15. Physiology
• Aqueous humour
• Produced by ciliary body
• Carbonic anhydrase
• Drainage
• Venous channels
• SVC
15
16. Physiology
• Intraocular pressure (IOP)
• Range 10 - 20 mmHg
• Increases with age
• Direct correlation with axial length
• Main determinant is aqueous humour
16
17. Physiology
• Factors affecting IOP
• Arterial BP
• Auto-regulation
• Venous BP
• Valsalva, coughing, straining
• Partial pressures - CO , O
2 2
17
18. Events that Decrease
IOP
• IV anaesthetics
• Volatile anaesthetics
• Mannitol
• Timolol
18
19. Events that Increase
IOP
• Succinylcholine
• Direct laryngoscopy
• Hypoventilation
19
29. Factors that Influence
Choice of Anaesthesia
• Nature and duration of procedure
• Coagulation status
• Patient’s choice
• Ability to communicate and cooperate
29
34. Sub-Tenon’s Block
• Tenon’s capsule
• Dense fascial sheath surrounding the
globe and extraocular muscles from the
limbus to the optic nerve
34
35. Sub-Tenon’s Block
• Sensory block
• Short-ciliary nerves pass through Tenon’s
capsule to globe
• Akinesia
• Direct blockade of ant. nerve fibres as
they enter extra-ocular muscles
35
42. • Open Eye, Full Stomach
• Aspiration vs Blindness
• Strabismus surgery
• OCR
• MH
• PONV
42
43. • Intraocular Surgery
• Glaucoma, vitrectomy, cataracts
• IOP control
• Complete akinesia
• Continuation of miotics
• Provide an antiemetic effect
43
44. • Retinal Detachment Surgery
• SF injection for tamponade
6
• IV acetazolamide or mannitol
• Akinesia is not critical
44
46. • Regional Techniques
• Day stay surgery
• Better akinesia
• Less PONV
• Less effect on IOP
46
47. Evidence Based
Medicine
• Cochrane Reviews
• Peribulbar Vs. Retrobulbar
• Sub-Tenon’s Vs. Topical
47
48. Evidence Based
Medicine - CRTs
• General Vs Regional for Cataract Surgery
• Cognitive Function
• Perioperative MI
• Plasma catecholamine response
48
49. Summary
• Anatomy and Physiology
• Drug interactions
• Special Requirements
• Management of Specific Situations
49