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The UK NIHR Health Technology Co-operative (HTC) in
Mental Health and Neurodevelopmental Disorders
- ‘MindTech’
John Crowe1, C Hollis2, R Morriss2, MF Valstar3,
L Bai3, D Daley2, P Blanchfield3
1 Faculty

of Engineering, 2 Institute of Mental Health,
3 Computer Science

Med-e-Tel 2013

1
Med-e-Tel 2013

2
NIHR HTCs
“The aims of the NIHR Healthcare Technology Co-operatives (HTCs)
are to:
• act as a catalyst for NHS “pull” for the development of new
medical devices, healthcare technologies and technologydependent interventions
• focus on clinical areas and/or themes of high morbidity which
have high potential for improving quality of life of NHS patients
and improving the effectiveness of healthcare services that
support them
• work collaboratively with patients and patient groups, charities,
industry and academics.”
Med-e-Tel 2013

3
8 new HTCs launched : 2013 for 4 years
•
•
•
•
•
•
•
•

Chronic gastrointestinal (GI) disease
Brain injury
Cardiovascular disease
Devices for dignity (D4D)
Wound prevention & treatment
Colorectal therapies
Mental health & neurodevelopmental disorders
Trauma management
Med-e-Tel 2013

4
MindTech
NIHR HTC in Mental health & neurodevelopmental disorders

University of Nottingham Innovation Park
Med-e-Tel 2013

5
Why Mental Health?
• Huge economic cost to UK - £105bn per year

• Largest area of government health spending (13%)
• Little technological innovation
• Subjective clinical assessment dominates practice

• Lack of engagement with SMEs
• Strong public and patient involvement (PPI)

Med-e-Tel 2013

6
Med-e-Tel 2013

7
Clinical Landscape
• Mood Disorders
– Unipolar depression
– Bipolar depression

• Neurodevelopmental disorder
– Autism spectrum disorder
– Tourette syndrome
– Attention Deficit Hyperactivity Disorder (ADHD)
Med-e-Tel 2013

8
Current prevalence of disorders of the brain in Europe
Mental retardation

1.0

opiate dependence

0.4

OCD

GAD

0.7

Eating disorder

0.9

Cannabis dependence

1.0

1.7

Specific
phobia

Psychotic disorder

1.2

Personality dis.

1.3

6.4

PTSD

Social
phobia

2.3

2.0

Conduct disorder

Agoraphobia

3.0

Alcohol dependence

2.0

3.4

Somatoform disorders
ADHD

Panic
disorder

4.9

1.8

5.0

0

Dementia

4

8

12

5.4

Unipolar depression

6.9

Insomnia

7.0

Anxiety disorders

14.0
0

2

4

6

8

10

12

14

Wittchen et al 2011 European Neuropsychopharmacology
Med-e-Tel 2013

9
Bringing Partners Together
Nottinghamshire Healthcare Trust

NHS
ADDISS

IMH1
Computer
Science

Tourettes
Action

Patients
Clinicians
Medilink

HTC
University

Biomedical
Engineering

Academics

QbTech

Industry
TTO2

SMEs

BuddyApp

Buzz3D

Business
RedEmbedded
1: Institute of Mental Health
2: Technology Transfer Office

Med-e-Tel 2013

10
Technology Innovation Pipeline
Patients, Clinicians, NHS Trusts

Identifying Need

Implementation

Development

NICE/ HTA

NICE/ HTA

Academics & SMEs

Facial affect recognition

QbTest

RedEmbedded
BuddyApp

Automated tic monitoring

Med-e-Tel 2013

11
Personalised Ambient Monitoring (PAM)
User input:
• General health
questionnaires
• Mood selfassessment
Wearable Node
•Acceleration
•General light level
•Artificial light level
•Ambient sound
properties

GSM
location

GPS
module
XYZ
accelerometer

Internal
accelerometer

Bluetooth
Encounters*

- Bluetooth

- 3G / GPRS

- User input

Med-e-Tel 2013

-Internal

12
Identifying meaningful locations

Med-e-Tel 2013

13
Automated objective assessment of
mood and behaviour

Med-e-Tel 2013

14
Automatic tic monitoring & analysis
•
•
•
•

Face and expression recognition
Automatic eye blink detection
Hand and body tracking
Integration & tic data analysis

Med-e-Tel 2013

15
Games that engage
•
•
•
•

For diagnosis and treatment
Work with ADHD children shows they will engage with games
Games that treat and promote interaction with therapist
Playful environments to encourage young people to discuss
their emotional reactions

Med-e-Tel 2013

16
Qb Test: Objective Assessment of ADHD

• Computerised assessment of
attention and activity
• Supports clinical decision
making
• Provides patients with
objective reports on their
condition
Med-e-Tel 2013

17
Text messaging app to
support therapy

Diary:
SMS or web

Analysis tool

Goal
reminders

Med-e-Tel 2013

Appointment
prompts

18
Delivering
Remote
Care
Integration
Connecting people visually:
a key enabler in
remote care delivery

Med-e-Tel 2013

19
What can we offer ?
• Collaboration with SMEs & academics
•
•
•
•
•
•
•
•

Clinical expertise
Technology Trials
Patient Public Participation (PPI)
Early stage Health Economics
Advice on NICE assessment procedures
An understanding of clinical pathways
Advice on procurement procedures
Technological expertise & regulatory advice
Med-e-Tel 2013

20
Contact
Prinicipal Investigator
Prof Chris Hollis
chris.hollis@nottingham.ac.uk

Prof John Crowe
john.crowe@nottingham.ac.uk
Med-e-Tel 2013

21

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Introduction to MindTech - NIHR Health Technology Co-operative in mental health

  • 1. The UK NIHR Health Technology Co-operative (HTC) in Mental Health and Neurodevelopmental Disorders - ‘MindTech’ John Crowe1, C Hollis2, R Morriss2, MF Valstar3, L Bai3, D Daley2, P Blanchfield3 1 Faculty of Engineering, 2 Institute of Mental Health, 3 Computer Science Med-e-Tel 2013 1
  • 3. NIHR HTCs “The aims of the NIHR Healthcare Technology Co-operatives (HTCs) are to: • act as a catalyst for NHS “pull” for the development of new medical devices, healthcare technologies and technologydependent interventions • focus on clinical areas and/or themes of high morbidity which have high potential for improving quality of life of NHS patients and improving the effectiveness of healthcare services that support them • work collaboratively with patients and patient groups, charities, industry and academics.” Med-e-Tel 2013 3
  • 4. 8 new HTCs launched : 2013 for 4 years • • • • • • • • Chronic gastrointestinal (GI) disease Brain injury Cardiovascular disease Devices for dignity (D4D) Wound prevention & treatment Colorectal therapies Mental health & neurodevelopmental disorders Trauma management Med-e-Tel 2013 4
  • 5. MindTech NIHR HTC in Mental health & neurodevelopmental disorders University of Nottingham Innovation Park Med-e-Tel 2013 5
  • 6. Why Mental Health? • Huge economic cost to UK - £105bn per year • Largest area of government health spending (13%) • Little technological innovation • Subjective clinical assessment dominates practice • Lack of engagement with SMEs • Strong public and patient involvement (PPI) Med-e-Tel 2013 6
  • 8. Clinical Landscape • Mood Disorders – Unipolar depression – Bipolar depression • Neurodevelopmental disorder – Autism spectrum disorder – Tourette syndrome – Attention Deficit Hyperactivity Disorder (ADHD) Med-e-Tel 2013 8
  • 9. Current prevalence of disorders of the brain in Europe Mental retardation 1.0 opiate dependence 0.4 OCD GAD 0.7 Eating disorder 0.9 Cannabis dependence 1.0 1.7 Specific phobia Psychotic disorder 1.2 Personality dis. 1.3 6.4 PTSD Social phobia 2.3 2.0 Conduct disorder Agoraphobia 3.0 Alcohol dependence 2.0 3.4 Somatoform disorders ADHD Panic disorder 4.9 1.8 5.0 0 Dementia 4 8 12 5.4 Unipolar depression 6.9 Insomnia 7.0 Anxiety disorders 14.0 0 2 4 6 8 10 12 14 Wittchen et al 2011 European Neuropsychopharmacology Med-e-Tel 2013 9
  • 10. Bringing Partners Together Nottinghamshire Healthcare Trust NHS ADDISS IMH1 Computer Science Tourettes Action Patients Clinicians Medilink HTC University Biomedical Engineering Academics QbTech Industry TTO2 SMEs BuddyApp Buzz3D Business RedEmbedded 1: Institute of Mental Health 2: Technology Transfer Office Med-e-Tel 2013 10
  • 11. Technology Innovation Pipeline Patients, Clinicians, NHS Trusts Identifying Need Implementation Development NICE/ HTA NICE/ HTA Academics & SMEs Facial affect recognition QbTest RedEmbedded BuddyApp Automated tic monitoring Med-e-Tel 2013 11
  • 12. Personalised Ambient Monitoring (PAM) User input: • General health questionnaires • Mood selfassessment Wearable Node •Acceleration •General light level •Artificial light level •Ambient sound properties GSM location GPS module XYZ accelerometer Internal accelerometer Bluetooth Encounters* - Bluetooth - 3G / GPRS - User input Med-e-Tel 2013 -Internal 12
  • 14. Automated objective assessment of mood and behaviour Med-e-Tel 2013 14
  • 15. Automatic tic monitoring & analysis • • • • Face and expression recognition Automatic eye blink detection Hand and body tracking Integration & tic data analysis Med-e-Tel 2013 15
  • 16. Games that engage • • • • For diagnosis and treatment Work with ADHD children shows they will engage with games Games that treat and promote interaction with therapist Playful environments to encourage young people to discuss their emotional reactions Med-e-Tel 2013 16
  • 17. Qb Test: Objective Assessment of ADHD • Computerised assessment of attention and activity • Supports clinical decision making • Provides patients with objective reports on their condition Med-e-Tel 2013 17
  • 18. Text messaging app to support therapy Diary: SMS or web Analysis tool Goal reminders Med-e-Tel 2013 Appointment prompts 18
  • 19. Delivering Remote Care Integration Connecting people visually: a key enabler in remote care delivery Med-e-Tel 2013 19
  • 20. What can we offer ? • Collaboration with SMEs & academics • • • • • • • • Clinical expertise Technology Trials Patient Public Participation (PPI) Early stage Health Economics Advice on NICE assessment procedures An understanding of clinical pathways Advice on procurement procedures Technological expertise & regulatory advice Med-e-Tel 2013 20
  • 21. Contact Prinicipal Investigator Prof Chris Hollis chris.hollis@nottingham.ac.uk Prof John Crowe john.crowe@nottingham.ac.uk Med-e-Tel 2013 21