Presentations from NW Russian regions – gaps and challenges, opportunities and strengths: Murmansk

1. «Thematic Program for Health Promotion
and prevention: Nordic – Russian
Cooperation on Antimicrobial Resistance
(AMR) Containment, 2019-2020»
Murmansk Region
February 28th, 2019

2. CENTRAL MULTIFUNCTION LABORATORY

3. EIGHT YEARS OF COOPERATION WITH
"RESEARCH INSTITUTE FOR ANTI-
MICROBIAL CHEMOTHERAPY",
SMOLENSK.
• PROFESSIONAL TRAINING
• PARTICIPATION IN THE FOLLOWING
PROGRAMS: AMR CONTROL IN THE
CENTRALASIA AND EASTERN EUROPE
(CAESAR) AND MULTICENTER
EPIDEMIOLOGICAL STUDY OF
NOSOCOMIAL INFECTIONS PATHOGENS
AB RESISTANCE OF (MARATHON)

4. EUCAST guidelines for detection of resistance mechanisms
and specific resistances of clinical and/or epidemiological
importance
www.eucast.org
1. Карбапенемазы у энтеробактерий
2. ESBL у энтеробактерий
3. AmpC у энтеробактерий
4. Р к метициллину у S. aureus
5. НЧ к гликопептидам у S. aureus
6. Р к гликопептидам у E. faecalis и
E. faecium
7. НЧ к пенициллину у S. pneumoniae

5. EXTERNAL QUALITY CONTROL OF
LABORATORY TESTS
• PARTICIPATION IN THE INTERLABORATORY
COMPARATIVE VALIDATIONS GUIDED BY THE
FEDERAL SYSTEM FOR EXTERNAL QUALITY
CONTROL (FSEQC) – ANNUALLY
• PARTICIPATION IN THE BRITISH
INTERNATIONAL PROGRAM FOR EXTERNAL
QUALITY CONTROL (UK NEQAS) - ANNUALLY

6. CENTRAL MULTIFUNCTION LABORATORY
Kola District
Murmansk
Severomorsk
Monchegorsk
Olenegorsk
Kovdor District
Pechenga
District

7. AUTOMATION AT THE STAGE OF INOCULATION

8. AUTOMATION AT THE STAGE OF
MICROORGANISM IDENTIFICATION

9. AUTOMATION AT THE STAGE OF RESULTS
INTERPRETING AND RECORDING
• COMPUTERIZED SYSTEM FOR
MICROBIOLOGICAL MONITORING:
ELECTRONIC DATABASE OF ISOLATED
MICROORGANISMS AND THEIR
ANTIBIOTIC SUSCEPTIBILITY PATTERN
(ANTIBIOGRAM) IS AVILABLE SINCE 2006.

10. 2017 – PCR METHOD FOR GENETIC RESISTANCE
MECHANISMS STUDIES WAS INTRODUCED

11. Chromogenic culture medium, 2018

12. ROLE OF MICROBIOLOGICAL
MONITORING
Bacteriological laboratory
Microorganism
sensitivity
AB resistance level AB activity Nosocomial strains
Attending
physician
Clinical
pharmacologist
Pharmacy Epidemiologist
Etiotropic therapy
AB therapy algorithm –
empiric treatment
AB procurement
Evaluation of epidemic alertness
signal symptoms, timely organized
isolation and restrictive measures

13. MOST CHALLENGING
”NOSOCOMIAL STRAINS"
• Enterococcus faecium
• Staphylococcus aureus (MRSA)
• Klebsiella pneumoniae
• Аcinetobacter baumannii
• Pseudomonas aeruginosae
• Enterobacter spp.

14. 2018
• GENETIC MONITORING OF Klebsiella
pneumoniae NOSOCOMIAL STRAINS WAS
CARRIED OUT: METALLO-Β-LACTAMASE
(NDM group) GENE WAS IDENTIFIED

15. PROSPECTS FOR INTERNATIONAL COOPERATION
1. EXPERIENCES IN IMPLEMENTATION OF INFECTIOUS CONTROL
STANDARDS
2. IMPROVING THE SYSTEM OF MICROBIOLOGICAL MONITORING
AND USE OFANTIBIOTICS FOR TREATMENT AND PREVENTION
3. IMPROVING HANDS HYGIENE SYSTEM (enhancement of medical staff
commitment to hands hygiene rules).
4. SHARING EXPERIENCES IN NURSING CARE SAFETY
TECHNOLOGIES IN ICU WARDS