Pharmaceutical packaging material

1. Prepared by :
Subash chandra chaudhary
Student of Universal college of medical
sciences ( 8th Batch B. Pharmacy)
Pharmaceutical Packaging Marials

2. Packaging
Packaging may be defined as the collection of different components
(e.g. bottle, vial, closure, cap, ampul, blister) which surround the
pharmaceutical product from the time of production until its use.
Why packaging?
 Packaging preserves the stability and quality of medicinal products
 Packaging protects them against all forms of spoilage and
tampering.
 Packaging provides certain level of elegance to the products to build
brand image.
 Packaging provides required safety mechanism to the consumers.

3. Stability aspects of packaging
Drug stability is the capacity of a drug product to remain
in the stable condition to ensure its identity, strength ,
quality and purity.
The packaging materials play vital role in the stability of
pharmaceutical products by following ways:
1. Protect the contents from environmental hazards:
packaging helps to protects the contents from
environmental hazards such as from Excessive light,
Excessive temperature, Extreme humidity, Aerial
oxidation , Particulate contamination and from
microbial contamination.

4. 2. Protect the contents from Mechanical hazards such
as:
a. Vibration : Usually due to transportation
b. Compression : Due to pressure applide during
stacking
c. Shock : Due to rapid retardation of product
contents
d. Puncture : Due to the penetration by sharp objects
e. Abrasion : Which may cause electrostatic effects

5. 3. By permitting the loss to its contents:
a. Protect the contents from both loss and gain of
water
b. Protect the contents from loss of volatile materials
c. Does not shed particles into the contents
d. Does not leach anything to the contents

6. Various factor influencing the choice of a
packaging material:
a. Physical Characteristics :
Packaging decisions are influenced by certain
physical characteristics of the product like
physical state , weight, stability, fragility and
rigidity. Packaging materials must not alter
the product tastes or odours. They must
meet applicable tamper-resistance
requirements.

7. b. Physiochemical characteristics:
• Certain physiochemical factors like the effects
of moisture, oxygen, light, flame and chemical
action on the product are very important
factors to be considered while making
decisions. Packaging materials must not be
reactive with the drug products through
chemical process such as hydrolysis, reduction
or photolysis phenomenon. They must be
non-toxic for drug products.

8. c. Economy:
There are a number of cases where the cost of
packaging is more than the cost of the content. The
rising cost of packaging has become a matter of
serious concern. Every effort should be made to
reduce the packaging costs as much as without
impairing the packaging requirements.
d. Legal factor :
Packaging materials must be ‘FDA’ approved.

9. e. Convenience:
Packaging should also necessarily possess the quality
of convenience from the point of view of consumers,
distributors and producer. A good packaging should
possess certain features like ease to open and close
the product and similarly ease to dispense, recycle ,
identify and handle the product. The packaging
materials are convenience to pack and display.
f. Miscellaneous factors:
packaging decisions may be influenced by the number
of socio-cultural factors. The growth of consumerism
in a number of countries suggests that packaging
decisions should be made with meticulous care.

10. Packaging equipment