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Institute for Microbiology, Medical Faculty of Masaryk University  and St. Anna Faculty Hospital in Brno Miroslav Votava, Vladana Woznicová PATHOGENICITY AND VIRULENCE Lecture for 2nd-year students March 3 0 , 200 9
Pathogenicity  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Ecological remark ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Infection ,[object Object],[object Object],[object Object]
History of infectious diseases   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Koch´s postulates   ,[object Object],[object Object],[object Object],[object Object],[object Object]
Relationship between the microbe and the host   ,[object Object],[object Object],[object Object],[object Object],[object Object]
Pathogenicity ,[object Object],[object Object],[object Object]
Primary and opportune pathogens   ,[object Object],[object Object],[object Object],[object Object]
Natural and experimental pathogenicity   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Opportunistic pathogens – I   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
S. aureus  bacteria escaping destruction by human white blood cells   http://www3.niaid.nih.gov http://www.podiatrytoday.com
Opportunistic pathogens – II ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Virulence  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Attenuation   ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
  MICROBE     obligately   opportunistically Species:   pathogenic  pathogenic  non-pathogenic   Strain:   virulent  avirulent   Individual:  sensitive  nonspecifically unresponsive  or specifically immune Species:   susceptible  resistant HOST
Recommended reading material   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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07 pathogenicity and_virulence

  • 1. Institute for Microbiology, Medical Faculty of Masaryk University and St. Anna Faculty Hospital in Brno Miroslav Votava, Vladana Woznicová PATHOGENICITY AND VIRULENCE Lecture for 2nd-year students March 3 0 , 200 9
  • 2.
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  • 4.
  • 5.
  • 6.  
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.  
  • 13.
  • 14. S. aureus bacteria escaping destruction by human white blood cells http://www3.niaid.nih.gov http://www.podiatrytoday.com
  • 15.
  • 16.
  • 17.
  • 18.  
  • 19. MICROBE obligately opportunistically Species: pathogenic pathogenic non-pathogenic Strain: virulent avirulent Individual: sensitive nonspecifically unresponsive or specifically immune Species: susceptible resistant HOST
  • 20.