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CEMENTUM
NIDHI PANDEY
PG 1ST YR
CONTENT
• Introduction
• History
• Definition
• Development
• Physical characteristics
• Biochemical composition
• Incremental lines
• Classification of cementum
• Junctions
– CDJ
– CEJ
• Functions
• Resorption & repair
• Age changes
• Abnormalities of cementum
• Applied aspects
• Conclusion
• References
INTRODUCTION
• Cementum is a mineralized
dental tissue covering the
anatomic root of teeth.
• It begins at the cervical portion
of the tooth at CEJ and
continues to the apex.
• Cementum furnishes a medium
for the attachment of collagen
fibers that bind the tooth to
surrounding structures.
HISTORY
• This tissue was not discovered and characterized on
human teeth until a full century later than enamel
and dentin.
• First detailed descriptions of human cementum was
in the 1830s by Jan Purkinje and Anders Retzius, who
identified for the first time acellular and cellular types
of cementum, and the resident cementocytes
embedded in the latter.
The functional importance of cementum was not
appreciated until detailed anatomical studies of the
periodontium were performed by G.V. Black and
others in the late nineteenth and early twentieth
centuries.
DEFINITION
• It is a specialized connective tissue that shares some
physical, chemical and structural characteristics with
compact bone.
-Orban’s oral histology
• Cementum is the calcified, avascular mesenchymal
tissue that forms the outer covering of the anatomic
root.
-Carranza 13th edition
• Cementum is an avascular mineralized
mesenchymal tissue covering the entire root
surface.
- Periobasics
DEVELOPMENT
PHYSICAL CHARACTERISTICS
• Hardness- less than cementum.
• Color- -light yellow in color.
-lighter than dentin.
-distinguished from enamel by its lack of
luster and darker hue.
• Thickness- varies in different teeth and in same teeth
in different regions.
-thinnest at CEJ (20-50um)
-thickest towards apex (150-200um)
• It is thicker in distal surfaces than in mesial surfaces,
probably because of functional stimulation from mesial drift
over time.
• Between the ages of 11 and 70 years, the average thickness
of the cementum increases threefold, with the greatest
increase seen in the apical region. Average thicknesses of 95
µm at the age of 20 years and of 215 µm at the age of 60
years have been reported.
-Zander HA(1958)
• Permeability-
– In very young animals, acellular cementum and cellular
cementum are very permeable and permit the diffusion of
dyes from the pulp and the external root surface.
– In cellular cementum, the canaliculi in some areas are
contiguous with the dentinal tubuli. The permeability of
cementum diminishes with age.
– Blayney JR(1941)
CHEMICAL COMPOSITION
cementum
Organic
content
45-50%
Inorganic
content
50-55%
Inorganic content-
• Principal mineral components-
– Calcium
– Phosphate
• Crystallinity is less.
• Has the higher fluoride content of all the mineralized
tissues.
HYDROXYAPATITE
Organic content-
• Collagen fibers – type 1
type 3, 5, 6, 12
• 2 major Glycoproteins- BSP , Osteopontin
• Cementum Derived Attachment Proteins
• Proteoglyacans:- Chondroitin sulphate
Heparan sulphate
Hyluronatee
Keratan sulphate
Versican, biglycan
enhance the
proliferation
of gingival
fibroblasts and
periodontal
ligament cells
• Growth factors: TGF-beta ,
BMPs,
PDGF,
CEMENTUM DERIVED GROWTH
FACTORS
Classification of cementum
• Depending on the presence or absence of
cementocytes:
1. Acellular
2. Cellular
• Depending on the origin and nature of organic matrix:
1. Extrinsic fiber cementum
2. Intrinsic fiber cementum
• Depending upon the time of formation, presence or
absence of cells, and on the nature and origin of
organic matrix:
1. Primary acellular intrinsic fiber cementum
2. Primary acellular extrinsic fiber cementum
3. Secondary cellular intrinsic fiber cementum
4. Secondary cellular mixed fiber cementum
5. Acellular afibrillar cementum
INCREMENTAL LINES
• Lines of salter!
• Highly mineralized areas.
• These are closer in acellular
cementum but in cellular
cementum they are widely
displaced.
• Are of value in age estimation.
JUNCTIONS OF
CEMENTUM
Cementoenamel junction (CEJ)
Cementodentinal junction (CDJ)
• CDJ consist of a wide zone
containing large quantities of
collagen associated with
Glycosaminoglycans
• Increased water content
• Contributes to the stiffness
CDJ-
• Collagen fibrils of cementum
and dentine interwine at their
interface in a very complex
fashion;
It is not possible to precisely
determine that which fibers
are of dentinal or cemental
origin.
FUNCTIONS
• ANCHORAGE: PRIMARY FUNCTION
• ADAPTATION: KEEPING ATTACHMENT APPARATUS
INTACT
• REPAIR: MAJOR REPARATIVE TISSUE
Resorption & repair
• Physiologic resorption-
• Areas of cementum resorption se with age.
• Cementum resorption appears microscopically as
baylike concavities in the root surface.
Primary teeth
Permanent teeth
• Systemic diseases asso. With cementum resorption-
– Paget’s disease
– Herediatary fibrous osteodystrophy
– Hypothyroidism
– Calcium deficiency
inflammation
Mechanical
trauma
TFO
Orthodontic
tooth
movement
Periapical
pathology
Pressure from
mal aligned
erupting
tooth
Repair -
• Repair of cementum occurs by deposition of new
cementum. Easily identified by reversal lines.
• The cementoblasts depositing new cementum are
derived from the surrounding connective tissue,
mostly from PDL.
• Under specific conditions, the epithelial rest of
Malassez may play an active role in repair.
-Hasegawa N (2003)
Age changes
• Thickness ses.
• The thickness of cementum on the distal root surface
is more than on the mesial root surface.
• The increase in width is greater apically and lingually.
Although cementum has limited capacity for
remodelling, an accumulation of resorption bays
explains the inding of increasing surface
irregularity.
ABNORMALITIES OF CEMENTUM
• HYPERCEMENTOSIS-
– An abnormal thickening of cementum.
– May be diffuse, circumscribed.
– May affect all teeth or a single tooth or even only parts of
a tooth.
• ANKYLOSIS:-
– Fusion of cementum with alveolar bone with obliterated
PDL.
– Seen with hypercementosis.
– After inflammation, occlusal trauma.
• CEMENTAL TEARS:-
– Tear along one incremental line or CDJ.
CLINICAL CONSIDERATION
• Resistance to resorption orthodontic tooth
movement.
• Repair
1. Anatomical repair
2. Functional repair
• Pathologically exposed cementum
• Cementum In Periodontal Involvement:
– Breakdown of dentogingival fibers.
– Loss of collagen fibers cross banding
– Dissolution of inorganic content.(soften)
Constant saliva Hypercalcified area
Plaque accumulation hypocalcified area
• Bacterial endotoxins found in cemental depths.
Structural changes interfere with healing
Applied Aspect
CEMENTUM IN PERIODONTAL
REGENERATION
CONCLUSION
• Cementum forms a functional unit which is designed to
maintain tooth support, integrity, and protection.
• Minor, non-pathological resorption defects on the root
surface are generally reversible and heal by reparative
cementum formation.
• Irreversible damage may occur when the cementum is
exposed to the environment of a pocket or oral cavity.
References
• Orban’s Oral histology and embryology – 12th edition
• Clinical periodontology by CARRANZA – 13th edition
• Biology of the periodontal connective tissues – P.
Mark Bartold
• Periobasics – Nitin Saroch
• Foster, B. L. (2017). On the discovery of cementum.
Journal of Periodontal Research, 52(4), 666–
685. doi:10.1111/jre.12444
Cementum

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Cementum

  • 1.
  • 3. CONTENT • Introduction • History • Definition • Development • Physical characteristics • Biochemical composition • Incremental lines • Classification of cementum • Junctions – CDJ – CEJ • Functions • Resorption & repair • Age changes • Abnormalities of cementum • Applied aspects • Conclusion • References
  • 4. INTRODUCTION • Cementum is a mineralized dental tissue covering the anatomic root of teeth. • It begins at the cervical portion of the tooth at CEJ and continues to the apex. • Cementum furnishes a medium for the attachment of collagen fibers that bind the tooth to surrounding structures.
  • 5. HISTORY • This tissue was not discovered and characterized on human teeth until a full century later than enamel and dentin. • First detailed descriptions of human cementum was in the 1830s by Jan Purkinje and Anders Retzius, who identified for the first time acellular and cellular types of cementum, and the resident cementocytes embedded in the latter.
  • 6. The functional importance of cementum was not appreciated until detailed anatomical studies of the periodontium were performed by G.V. Black and others in the late nineteenth and early twentieth centuries.
  • 7. DEFINITION • It is a specialized connective tissue that shares some physical, chemical and structural characteristics with compact bone. -Orban’s oral histology • Cementum is the calcified, avascular mesenchymal tissue that forms the outer covering of the anatomic root. -Carranza 13th edition
  • 8. • Cementum is an avascular mineralized mesenchymal tissue covering the entire root surface. - Periobasics
  • 10. PHYSICAL CHARACTERISTICS • Hardness- less than cementum. • Color- -light yellow in color. -lighter than dentin. -distinguished from enamel by its lack of luster and darker hue. • Thickness- varies in different teeth and in same teeth in different regions. -thinnest at CEJ (20-50um) -thickest towards apex (150-200um)
  • 11. • It is thicker in distal surfaces than in mesial surfaces, probably because of functional stimulation from mesial drift over time. • Between the ages of 11 and 70 years, the average thickness of the cementum increases threefold, with the greatest increase seen in the apical region. Average thicknesses of 95 µm at the age of 20 years and of 215 µm at the age of 60 years have been reported. -Zander HA(1958)
  • 12. • Permeability- – In very young animals, acellular cementum and cellular cementum are very permeable and permit the diffusion of dyes from the pulp and the external root surface. – In cellular cementum, the canaliculi in some areas are contiguous with the dentinal tubuli. The permeability of cementum diminishes with age. – Blayney JR(1941)
  • 14. Inorganic content- • Principal mineral components- – Calcium – Phosphate • Crystallinity is less. • Has the higher fluoride content of all the mineralized tissues. HYDROXYAPATITE
  • 15. Organic content- • Collagen fibers – type 1 type 3, 5, 6, 12 • 2 major Glycoproteins- BSP , Osteopontin • Cementum Derived Attachment Proteins • Proteoglyacans:- Chondroitin sulphate Heparan sulphate Hyluronatee Keratan sulphate Versican, biglycan enhance the proliferation of gingival fibroblasts and periodontal ligament cells
  • 16. • Growth factors: TGF-beta , BMPs, PDGF, CEMENTUM DERIVED GROWTH FACTORS
  • 17. Classification of cementum • Depending on the presence or absence of cementocytes: 1. Acellular 2. Cellular • Depending on the origin and nature of organic matrix: 1. Extrinsic fiber cementum 2. Intrinsic fiber cementum
  • 18. • Depending upon the time of formation, presence or absence of cells, and on the nature and origin of organic matrix: 1. Primary acellular intrinsic fiber cementum 2. Primary acellular extrinsic fiber cementum 3. Secondary cellular intrinsic fiber cementum 4. Secondary cellular mixed fiber cementum 5. Acellular afibrillar cementum
  • 19.
  • 20. INCREMENTAL LINES • Lines of salter! • Highly mineralized areas. • These are closer in acellular cementum but in cellular cementum they are widely displaced. • Are of value in age estimation.
  • 23. Cementodentinal junction (CDJ) • CDJ consist of a wide zone containing large quantities of collagen associated with Glycosaminoglycans • Increased water content • Contributes to the stiffness
  • 24. CDJ- • Collagen fibrils of cementum and dentine interwine at their interface in a very complex fashion; It is not possible to precisely determine that which fibers are of dentinal or cemental origin.
  • 25. FUNCTIONS • ANCHORAGE: PRIMARY FUNCTION • ADAPTATION: KEEPING ATTACHMENT APPARATUS INTACT • REPAIR: MAJOR REPARATIVE TISSUE
  • 26. Resorption & repair • Physiologic resorption- • Areas of cementum resorption se with age. • Cementum resorption appears microscopically as baylike concavities in the root surface. Primary teeth Permanent teeth
  • 27. • Systemic diseases asso. With cementum resorption- – Paget’s disease – Herediatary fibrous osteodystrophy – Hypothyroidism – Calcium deficiency inflammation Mechanical trauma TFO Orthodontic tooth movement Periapical pathology Pressure from mal aligned erupting tooth
  • 28. Repair - • Repair of cementum occurs by deposition of new cementum. Easily identified by reversal lines. • The cementoblasts depositing new cementum are derived from the surrounding connective tissue, mostly from PDL. • Under specific conditions, the epithelial rest of Malassez may play an active role in repair. -Hasegawa N (2003)
  • 29. Age changes • Thickness ses. • The thickness of cementum on the distal root surface is more than on the mesial root surface. • The increase in width is greater apically and lingually. Although cementum has limited capacity for remodelling, an accumulation of resorption bays explains the inding of increasing surface irregularity.
  • 30. ABNORMALITIES OF CEMENTUM • HYPERCEMENTOSIS- – An abnormal thickening of cementum. – May be diffuse, circumscribed. – May affect all teeth or a single tooth or even only parts of a tooth.
  • 31. • ANKYLOSIS:- – Fusion of cementum with alveolar bone with obliterated PDL. – Seen with hypercementosis. – After inflammation, occlusal trauma. • CEMENTAL TEARS:- – Tear along one incremental line or CDJ.
  • 32. CLINICAL CONSIDERATION • Resistance to resorption orthodontic tooth movement. • Repair 1. Anatomical repair 2. Functional repair • Pathologically exposed cementum
  • 33. • Cementum In Periodontal Involvement: – Breakdown of dentogingival fibers. – Loss of collagen fibers cross banding – Dissolution of inorganic content.(soften) Constant saliva Hypercalcified area Plaque accumulation hypocalcified area • Bacterial endotoxins found in cemental depths. Structural changes interfere with healing
  • 36. CONCLUSION • Cementum forms a functional unit which is designed to maintain tooth support, integrity, and protection. • Minor, non-pathological resorption defects on the root surface are generally reversible and heal by reparative cementum formation. • Irreversible damage may occur when the cementum is exposed to the environment of a pocket or oral cavity.
  • 37. References • Orban’s Oral histology and embryology – 12th edition • Clinical periodontology by CARRANZA – 13th edition • Biology of the periodontal connective tissues – P. Mark Bartold • Periobasics – Nitin Saroch • Foster, B. L. (2017). On the discovery of cementum. Journal of Periodontal Research, 52(4), 666– 685. doi:10.1111/jre.12444