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Common Pediatric Skin and
Soft Tissue Conditions
Dr.Md.Shahidul Islam
Assistant Professor,Dermatology
CBMCB
Erythema Toxicum
Neonatorum
Impressive title - harmless skin condition
Erythematous macule with a central tiny papule, seen
anywhere - except the palms and soles.
The lesions are packed with eosinophils, and there
may be accompanying eosinophilia in the blood
count.
The cause is unknown, and no treatment is required as
the rash disappears after 1-2 weeks.
Miliaria
Prickly heat, sweat rash
Many red macules with central papules,
vesicles or pustules are present.
These may be on the trunk, diaper area, head
or neck.
Subcutaneous Fat Necrosis
Self limited, benign condition
Sharply demarcated reddish to violaceous
plaques or nodules
Etiology uncertain
Onset first few days- weeks of life
Cheeks, back, buttocks, arms, and thighs
Infantile Atopic Dermatitis
Cause is unknown
Red, itchy papules and plaques that ooze
and crust
Sites of Predilection
Face in the young
Extensor surfaces of the arms and legs 8-10 mo.
Antecubital and popliteal fossa , neck, face in
older
Differential DiagnosisAtopic Dermatitis
Seborrheic dermatitis
Contact dermatitis
Nummular eczema
Psoriasis
Scabies
Eczema- Treatment
Avoidance or elimination of predisposing
factors
Hydration and lubrication of dry skin
Anti-pruritic agents
Topical steroids
Seborrheic Dermatitis
Common, generally self-limiting
Its cause remains ill-understood
There is a genetic predisposition
Most frequent between the ages of 1 to 6 mo.
Greasy, salmon-colored scaling eruption
Hair-bearing and intertriginous areas
The rash causes no discomfort or itching
Seborrheic DermatitisTreatment
Anti-seborrheic shampoo
Topical steroids
Pityriasis Rosea
Mild inflammatory exanthem of unknown
cause, maybe viral
Benign, self limited disorder
Occasionally there are prodromal symptoms
including malaise, headache, sore throat,
fatigue, and arthralgia.
Herald patch- pink in color and scalymimicking tinea corporis
Diaper Rash
Candidal Dermatitis
Starts off in the deep flexures which show
widespread erythema on the buttocks-beefy red
color
There are also raised edge, sharp marginization
and white scale at the border of lesions, with
pinpoint pustulo-vesicular satellite lesions
Seborrheic Dermatitis
Salmon-colored greasy lesions with
yellowish scale and predilection for
intertriginous areas
Involvement of the scalp, face, neck, and
post auricular and flexural areas
Irritant Dermatitis
Rash confined to the convex surfaces of the
buttocks,perineal area, lower abdomen, and
proximal thighs, sparing the intertriginous
creases
Excessive heat, moisture, and sweat
retention
Harsh soaps, detergents, and topical
medications
Viral Exanthems
Smallpox- Variola
Fatality 40 %
First invades upper respiratory tract
From lymph nodes it spreads via
hematogenous spread
Chills, fever, headache, delirium, SZ
Face to upper arms and trunk, and finally to
lower legs
Chickenpox-Varicella
Herpes virus varicellae
Incubation period 10-21 days
Fever, malaise, cough, irritability, pruritus
Papules→vesicles →crusting
Spreads centripetally
Varicella
Complications:
Bacterial superinfection
CNS involvement
Pneumonia
Hepatitis, arthritis
Reye’s syndrome

VZIG
Varicella – Treatment
Oral acyclovir- indications
Healthy nonpregnant teenagers and adults
Children > 1 yr with chronic cutaneous or
pulmonary conditions
Patients on chronic salicylate therapy
Patients receiving short or intermittent courses of
aerosolized corticosteroids

Dose: 80 mg/kg/day in four divided doses for
5 days
Varicella – Post exposure
VZIG (1 vial/5 kg IM) :
Pts on high dose steroids
Immunocompromised without a history of CP
Pregnant women
Newborns exposed 5 days prior to birth and 2 days
after delivery
Neonates born to nonimmune mothers
Hospitalized premature infants < 28 weeks’
gestation
Measles
Rubeola- paramyxovirus
Occurs in epidemics
Incubation 8-12 days
Fever, lethargy, Cough, coryza, conjunctivitis
with clear discharge and photophobia
Koplik spots
Rash begins on the face and spreads to trunk and
extremities
Measles – Post Exposure
Immunoglobulin therapy- indications
All susceptible contacts
Infants 5 mo. To 1 year of age
Immunocompromised
Pregnant women
<5 mo. If mother without immunity

Live measles virus vaccine- contraindication
Immunocompromised- excluding HIV
Pregnancy
Allergy to eggs, or neomycin
Rubella
German Measles
Epidemic nature
Winter-spring
Prodrome
Face → neck → trunk
Lymphadenopathy
Serologic testing
Hand-Foot-Mouth Disease
Enteroviruses
coxsackieviruses A and B
echoviruses

Vesicular lesions, may be petechial
Associated with aseptic meningitis,
myocarditis
Erythema Infectiosum
Fifth disease
Mildly contagious, parvovirus B-19
Pre-school and young school-age children
Prodrome: mild malaise
Rash: “slapped cheek”, circumoral pallor,
peripheral mild macular distribution
Complication
Exanthem Subitum
Roseola Infantum
Children 6-19 months
Abrupt onset of high fever
Febrile seizures
Rash develops after fever dissipates
Mainly on trunk
Infectious Mononucleosis
Acute, self limited illness
Epstein-Barr virus
Oral transmission – incubation 30-50 days
Fever, fatigue, pharyngitis, LA, splenomegaly,
atypical lymphocytosis
Exanthem is seen in 10-15%
Erythematous, maculopapular, morbilliform,
scarlatiniform, urticarial, hemorrhagic, or even
nodular
Bacterial Exanthems
Impetigo
Superficial infection of the dermis
Two types:
Impetigo contagiosa
Bullous impetigo

Etiology
Group A ß hemolytic streptococcus
Coagulase positive S. aureus

Treatment : Keflex, erythromycin, Bactroban
Scarlet Fever
Toxin producing strain of group A β-hemolytic
streptococcus
Strep pharyngitis with systemic complaints
Rash from neck to trunk to extremities
Sandpaper feel, erythema, warmth
White and red strawberry tongue
Petechiae in linear form
Complications
Treatment
Staphylococcal Scalded-Skin
Syndrome
Generally in less than 5 years of age
Induced by exotoxin produced by staphylococci
Fever, papular erythematous rash starting around
mouth- not involving oral mucosa
Positive Nikolsky’s sign
Diagnosis: Tzanck test, bacterial culture
Treatment
Complications
Meningococcemia
Usually sudden onset of fever, chills, myalgia,
and arthralgia
Rash is macular, nonpruritic, erythematous
lesions
Petechial rash develops in 75% of cases
Neisseria meningitides
Fever, rash, hypotension, shock, DIC
Treatment: PCN G
Differential Diagnosis
Gonococcemia
HSP
Typhoid fever
Rickettsial disease
Erythema multiforme
Purpura fulminans
Rocky Mountain Spotted
Fever
Most common rickettsial infection in US
Abrupt fever, headache, and myalgia
Rash from extremities towards trunk
Macules→petechiae
Treatment
Tetracycline
Doxycycline
Chloramphenicol
Cellulitis
Most common organisms:
S. aureus
S. pyogenes
H. influenza type B (HIB)

Most common sites?
CBC, x-ray?
Cellulitis- Treatment
IV antibiotics in:
Immunocompromised
Ill appearing
Suspected bacteremia
<6 mo. Of age
WBC> 15K
High fever
Rapidly progressing
Periorbital- Orbital Cellulitis
S. aureus, S. pneumoniae, and HIB
CBC, blood culture, CT
LP?
IV antibiotics
Admit
Fungal Infections
Henoch-Schnlein Purpura
No clear etiologic agent, often post viral
2-10 years of age
Palpable purpura over the buttocks and LE
Transient migratory arthritis
Renal and GI involvement
Kawasaki Syndrome
Unknown etiology
Peak incidence 18-24 months
Clinical findings:
Fever for at least five days
Conjunctivitis
Polymorphous rash
Oral cavity changes
Cervical adenopathy
 Paediatric rash

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Paediatric rash

  • 1. Common Pediatric Skin and Soft Tissue Conditions Dr.Md.Shahidul Islam Assistant Professor,Dermatology CBMCB
  • 2.
  • 3. Erythema Toxicum Neonatorum Impressive title - harmless skin condition Erythematous macule with a central tiny papule, seen anywhere - except the palms and soles. The lesions are packed with eosinophils, and there may be accompanying eosinophilia in the blood count. The cause is unknown, and no treatment is required as the rash disappears after 1-2 weeks.
  • 4.
  • 5. Miliaria Prickly heat, sweat rash Many red macules with central papules, vesicles or pustules are present. These may be on the trunk, diaper area, head or neck.
  • 6.
  • 7. Subcutaneous Fat Necrosis Self limited, benign condition Sharply demarcated reddish to violaceous plaques or nodules Etiology uncertain Onset first few days- weeks of life Cheeks, back, buttocks, arms, and thighs
  • 8.
  • 9. Infantile Atopic Dermatitis Cause is unknown Red, itchy papules and plaques that ooze and crust Sites of Predilection Face in the young Extensor surfaces of the arms and legs 8-10 mo. Antecubital and popliteal fossa , neck, face in older
  • 10.
  • 11. Differential DiagnosisAtopic Dermatitis Seborrheic dermatitis Contact dermatitis Nummular eczema Psoriasis Scabies
  • 12. Eczema- Treatment Avoidance or elimination of predisposing factors Hydration and lubrication of dry skin Anti-pruritic agents Topical steroids
  • 13.
  • 14.
  • 15.
  • 16. Seborrheic Dermatitis Common, generally self-limiting Its cause remains ill-understood There is a genetic predisposition Most frequent between the ages of 1 to 6 mo. Greasy, salmon-colored scaling eruption Hair-bearing and intertriginous areas The rash causes no discomfort or itching
  • 17.
  • 18.
  • 20.
  • 21. Pityriasis Rosea Mild inflammatory exanthem of unknown cause, maybe viral Benign, self limited disorder Occasionally there are prodromal symptoms including malaise, headache, sore throat, fatigue, and arthralgia. Herald patch- pink in color and scalymimicking tinea corporis
  • 23.
  • 24. Candidal Dermatitis Starts off in the deep flexures which show widespread erythema on the buttocks-beefy red color There are also raised edge, sharp marginization and white scale at the border of lesions, with pinpoint pustulo-vesicular satellite lesions
  • 25.
  • 26.
  • 27. Seborrheic Dermatitis Salmon-colored greasy lesions with yellowish scale and predilection for intertriginous areas Involvement of the scalp, face, neck, and post auricular and flexural areas
  • 28.
  • 29. Irritant Dermatitis Rash confined to the convex surfaces of the buttocks,perineal area, lower abdomen, and proximal thighs, sparing the intertriginous creases Excessive heat, moisture, and sweat retention Harsh soaps, detergents, and topical medications
  • 30.
  • 31.
  • 33.
  • 34. Smallpox- Variola Fatality 40 % First invades upper respiratory tract From lymph nodes it spreads via hematogenous spread Chills, fever, headache, delirium, SZ Face to upper arms and trunk, and finally to lower legs
  • 35.
  • 36. Chickenpox-Varicella Herpes virus varicellae Incubation period 10-21 days Fever, malaise, cough, irritability, pruritus Papules→vesicles →crusting Spreads centripetally
  • 38. Varicella – Treatment Oral acyclovir- indications Healthy nonpregnant teenagers and adults Children > 1 yr with chronic cutaneous or pulmonary conditions Patients on chronic salicylate therapy Patients receiving short or intermittent courses of aerosolized corticosteroids Dose: 80 mg/kg/day in four divided doses for 5 days
  • 39. Varicella – Post exposure VZIG (1 vial/5 kg IM) : Pts on high dose steroids Immunocompromised without a history of CP Pregnant women Newborns exposed 5 days prior to birth and 2 days after delivery Neonates born to nonimmune mothers Hospitalized premature infants < 28 weeks’ gestation
  • 40.
  • 41.
  • 42. Measles Rubeola- paramyxovirus Occurs in epidemics Incubation 8-12 days Fever, lethargy, Cough, coryza, conjunctivitis with clear discharge and photophobia Koplik spots Rash begins on the face and spreads to trunk and extremities
  • 43. Measles – Post Exposure Immunoglobulin therapy- indications All susceptible contacts Infants 5 mo. To 1 year of age Immunocompromised Pregnant women <5 mo. If mother without immunity Live measles virus vaccine- contraindication Immunocompromised- excluding HIV Pregnancy Allergy to eggs, or neomycin
  • 44. Rubella German Measles Epidemic nature Winter-spring Prodrome Face → neck → trunk Lymphadenopathy Serologic testing
  • 45.
  • 46. Hand-Foot-Mouth Disease Enteroviruses coxsackieviruses A and B echoviruses Vesicular lesions, may be petechial Associated with aseptic meningitis, myocarditis
  • 47.
  • 48. Erythema Infectiosum Fifth disease Mildly contagious, parvovirus B-19 Pre-school and young school-age children Prodrome: mild malaise Rash: “slapped cheek”, circumoral pallor, peripheral mild macular distribution Complication
  • 49.
  • 50. Exanthem Subitum Roseola Infantum Children 6-19 months Abrupt onset of high fever Febrile seizures Rash develops after fever dissipates Mainly on trunk
  • 51.
  • 52. Infectious Mononucleosis Acute, self limited illness Epstein-Barr virus Oral transmission – incubation 30-50 days Fever, fatigue, pharyngitis, LA, splenomegaly, atypical lymphocytosis Exanthem is seen in 10-15% Erythematous, maculopapular, morbilliform, scarlatiniform, urticarial, hemorrhagic, or even nodular
  • 54.
  • 55. Impetigo Superficial infection of the dermis Two types: Impetigo contagiosa Bullous impetigo Etiology Group A ß hemolytic streptococcus Coagulase positive S. aureus Treatment : Keflex, erythromycin, Bactroban
  • 56.
  • 57.
  • 58. Scarlet Fever Toxin producing strain of group A β-hemolytic streptococcus Strep pharyngitis with systemic complaints Rash from neck to trunk to extremities Sandpaper feel, erythema, warmth White and red strawberry tongue Petechiae in linear form Complications Treatment
  • 59.
  • 60. Staphylococcal Scalded-Skin Syndrome Generally in less than 5 years of age Induced by exotoxin produced by staphylococci Fever, papular erythematous rash starting around mouth- not involving oral mucosa Positive Nikolsky’s sign Diagnosis: Tzanck test, bacterial culture Treatment Complications
  • 61.
  • 62. Meningococcemia Usually sudden onset of fever, chills, myalgia, and arthralgia Rash is macular, nonpruritic, erythematous lesions Petechial rash develops in 75% of cases Neisseria meningitides Fever, rash, hypotension, shock, DIC Treatment: PCN G
  • 63. Differential Diagnosis Gonococcemia HSP Typhoid fever Rickettsial disease Erythema multiforme Purpura fulminans
  • 64.
  • 65. Rocky Mountain Spotted Fever Most common rickettsial infection in US Abrupt fever, headache, and myalgia Rash from extremities towards trunk Macules→petechiae Treatment Tetracycline Doxycycline Chloramphenicol
  • 66.
  • 67. Cellulitis Most common organisms: S. aureus S. pyogenes H. influenza type B (HIB) Most common sites? CBC, x-ray?
  • 68. Cellulitis- Treatment IV antibiotics in: Immunocompromised Ill appearing Suspected bacteremia <6 mo. Of age WBC> 15K High fever Rapidly progressing
  • 69.
  • 70. Periorbital- Orbital Cellulitis S. aureus, S. pneumoniae, and HIB CBC, blood culture, CT LP? IV antibiotics Admit
  • 71.
  • 73.
  • 74.
  • 75.
  • 76.
  • 77. Henoch-Schnlein Purpura No clear etiologic agent, often post viral 2-10 years of age Palpable purpura over the buttocks and LE Transient migratory arthritis Renal and GI involvement
  • 78.
  • 79. Kawasaki Syndrome Unknown etiology Peak incidence 18-24 months Clinical findings: Fever for at least five days Conjunctivitis Polymorphous rash Oral cavity changes Cervical adenopathy