The European Mobile Laboratory (EMLab) Project 2012-2015 during the Ebola outbreak.

1. „Establishment of Mobile Laboratories up to
Risk Group 4 in combination with CBRN
Capacity Building in sub-Saharan Africa“
Funded by the European Commission,
Development and Cooperation Offi ce
European Mobile Laboratory
(EMLab) Project 2012–2015

2. Partners: BSL4 laboratories in Europe

3. 26. March 2014

6. Summary – EMLab units deployed for Ebola virus diagnostics
(10.000 samples tested)

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8. European Mobile Laboratory mission statistics, as per 31 October 2015

9. Operational research
• November 2014: Launch of EVIDENT project funded by European
Commission Horizon 2020 program emergency mechanism – research
arm of EMLab
– Correlates of protection at B and T cell level
– Immunopathology (role of dendritic and T cells in immunosuppression) and
biomarkers in EVD
– Sequencing (180 genomes + real-time in country sequencing)
• Support to projects of partners
– Favipiravir trail, Gueckedou (PCR and biochemistry)
– Favipiravir compassionate use, Coyah (PCR and biochem)
– Interferon trial, Coyah (PCR and biochem)
– Vaccine phase III trial, Coyah / Conakry
– Rapid diagnostic test validation for WHO, Freetown

10. MinION in Conakry for real-time sequencing
(15/04/2015) - follow-up and identifi cation of
transmission chains
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12. About 50 sequences generated so far
in Guinea to guide epidemiological
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13. Clinical Chemistry in Gueckedou 1
180 samples, values sorted from small to large
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14. Long-term Partnership and Capacity Building for Diagnostics
and Research on Viral Hemorrhagic Fevers in Africa
(Volkswagen Foundation, DFG Africa Initiative, EC)
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18. Critical role of the Nigerian mobile lab in EVD diagnostics in Nigeria, 2014
Deployment to Enugu, Enugu State
Deployment to Port Harcourt, River State

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23. Conclusions
• Rapid deployable capacity
• Operational research (diagnostics, clinical trails,
sequencing)
• Support to patient management (malaria, clinical
chemistry)
• Human resources and research/public health
infrastructures in Africa
• Biosecurity regulations may hamper response

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We are still looking for volunteers
to go to Guinea and Sierra Leone

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