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Nueva Clasificación ILAE 2010 Dr. Edgar Avalos Herrera Neurólogo Internista
The history of classification has rested largely upon astute observations and expert opinions. First published in 1960 and last updated officially in 1981 for seizures and 1989 for epilepsies, the ILAE classifications are based on concepts that, for the most part, predate modern neuroimaging, genomic technologies and concepts in molecular biology.
A primary motivation for revising the classification in the 2005–2009 Commission term and to continue revising it in the future is to bring epilepsy out of the shadows of expertopinion…
Of particular importance to practitioners, no changes are being made to the list of entities that have been recognized and which was updated in the 2006 Task force report (Engel, 2006)…
The 1989 classification was not a true scientific classification but rather an organization built on concepts which no longer correspond to or accurately describe our increasing knowledge of seizures and the epilepsies. Consequently, the current organization and the concepts on which it is based are being abandoned or revised...
The expert-opinion review process for “admitting” a syndrome to the list will need to be replaced by a system based upon objective analysis using robust statistical methods… …This will be required to validate currently accepted syndromes… …This is a process we intend to initiate in the upcoming years…
MODIFICACIONES A LA CLASIFICACIÓN 1981 Neonatal seizures are no longer regarded as a separate entity. Seizures in neonates can be classified within the proposed scheme.
MODIFICACIONES A LA CLASIFICACIÓN 1981 The previous subclassification of absence seizures has been simplified and altered. Myoclonic absence seizures and eyelid myoclonia are now recognized.
MODIFICACIONES A LA CLASIFICACIÓN 1981 Spasms were not explicitly acknowledged in the 1981 classification of seizures. They are now included.
MODIFICACIONES A LA CLASIFICACIÓN 1981 For focal seizures, the distinction between the different types (e.g., complex partial and simple partial) is eliminated.
MODIFICACIONES A LA CLASIFICACIÓN 1981 Myoclonicatonic (previously called ‘‘myoclonicastatic’’) seizures are now recognized.
Underlying type of cause (etiology) Instead of the terms idiopathic, symptomatic, and cryptogenic, the following three terms and their associated concepts are recommended: GENETIC STRUCTURAL / METABOLIC UNKNOWN CAUSE
Disease versus syndrome Although there is reason to distinguish the concepts of disease and syndrome, these terms are not consistently used in medicine. Ultimately, it was decided not to insist on the disease–syndrome distinction in referring to the epilepsies…
The terms ‘‘focal’’ and ‘‘generalized’’ The Commission felt that it was still of some pragmatic utility to maintain the terminology, although it was generally acknowledged that these terms likely did not represent a clear dichotomy.
The terms ‘‘simple’’ and ‘‘complex’’ This terminology was imprecise, as the terms were often misused or misunderstood.
The term ‘‘secondarily’’ generalized Is poorly understood and inconsistently used.
Reestablishing the concept of ‘‘electroclinical syndrome’’ An electroclinical syndrome, however, is a complex of clinical features, signs, and symptoms that together define a distinctive, recognizable clinical disorder.
Constellations There are a number of entities that are not exactly electroclinical syndromes in the same sense but which represent clinically distinctive constellations on the basis of specific lesions or other causes.
Constellations These are: Mesial temporal lobeepilepsy (withhippocampalsclerosis) … … …
Dimensions for classifying epilepsies and organizing information In referring to syndromes, the dichotomy of focal versus generalized will be abandoned.
CLASIFICACIÓN DE CRISIS EPILÉPTICAS 2010 CRISIS GENERALIZADAS Tónico-Clónicas Ausencias Típicas Atípicas Con CaracterísticasEspeciales AusenciasMioclónicas MiocloníasPalpebrales
CLASIFICACIÓN DE CRISIS EPILÉPTICAS 2010 CRISIS GENERALIZADAS Mioclónicas Mioclónicas Mioclónico-Atónicas Mioclónico-Tónicas Clónicas Tónicas Atónicas
CLASIFICACIÓN DE CRISIS EPILÉPTICAS 2010 CRISIS FOCALES ORIGEN DESCONOCIDO EspasmosEpilépticos
CLASIFICACIÓN DE SÍNDROMES ELECTROCLÍNICOS Y OTRAS EPILEPSIAS 2010 Período Neonatal Infancia Niñez Adolescente-Adulto Relaciónmenosespecífica con la edad
CLASIFICACIÓN DE SÍNDROMES ELECTROCLÍNICOS Y OTRAS EPILEPSIAS 2010 Constelaciones Mesial temporal lobe epilepsy with hippocampal sclerosis Epilepsias con causaestructural o metabólica SíndromesNeurocutáneos Epilepsias de causadesconocida Condiciones con crisis epilépticas no diagnosticadascomounaepilepsia per se Crisis Febriles
Other concepts and terms
G R A C I A S

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Nueva Clasificación ILAE 2010

  • 1. Nueva Clasificación ILAE 2010 Dr. Edgar Avalos Herrera Neurólogo Internista
  • 2.
  • 3.
  • 4.
  • 5.
  • 6. The history of classification has rested largely upon astute observations and expert opinions. First published in 1960 and last updated officially in 1981 for seizures and 1989 for epilepsies, the ILAE classifications are based on concepts that, for the most part, predate modern neuroimaging, genomic technologies and concepts in molecular biology.
  • 7. A primary motivation for revising the classification in the 2005–2009 Commission term and to continue revising it in the future is to bring epilepsy out of the shadows of expertopinion…
  • 8. Of particular importance to practitioners, no changes are being made to the list of entities that have been recognized and which was updated in the 2006 Task force report (Engel, 2006)…
  • 9. The 1989 classification was not a true scientific classification but rather an organization built on concepts which no longer correspond to or accurately describe our increasing knowledge of seizures and the epilepsies. Consequently, the current organization and the concepts on which it is based are being abandoned or revised...
  • 10. The expert-opinion review process for “admitting” a syndrome to the list will need to be replaced by a system based upon objective analysis using robust statistical methods… …This will be required to validate currently accepted syndromes… …This is a process we intend to initiate in the upcoming years…
  • 11. MODIFICACIONES A LA CLASIFICACIÓN 1981 Neonatal seizures are no longer regarded as a separate entity. Seizures in neonates can be classified within the proposed scheme.
  • 12. MODIFICACIONES A LA CLASIFICACIÓN 1981 The previous subclassification of absence seizures has been simplified and altered. Myoclonic absence seizures and eyelid myoclonia are now recognized.
  • 13. MODIFICACIONES A LA CLASIFICACIÓN 1981 Spasms were not explicitly acknowledged in the 1981 classification of seizures. They are now included.
  • 14. MODIFICACIONES A LA CLASIFICACIÓN 1981 For focal seizures, the distinction between the different types (e.g., complex partial and simple partial) is eliminated.
  • 15. MODIFICACIONES A LA CLASIFICACIÓN 1981 Myoclonicatonic (previously called ‘‘myoclonicastatic’’) seizures are now recognized.
  • 16. Underlying type of cause (etiology) Instead of the terms idiopathic, symptomatic, and cryptogenic, the following three terms and their associated concepts are recommended: GENETIC STRUCTURAL / METABOLIC UNKNOWN CAUSE
  • 17. Disease versus syndrome Although there is reason to distinguish the concepts of disease and syndrome, these terms are not consistently used in medicine. Ultimately, it was decided not to insist on the disease–syndrome distinction in referring to the epilepsies…
  • 18. The terms ‘‘focal’’ and ‘‘generalized’’ The Commission felt that it was still of some pragmatic utility to maintain the terminology, although it was generally acknowledged that these terms likely did not represent a clear dichotomy.
  • 19. The terms ‘‘simple’’ and ‘‘complex’’ This terminology was imprecise, as the terms were often misused or misunderstood.
  • 20. The term ‘‘secondarily’’ generalized Is poorly understood and inconsistently used.
  • 21. Reestablishing the concept of ‘‘electroclinical syndrome’’ An electroclinical syndrome, however, is a complex of clinical features, signs, and symptoms that together define a distinctive, recognizable clinical disorder.
  • 22. Constellations There are a number of entities that are not exactly electroclinical syndromes in the same sense but which represent clinically distinctive constellations on the basis of specific lesions or other causes.
  • 23. Constellations These are: Mesial temporal lobeepilepsy (withhippocampalsclerosis) … … …
  • 24. Dimensions for classifying epilepsies and organizing information In referring to syndromes, the dichotomy of focal versus generalized will be abandoned.
  • 25. CLASIFICACIÓN DE CRISIS EPILÉPTICAS 2010 CRISIS GENERALIZADAS Tónico-Clónicas Ausencias Típicas Atípicas Con CaracterísticasEspeciales AusenciasMioclónicas MiocloníasPalpebrales
  • 26. CLASIFICACIÓN DE CRISIS EPILÉPTICAS 2010 CRISIS GENERALIZADAS Mioclónicas Mioclónicas Mioclónico-Atónicas Mioclónico-Tónicas Clónicas Tónicas Atónicas
  • 27. CLASIFICACIÓN DE CRISIS EPILÉPTICAS 2010 CRISIS FOCALES ORIGEN DESCONOCIDO EspasmosEpilépticos
  • 28. CLASIFICACIÓN DE SÍNDROMES ELECTROCLÍNICOS Y OTRAS EPILEPSIAS 2010 Período Neonatal Infancia Niñez Adolescente-Adulto Relaciónmenosespecífica con la edad
  • 29. CLASIFICACIÓN DE SÍNDROMES ELECTROCLÍNICOS Y OTRAS EPILEPSIAS 2010 Constelaciones Mesial temporal lobe epilepsy with hippocampal sclerosis Epilepsias con causaestructural o metabólica SíndromesNeurocutáneos Epilepsias de causadesconocida Condiciones con crisis epilépticas no diagnosticadascomounaepilepsia per se Crisis Febriles
  • 31. G R A C I A S