1. CSIRO
HEALTH SCIENCES
& NUTRITION
WELCOME
Presented by: Poh Len Pek
Thursday, 20 May 2004

2.  Life Sciences research in:
 Prevention
 Diagnosis of diseases
 Treatment
CSIRO Health Sciences and Nutrition
Improvement of human well-being &
community health while enhancing the
competitiveness of the Australian food,
diagnostic and pharmaceutical
industries.
180 Scientists & staff
A$24m Research spend

3. Adelaide
 Gastrointestinal Health
 Clinical Nutrition
 Human Clinical Studies
 Consumer Science
 Diagnostic & Therapeutic
Technologies
 Protein & Receptor Structure and
Function
 Structure-based Drug Design
Melbourne
Disease Prevention Diagnosis & Treatment
Industries served: Food, Health, Diagnostic and Pharmaceutical
Disease Prevention  Diagnosis  Treatment

4.  Commercial Engagement
 Strategic Long Term Collaboration : Partnership
• Leveraged Funding, Co-investment
• Shared risks + rewards
  Fee For Service & Contract R&D
• Consulting & Projects
• Analytical Services
• Clinical Studies
• Market Rates
 Licensing
• Royalty on Sales

5. • Health effects
• Nutrient intake
trends
• Physiological and
biochemical
mechanisms
• Consumer science
• Psycho-social
determinates of
acceptance
Opportunity Validation
in vitro
in vivo
Validation
Human
Clinical
study
Consumer
Uptake
• Rapid method/
assays
• Biomarkers
• Bioavailability
• Efficacy testing
• Biomarkers
• Scientifically
accepted & well
designed
intervention
trials
• Partner in
NCEFF
• Drivers of
consumer
behaviour
• Product
acceptance
• Communication
strategies
• Regulatory
assessment
Health Sciences & Nutrition Capabilities
IDEA MARKET
Taking Health & Nutrition Products to Market

6. Leadership - Dr Katrine Baghurst
Professional team of 14 staff :
• Research scientists
• Psychologists
• Technicians
Consumer Science Team
Dr. Baghurst is Chair of the
National Health & Medical
Research Council (NHMRC) -
Dietary Guidelines Review
Working Party

7. Risk Perceptions of Consumer to Preventative Health
Strategies
Novel methods for assessing risk. Eg Cost benefit and
effectiveness of faecal occult blood testing in colorectal cancer
screening strategies
Consumer Acceptance of Functional and Novel Foods
Cognitive & Sensory Drivers
Marketing Strategy
Product Name, Positioning, Point of difference
Likely target market, Price Point
Marketing Communication Strategies
Target consumer markets, Community, Food Industry,
Health & Government
Consumer Science Capabilities & Research Focus

8.  Mood and Cognition
 Impact of nutrients, nutrient mix and food components
 Establishing and monitoring in Australia & Asia of:
Food and nutrient intake trends
Population health and nutritional status
Consumer attitudes & cross-cultural
differences
Determinants of consumer food choice
eg, Age & sensory factors affecting choice of meat
products that assisted in new meat product
development
Food availability, legislation and policy
 Opportunity identification for government or industry
Consumer Science Capabilities & Research Focus

9. Medical Director Leadership
- Dr Peter Clifton
Over 2 decades in clinical
substantiation studies
Trials from 10 to 120
(volunteer) subjects per trial
Clinical Research Unit Team
Professional team of 15 staff :
 Research scientists
 Dietitians
 Nurses
 Clinical Trial Managers
(GCP certified)
 Technical & Analytical staff

10. Excellence in Management of Human Intervention Trials
Clinical Research Unit - Substantiation
Substantiation of health benefits, claims
and potential of :
 Functional Foods
 Diets
 Food products /Ingredients
 Novel Foods
 Nutrients
 Supplements
 Complementary medicine
 Drugs (Phase II & III
– drug efficacy and dosage)

11. ►Knowledge of relevant and emerging biomarkers
►Trial management to Good
Clinical Practice
►Data management, analysis,
interpretation & publication
Clinical Research Unit Capabilities
►Indications for human interventions
►Ethics
►Cost effective trial design
►Communication strategies to scientific, media,
general public and food industry
►State-of-art instrumentations
eg. comprehensive cardio range

12. Impact of various dietary
composition on:
 Heart disease
 Hypertension
 Metabolic Syndrome
 Obesity
 Diabetes
 Glycemic Response
 Satiety
 Bowel Health
Clinical Research Unit -
Dietary Research Capabilities

13. Leadership - Dr David Topping
Professional team of 30
Research Scientists, Technical
and Analytical staff
Gastrointestinal Health Team
Capabilities
Dietary carbohydrates, fats
and other food components
on bowel health.

14.  In vitro, animal and human ileostomy studies on gut
health and function.
 Gut microflora composition and activity by measuring
SCFAs & other metabolites.
 Modelling carbohydrate (eg prebiotic and resistant
starch) effect on gut physiology and function using
novel and conventional bowel health biomarkers.
 Enhancement of mineral (Ca, Fe, Zn, Mg) absorption and
bioavailability in large intestine.
 Molecular microbiology and biomarkers.
Prebiotic, probiotic and synbiotic
New bowel health products
Gastrointestinal Health Research Focus & Capabilities

15. Gastrointestinal Health Research Focus & Capabilities
 Plant derived water soluble antioxidants/bioactives
for vascular function
 Screening assays for bioactive molecules
 Bioavailability of nutrients & phytochemicals
 Novel antimicrobial agents from biowaste

16. Your contact
Poh Len Pek
Business Development Manager
pohlen.pek@csiro.au
Tel: 08 8303 8893 (Adelaide)
03 9662 7117 (Parkville)
Mobile: 0417 007 118
For more information, see www.hsn.csiro.au
or contact: