This document summarizes a regional conference on investment and inclusive growth in the Middle East and North Africa focusing on small and medium enterprise (SME) policies. It notes that SMEs are important for inclusion, economic growth, and government revenues. SMEs account for a large percentage of jobs in the region but formal employment and new business creation in SMEs is relatively low compared to other regions. The document outlines main challenges for SMEs such as regulatory environments and access to financing, as well as opportunities like growing domestic markets. It recommends policies to improve the business climate, adopt comprehensive SME strategies, and strengthen regional cooperation and capacity building to better support SME development and growth.