SlideShare ist ein Scribd-Unternehmen logo
1 von 12
Downloaden Sie, um offline zu lesen
HET408 Medical Imaging

The Physics of
Doppler Ultrasound
1

The Doppler Principle

The basis of Doppler ultrasonography is the fact that reflected/scattered ultrasonic waves from a moving interface will undergo a frequency shift. In general the
magnitude and the direction of this shift will provide information regarding the
motion of this interface. To appreciate this very general fact we need to consider
the relationship between the frequency, fS , of waves produced by a moving source
and the frequency, fR , of the waves received by a moving receiver. For simplicity
we shall assume that the source and receiver are moving along the same line.
The argument that follows will generalise to three dimensions if wave speed is
isotropic and the source produces spherical waves.
At t = 0, let the source, S, and receiver, R, be separated by a distance d
d

S

R

v

v

S

R

At t = 0 let S emit a wave that reaches R at a time t later
ct

d

v t
R

S

R

R’

In this time t the receiver will have moved a distance vR t and the wave, propagating with velocity c will have traveled a distance c t. Thus

ct = d + vR t
d
t =
c − vR

or

Now at time τ , the source will have moved a distance τ vS . Let the wave emitted
at that instant be received at time t by R.
In this time R would have traveled a total distance of vR t , and thus
c(t’-

τ)

d

v

S

v t’
R

τ

S

S’

R

R’’

c(t − τ ) = (d − vs τ ) + vR t
d + (c − vs )τ
t =
c − vR

or

Thus for the receiver the interval between the waves has been
τ =t −t=

c − vS
τ
c − vR

whereas for the source the interval between the waves has been τ . Now the
number of waves emitted in τ by the source must be equal to the number of
waves received by the receiver in τ i.e
fR τ = f S τ
Thus

fR =
For vS , vR

c

1

c − vR
fS
c − vS

(1)

we can develop the following approximation,

1 − vR /c
fS
1 − vS /c
vR
vS
= 1−
1−
c
c

fR =

1

this is reasonable as c
v ≤ 2m s−1

−1

1500m s−1 and in Doppler measurements, e.g in blood flow,
The last term on the right-hand side can be expanded using the binomial expansion
(1 + x)n = 1 + nx +
thus for x

n(n − 1) 2
x + ···
2!

1, higher order terms become unimportant and thus

fR

vR
vS
1+
c
c
vRS
1−
fS
c
1−

=

where vRS = vR − vS is the velocity of the receiver relative to the source. Thus
the Doppler shift is

fR − f S = f D =

−vRS
fS
c

(2)

thus the frequency measured by a receiver moving away from a source will be less
than the frequency measured at the source, whereas the frequency measured by
a receiver moving towards a source will be greater than the frequency measured
at the source.

2

Continuous Wave Doppler Ultrasound

In the field of continuous wave Doppler ultrasound the source and receiver are
stationary. In addition the transmitting and receiving transducers may not be in
line 2 Let θt be the angle of the transmitter to the direction of motion and let θr
be the angle of the receiver to the direction of motion. Then the velocity of the
scatterer relative to the transmitter will be
v cos(θt )
and the velocity of the scatter relative to the receiver will be
v cos(θr )
2

Modern pulsed Doppler however uses the same transducer to transmit and receive.
transmitter

θt
receiver

θr

v
scatterer

The Doppler shift arising from a moving reflector/scatterer can be calculated by
assuming that
• the reflector/scatterer is a receiver moving away from the source with velocity v cos(θt ).
• that the receiver is moving away form the reflector/scatterer (source) with
velocity v cos(θr )
This is equivalent to the receiver moving away form the source with velocity
v cos(θt ) + v cos(θr ) even though both the receiver and transducer are stationary.
Thus from equation 2 we have

fS v
{cos(θt ) + cos(θr )}
c
θr + θ t
θr − θ t
2fS v
= −
cos
cos
c
2
2

fD = −

for θt ≈ θr we have

fD = −

2fS v
cos(θ)
c

(3)

where v cos(θ) is the velocity of the reflector/scatter relative to the receiver/transmitter.
This equation shows
• fD ∝ fS . When considerations of
• increased ultrasound attenuation with frequency
• increased back-scatter signal power with increasing frequency
• desired beam width
are taken into account fS is chosen to be 2 − 20 M Hz.
• fD ∝ v.
• fD ∝ 1/c.
• fD is dependent on the angles the transmitter and receiver beams make with
the velocity vector. In particular if the receiver and transmitter beams are
perpendicular to blood flow fD = 0.
• if v > 0 then fD < 0 and if v < 0 then fD > 0.

3

The Continuous Wave Doppler Instrument

3.1

Basis of operation

This section outlines the basis of the instrumentation required to detect Doppler
shifts in received ultrasound. Let the transmitted signal be of the form
xt (t) = ξt cos(ωS t)
and the corresponding signal received from one scatter be given as
xr (t) = ξr cos([ωS + ωD ]t + θ1 )
where
• ωS = 2πfS
• ωR = 2πfR
• θ1 is a phase term dependent on the distance of the scatterer from the
transducer and phase shifts produced within the receiver.
These two signals can be electronically multiplied together to give
xt (t)xr (t) = ξt ξr cos(ωS t) cos([ωS + ωD ]t + θ1 )
ξt ξr
{cos(ωD t + θ1 ) + cos([2ωS + ωD ]t + θ1 )}
=
2

(4)

This resulting signal is then low-pass filtered to remove the 2fS source frequency
leaving the Doppler signal

xD (t) =

ξt ξr
cos(ωD t + θ1 )
2

(5)

However further analogue signal processing may be required because the received
ultrasound signal also consists of reflected ultrasound of much greater amplitude
(≥ 40 − 50dB than backscattered signal from moving scatterer eg blood). Such
reflected ultrasound exhibits a low frequency Doppler shift because of movement
of the reflecting tissues eg. pulsating arteries and movement of the probe (if
hand-held). For this reason some form of high-pass filtering may be required
to remove this artefact. Such a procedure will unavoidably lose low frequency
Doppler signals from slowly moving blood which may be of clinical significance.

3.2

Discrimination of the direction of flow

The Doppler instrument described so far is unable to provide us with any information regarding the direction of motion. In instances where Doppler ultrasound
is used to assess blood flow the direction of blood flow may have diagnostic
significance. For example, in veins with incompetent valves or A-V malformations/fistulas. The directional information can be preserved in a number of ways
• side-band filtering
• offset carrier demodulation
• in-phase/quadrature demodulation
We will consider each of these techniques in turn. In the descriptions that follow
it must be remembered that
• ωD > 0 implies that velocity vector components along the beam are directed
towards the probe.
• ωD < 0 implies that velocity vector components along the beam are directed
away from the probe.
oscillator

RF amplifier

mixer

doppler probe

bandpass filter

frequency meter

blood vessel

audio amplifier

chart recorder

loudspeaker
headphones

Generic continuous wave Doppler instrumentation

3.2.1

Side-band filtering

This method is probably the simplest. The received rf signal is passed to two
filters, one passing frequencies over the range ωS < ω < ωS + ωm and the other
passing frequencies over the range ωS − ωm < ω < ωS . The output of each filter
passes to a multiplier and bandpass filter as before.

3.2.2

Offset carrier demodulation

In this method of determining the direction of flow the received signal is multiplied
by a reference signal ω1 + ωS . Thus as before the received signal is given by
xr (t) = ξr cos([ωS + ωD ]t + θ1 )
ωs

bandpass filter

audio
bandpass filter

+ve shifted doppler

audio
bandpass filter

(ω s,ω s+ ω m
)

-ve shifted doppler

rf in

bandpass filter

(ω s− ω m, ω s)

Side-band filtering

the reference signal is given by
x1 (t) = ξ1 cos([ωS + ω1 ]t)
Multiplying these two signals together gives

x1 (t)xr (t) =

ξ1 ξr
{cos([ω1 + ωD ]t + θ1 ) + cos([2ωS + ω1 + ωD ]t + θ1 )}
2

where ω1 is chosen such that ω1 ≥ |ωD,max |. As before this multiplied signal is
low pass filtered to remove the > 2ωS component. Thus

ω1 + ωD > ω1 +ve shifted doppler
ω1 + ωD < ω1 -ve shifted doppler
Note our tissue movement rejection filter is now a band-stop filter with a centre
frequency of ω1 .
3.2.3

In-phase/quadrature demodulation

The received signal is passed to two separate multipliers, one, the in phase reference, multiplies the signal by
reference signal

(ω s+ ω m
)

amplifier,
rf in

bandpass filter,

doppler shifted signal

notch filter

Offset carrier demodualtion

xip (t) = ξt cos(ωS t)
whereas the second, a +π/2 phase-shifted reference, multiplies the signal by

xps (t) = ξt cos(ωS t + π/2)
= −ξt sin(ωS t)
The in-phase signal, i(t), is given as before, as

i(t) = xr (t)xip (t)
ξr ξt
{cos(ωD t + θ1 ) + cos([2ωS + ωD ]t + θ1 )}
=
2
and the quadrature phase signal , q(t), is given by

q(t) = xr (t)xps (t)
= −ξr ξt sin(ωS t) cos([ωS + ωD ]t + θ1 )
ξr ξt
=
{sin(ωD t + θ1 ) − sin([2ωS + ωD ]t + θ1 )}
2
Both i(t) and q(t) are band-pass filtered and amplified as before to give
if (t) = cos(ωD t + θ1 )
qf (t) = sin(ωD t + θ1 )
The direction of the Doppler shift, and hence the direction of flow, is determined
by noting the phase relationship between if (t) and qf (t), i.e
• ωD > 0 then qf (t) is π/2 phase retarded with respect to if (t).
• ωD < 0 then qf (t) is π/2 phase advanced with respect to if (t).
reference signal

(ω s)

audio amplifier,
rf in
bandpass filter

i f (t)
(in phase)

+π/2

doppler signals

audio amplifier,
bandpass filter

q f (t)
(quadrature)

In-phase/quadrature demodulation

4

Pulsed Doppler Flow Detectors

There are problems associated with conventional continuous wave (CW) Doppler
instrumentation, particularly when used as a flow detector. The most important
one being that CW is unable to provide range resolution. In other words CW
is not able to separate Doppler signals arising from different points along the
transmitted ultrasound beam. Thus if two blood vessels intersect the ultrasonic
beam it is not possible to separate velocities at the different points along the
beam. The use of Pulsed Doppler is able to overcome this problem. The
significant differences between CW Doppler and Pulsed Doppler are
• a single transducer is used for transmission and reception as transmission
and reception are separated in time.
• pulsed Doppler is often incorporated as an additional signal processing step
in conventional pulse echo ultrasound (often known as duplex scanning).
• periodic bursts of ultrasound (e.g a few cycles) are used.
• pulsed Doppler in general is only sensitive to flow within a region termed
the sampling volume.
Range resolution in pulsed Doppler is achieved by transmitting a short burst
of ultrasound. Following the burst the received signal is mixed with a delayed
version of the transmitted burst as a reference signal. The transit time of the
transmitted pulse to the region of interest and back again is equal to this delay.
Thus the sampling volume can be moved to different positions along the beam by
altering this delay. The implications of this are clear: flow at different depths or
at different points within a vessel can be selectively monitored. The width of the
sampling volume will be proportional to the width of the transmitted ultrasound
beam, whereas the length of this sampling volume will be proportional to the
duration of the transmitted burst of ultrasound.

5

References

Evans D H. Doppler Ultrasound: Physics, Instrumentation and Clinical Applications. Wiley, Chichester. 1989.
Hill C R (ed). Physical Principles of Medical Ultrasonics. Ellis Horwood, Chichester. 1986.
Webb S (ed). The Physics of Medical Imaging. IOP Publishing, Bristol. 1992.
pp 319-388.

Weitere ähnliche Inhalte

Was ist angesagt?

Was ist angesagt? (19)

Doppler Ultrasonography And Advancements in USG
Doppler Ultrasonography And Advancements in USGDoppler Ultrasonography And Advancements in USG
Doppler Ultrasonography And Advancements in USG
 
Doppler effect experiment and applications
Doppler effect experiment and applicationsDoppler effect experiment and applications
Doppler effect experiment and applications
 
16 the doppler effect
16 the doppler effect16 the doppler effect
16 the doppler effect
 
Doppler effect
Doppler effectDoppler effect
Doppler effect
 
Doppler effect
Doppler effectDoppler effect
Doppler effect
 
Doppler effect
Doppler effectDoppler effect
Doppler effect
 
Sonar Principles Asw Analysis
Sonar Principles Asw AnalysisSonar Principles Asw Analysis
Sonar Principles Asw Analysis
 
Doppler
DopplerDoppler
Doppler
 
The Doppler Effect: Classroom example!
The Doppler Effect: Classroom example! The Doppler Effect: Classroom example!
The Doppler Effect: Classroom example!
 
Doppler artefact (1)
Doppler artefact (1)Doppler artefact (1)
Doppler artefact (1)
 
Doppler affect for Sound
Doppler affect for SoundDoppler affect for Sound
Doppler affect for Sound
 
The Doppler Effect
The Doppler EffectThe Doppler Effect
The Doppler Effect
 
Doppler us (3)
Doppler us (3)Doppler us (3)
Doppler us (3)
 
Sonar application (DSP)
Sonar application (DSP)Sonar application (DSP)
Sonar application (DSP)
 
ppt on radar system
 ppt on radar system ppt on radar system
ppt on radar system
 
Doppler effect lesson slides
Doppler effect lesson slidesDoppler effect lesson slides
Doppler effect lesson slides
 
Doppler effect and spectroscopy
Doppler effect and spectroscopyDoppler effect and spectroscopy
Doppler effect and spectroscopy
 
Doppler us (2)
Doppler us (2)Doppler us (2)
Doppler us (2)
 
SONAR
SONARSONAR
SONAR
 

Andere mochten auch

Ultrasound imaging
Ultrasound imagingUltrasound imaging
Ultrasound imagingNIVETA SINGH
 
Principles of Doppler ultrasound
Principles of Doppler ultrasoundPrinciples of Doppler ultrasound
Principles of Doppler ultrasoundSamir Haffar
 
Renal Tumour Angiomyolipoma - Bizarre Presentation
Renal Tumour Angiomyolipoma - Bizarre PresentationRenal Tumour Angiomyolipoma - Bizarre Presentation
Renal Tumour Angiomyolipoma - Bizarre PresentationSanjoy Sanyal
 
Chapter 5 presentation
Chapter 5 presentationChapter 5 presentation
Chapter 5 presentationssulit1
 
What is a doppler ultrasound
What is a doppler ultrasoundWhat is a doppler ultrasound
What is a doppler ultrasoundBhakti Stm
 
Renal calculli Veeresh VG RN
Renal calculli Veeresh VG RNRenal calculli Veeresh VG RN
Renal calculli Veeresh VG RNveereshvg
 
renal cell carcinoma radiology
renal cell carcinoma radiologyrenal cell carcinoma radiology
renal cell carcinoma radiologydocaashishgupt
 
Basic Interactions Between X Rays and Matter
Basic Interactions Between X Rays and MatterBasic Interactions Between X Rays and Matter
Basic Interactions Between X Rays and Mattersofiya modak
 
Diagnostic Imaging of Congenital Renal Anomalies
Diagnostic Imaging of Congenital Renal AnomaliesDiagnostic Imaging of Congenital Renal Anomalies
Diagnostic Imaging of Congenital Renal AnomaliesMohamed M.A. Zaitoun
 
Primary bone tumors
Primary bone tumorsPrimary bone tumors
Primary bone tumorsDpt Memon
 
PRINCIPLE OF ULTRAOUND
PRINCIPLE OF ULTRAOUNDPRINCIPLE OF ULTRAOUND
PRINCIPLE OF ULTRAOUNDhanisahwarrior
 
Renal Cancers Rationale
Renal Cancers RationaleRenal Cancers Rationale
Renal Cancers Rationalefondas vakalis
 
physical interaction of x ray with matter
physical interaction of x ray with matter physical interaction of x ray with matter
physical interaction of x ray with matter charusmita chaudhary
 
MR Imaging of shoulder and knee joints
MR Imaging of shoulder and knee jointsMR Imaging of shoulder and knee joints
MR Imaging of shoulder and knee jointsSahil Chaudhry
 

Andere mochten auch (20)

Doppler Physics
Doppler PhysicsDoppler Physics
Doppler Physics
 
Ultrasound imaging
Ultrasound imagingUltrasound imaging
Ultrasound imaging
 
Principles of Doppler ultrasound
Principles of Doppler ultrasoundPrinciples of Doppler ultrasound
Principles of Doppler ultrasound
 
Renal Tumour Angiomyolipoma - Bizarre Presentation
Renal Tumour Angiomyolipoma - Bizarre PresentationRenal Tumour Angiomyolipoma - Bizarre Presentation
Renal Tumour Angiomyolipoma - Bizarre Presentation
 
Chapter 5 presentation
Chapter 5 presentationChapter 5 presentation
Chapter 5 presentation
 
What is a doppler ultrasound
What is a doppler ultrasoundWhat is a doppler ultrasound
What is a doppler ultrasound
 
Ideal radiograph
Ideal radiographIdeal radiograph
Ideal radiograph
 
Renal calculli Veeresh VG RN
Renal calculli Veeresh VG RNRenal calculli Veeresh VG RN
Renal calculli Veeresh VG RN
 
renal cell carcinoma radiology
renal cell carcinoma radiologyrenal cell carcinoma radiology
renal cell carcinoma radiology
 
Basic Interactions Between X Rays and Matter
Basic Interactions Between X Rays and MatterBasic Interactions Between X Rays and Matter
Basic Interactions Between X Rays and Matter
 
Diagnostic Imaging of Congenital Renal Anomalies
Diagnostic Imaging of Congenital Renal AnomaliesDiagnostic Imaging of Congenital Renal Anomalies
Diagnostic Imaging of Congenital Renal Anomalies
 
Primary bone tumors
Primary bone tumorsPrimary bone tumors
Primary bone tumors
 
Baca ct scan
Baca ct scanBaca ct scan
Baca ct scan
 
Basic of mri
Basic of mriBasic of mri
Basic of mri
 
PRINCIPLE OF ULTRAOUND
PRINCIPLE OF ULTRAOUNDPRINCIPLE OF ULTRAOUND
PRINCIPLE OF ULTRAOUND
 
Ideal radiography
Ideal radiographyIdeal radiography
Ideal radiography
 
Renal Cancers Rationale
Renal Cancers RationaleRenal Cancers Rationale
Renal Cancers Rationale
 
Mri 3
Mri 3Mri 3
Mri 3
 
physical interaction of x ray with matter
physical interaction of x ray with matter physical interaction of x ray with matter
physical interaction of x ray with matter
 
MR Imaging of shoulder and knee joints
MR Imaging of shoulder and knee jointsMR Imaging of shoulder and knee joints
MR Imaging of shoulder and knee joints
 

Ähnlich wie Doppler

Ähnlich wie Doppler (20)

Doppler radar
Doppler radarDoppler radar
Doppler radar
 
Doppler Effect
Doppler EffectDoppler Effect
Doppler Effect
 
Kanal wireless dan propagasi
Kanal wireless dan propagasiKanal wireless dan propagasi
Kanal wireless dan propagasi
 
14 doppler measurement
14 doppler measurement14 doppler measurement
14 doppler measurement
 
Ch16 ssm
Ch16 ssmCh16 ssm
Ch16 ssm
 
Rappaport Chapter5-smallscalefading.pdf
Rappaport Chapter5-smallscalefading.pdfRappaport Chapter5-smallscalefading.pdf
Rappaport Chapter5-smallscalefading.pdf
 
Small scale fading
Small scale fading Small scale fading
Small scale fading
 
Standing waves
Standing wavesStanding waves
Standing waves
 
Ofdm Detection on Umts Utra-Fdd up-Link and Implementation of the Modulator/ ...
Ofdm Detection on Umts Utra-Fdd up-Link and Implementation of the Modulator/ ...Ofdm Detection on Umts Utra-Fdd up-Link and Implementation of the Modulator/ ...
Ofdm Detection on Umts Utra-Fdd up-Link and Implementation of the Modulator/ ...
 
Ch 15 waves
Ch 15 wavesCh 15 waves
Ch 15 waves
 
Pulse Modulation ppt
Pulse Modulation pptPulse Modulation ppt
Pulse Modulation ppt
 
Chirp spread spectrum communication
Chirp spread spectrum communicationChirp spread spectrum communication
Chirp spread spectrum communication
 
fading channels
 fading channels fading channels
fading channels
 
Phys 101 lo3
Phys 101 lo3 Phys 101 lo3
Phys 101 lo3
 
A New Underwater Acoustic Navigation Method Based on the Doppler Principle
A New Underwater Acoustic Navigation Method Based on the Doppler PrincipleA New Underwater Acoustic Navigation Method Based on the Doppler Principle
A New Underwater Acoustic Navigation Method Based on the Doppler Principle
 
Beat
BeatBeat
Beat
 
wireless communications
wireless communications wireless communications
wireless communications
 
dmct-otfs lab.pptx
dmct-otfs lab.pptxdmct-otfs lab.pptx
dmct-otfs lab.pptx
 
RiseFalltime031114.pptx
RiseFalltime031114.pptxRiseFalltime031114.pptx
RiseFalltime031114.pptx
 
PresentationSAR
PresentationSARPresentationSAR
PresentationSAR
 

Kürzlich hochgeladen

Uneak White's Personal Brand Exploration Presentation
Uneak White's Personal Brand Exploration PresentationUneak White's Personal Brand Exploration Presentation
Uneak White's Personal Brand Exploration Presentationuneakwhite
 
JAJPUR CALL GIRL ❤ 82729*64427❤ CALL GIRLS IN JAJPUR ESCORTS
JAJPUR CALL GIRL ❤ 82729*64427❤ CALL GIRLS IN JAJPUR  ESCORTSJAJPUR CALL GIRL ❤ 82729*64427❤ CALL GIRLS IN JAJPUR  ESCORTS
JAJPUR CALL GIRL ❤ 82729*64427❤ CALL GIRLS IN JAJPUR ESCORTSkajalroy875762
 
Puri CALL GIRL ❤️8084732287❤️ CALL GIRLS IN ESCORT SERVICE WE ARW PROVIDING
Puri CALL GIRL ❤️8084732287❤️ CALL GIRLS IN ESCORT SERVICE WE ARW PROVIDINGPuri CALL GIRL ❤️8084732287❤️ CALL GIRLS IN ESCORT SERVICE WE ARW PROVIDING
Puri CALL GIRL ❤️8084732287❤️ CALL GIRLS IN ESCORT SERVICE WE ARW PROVIDINGpriyakumari801827
 
QSM Chap 10 Service Culture in Tourism and Hospitality Industry.pptx
QSM Chap 10 Service Culture in Tourism and Hospitality Industry.pptxQSM Chap 10 Service Culture in Tourism and Hospitality Industry.pptx
QSM Chap 10 Service Culture in Tourism and Hospitality Industry.pptxDitasDelaCruz
 
Quick Doctor In Kuwait +2773`7758`557 Kuwait Doha Qatar Dubai Abu Dhabi Sharj...
Quick Doctor In Kuwait +2773`7758`557 Kuwait Doha Qatar Dubai Abu Dhabi Sharj...Quick Doctor In Kuwait +2773`7758`557 Kuwait Doha Qatar Dubai Abu Dhabi Sharj...
Quick Doctor In Kuwait +2773`7758`557 Kuwait Doha Qatar Dubai Abu Dhabi Sharj...daisycvs
 
Escorts in Nungambakkam Phone 8250092165 Enjoy 24/7 Escort Service Enjoy Your...
Escorts in Nungambakkam Phone 8250092165 Enjoy 24/7 Escort Service Enjoy Your...Escorts in Nungambakkam Phone 8250092165 Enjoy 24/7 Escort Service Enjoy Your...
Escorts in Nungambakkam Phone 8250092165 Enjoy 24/7 Escort Service Enjoy Your...meghakumariji156
 
Only Cash On Delivery Call Girls In Sikandarpur Gurgaon ❤️8448577510 ⊹Escorts...
Only Cash On Delivery Call Girls In Sikandarpur Gurgaon ❤️8448577510 ⊹Escorts...Only Cash On Delivery Call Girls In Sikandarpur Gurgaon ❤️8448577510 ⊹Escorts...
Only Cash On Delivery Call Girls In Sikandarpur Gurgaon ❤️8448577510 ⊹Escorts...lizamodels9
 
KALYANI 💋 Call Girl 9827461493 Call Girls in Escort service book now
KALYANI 💋 Call Girl 9827461493 Call Girls in  Escort service book nowKALYANI 💋 Call Girl 9827461493 Call Girls in  Escort service book now
KALYANI 💋 Call Girl 9827461493 Call Girls in Escort service book nowkapoorjyoti4444
 
Berhampur CALL GIRL❤7091819311❤CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDING
Berhampur CALL GIRL❤7091819311❤CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDINGBerhampur CALL GIRL❤7091819311❤CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDING
Berhampur CALL GIRL❤7091819311❤CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDINGpr788182
 
obat aborsi bandung wa 081336238223 jual obat aborsi cytotec asli di bandung9...
obat aborsi bandung wa 081336238223 jual obat aborsi cytotec asli di bandung9...obat aborsi bandung wa 081336238223 jual obat aborsi cytotec asli di bandung9...
obat aborsi bandung wa 081336238223 jual obat aborsi cytotec asli di bandung9...yulianti213969
 
Falcon Invoice Discounting: Empowering Your Business Growth
Falcon Invoice Discounting: Empowering Your Business GrowthFalcon Invoice Discounting: Empowering Your Business Growth
Falcon Invoice Discounting: Empowering Your Business GrowthFalcon investment
 
Katrina Personal Brand Project and portfolio 1
Katrina Personal Brand Project and portfolio 1Katrina Personal Brand Project and portfolio 1
Katrina Personal Brand Project and portfolio 1kcpayne
 
Getting Real with AI - Columbus DAW - May 2024 - Nick Woo from AlignAI
Getting Real with AI - Columbus DAW - May 2024 - Nick Woo from AlignAIGetting Real with AI - Columbus DAW - May 2024 - Nick Woo from AlignAI
Getting Real with AI - Columbus DAW - May 2024 - Nick Woo from AlignAITim Wilson
 
UAE Bur Dubai Call Girls ☏ 0564401582 Call Girl in Bur Dubai
UAE Bur Dubai Call Girls ☏ 0564401582 Call Girl in Bur DubaiUAE Bur Dubai Call Girls ☏ 0564401582 Call Girl in Bur Dubai
UAE Bur Dubai Call Girls ☏ 0564401582 Call Girl in Bur Dubaijaehdlyzca
 
Putting the SPARK into Virtual Training.pptx
Putting the SPARK into Virtual Training.pptxPutting the SPARK into Virtual Training.pptx
Putting the SPARK into Virtual Training.pptxCynthia Clay
 
PARK STREET 💋 Call Girl 9827461493 Call Girls in Escort service book now
PARK STREET 💋 Call Girl 9827461493 Call Girls in  Escort service book nowPARK STREET 💋 Call Girl 9827461493 Call Girls in  Escort service book now
PARK STREET 💋 Call Girl 9827461493 Call Girls in Escort service book nowkapoorjyoti4444
 
Berhampur 70918*19311 CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDING
Berhampur 70918*19311 CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDINGBerhampur 70918*19311 CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDING
Berhampur 70918*19311 CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDINGpr788182
 
The Abortion pills for sale in Qatar@Doha [+27737758557] []Deira Dubai Kuwait
The Abortion pills for sale in Qatar@Doha [+27737758557] []Deira Dubai KuwaitThe Abortion pills for sale in Qatar@Doha [+27737758557] []Deira Dubai Kuwait
The Abortion pills for sale in Qatar@Doha [+27737758557] []Deira Dubai Kuwaitdaisycvs
 
Challenges and Opportunities: A Qualitative Study on Tax Compliance in Pakistan
Challenges and Opportunities: A Qualitative Study on Tax Compliance in PakistanChallenges and Opportunities: A Qualitative Study on Tax Compliance in Pakistan
Challenges and Opportunities: A Qualitative Study on Tax Compliance in Pakistanvineshkumarsajnani12
 

Kürzlich hochgeladen (20)

Uneak White's Personal Brand Exploration Presentation
Uneak White's Personal Brand Exploration PresentationUneak White's Personal Brand Exploration Presentation
Uneak White's Personal Brand Exploration Presentation
 
JAJPUR CALL GIRL ❤ 82729*64427❤ CALL GIRLS IN JAJPUR ESCORTS
JAJPUR CALL GIRL ❤ 82729*64427❤ CALL GIRLS IN JAJPUR  ESCORTSJAJPUR CALL GIRL ❤ 82729*64427❤ CALL GIRLS IN JAJPUR  ESCORTS
JAJPUR CALL GIRL ❤ 82729*64427❤ CALL GIRLS IN JAJPUR ESCORTS
 
Puri CALL GIRL ❤️8084732287❤️ CALL GIRLS IN ESCORT SERVICE WE ARW PROVIDING
Puri CALL GIRL ❤️8084732287❤️ CALL GIRLS IN ESCORT SERVICE WE ARW PROVIDINGPuri CALL GIRL ❤️8084732287❤️ CALL GIRLS IN ESCORT SERVICE WE ARW PROVIDING
Puri CALL GIRL ❤️8084732287❤️ CALL GIRLS IN ESCORT SERVICE WE ARW PROVIDING
 
QSM Chap 10 Service Culture in Tourism and Hospitality Industry.pptx
QSM Chap 10 Service Culture in Tourism and Hospitality Industry.pptxQSM Chap 10 Service Culture in Tourism and Hospitality Industry.pptx
QSM Chap 10 Service Culture in Tourism and Hospitality Industry.pptx
 
Quick Doctor In Kuwait +2773`7758`557 Kuwait Doha Qatar Dubai Abu Dhabi Sharj...
Quick Doctor In Kuwait +2773`7758`557 Kuwait Doha Qatar Dubai Abu Dhabi Sharj...Quick Doctor In Kuwait +2773`7758`557 Kuwait Doha Qatar Dubai Abu Dhabi Sharj...
Quick Doctor In Kuwait +2773`7758`557 Kuwait Doha Qatar Dubai Abu Dhabi Sharj...
 
Escorts in Nungambakkam Phone 8250092165 Enjoy 24/7 Escort Service Enjoy Your...
Escorts in Nungambakkam Phone 8250092165 Enjoy 24/7 Escort Service Enjoy Your...Escorts in Nungambakkam Phone 8250092165 Enjoy 24/7 Escort Service Enjoy Your...
Escorts in Nungambakkam Phone 8250092165 Enjoy 24/7 Escort Service Enjoy Your...
 
Only Cash On Delivery Call Girls In Sikandarpur Gurgaon ❤️8448577510 ⊹Escorts...
Only Cash On Delivery Call Girls In Sikandarpur Gurgaon ❤️8448577510 ⊹Escorts...Only Cash On Delivery Call Girls In Sikandarpur Gurgaon ❤️8448577510 ⊹Escorts...
Only Cash On Delivery Call Girls In Sikandarpur Gurgaon ❤️8448577510 ⊹Escorts...
 
HomeRoots Pitch Deck | Investor Insights | April 2024
HomeRoots Pitch Deck | Investor Insights | April 2024HomeRoots Pitch Deck | Investor Insights | April 2024
HomeRoots Pitch Deck | Investor Insights | April 2024
 
KALYANI 💋 Call Girl 9827461493 Call Girls in Escort service book now
KALYANI 💋 Call Girl 9827461493 Call Girls in  Escort service book nowKALYANI 💋 Call Girl 9827461493 Call Girls in  Escort service book now
KALYANI 💋 Call Girl 9827461493 Call Girls in Escort service book now
 
Berhampur CALL GIRL❤7091819311❤CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDING
Berhampur CALL GIRL❤7091819311❤CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDINGBerhampur CALL GIRL❤7091819311❤CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDING
Berhampur CALL GIRL❤7091819311❤CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDING
 
obat aborsi bandung wa 081336238223 jual obat aborsi cytotec asli di bandung9...
obat aborsi bandung wa 081336238223 jual obat aborsi cytotec asli di bandung9...obat aborsi bandung wa 081336238223 jual obat aborsi cytotec asli di bandung9...
obat aborsi bandung wa 081336238223 jual obat aborsi cytotec asli di bandung9...
 
Falcon Invoice Discounting: Empowering Your Business Growth
Falcon Invoice Discounting: Empowering Your Business GrowthFalcon Invoice Discounting: Empowering Your Business Growth
Falcon Invoice Discounting: Empowering Your Business Growth
 
Katrina Personal Brand Project and portfolio 1
Katrina Personal Brand Project and portfolio 1Katrina Personal Brand Project and portfolio 1
Katrina Personal Brand Project and portfolio 1
 
Getting Real with AI - Columbus DAW - May 2024 - Nick Woo from AlignAI
Getting Real with AI - Columbus DAW - May 2024 - Nick Woo from AlignAIGetting Real with AI - Columbus DAW - May 2024 - Nick Woo from AlignAI
Getting Real with AI - Columbus DAW - May 2024 - Nick Woo from AlignAI
 
UAE Bur Dubai Call Girls ☏ 0564401582 Call Girl in Bur Dubai
UAE Bur Dubai Call Girls ☏ 0564401582 Call Girl in Bur DubaiUAE Bur Dubai Call Girls ☏ 0564401582 Call Girl in Bur Dubai
UAE Bur Dubai Call Girls ☏ 0564401582 Call Girl in Bur Dubai
 
Putting the SPARK into Virtual Training.pptx
Putting the SPARK into Virtual Training.pptxPutting the SPARK into Virtual Training.pptx
Putting the SPARK into Virtual Training.pptx
 
PARK STREET 💋 Call Girl 9827461493 Call Girls in Escort service book now
PARK STREET 💋 Call Girl 9827461493 Call Girls in  Escort service book nowPARK STREET 💋 Call Girl 9827461493 Call Girls in  Escort service book now
PARK STREET 💋 Call Girl 9827461493 Call Girls in Escort service book now
 
Berhampur 70918*19311 CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDING
Berhampur 70918*19311 CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDINGBerhampur 70918*19311 CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDING
Berhampur 70918*19311 CALL GIRLS IN ESCORT SERVICE WE ARE PROVIDING
 
The Abortion pills for sale in Qatar@Doha [+27737758557] []Deira Dubai Kuwait
The Abortion pills for sale in Qatar@Doha [+27737758557] []Deira Dubai KuwaitThe Abortion pills for sale in Qatar@Doha [+27737758557] []Deira Dubai Kuwait
The Abortion pills for sale in Qatar@Doha [+27737758557] []Deira Dubai Kuwait
 
Challenges and Opportunities: A Qualitative Study on Tax Compliance in Pakistan
Challenges and Opportunities: A Qualitative Study on Tax Compliance in PakistanChallenges and Opportunities: A Qualitative Study on Tax Compliance in Pakistan
Challenges and Opportunities: A Qualitative Study on Tax Compliance in Pakistan
 

Doppler

  • 1. HET408 Medical Imaging The Physics of Doppler Ultrasound
  • 2. 1 The Doppler Principle The basis of Doppler ultrasonography is the fact that reflected/scattered ultrasonic waves from a moving interface will undergo a frequency shift. In general the magnitude and the direction of this shift will provide information regarding the motion of this interface. To appreciate this very general fact we need to consider the relationship between the frequency, fS , of waves produced by a moving source and the frequency, fR , of the waves received by a moving receiver. For simplicity we shall assume that the source and receiver are moving along the same line. The argument that follows will generalise to three dimensions if wave speed is isotropic and the source produces spherical waves. At t = 0, let the source, S, and receiver, R, be separated by a distance d d S R v v S R At t = 0 let S emit a wave that reaches R at a time t later ct d v t R S R R’ In this time t the receiver will have moved a distance vR t and the wave, propagating with velocity c will have traveled a distance c t. Thus ct = d + vR t d t = c − vR or Now at time τ , the source will have moved a distance τ vS . Let the wave emitted at that instant be received at time t by R. In this time R would have traveled a total distance of vR t , and thus
  • 3. c(t’- τ) d v S v t’ R τ S S’ R R’’ c(t − τ ) = (d − vs τ ) + vR t d + (c − vs )τ t = c − vR or Thus for the receiver the interval between the waves has been τ =t −t= c − vS τ c − vR whereas for the source the interval between the waves has been τ . Now the number of waves emitted in τ by the source must be equal to the number of waves received by the receiver in τ i.e fR τ = f S τ Thus fR = For vS , vR c 1 c − vR fS c − vS (1) we can develop the following approximation, 1 − vR /c fS 1 − vS /c vR vS = 1− 1− c c fR = 1 this is reasonable as c v ≤ 2m s−1 −1 1500m s−1 and in Doppler measurements, e.g in blood flow,
  • 4. The last term on the right-hand side can be expanded using the binomial expansion (1 + x)n = 1 + nx + thus for x n(n − 1) 2 x + ··· 2! 1, higher order terms become unimportant and thus fR vR vS 1+ c c vRS 1− fS c 1− = where vRS = vR − vS is the velocity of the receiver relative to the source. Thus the Doppler shift is fR − f S = f D = −vRS fS c (2) thus the frequency measured by a receiver moving away from a source will be less than the frequency measured at the source, whereas the frequency measured by a receiver moving towards a source will be greater than the frequency measured at the source. 2 Continuous Wave Doppler Ultrasound In the field of continuous wave Doppler ultrasound the source and receiver are stationary. In addition the transmitting and receiving transducers may not be in line 2 Let θt be the angle of the transmitter to the direction of motion and let θr be the angle of the receiver to the direction of motion. Then the velocity of the scatterer relative to the transmitter will be v cos(θt ) and the velocity of the scatter relative to the receiver will be v cos(θr ) 2 Modern pulsed Doppler however uses the same transducer to transmit and receive.
  • 5. transmitter θt receiver θr v scatterer The Doppler shift arising from a moving reflector/scatterer can be calculated by assuming that • the reflector/scatterer is a receiver moving away from the source with velocity v cos(θt ). • that the receiver is moving away form the reflector/scatterer (source) with velocity v cos(θr ) This is equivalent to the receiver moving away form the source with velocity v cos(θt ) + v cos(θr ) even though both the receiver and transducer are stationary. Thus from equation 2 we have fS v {cos(θt ) + cos(θr )} c θr + θ t θr − θ t 2fS v = − cos cos c 2 2 fD = − for θt ≈ θr we have fD = − 2fS v cos(θ) c (3) where v cos(θ) is the velocity of the reflector/scatter relative to the receiver/transmitter. This equation shows • fD ∝ fS . When considerations of • increased ultrasound attenuation with frequency
  • 6. • increased back-scatter signal power with increasing frequency • desired beam width are taken into account fS is chosen to be 2 − 20 M Hz. • fD ∝ v. • fD ∝ 1/c. • fD is dependent on the angles the transmitter and receiver beams make with the velocity vector. In particular if the receiver and transmitter beams are perpendicular to blood flow fD = 0. • if v > 0 then fD < 0 and if v < 0 then fD > 0. 3 The Continuous Wave Doppler Instrument 3.1 Basis of operation This section outlines the basis of the instrumentation required to detect Doppler shifts in received ultrasound. Let the transmitted signal be of the form xt (t) = ξt cos(ωS t) and the corresponding signal received from one scatter be given as xr (t) = ξr cos([ωS + ωD ]t + θ1 ) where • ωS = 2πfS • ωR = 2πfR • θ1 is a phase term dependent on the distance of the scatterer from the transducer and phase shifts produced within the receiver. These two signals can be electronically multiplied together to give
  • 7. xt (t)xr (t) = ξt ξr cos(ωS t) cos([ωS + ωD ]t + θ1 ) ξt ξr {cos(ωD t + θ1 ) + cos([2ωS + ωD ]t + θ1 )} = 2 (4) This resulting signal is then low-pass filtered to remove the 2fS source frequency leaving the Doppler signal xD (t) = ξt ξr cos(ωD t + θ1 ) 2 (5) However further analogue signal processing may be required because the received ultrasound signal also consists of reflected ultrasound of much greater amplitude (≥ 40 − 50dB than backscattered signal from moving scatterer eg blood). Such reflected ultrasound exhibits a low frequency Doppler shift because of movement of the reflecting tissues eg. pulsating arteries and movement of the probe (if hand-held). For this reason some form of high-pass filtering may be required to remove this artefact. Such a procedure will unavoidably lose low frequency Doppler signals from slowly moving blood which may be of clinical significance. 3.2 Discrimination of the direction of flow The Doppler instrument described so far is unable to provide us with any information regarding the direction of motion. In instances where Doppler ultrasound is used to assess blood flow the direction of blood flow may have diagnostic significance. For example, in veins with incompetent valves or A-V malformations/fistulas. The directional information can be preserved in a number of ways • side-band filtering • offset carrier demodulation • in-phase/quadrature demodulation We will consider each of these techniques in turn. In the descriptions that follow it must be remembered that • ωD > 0 implies that velocity vector components along the beam are directed towards the probe. • ωD < 0 implies that velocity vector components along the beam are directed away from the probe.
  • 8. oscillator RF amplifier mixer doppler probe bandpass filter frequency meter blood vessel audio amplifier chart recorder loudspeaker headphones Generic continuous wave Doppler instrumentation 3.2.1 Side-band filtering This method is probably the simplest. The received rf signal is passed to two filters, one passing frequencies over the range ωS < ω < ωS + ωm and the other passing frequencies over the range ωS − ωm < ω < ωS . The output of each filter passes to a multiplier and bandpass filter as before. 3.2.2 Offset carrier demodulation In this method of determining the direction of flow the received signal is multiplied by a reference signal ω1 + ωS . Thus as before the received signal is given by xr (t) = ξr cos([ωS + ωD ]t + θ1 )
  • 9. ωs bandpass filter audio bandpass filter +ve shifted doppler audio bandpass filter (ω s,ω s+ ω m ) -ve shifted doppler rf in bandpass filter (ω s− ω m, ω s) Side-band filtering the reference signal is given by x1 (t) = ξ1 cos([ωS + ω1 ]t) Multiplying these two signals together gives x1 (t)xr (t) = ξ1 ξr {cos([ω1 + ωD ]t + θ1 ) + cos([2ωS + ω1 + ωD ]t + θ1 )} 2 where ω1 is chosen such that ω1 ≥ |ωD,max |. As before this multiplied signal is low pass filtered to remove the > 2ωS component. Thus ω1 + ωD > ω1 +ve shifted doppler ω1 + ωD < ω1 -ve shifted doppler Note our tissue movement rejection filter is now a band-stop filter with a centre frequency of ω1 . 3.2.3 In-phase/quadrature demodulation The received signal is passed to two separate multipliers, one, the in phase reference, multiplies the signal by
  • 10. reference signal (ω s+ ω m ) amplifier, rf in bandpass filter, doppler shifted signal notch filter Offset carrier demodualtion xip (t) = ξt cos(ωS t) whereas the second, a +π/2 phase-shifted reference, multiplies the signal by xps (t) = ξt cos(ωS t + π/2) = −ξt sin(ωS t) The in-phase signal, i(t), is given as before, as i(t) = xr (t)xip (t) ξr ξt {cos(ωD t + θ1 ) + cos([2ωS + ωD ]t + θ1 )} = 2 and the quadrature phase signal , q(t), is given by q(t) = xr (t)xps (t) = −ξr ξt sin(ωS t) cos([ωS + ωD ]t + θ1 ) ξr ξt = {sin(ωD t + θ1 ) − sin([2ωS + ωD ]t + θ1 )} 2 Both i(t) and q(t) are band-pass filtered and amplified as before to give
  • 11. if (t) = cos(ωD t + θ1 ) qf (t) = sin(ωD t + θ1 ) The direction of the Doppler shift, and hence the direction of flow, is determined by noting the phase relationship between if (t) and qf (t), i.e • ωD > 0 then qf (t) is π/2 phase retarded with respect to if (t). • ωD < 0 then qf (t) is π/2 phase advanced with respect to if (t). reference signal (ω s) audio amplifier, rf in bandpass filter i f (t) (in phase) +π/2 doppler signals audio amplifier, bandpass filter q f (t) (quadrature) In-phase/quadrature demodulation 4 Pulsed Doppler Flow Detectors There are problems associated with conventional continuous wave (CW) Doppler instrumentation, particularly when used as a flow detector. The most important one being that CW is unable to provide range resolution. In other words CW is not able to separate Doppler signals arising from different points along the transmitted ultrasound beam. Thus if two blood vessels intersect the ultrasonic beam it is not possible to separate velocities at the different points along the beam. The use of Pulsed Doppler is able to overcome this problem. The significant differences between CW Doppler and Pulsed Doppler are
  • 12. • a single transducer is used for transmission and reception as transmission and reception are separated in time. • pulsed Doppler is often incorporated as an additional signal processing step in conventional pulse echo ultrasound (often known as duplex scanning). • periodic bursts of ultrasound (e.g a few cycles) are used. • pulsed Doppler in general is only sensitive to flow within a region termed the sampling volume. Range resolution in pulsed Doppler is achieved by transmitting a short burst of ultrasound. Following the burst the received signal is mixed with a delayed version of the transmitted burst as a reference signal. The transit time of the transmitted pulse to the region of interest and back again is equal to this delay. Thus the sampling volume can be moved to different positions along the beam by altering this delay. The implications of this are clear: flow at different depths or at different points within a vessel can be selectively monitored. The width of the sampling volume will be proportional to the width of the transmitted ultrasound beam, whereas the length of this sampling volume will be proportional to the duration of the transmitted burst of ultrasound. 5 References Evans D H. Doppler Ultrasound: Physics, Instrumentation and Clinical Applications. Wiley, Chichester. 1989. Hill C R (ed). Physical Principles of Medical Ultrasonics. Ellis Horwood, Chichester. 1986. Webb S (ed). The Physics of Medical Imaging. IOP Publishing, Bristol. 1992. pp 319-388.