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Fournier Gangrene.pptx
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11. Pathophysiology:Pathogens
Polymicrobial infection with an average of 4 isolates per
case
• Escherichia coli
• Bacteroides
• Proteus
• Staphylococcus
• Enterococcus
• Streptococcus (aerobic and anaerobic)
• Pseudomonas
• Klebsiella
• ClostridiumCandida albicans
12. Pathophysiology
• Infection spreads along the anatomical fascial
planes, often sparing the deep muscular structures
and, to variable degrees, the overlying skin.
14. Anatomy
• Camper fascia
• Scarpa fascia
• Colles fascia while it is continuous with
• Dartos fascia of the penis and scrotum
• Branches of the external and internal
pudendal arteries supply the scrotal wall.
• Branches of the external pudendal arteries
travels within Camper fascia
• Superiorly, Scarpa and Camper fascia
coalesce and attach to the clavicles,
18. Demography
• Relatively uncommon, but the exact
incidence of the disease is unknown.
• No seasonal variation occurs.
• All over the world.
• Typical case -elderly man in his sixth or
seventh decade of life with comorbid
diseases
• The male-to-female ratio is approximately
10:1.
• Homosexual men may be at higher risk,
34. Tissue Diagnosis
Histological features
• Necrosis of the superficial and deep fascial
planes
• Fibrinoid coagulation of the nutrient
arterioles
• Polymorphonuclear cell infiltration
• Microorganisms identified within the
involved tissues
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