Continue FoodMicroSystems roadmapping process 25
  • 26. Thank you for your attention! Preliminary FoodMicroSystems roadmaps have been published at: http://www.foodmicrosystems.eu/?page_id=1159 FoodMicroSystems: EC-funded Coordination Action to provide a Roadmap of the "Microsystems for Food" Sector www.foodmicrosystems.eu 26