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CARDIOSTIM 2010
A dva n ce p rogra m

                       18th World Congress
                       in Cardiac Electrophysiology
                       & C a r d i a c Te c h n i q u e s

                       June 13 > 16 I 2012
                       Nice • FrAncE




                                                                                      Painting by Françoise Persil­­­­lon




                                                     Advance program

                                                            www.cardiostim.com

                                                                        In collaboration with



                                                                 www.cardiostim.fr                                          1
Cardiostim 2012
                                                                                                         éditorial


European Heart Rhythm Association (EHRA) Program


                                A message
Wednesday June 13 / 00:00 AM           Wednesday June 13 / 00:00 AM
                                from the Chairman of Cardiostim
CARDIAC STEM CELLS AND GENE THERAPY    NEW IMAGING TECHNIQUES
Chair:                                                              Chair:
Cohen I. - Stony Brook, USA                                         Kalman J. - Melbourne, AUS
Fast V. - Birmingham, USA                                           Mazgalev T.N. - Cleveland, USA

•  aking Hearts Regenerate
   M                                                                   •  lectrocardiographic Imaging to Understand Arrhythmia
                                                                         E
Dear Colleagues, DearCHE
   Pedrazzini T. - Lausanne, Friends,                                    Mechanisms
•  ardiac Differentiation of Human Keratinocytes Derived from
   C                                                                     Rudy Y. - St. Louis, USA
Today is already tomorrow!
   Plucked Hair Follicles                                              •  imulations to Predict Sites of VT Ablation
                                                                         S
                                                                         Trayanova N. A. - come. Advances
In Binah O. - were announcing revolutions in the Electrophysiology world for the years to Baltimore, USA are now on the way, and
    2010, we Haifa, ISR
                                                                       •  RI for Risk Prediction of Arrhythmogenic Areas
                                                                         M
their first applications Stem Cells from Patients the 2012 edition of Cardiostim!
• nduced Pluripotent will be discussed during with Inherited
   I
                                                                         Halperin H. - saved by USA
Routine ablation procedures for VT/VF, especially during electrical storms in patientsBaltimore, their ICD, robotic and 3D mapping
   Arrhythmias
and navigation - Madison, USA                                          •  hat Are the Clinical Implications? management, transeptal,
                                                                         W new anticoagulants in AF
   January C. T. for EP and ablation techniques, contact force control,
pericardialthe robotic approaches to the left ventricle for CRT, cardiac simulation - Mannheim, DEU arrhythmia mechanisms and
•  hat Are or Clinical Implications?
   W
                                                                         Borggrefe M. for understanding
CRT, among many others, are some of the major topics that will be introduced Discussion
                                                                       •  eneral and debated!
                                                                         G
   Rosen M. R. - New York, USA
New recommendations on palpitation management and CRT implantation and follow-up will be presented. Formerly recognized
• General Discussion
indications will be revisited, such as vaso-vagal syncope, hypertrophic cardiomyopathy or Brugada syndrome. Lots of
debates will be organized as shows and you’ll be able to give your opinion through voting systems in many of the programs settled by
the most famous experts.
What is unique in Cardiostim is the atmosphere that brings more and more people to this friendly meeting where
attendees can freely express their opinion.
That is probably why, despite the international financial crisis, more than a thousand abstracts have been received from all over the
world, and especially from countries that were not present until now in our congress, demonstrating the interest of colleagues keen to
come to Nice to present their data and debate! Congratulations to all authors for their scientific contribution.
The EHRA Program Committee members, conducted by Andreas Goette (Leipzig – Germany), participated actively in the abstract
selection in addition to the Cardiostim members. Consequently, each abstract has been reviewed by at least 6 experts. The Selection
Committee rejected 43 % abstracts overall. This year, a smaller number of oral abstract sessions is proposed to enhance the quality
of the presented material. I must congratulate and thank everyone for these difficult tasks!
As can be seen along this Advance Program, the global result of the combination of EHRA sessions with the traditional programs
proposed by our American friends and the Cardiostim Team is a high standard program that one will remind as the most complete
and attractive ever!
Our task is to translate this knowledge into understandable and useful information for clinical practice. This is why
Cardiostim also proposes educational sessions based on case presentations in the general program as well as dedicated sessions.
With the same logics, specific sessions will be dedicated to technicians and nurses.
Next June, you will enjoy Cardiostim!
                                    The platform to consult and free download
                                           ECG and Epidemiology data                               Philippe Ritter - Chairman
                                        http://epdatabank.cardiostim.com



                                                                                          www.cardiostim.com                       3
springermedizin.de


  Up-to-date – Qualified –
  Online
  Clinical Research in Cardiology
  • Current and competent survey on the diagnosis and therapy of heart and vascular diseases
  • Impact Factor 2010: 3.466, rank 31/114 (Journal Citation Reports ® Thomson Reuters)
  • Official Journal of the German Cardiac Society



    www.crc.springer.de




                        Extensive
                          online
                         archive!




                                                                                               050357
Cardiostim 2012


Congress Highlights in 2012




THE EHRA PROGRAM
          An extensive program was designed by the Scientific Program Committee of EHRA, and will include a total
          number of 30 sessions.

HIGH-TECH ADVANCES
          Among many others, four sessions will focus on new technologies that will impact our practice in the future with
          the following topics: understanding of arrhythmia mechanisms and signal processing, computer simulation in
          electrophysiology and CRT.

HIGH STANDARD EDUCATION
          Educational material is proposed in all programs, based on Case presentations. In the EP and ablation section, a
          specific program is proposed by George Klein on Saturday June 16.
          In addition a Program is given in French on devices, and two sessions are dedicated to technicians and nurses.

EPDatabank by cardiostim
          New in Cardiostim! Educational material is available on http://epdatabank.cardiostim.com for your own
          purposes. Epidemiologic information, ECG tracings, EGMs, etc… can be downloaded for free!
          Don’t hesitate to submit yours!




                            The platform to consult and free download
                                   ECG and Epidemiology data
                                http://epdatabank.cardiostim.com




                                                                               www.cardiostim.com                       5
Advance program


Scientific Organizing Committee

CARDIOSTIM TEAM
Philippe Ritter (Bordeaux, FRA)
Pierre Bordachar, Stéphane Garrigue, Sylvain Reuter, Frédéric Sacher (Bordeaux, FRA), Mark O’Neill (London, GBR),
Vincent Probst (Nantes, FRA)

David Hayes (Rochester, USA)	                 J.Claude Daubert (Rennes, FRA)
Douglas Zipes (Indianapolis, USA)	            J.Jacques Blanc (Brest, FRA)


European Heart Rhythm Association (EHRA)
President: Angelo Auricchio (Lugano, CHE)
Europace 2013 Program Committee Chairman: Andreas Götte (Magdeburg, DEU)
Vice-Chairman: John M. Morgan (Southampton, GBR)


Preparation Committee for Scientific Programs
To date, will be implemented as we go along
Abi-Samra F. M. 	       USA      Butter C. 	         DEU       Dobrev D. 	             DEU    Gorenek B. 	          TUR
Adragao P. 	            PRT      Calkins H. 	        USA       Dodinot B. 	            FRA    Gras D. 	             FRA
Aliot E. 	              FRA      Callans D. 	        USA       Dolan B. 	              USA    Grunnet M. 	          DNK
Allessie M. 	           NLD      Camm A. J. 	        GBR       Dorian P. 	             CAN    Guiraudon G. M. 	     CAN
Alonso C. 	             FRA      Cannom D. S. 	      USA       Dubner S. 	             ARG    Guirgis M. 	          FRA
Amman P	                CHE      Cappato R. 	          ITA     Duffy H. 	              USA    Gulizia M. 	            ITA
Antzelevitch C. 	       USA      Capucci A. 	          ITA     Duytschaever M. 	       BEL    Hachiya H. 	          JPN
Arnar D	                 ICE     Carlson M. D. 	     USA       Efimov I. R. 	          USA    Haigney M. 	          USA
Asirvatham S. J. 	      USA      Cazeau S. 	         FRA       Ehrlich J. 	            DEU    Haines D. E. 	        USA
Atie J.	                BRA      Cha Y. M. 	         USA       Ellenbogen K. 	         USA    Haïssaguerre M. 	     FRA
Atienza F. 	            ESP      Chen S. A. 	        TWN       El-Sherif N. 	          USA    Halimi F	             FRA
Auricchio A. 	          CHE      Cheng J. 	          USA       Epstein L. 	            USA    Hammill S. C. 	       USA
Badhwar N. 	            USA      Chirife R. 	        ARG       Erdogan A. 	            DEU    Hasin Y. 	             ISR
Behrenbeck T. 	         USA      Clemmensen P.M. 	   DNK       Ernst S. 	              DEU    Hastrup Svendse J	    DNK
Belott P. H. 	          USA      Cohen I. 	          USA       Exner D. 	              CAN    Hatala R. 	           CZE
Benditt D. G. 	         USA      Cooke D. 	          USA       Ezekowitz M. D. 	       USA    Hayes D. 	            USA
Berenfeld O. 	          USA      Coronel R. 	        NLD       Fast V. 	               USA    Healey J. S. 	        USA
Biffi M. 	                ITA    Corrado D. 	          ITA     Fedorov V. 	            USA    Heidbüchel H. 	       BEL
Binner L. 	             DEU      Cowie M. 	          GBR       Fermont L. 	            FRA    Helland J. 	          USA
Blanc J. J. 	           FRA      Crijns H. J. 	      NLD       Fernandez Lozano I. 	   ESP    Hill M. 	             USA
Blomström-Lundqvist C. 	 WE
                       S         Curnis A. 	           ITA     Fishman G. I. 	         USA    Hindricks G. 	        DEU
Boersma L. 	            NLD      Danchin N. 	        FRA       Flammang D. 	           FRA    Hirao K. 	            JPN
Bongiorni M. G. 	         ITA    Darrel F. 	         GBR       Franz M. 	              USA    Ho I. 	               USA
Bordachar P. 	          FRA      Daubert J. C. 	     FRA       Friedman P. A. 	        USA    Hocini M. 	           FRA
Borggrefe M. 	          DEU      Davies W. 	         GBR       Furniss S. 	            GBR    Hoffmann E. 	         DEU
Boriani G. 	              ITA    Davy J. M. 	        FRA       Gaita F. 	               ITA   Hohnloser S. 	        DEU
Botto G. 	                ITA    De Chillou C. 	     FRA       Gammage M. 	            GBR    Hombach V. 	          DEU
Boveda S. 	             FRA      De Roy L. 	          BEL      Garrigue S. 	           FRA    Hornberger L. K. 	    USA
Boyden P. A. 	          USA      Deaton C	           GBR       Geelen P. 	             BEL    Husser D	             DEU
Brachmann J	            DEU      Defaye P. 	         FRA       Geller C. 	             DEU    Iacopino S. 	           ITA
Braunschweig F. 	      SWE       Deharo J. C. 	      FRA       Gerstenfeld E. 	        USA    Ideker R. E. 	        USA
Breithardt G. 	         DEU      Della Bella P. 	      ITA     Gilmour R. 	            USA    Ishikawa T. 	         JPN
Brignole M. 	             ITA    Delnoy P. P. 	      NLD       Giudici M. 	            USA    Israel C. W. 	        DEU
Brugada P. 	            BEL      Dickstein K. 	      NOR       Goette A. 	             DEU    Jackman W. M. 	       USA
Burri H. 	              CHE      Diener H. C. 	      DEU       Gold M. 	               USA    Jahangir A. 	         USA




6    www.cardiostim.com
Cardiostim 2012


Jaïs P. 	           FRA    McGann C. 	          USA     Rhode K. 	              GBR      Sternick E. 	           BRA
Jalife J. 	         USA    McKenna W. J. 	      GBR     Ricci R. 	                ITA    Stevenson W. G. 	       USA
Janse M. 	          NLD    McVenes R. 	         USA     Rich M. 	               USA      Sticherling C. 	        CHE
Jansens J. L. 	     BEL    Meine M. 	           NLD     Rinaldi A. 	              ITA    Stone P. H. 	           USA
Jauvert G.	         FRA    Meinertz T. 	        DEU     Rizzo G. 	                ITA    Stotts L. 	             USA
Jordaens L. 	       NLD    Mohr F. W. 	         DEU     Roberts P. 	            GBR      Suga C. 	                JPN
Jung W	             DEU    Molina L. 	          MEX     Roden D. M. 	           USA      Sulke N. 	              USA
Kaab S. 	           DEU    Mont L. 	            ESP     Rodriguez E. 	          ESP      Sutton R. 	             MCO
Kacet S. 	          FRA    Moorman A. 	         NLD     Roguin A. 	              ISR     Svendsen J. H. 	        DNK
Kalifa J. 	         USA    Morgan J. M. 	       GBR     Rohr S. 	               CHE      Szili-Török T. 	        NLD
Kalman J. M. 	      AUS    Morillo C. 	         CAN     Ronaszéki A. 	          HUN      Taborsky M. 	           CZE
Kautzner J. 	       CZE    Moss A. J. 	         USA     Rosen M. R. 	           USA      Tanel R. 	              USA
Kay N. 	            USA    Munger T. T. 	       USA     Rosenbaum D. S. 	       USA      Thambo J. B. 	          FRA
Keane D. 	          USA    Murgatroyd F. D. 	   GBR     Rowland E. 	            GBR      Thermistocles S. 	         ITA
Kennergren C. 	     SWE    Myerburg R. J. 	     USA     Rozkovec A. 	           DEU      Thibault B. 	           CAN
Kenny R. A. 	        IRL   Naccarelli G. V. 	   USA     Rudy Y. 	               USA      Thiene G. 	                ITA
Kirchhof P. 	       DEU    Nademanee K. 	       USA     Ruffy R. 	              USA      Thijs V. 	               BEL
Kleber A. 	         CHE    Nakagawa H. 	        USA     Ruiz-Granell R. 	       ESP      Tomaselli G. F. 	       USA
Klein G. J. 	       CAN    Nakazato Y. 	        JPN     Ruskin J. N. 	          USA      Tondo C. 	                 ITA
Klein H. 	          DEU    Nanthakumar K. 	     CAN     Sacher F. 	             FRA      Trayanova N. 	          USA
Klingenheben T. 	   DEU    Narayan S. M. 	      USA     Sadoul N. 	             FRA      Treede H. 	             DEU
Klug D. 	           FRA    Natale A. 	          USA     Saffitz J. E. 	         USA      Tristani-Firouzi M. 	   USA
Knecht S. 	         BEL    Nattel S. 	          CAN     Saghy L	                HUN      Tse H. F. 	             CHN
Knight B. 	         USA    Nerbonne J. 	        USA     Saksena S. 	            USA      Tseng G. N. 	           USA
Kottkamp H. 	       DEU    Neumann T. 	         DEU     Salama G. 	             USA      Tubaro M. 	                ITA
Krieger D. 	        DNK    Neuzil P. 	          CZE     Sanders P. 	            FRA      Turitto G. 	            USA
Krueger M. 	        DEU    Nielsen J. C. 	      DNK     Sanguinetti M. 	        USA      Valiunas V. 	           USA
Kuck K. H. 	        DEU    Nogami A. 	          JPN     Santini M. 	              ITA    van Gelder I. C. 	      NLD
Kusumoto F. 	       USA    Norihisa T. 	        JPN     Santomauro M. 	           ITA    Van Gelder B. 	         NLD
La Rovere M. T. 	    ITA   Olgin J. 	           USA     Savelieva I.	           GBR      Van Wagoner D. R. 	     USA
Lakatta E. 	        USA    Olshansky B. 	       USA     Saxon L. 	              USA      Vardas P. E. 	          GRC
Lau C. P. 	         CHN    O’Neill M. 	         GBR     Schaerf R. 	            USA      Varma N. 	              USA
Lazarus A. 	        FRA    Opthof T. 	          NLD     Schalij M. 	            NLD      Verrier R. L. 	         CAN
Lazzara R. 	        USA    Oseroff O. 	         ARG     Scheinman M.	           USA      Vesin J. M. 	           CHE
Le Heuzey J. Y. 	   FRA    Oto A. 	             TUR     Schilling R. 	          DEU      Viskin S. 	               ISR
Leclercq C. 	       FRA    Ovsyshcher E. 	       ISR    Schleich J. M. 	        FRA      Vlietstra R. 	          USA
Leclercq J-F	       FRA    Oyarzun R	           CHL     Schmidt B. 	            DEU      Vogt J. 	               DEU
Lee H. C. 	         USA    Packer D. L. 	       USA     Schmidt G. 	            DEU      Vohra J. K. 	           AUS
Leenhardt A. 	      FRA    Padeletti L. 	         ITA   Schotten U. 	           NLD      Vos M. 	                NLD
Lévy S. 	           FRA    Page R. L. 	         USA     Schuger C. 	            USA      Vrints C. 	              BEL
Lewalter T. 	       DEU    Panfilov A. V. 	     NLD     Schumacher B. 	         DEU      Waldo A. L. 	           USA
Lickfett L. 	       DEU    Pappone C. 	           ITA   Schwartz P. J. 	          ITA    Wallentin L. 	          DEU
Linde C. M. 	       SWE    Parkhomenko A. 	     UKR     Schweikert R. 	         USA      Weiss J. 	              USA
Linker N. J. 	      GBR    Parry S. W. 	        GBR     Schwitter J. 	          CHE      Wellens H. J. 	         NLD
Lip GYH	            GBR    Pedretti R. 	          ITA   Semisarian C. 	         AUS      Wieling W. 	            NLD
Locati E. 	          ITA   Pelleg A. 	          USA     Sermasant M.	           FRA      Wilber D. J. 	          USA
Loh P. 	            NDL    Piccini J. 	         USA     Sethi K. 	               IND     Wilde A. M. 	           NLD
London B. 	         USA    Piorkowski C. 	      DEU     Shah D. 	               CHE      Wilkoff B. L. 	         USA
Love C. J. 	        USA    Poelzing S. 	        DEU     Shaw R. 	               USA      Willems S. 	            DEU
Lubinski A. 	       POL    Pokushalov E	        RUS     Shen W. 	               USA      Wolpert C. 	            DEU
Mabo P. 	           FRA    Poole J. E. 	        USA     Shivkumar K. 	          USA      Xhaet O. 	              FRA
Maier L. 	          DEU    Pratt C. M. 	        USA     Shoda M. 	              JPN      Yamada K. 	             USA
Malik M. 	          GBR    Prinzen F. W. 	      NLD     Simantirakis E. N. 	    GRC      Yamane T. 	              JPN
Manolis A. S. 	     GRC    Priori S. G. 	         ITA   Siu D. 	                CHN      Yang Y. 	               USA
Mansour M. 	        USA    Pruvot E. 	          CHE     Sloman G. 	             AUS      Yu C. M. 	              CHN
Mantovan R. 	        ITA   Prystowsky E. N. 	   USA     Smith N. 	              GBR      Zannad F. 	             FRA
Marcus F. 	         USA    Puererfellner H. 	   AUT     Sogaard P. 	            DNK      Zareba W. 	             USA
Markijarvi M.	       FIN   Quinn T. 	           GBR     Sommer T. 	             DEU      Zaza A. 	                  ITA
Maron B. 	          USA    Rasmussen L. H. 	    DNK     Sperzel J. 	            DEU      Zeppenfeld K. 	         NLD
Marrouche N. F. 	   USA    Raviele A. 	           ITA   Squarcia U. 	             ITA    Zieman S. 	             USA
Martinek M. 	       AUT    Rea R. 	             USA     Steinbeck G. 	          DEU      Zipes D.P.	             USA
Mazgalev T. N. 	    USA    Reddy V. Y. 	        USA     Steinberg J. 	          USA      Zupan I. 	              SVN
McCarty J. 	        USA    Revishvilli A. 	     RUS     Steinhaus D. 	          USA
McElderry T. 	      USA    Reynolds D. W. 	     USA     Stern S. 	               ISR




                                                                               www.cardiostim.com                         7
Advance program


In collaboration with

• European Heart Rhythm Association (EHRA)
• Société Française de Cardiologie

• European Society of Cardiology

• Heart Rhythm Society (HRS)

• World Society of Arrhythmias WSA/ICPES

• International Society for Holter and Noninvasive Electrocardiology (ISHNE)

• Groupe Français d’Electrophysiologie et de Stimulation Cardiaque de la Société Française de Cardiologie

• Sociedad Asociación Civil Argentina de Estimulación Cardiaca (SADEC)

• Asian-Pacific Society of Cardiology

• Brazilian Society of Cardiology

• Latin-American Society of Pacing and Electrophysiology (SOLAECE)

• Artificial Cardiac Electrostimulation Department of the Brazilian Cardiac Surgery Group (DECA)

• Associazione Italiana di Aritmologia e Cardiostimolazione (AIAC)

• Mediterranean Society of Pacing and Electrophysiology (MESPE)

•  he RETAC Group (Reunion of European countries for the Treatment of Arrhythmias in Cardiology/Réseau Européen
  T
  pour le Traitement des Arythmies Cardiaques)


CME ACCREDITATION
EHRA SESSIONS at CARDIOSTIM 2012 are currently under review for accreditation by the European Board
for Accreditation in Cardiology (EBAC) for external CME credits.
The accreditation results will be announced online and in the final program.




                                Subscribe to Cardiostim newsletter
                      ✓         on www.cardiostim.com




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Cardiostim 2012


Contents

European Heart Rhythm Association (EHRA) Program.............................................................................................. P. 10

Basic Electrophysiology.............................................................................................................................................. P. 19

Complex Electrophysiology and Ablation Techniques.............................................................................................. P. 23
• Novel Approaches to Apply Mechanistic Insights to Complex Human Arrhythmias

Treatments for Atrial Fibrillation................................................................................................................................. P. 29
• Advances and Controversies in Atrial Fibrillation (ACAF)

Noninvasive Electrocardiology.................................................................................................................................... P. 30
• Educational Symposium of International Society for Holter and Noninvasive Electrocardiology (ISHNE)

Main Trials in the Management of Atrial Fibrillation.................................................................................................. P. 34

Acute Cardiac Care: Management of SCD.................................................................................................................. P. 35

Pacing, ICDs and CRT.................................................................................................................................................. P. 36

Leads............................................................................................................................................................................ P. 43

Associate Symposia.................................................................................................................................................... P. 45
• Cardiostim / HRS Joint Session
• Cardiopace
• Vaso Vagal Syncope
• Geriatric Cardiology
• Asia Pacific Cardiostim Symposium
• Palpitations
• Fetal Cardiology Symposium
• Pediatric Cardiac Electrophysiology
• Cardiostim-JHRS Joint Session
• Syncope
• ICE Program
• Italian Cardiostim Symposium
• EPIC Alliance

Industry Symposia....................................................................................................................................................... P. 53

Symposium STIMUPRAT.............................................................................................................................................. P. 59



                     The publisher and the Cardiostim organization disclaim any liability for errors or omissions that may come to light,
                                            despite the care taken in the production of this Advance Program.




                                                                                                                               www.cardiostim.com                                         9
Advance program


European Heart Rhythm Association (EHRA) Program
Organized by
the Scientific Committee of EHRA,
Coordination, Program Committee Andreas Götte - Magdeburg, DEU

Wednesday June 13 / 9:00 - 10:30                                   Wednesday June 13 / 9:00 - 10:30
CRT IN THE 21ST CENTURY. WHAT DO WE                                NEW INSIGHTS IN BASICS OF ARRHYTHMIAS
HAVE NOW? STATUS QUO AND QUO VADIS?                                Chair:
Chair:                                                             Crijns H. J. - Maastricht, NLD
Boriani G. - Bologna, ITA                                          Savelieva I. - London, GBR
Kuck K. H. - Hamburg, DEU
                                                                   •  alcium Handling and Arrhythmias: A Link to Be Targeted
                                                                     C
•  RT in Ischemic Heart Failure Patients: From Cell Function to
  C                                                                  Zaza A. - Milano, ITA
  Clinical Outcome                                                 •  Nodes» in the Arrhythmia Pathogenetic Network
                                                                     «
  Auricchio A. - Lugano, CHE                                         Schotten U. - Maastricht, NLD
•  RT in Patients with Atrial Fibrillation
  C                                                                •  itochondrial Dysfunction and Arrhythmias
                                                                     M
  Vardas P. E. - Heraklion, GRC                                      O’Rourke B. - Baltimore, USA
•  wo Years with New Guidelines. Do We Have Unresolved
  T                                                                •  linical Evidence and Possible Therapy of These Arrhythmias
                                                                     C
  Questions?                                                         Van Gelder I. C. - Groningen, NLD
  Dickstein K. - Stavanger, NOR
•  RT in Narrow QRS
  C
  Ponikowski P. - Wroclaw, POL


Wednesday June 13 / 9:00 - 10:30                                   Wednesday June 13 / 9:00 - 10:30
PACEMAKER THERAPY IN YEAR 2012                                     ION CHANNELOPATHIES
Chair:                                                             Chair:
Simantirakis E. N. - Heraklion, GRC                                Jalife J. - Ann Arbor, USA
Oyarzun R. - Santiago, CHL                                         Kaab S. - Munchen, DEU

•  ow Important Is Minimization of RV Pacing?
  H                                                                •  ong QT Syndrome - Types and Therapies
                                                                     L
  Israel C. W. - Bielefeld, DEU                                      Priori S. G. - Pavia, ITA
•  R Safe Pacemakers
  M                                                                •  rugada Syndrome - Place of Ion Channel Antiarrhythmic
                                                                     B
  Davy J. M. - Montpellier, FRA                                      Drugs
                                                                     Wolpert C. - Mannheim, DEU
•  here in the RV Should Ventricular Pacing Be Applied?
  W
  Butter C. - Bernau, DEU                                          •  Wave Syndromes
                                                                     J
                                                                     Antzelevitch C. - Utica, USA
•  hould AAI Pacing Be Considered Obsolete?
  S
  Nielsen J. C. - Aarhus, DNK                                      • diopathic Ventricular Fibrillation - Does It Exist?
                                                                     I
                                                                     Wilde A. M. - Amsterdam Zuidoost, NLD




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Cardiostim 2012


European Heart Rhythm Association (EHRA) Program



Wednesday June 13 / 11:00 - 12:30                                 Wednesday June 13 / 11:00 - 12:30
CRT: READING THE GUIDELINES                                       WHAT A DEVICE SPECIALIST NEEDS TO KNOW
Chair:                                                            ABOUT HEART FAILURE
Auricchio A. - Lugano, CHE                                        Chair:
Kirchhof P. - Birmingham, GBR                                     Daubert J. C. - Rennes, FRA
                                                                  Ponikowski P. - Wroclaw, POL
•  RT in Mild Heart Failure
  C
  Linde C. M. - Stockholm, SWE                                    •  acing in Heart Failure: What Happens on the Cellular Level?
                                                                    P
•  RT in Atrial Fibrillation
  C                                                                 Vanderheyden M. - Aalst, BEL
  Sutton R. - Monaco, MCO                                         •  ptimal Medical Treatment in Heart Failure
                                                                    O
•  RT in Patients with Conventional Pacemaker Indications
  C                                                                 Cowie M. - London, GBR
  Burri H. - Geneva, CHE                                          •  he Device Patient with End Stage Heart Failure
                                                                    T
•  RT in Clinical Practice: The European CRT Survey
  C                                                                 Fruhwald F. - Graz, AUT
  Dickstein K. - Stavanger , NOR                                  •  ole of Implantable Sensors in Heart Failure Management
                                                                    R
                                                                    Braunschweig F. - Stockholm, SWE

Wednesday June 13 / 11:00 - 12:30
PURKINJE FIBERS AND VENTRICULAR
ARRHYTHMIAS
Chair:
Kuck K. H. - Hamburg, DEU
Leclercq J. F. - Levallois, FRA

•  rrhythmia of Purkinje Fibers: Specificity of Cellular
  A
  Mechanisms
  Ehrlich J. - Frankfurt, DEU
•  ffect of Antiarrhythmic Drugs on the Purkinje Network:
  E
  Electrophysiological and Pharmacological Aspects
  Vos M. - Utrecht, NLD
•  blation of Polymorphic VT in Patients with Structural Heart
  A
  Disease
  TBD
• diopathic VF Originating from the Purkinje Network: Ablation
  I
  Targets and Long-Term Follow-Up
  Knecht S. - Brussels, BEL




                                                                                      www.cardiostim.com                        11
Advance program


European Heart Rhythm Association (EHRA) Program



Wednesday June 13 / 14:00 - 15:30                                   Wednesday June 13 / 16:00 - 17:30
NEW EHRA DOCUMENTS                                                  ICD THERAPY IN YEAR 2012
Chair:                                                              Chair:
Raviele A. - Venice, ITA                                            Garrigue S. - Bordeaux, FRA
                                                                    Svendsen J. H. - Copenhagen, DNK
•  alpitations
  P
  Raviele A. - Venice, ITA                                          •  efibrillation Testing during Implant: To Do or Not to Do?
                                                                      D
•  leeding Risk
  B                                                                   Baensch D. - Rostock, DEU
  Lip G. Y. - Birmingham, GBR                                       •  ow to Reduce Inappropriate Shock Therapy
                                                                      H
• ICD for Life’ Initiative-Fighting against Sudden Cardiac Death
  ‘                                                                   Wolpert C. - Mannheim, DEU
  in Emerging Economies.                                            •  eliability of Implantable Devices and Leads - Are They Good
                                                                      R
  Merkely B. - Budapest, HUN                                          Enough?
•  enetic Testing
  G                                                                   Steinhaus D. M. - Mounds View, USA
  Priori S. G. - Pavia, ITA                                         •  ow Should We Program Tachy Parameters in ICDs.
                                                                      H
                                                                      Zupan I. - Ljubljana, SVN


Wednesday June 13 / 14:00 - 15:30                                   Wednesday June 13 / 16:00 - 17:30
SUDDEN CARDIAC DEATH IN THE YOUNG                                   STATE-OF-THE ART ON VENTRICULAR
Chair:                                                              TACHYCARDIA ABLATION
Heidbüchel H. - Leuven, BEL                                         Chair:
Morgan J. M. - Southampton, GBR                                     De Chillou C. - Nancy, FRA
                                                                    Wellens H. J. - Maastrisht, NLD
•  utopsy Rate and Cause of Death in the Young: A National
  A
  Study from Denmark                                                •  ndocardial Catheter Ablation of Monomorphic VT: From
                                                                      E
  Winkel B. G. - Copenhagen, DNK                                      Bench to EP Lab
•  rugada Syndrome: Not as Dangerous as First Assumed?
  B                                                                   Atie J. - Rio do Janeiro, BRA
  Borggrefe M. - Mannheim, DEU                                      •  picardial Approach: A First Line Therapy?
                                                                      E
•  ow Should We Make a Work-Up in Young Cardiac Arrest
  H                                                                   Della Bella P. - Milano, ITA
  Survivors?                                                        •  ew Mapping and Ablation Strategies for Catheter Ablation of
                                                                      N
  Braunschweig F. - Stockholm, SWE                                    VT in Patients with Dilated Cardiomyopathies
•  oronary Abnormalities and Sudden Cardiac Death
  C                                                                   Piorkowski C. - Leipzig, DEU
  Ho S. Y. - London, GBR                                            •  ombined Ablation Endo-Epicardial Approach for VT Ablation
                                                                      C
                                                                      Kottkamp H. - Zurich, CHE




12   www.cardiostim.com
Cardiostim 2012


European Heart Rhythm Association (EHRA) Program



Thursday June 14 / 09:00 - 10:30                                   Thursday June 14 / 11:00 - 12:30
PREVENTING SUDDEN CARDIAC DEATH WITH                               HIGHLIGHTS FROM EUROPACE 2011: DEVICE
RF ABLATION                                                        THERAPY, INTERVENTIONAL EP AND MEDICAL
Chair:                                                             THERAPY
Haïssaguerre M. - Pessac, FRA                                      Chair:
Mont L. - Barcelona, ESP                                           Auricchio A. - Lugano, CHE
                                                                   Hindricks G. - Leipzig, DEU
•  apping and Ablation of Idiopathic Ventricular Fibrillation
  M
  Sacher F. - Bordeaux, FRA                                        • nterventional EP
                                                                     I
•  revention of VF Episodes in Brugada Syndrome by Catheter
  P                                                                  Merino J. L. - Madrid, ESP
  Ablation                                                         •  harmacotherapy
                                                                     P
  Merino J. L. - Madrid, ESP                                         Camm A. J. - London, GBR
•  ombined Endocardial and Epicardial Ablation in Patients with
  C                                                                •  acing
                                                                     P
  ARVD                                                               Vardas P. E. - Heraklion, GRC
  Wissner E. - Hamburg, DEU
                                                                   •  efibrillation and CRT-D
                                                                     D
•  atheter Ablation of Ventricular Electrical Storms
  C                                                                  Wolpert C. - Mannheim, DEU
  Atie J. - Rio do Janeiro, BRA



Thursday June 14 / 09:00 - 10:30
STROKE PREVENTION IN ATRIAL FIBRILLATION:
STATE-OF-THE ART AND NEW CONCEPTS
Chair:
Camm A. J. - London, GBR
Rasmussen L. H. - Aalborg, DNK

•  asic Science Insights into the Prothrombotic State in Atrial
  B
  Fibrillation
  De Caterina R. - Chieti, ITA
•  linical Trial Update - What Do the RELY, ROCKET,
  C
  ARISTOTLE and AVERROES Trials Tell Us?
  Lip G. Y. - Birmingham, GBR
•  oes Aspirin Still Have a Role in Atrial Fibrillation?
  D
  Grond M. - Berlin, DEU
•  hat Should the New Guideline Revisions on Stroke
  W
  Prevention Look Like?
  Kirchhof P. - Birmingham, GBR




                                                                                       www.cardiostim.com     13
Advance program


European Heart Rhythm Association (EHRA) Program



Thursday June 14 / 14:00 - 15:30                        Thursday June 14 / 16:00 - 17:30
CRT IMPLANTATION AND FOLLOW-UP:                         THE CHALLENGES OF THE ASYMPTOMATIC
EHRA-HRS CONSENSUS STATEMENT                            PATIENT IN HEREDITARY SYNDROMES
Chair:                                                  Chair:
Daubert J.C. - Rennes, FRA                              Priori S. G. - Pavia, ITA
Saxon L. - Los Angeles, USA                             Wolpert C. - Mannheim, DEU

•  re-Implant Evaluation
  P                                                     •  symptomatic Patient with Long QT Syndrome
                                                          A
  Brignole M. - Lavagna, ITA                              Schulze-Bahr E. - Munster, DEU
• mplantation
  I                                                     •  symptomatic Patient with Brugada Syndrome
                                                          A
  Singh J. - Boston, USA                                  Brugada Terradellas P. - Brussels, BEL
•  re-Discharge Evaluation
  P
                                                        •  symptomatic Patient with Early Repolarization Syndrome
                                                          A
  Leclercq C. - Rennes, FRA
                                                          Haïssaguerre M. - Bordeaux, FRA
•  evice and Heart Failure Follow-Up
  D
  Israel C.W. - Frankfurt, DEU                          •  symptomatic Patient with Catecholaminergic Polymorphic VT
                                                          A
•  esponse to CRT
  R                                                       Wanguemert Perez F. - Las Palmas, ESP
  Gold M. - Charleston, USA
•  pecific Issues
  S
  Saxon L. - Los Angeles, USA


Thursday June 14 / 16:00 - 17:30                        Thursday June 14 / 16:00 - 17:30
CONTEMPORARY CONSIDERATIONS BASED ON                    TRANSLATIONAL APPROACHES IN ATRIAL
TECHNOLOGICAL DEVELOPMENTS IN CARDIAC                   FIBRILLATION
PACING                                                  Chair:
Chair:                                                  Zaza A. - Milano, ITA
Botto G. - Como, ITA                                    Goette A. - Magdeburg, DEU
Sutton R. - Monte Carlo, MCO
                                                        •  enes and Mutations in Patients with Lone Atrial Fibrillation:
                                                          G
•  hould All Permanent Pacemakers Be MRI Compatible?
  S                                                       Do They Matter?
  Santini M. - Roma, ITA                                  Olesen M. - Copenhagen, DNK
• s Telemonitoring a New Necessity?
  I                                                     • onic Remodelling: From Bench to Bedside
                                                          I
  Burri H. - Geneva, CHE                                  Van Gelder I. C. - Groningen, NLD
•  eadless Pacing: A Step Forward?
  L                                                     •  tructural Remodeling: Which Impact for Catheter Ablation?
                                                          S
  Roberts P. - Southampton, GBR                           Schotten U. - Maastricht, NLD
•  iological Pacemakers: A Futuristic Approach?
  B                                                     •  trial and Ventricular Oxidatives Stress during Atrial
                                                          A
  Israel C. W. - Bielefeld, DEU                           Fibrillation
                                                          Lendeckel U. - Greifswald, DEU




14   www.cardiostim.com
Cardiostim 2012


European Heart Rhythm Association (EHRA) Program



Friday June 15 / 09:00 - 10:30                                   Friday June 15 / 11:00 - 12:30
IMPROVING OUTCOMES IN THE CATHETER                               COMPLICATIONS RELATED TO ATRIAL
ABLATION OF ATRIAL FIBRILLATION                                  FIBRILLATION CATHETER ABLATION
Chair:                                                           Chair:
Kautzner J. - Praha, CZE                                         Gaita F. - Asti, ITA
Kuck K. H. - Hamburg, DEU                                        Hatala R. - Bratislava, SVK

•  enervation of the Heart. The Role of gP Ablation in Atrial
  D                                                              •  revalence and Predictors of Complications of Radiofrequency
                                                                   P
  Fibrillation Treatment                                           Catheter Ablation for Atrial Fibrillation
  Pokushalov E. - Novosibirsk, RUS                                 Kautzner J. - Praha, CZE
•  arly Ablation of Atrial Fibrillation. Would We Have Better
  E                                                              •  atheter Ablation on Uninterrupted Warfarin: Is It Safe?
                                                                   C
  Long-Term Results in the Future?                                 Schilling R. - London, GBR
  Kirchhof P. - Birmingham, GBR                                  • ncidence of Silent Cerebral Thromboembolic Lesions after
                                                                   I
•  atheter Ablation of the Long-Standing Persistent Atrial
  C                                                                Atrial Fibrillation Ablation: Predictive Factors?
  Fibrillation. Where We Are Now?                                  Scaglione M. - Asti, ITA
  Willems S. - Hamburg, DEU                                      •  ong-Term Rates of Death, Stroke, and Dementia Following
                                                                   L
•  urrent Standard of Care in Atrial Fibrillation Ablation
  C                                                                Atrial Fibrillation Ablation
  Jaïs P. - Bordeaux, FRA                                          Day J. - Salt Lake City, USA

Friday June 15 / 09:00 - 10:30                                   Friday June 15 / 11:00 - 12:30
THE COMPLEX PACEMAKER IMPLANTATION                               CONTINUOUS MONITORING IN ATRIAL
Chair:                                                           FIBRILLATION MANAGEMENT. NEW SCIENCE
Davy J. M. - Montpellier, FRA                                    OR NEW TRUTH?
Ponikowski P. - Wroclaw, POL                                     Chair:
                                                                 Lewalter T. - Bonn, DEU
•  evice Implant in Case of Subclavian Vein Occlusion
  D                                                              Zupan I. - Ljubljana, SVN
  Bracke F. - Eindhoven, NLD
• mplantation of a Pacing System in GUCH Patients
  I                                                              •  ymptomatic/Asymptomatic Events after AF Ablation
                                                                   S
  Morgan J. M. - Southampton, GBR                                  Hindricks G. - Leipzig, DEU
•  acing Considerations in Pediatric Patients
  P                                                              •  nticoagulation/Antiarrhythmic Management after AF Ablation
                                                                   A
  Cantu F. - Bergamo, ITA                                          Kirchhof P. - Birmingham, GBR
•  acemaker Therapy after TAVI Procedure
  P                                                              •  F Burden in Assessment of Long-Term Success after AF
                                                                   A
  Wissner E. - Hamburg, DEU                                        Ablation
                                                                   Puererfellner H. - Linz, AUT
                                                                 •  anagement of Early Post-Operative Period. Who Will Need
                                                                   M
                                                                   Early Reablation?
                                                                   Pokushalov E. - Novosibirsk, RUS




                                                                                     www.cardiostim.com                      15
Advance program


European Heart Rhythm Association (EHRA) Program



Friday June 15 / 14:00 - 15:30                                       Friday June 15 / 16:00 - 17:30
ADVANCES IN ROBOTIC AND 3D MAPPING                                   DIAGNOSTIC EVALUATION OF SYNCOPE IN
TECHNOLOGIES FOR ATRIAL FIBRILLATION                                 SPECIAL PATIENT GROUPS
ABLATION                                                             Chair:
Chair:                                                               Morgan J. M. - Southampton, GBR
Kautzner J. - Praha, CZE                                             Theodorakis G. - Athens, GRC
Santini M. - Roma, ITA
                                                                     •  atients with Bundle Branch Block
                                                                       P
•  emote Magnetic Catheter Navigation: Is It the «Gold Standard»?
  R                                                                    Moya A. - Barcelona, ESP
  Ernst S. - Hamburg, DEU                                            •  yncope in Athletes
                                                                       S
•  ethods, Efficacy, and Safety of Robotic Catheter Ablation for
  M                                                                    Flevari P. - Halandri, GRC
  Atrial Fibrillation                                                •  yncope in the Elderly: Particularities
                                                                       S
  Pisapia A. - Marseille, FRA                                          Kenny R. A. - Dublin, IRL
•  hree-Dimensional Rotational Angiography: A New Online
  T                                                                  •  yncope Unit: A New Necessity?
                                                                       S
  Imaging Tool                                                         Brignole M. - Lavagna, ITA
  Noelker G. - Bad Oeynhausen, DEU
•  atheter Ablation of Atrial Fibrillation Using a New Non-
  C
  Fluoroscopic Sensor-Guided 3D Navigation Tool
  Hindricks G. - Leipzig, DEU


Friday June 15 / 14:00 - 15:30                                       Friday June 15 / 16:00 - 17:30
MANAGEMENT OF PATIENTS WITH                                          ARRHYTHMIAS IN WOMEN: STATE OF THE
DEFIBRILLATOR SHOCKS: STATE-OF-THE ART                               EVIDENCE
Chair:                                                               Chair:
Boriani G. - Bologna, ITA                                            Borggrefe M. - Mannheim, DEU
Morgan J. M. - Southampton, GBR                                      Heidbüchel H. - Leuven, BEL

• ncidence, Predictors and Impact on Mortality
  I                                                                  •  anaging Arrhythmias in Pregnancy: What’s in the Guidelines?
                                                                       M
  van Rees H. - Den Haag, NLD                                          Blomstrom-Lundqvist C. - Uppsula, SWE
• CD Configuration and Programming to Optimise Shock
  I                                                                  •  ender Differences in Atrial Fibrillation
                                                                       G
  Treatment                                                            Mont L. - Barcelona, ESP
  Katz A. - Ashkelon, ISR                                            •  utcomes in Women Undergoing Electrophysiological
                                                                       O
•  esults of Catheter Ablation in Patients with Shocks
  R                                                                    Procedures
  Arenal Maiz A. - Madrid, ESP                                         Santangeli P. - Austin, USA
•  ow to Manage Patient Anxiety
  H                                                                  • mplantable Cardioverter Defibrillators in Women
                                                                       I
  Ladwig K. H. - München, DEU                                          Zupan I. - Ljubljana, SVN




16   www.cardiostim.com
Cardiostim 2012


European Heart Rhythm Association (EHRA) Program



Friday June 15 / 16:00 - 17:30                                   Saturday June 16 / 09:00 - 10:30
NEW ENERGIES AND TECHNOLOGIES TO TREAT                           CERTIFICATION: FIGHTING AGAINST INEQUALITY
ATRIAL FIBRILLATION                                              IN HEALTH CARE ACROSS BORDERS
Chair:                                                           Chair:
Davies W. - London, GBR                                          Auricchio A. - Lugano, CHE
Kuck K. H. - Hamburg, DEU                                        Nielsen J. C. - Aarhus, DNK

•  apping and Pulmonary Vein Isolation Using the PVAC
  M                                                              •  Powerful Tool for Improvement in Health Care
                                                                   A
  Duytschaever M. - Brugges, BEL                                   Zeppenfeld K. - Leiden, NLD
•  ryoballoon Pulmonary Vein Isolation Guided by Real-Time PV
  C                                                              •  odels to Be Listened: UK
                                                                   M
  Potential Recording                                              Linker N. J. - Middlesbrough, GBR
  Hoffmann E. - Munich, DEU                                      •  ertification of Allied Professionals
                                                                   C
•  ow-Level Vagosympathetic Nerve Stimulation: A New Target
  L                                                                Nolan P. - Galway, IRL
  for Atrial Fibrillation Suppression?                           •  ertification in Europe: Differences with and Lessons from USA
                                                                   C
  Jackman W. M. - Oklahoma City, USA                               Arribas Ynsaurriaga F. - Madrid, ESP
•  inimally Invasive Surgical Techniques: For Which Patients?
  M
  La Meir M. - Maastricht, NLD
                                                                 Saturday June 16 / 09:00 - 10:30
                                                                 DEBATES AND CONTROVERSIES IN THE
                                                                 ANTITHROMBOTIC MANAGEMENT OF ATRIAL
                                                                 FIBRILLATION
                                                                 Chair:
                                                                 Savelieva I. - London, GBR

                                                                 •  ow Risk Patients with Atrial Fibrillation Can Be Treated with
                                                                   L
                                                                   No Antithrombotic Therapy: FOR
                                                                   Fauchier L. - Tours, FRA
                                                                 •  ow Risk Patients with Atrial Fibrillation Can Be Treated with
                                                                   L
                                                                   No Antithrombotic Therapy: AGAINST
                                                                   Rasmussen L. H. - Aalborg, DNK
                                                                 •  ntiplatelet Therapy Should Be Added to Anticoagulant Therapy
                                                                   A
                                                                   in Patients with Atrial Fibrillation and Vascular Disease: FOR
                                                                   Rubboli A. - Bologna, ITA
                                                                 •  ntiplatelet Therapy Should Be Added to Anticoagulant Therapy
                                                                   A
                                                                   in Patients with Atrial Fibrillation and Vascular Disease: AGAINST
                                                                   Marin F. - Murcia, ESP




                                                                                       www.cardiostim.com                          17
Advance program


European Heart Rhythm Association (EHRA) Program


Saturday June 16 / 11:00 - 12:30                                           Saturday June 16 / 11:00 - 12:30
ANTIARRHYTHMIC DRUGS FOR ATRIAL                                            NURSE-LED INTERVENTIONS FOR PATIENTS
FIBRILLATION                                                               WITH ARRHYTHMIAS
Chair:                                                                     Chair:
Capucci A. - Ancona, ITA                                                   Linker N. J. - Middlesbrough, GBR
van Gelder I. C. - Groningen, NLD                                          Zeppenfeld K. - Leiden, NLD

•  asics of Ion Channel Antiarrhythmic Drugs for Prevention of
  B                                                                        •  OPE-ICD Trial: Comprehensive Rehabilitation for Patients
                                                                             C
  Atrial Fibrillation                                                        with Implantable Defibrillators
  Dobrev D. - Heidelberg, DEU                                                Kikkenborg Berg S. - Copenhagen, DNK
•  asics of Upstream Therapies for Prevention of Atrial Fibrillation
  B                                                                        •  educing Psychological Distress for Patients with Implantable
                                                                             R
  Goette A. - Magdeburg, DEU                                                 Defibrillators
• on Channel Antiarrhythmic Drugs for Prevention of Atrial Fibrillation
  I                                                                          Dunbar S. - Atlanta, USA
  Crijns H. J. - Maastricht, NLD                                           • mplementing a Nurse-Led Atrial Fibrillation Clinic
                                                                             I
•  pstream Therapies for Prevention of Atrial Fibrillation
  U                                                                          Hendriks J. M. L. - Maastricht, NLD
  Savelieva I. - London, GBR                                               •  alpitations: Effectiveness of A Nurse-Led Clinic
                                                                             P
                                                                             Smallwood A. - Wolverhampton, GBR


In parallel with the scientific sessions, EHRA will hold a General Assembly to update members and attendees on its activities, while
meetings of various committees and working groups will take place throughout the Congress.

 EHRA Membership 2012, DISCOVER YOUR BENEFITS ON OUR WEB SITE
 •  pecial registration fee for EHRA educational courses
   S
 •  ree registration for the EHRA Webinars (e-learning)
   F
 •  5% discount on EHRA Certification Examinations
   1
 • 10% off all cardiology publications from Oxford University Press (OUP).
 • Reduced fee for the EP Europace journal
 •  xclusive access to EHRA Training Fellowships and a selection of EHRA Educational Content Online
   E
 •  utomatic ESC membership and benefits: Free ESC Pocket Guidelines at the ESC Congress,
   A
   Discount prices on the ESC Educational Products, Special subscription prices on ESC Journals
   (including EHJ), Receive ESC congresses related information, Receive ESC Educational Programme
   information, A personal European Membership Card (currently for members of some National Cardiac
   Societies only)
 • Receiving the EHRA E-newsletter
 • Voting rights

                                              More at WWW.ESCARDIO.ORG/EHRA




18    www.cardiostim.com
Cardiostim 2012


Basic Electrophysiology
Chairman: D. Zipes - Indianapolis, USA

                                                    Scientific Committee

 Ackerman M. - Rochester, USA                                    Nattel S. - Montreal, CAN
 Anderson M.E. - Iowa City, USA                                  Priori S. G. - Pavia, ITA
 Antzelevitch C. - Utica, USA                                    Roden D.M. - Nashville, USA
 Borggrefe M. - Mannheim, DEU                                    Rosen M. R. - New York, USA
 Boyden P. - New York, USA                                       Rosenbaum D.S. - Cleveland, USA
 Chen P.S. - Indianapolis, USA                                   Rudy Y. - St Louis, USA
 Delmar M. - New York, USA                                       Saffitz J. - Boston, USA
 Ideker R. - Birmingham, USA                                     Schwartz P. J. - Pavia, ITA
 Jalife J. - Ann Arbor, USA                                      Tomaselli G. - Baltimore, USA
 Kleber A. - Bern, CHE                                           Trayanova N. A. - Baltimore, USA
 London B. - Pittsburgh, USA                                     Weiss J. - Los Angeles, USA
 Mazgalev T.N. - Cleveland, USA                                  Wilde A. M. - Amsterdam Zuidoost, NLD
 Moss A.J. - Rochester, USA


       TRANSLATIONAL DISCOVERIES IN CARDIAC ELECTROPHYSIOLOGY: From Cell to Bedside


Wednesday June 13 / 09:00 - 10:30                                Wednesday June 13 / 11:00 - 12:30
CARDIAC STEM CELLS AND GENE THERAPY                              NEW IMAGING TECHNIQUES
Chair:                                                           Chair:
Cohen I. - Stony Brook, USA                                      Kalman J. - Melbourne, AUS
Fast V. - Birmingham, USA                                        Mazgalev T.N. - Cleveland, USA

•  aking Hearts Regenerate
   M                                                             •  lectrocardiographic Imaging to Understand Arrhythmia
                                                                   E
   Pedrazzini T. - Lausanne, CHE                                   Mechanisms
•  ardiac Differentiation of Human Keratinocytes Derived from
   C                                                               Rudy Y. - St. Louis, USA
   Plucked Hair Follicles                                        •  imulations to Predict Sites of VT Ablation
                                                                   S
   Binah O. - Haifa, ISR                                           Trayanova N. A. - Baltimore, USA
                                                                 •  RI for Risk Prediction of Arrhythmogenic Areas
                                                                   M
• nduced Pluripotent Stem Cells from Patients with Inherited
   I
                                                                   Halperin H. - Baltimore, USA
   Arrhythmias
                                                                 •  hat Are the Clinical Implications?
                                                                   W
   January C. T. - Madison, USA
                                                                   Borggrefe M. - Mannheim, DEU
•  hat Are the Clinical Implications?
  W                                                              •  eneral Discussion
                                                                   G
   Rosen M. R. - New York, USA
• General Discussion




                                                                                     www.cardiostim.com                     19
Advance program


Basic Electrophysiology


Wednesday June 13 / 14:00 - 15:30                               Thursday June 14 / 09:00 - 10:30
MYOCYTE-FIBROBLAST INTERACTIONS IN                              CONTRIBUTION OF GENETICS TO
NORMAL AND DISEASED MYOCARDIUM                                  UNDERSTANDING MECHANISMS AND RISK
Chair:                                                          Chair:
Kleber A. - Bern, CHE                                           Sanders P. - Adelaide, AUS
Vos M. - Utrecht, NLD                                           Lazzara R. - Oklahoma City, USA

•  yocyte Fibroblast Interaction
   M                                                            •  xperimental Models to Explain Inherited Diseases
                                                                   E
   Kohl P. - London, GBR                                           Antzelevitch C. - Utica, USA
•  yofibroblasts as Arrhythmia Triggers
   M                                                            •  athology to Explain Phenotype
                                                                   P
   Rohr S. - Bern, CHE                                             Basso C. - Padova, ITA
•  lectromechanical Consequences of Adult Cardiomyocyte
   E                                                            •  ellular Electrophysiology to Explain Clinical Phenotypes
                                                                   C
   Myofibroblast Interactions                                      Napolitano C. - Pavia, ITA
   Jalife J. - Ann Arbor, USA
                                                                •  hat Are the Clinical Implications?
                                                                  W
•  hat Are the Clinical Implications?
  W                                                                Moss A. J. - Rochester, USA
   Duffy H. - Boston, USA
                                                                • General Discussion
• General Discussion


Wednesday June 13 / 16:00 - 17:30                               Thursday June 14 / 11:00 - 12:30
CARDIAC ION CHANNELS AND                                        DOES GENETIC TESTING FOR SUDDEN DEATH
MACROMOLECULAR COMPLEXES IN HEALTH                              HELP IN CLINICAL PRACTICE?
AND DISEASE                                                     Chair:
Chair:                                                          Tseng G. N. - Richmond, USA
Fishman G. - New York, USA                                      Priori S. G. - Pavia, ITA
Fedorov V. - Columbus, USA
                                                                • Syndrome
•  acromolecular Complexes and the Control of Cardiac Ion
   M                                                               Schwartz P. J. - Pavia, ITA
   Channel Expression and Distribution                          •  rugada Syndrome and CPVT
                                                                   B
   Abriel H. - Bern, CHE                                           Brugada P. - Aalst, BEL
• ntercalated Disc as a Macromolecular Complex Niche and Its
   I                                                            • Hypertrophic Cardiomyopathy
   Role in ARVC                                                    Maron B. - Minneapolis, USA
   Delmar M. - New York, USA                                    •  ut of Hospital Cardiac Arrest
                                                                   O
•  AGUK Proteins Are Important in Ion Channel Diseases
   M                                                               Chugh S. S. - Los Angeles, USA
   Hatem S. - Paris, FRA                                        •  hat Are the Clinical Implications?
                                                                  W
•  hat Are the Clinical Implications?
  W                                                                Viskin S. - Tel Aviv, ISR
   Coronel R. - Amsterdam, NLD
• General Discussion




20   www.cardiostim.com
Cardiostim 2012


Basic Electrophysiology


Thursday June 14 / 14:00 - 15:30                                Friday June 15 / 09:00 - 10:30
THE INTERCALATED DISC AND                                       ROLE OF CaMKII IN ARRHYTHMIAS
ARRHYTHMOGENIC CARDIOMYOPATHY                                   Chair:
Chair:                                                          Maier L. - Goettingen, DEU
Poelzing S. - Salt Lake City, USA                               Gilmour R. - Ithaca, USA
Ehrlich J. - Frankfurt, DEU
                                                                •  aMKII Regulation of Ion Channels
                                                                  C
•  ased on Science, What Is the Best Name for Arrhythmogenic
  B                                                               Pitt G. - Durham, USA
  Right Ventricular Cardiomyopathy?                             •  aMKII Regulation of RyR Receptors and Ca Cycling
                                                                  C
  McKenna W. - London, GBR                                        Wehrens X. H. - Houston, USA
•  ell-Cell Communication in ARVC
  C                                                             •  ole of CaMKII in Cardiac Arrhythmias
                                                                  R
  Greene K. - Chicago, USA                                        Mohler P. J. - Columbus, USA
•  rrhythmia Mechanisms and Therapy
  A                                                             •  aMKII as a Potential Antiarrhythmic Target
                                                                  C
  Calkins H. - Baltimore, USA                                     Maier L. - Goettingen, DEU
•  hat Is Needed for a Cure?
  W                                                             •  hat Are the Clinical Implications?
                                                                  W
  Thiene G. - Padova, ITA                                         Rosenbaum D. S. - Cleveland, USA
•  hat Are the Clinical Implications?
  W
  Marcus F. - Tucson, USA


Thursday June 14 / 16:00 - 17:30                                Friday June 15 / 11:00 - 12:30
UNDERSTANDING ATRIAL FIBRILLATION                               ROLE OF THE AUTONOMIC NERVOUS SYSTEM
Chair:                                                          IN ARRHYTHMOGENESIS
Hocini M. - Bordeaux, FRA                                       Chair:
Probst V. - Nantes, FRA                                         Yamada K. - St. Louis, USA
                                                                Franz M. - Washington, USA
•  otassium Channel Remodeling
   P
   Nattel S. - Montreal, CAN                                    •  ympathetic-Vagal Interactions in Conscious Dogs
                                                                   S
•  emodeling of Calcium Handling
   R                                                               Lin S- F. - Indianapolis, USA
   Dobrev D. - Heidelberg, DEU                                  •  agal Modulation of Atrial Arrhythmias
                                                                  V
• Structural Remodeling                                           Po S. - Oklahoma City, USA
   Allessie M. - Maastricht, NLD                                •  agal Modulation of Inflammation
                                                                  V
•  hat Are the Clinical Implications?
  W                                                                Sabbah H. - Detroit, USA
   Natale A. - Austin, USA                                      •  hat Are the Clinical Implications?
                                                                  W
• General Discussion                                              Goldberger J. - Chicago, USA
                                                                • General discussion




                                                                                    www.cardiostim.com                 21
Advance program


Basic Electrophysiology


Friday June 15 / 14:00 - 15:30                                Philippe Coumel Session
SMALL CONDUCTANCE CALCIUM-ACTIVATED                           Introduction: from Mechanism to Process.
POTASSIUM CHANNELS (SK) AND CARDIAC                           Paradigm Shift?
ARRHYTHMIAS                                                   Wednesday June 13 / 09:00 - 10:30
Chair:                                                        ATRIAL FIBRILLATION: DEALING WITH
Lakatta E. - Baltimore, USA
Opthof T. - Utrecht, NLD
                                                              COMPLEXITY
                                                              Chair:
•  hat Are SK Channels?
  W                                                           Guiraudon G.M.- London, CAN
  Chiamvimonvat N. - Chicago, USA                             Klein G. J. - London, CAN
•  K Channels and Ventricular Arrhythmias in Heart Failure
  S
                                                              • ntrinsic Autonomic Cardiac Nervous System: New Physiology
                                                                I
  Chen P- S. - Indianapolis, USA
                                                                or Deregulation? Has Neuroablation Predictable Long-Term
•  K Channels Modulate Cardiogenesis
  S                                                             Effects?
  Liebau S. - Ulm, DEU                                          Cardinal R. - Montreal, CAN
•  K Channels and Genetic Basis of Atrial Fibrillation
  S                                                           •  nderstanding the Complexity of the Substrate of Human AF
                                                                U
  Ellinor P. - Boston, USA                                      Allessie M. - Maastricht, NLD
•  hat Are the Clinical Implications?
  W                                                           •  hen Complexity Beats Ablation? Alternative Interventions to
                                                                W
  Myerburg R. J. - Miami, USA                                   Restore Chronotropic Function, and Stroke Prevention
                                                                Guiraudon G.M. - London, CAN
Friday June 15 / 16:00 - 17:30
ROLE OF miRNAs IN ARRHYTHMIA
SYNDROMES
Chair:
Grunnet M. - Copenhagen, DNK
Boyden P. - New York, USA

•  hy All the Interest in miRNAs?
  W
   Pinto Y. - Amsterdam, NLD
• Hypertrophic Cardiomyopathy
   Ackerman M. - Rochester, USA
•  ong QT Syndrome
   L
   Wilde A. M. - Amsterdam Zuidoost, NLD
• Dilated Cardiomyopathy
   Engelhardt S. - Munich, DEU
•  hat Are the Clinical Implications?
  W
   Roden D. M. - Nashville, USA




22   www.cardiostim.com
Cardiostim 2012


Complex Electrophysiology and Ablation Techniques
Course Directors:
Scheinman M. - San Fransciso, USA
O’Neill M. - London, GBR
Probst V. - Nantes, FRA
Sacher F. - Bordeaux, FRA

Wednesday June 13 / 11:00 - 12:30                                 Wednesday June 13 / 16:00 - 17:30
ATRIAL FIBRILLATION ABLATION I                                    ATRIAL FIBRILLATION ABLATION III
•  echanisms of Atrial Fibrillation. Implication for Ablation
  M                                                               •  ryo Balloon Ablation of AF
                                                                    C
  Strategies                                                        Ellenbogen K. - Richmond, USA
  Nattel S. - Montreal, CAN                                       •  atients Selection for AF Ablation
                                                                    P
•  eal Time Mapping to Guide Atrial Fibrillation Ablation
  R                                                                 O’Neill M. - London, GBR
  Narayan S. - San Diego, USA                                     •  ow to Identify Targets and End-Points for Atrial Fibrillation
                                                                    H
•  MR Imaging:” Does It Have a Role in Atrial Fibrillation
  “                                                                 Ablation?
  Ablation?                                                         Asirvatham S. J. - Rochester, USA
  Marrouche N. F. - Salt Lake City, USA                           •  ong-Term Outcome for Atrial Fibrillation Ablation
                                                                    L
•  trial Fibrillation Ablation for Patients with Long Standing
  A                                                                 Knecht S. - Brussels, BEL
  Persistent Atrial Fibrillation
  Sanders P. - Adelaide, AUS


Wednesday June 13 / 14:00 - 15:30
ATRIAL FIBRILLATION ABLATION II
•  ewer Left Atrial Appendage Occlusion and Ligation Devices
  N
  for Stroke Prevention: Should They Be Part of an Atrial
  Fibrillation Procedure?
  Lee R. J. - San Francisco, USA
•  picardial Ablation of Atrial Fibrillation
  E
  Michaud G. F. - Boston, USA
•  atheter Ablation of Atrial Fibrillation Using a Non-
  C
  Fluoroscopic Sensor Navigation Device
  Hindricks G. - Leipzig, DEU
•  ontact Monitoring and New Ablation Toys
  C
  Wright M. - London, USA




                                                                                        www.cardiostim.com                            23
Advance program


Complex Electrophysiology and Ablation Techniques



Thursday June 14 / 09:00 - 10:30                                       Thursday June 14 / 14:00 - 15:30
ATRIAL FLUTTER ABLATION                                                PAROXYSMAL SUPRAVENTRICULAR
•  nusual forms (Double Loop, Lower Loop and Intra-Isthmus
  U                                                                    TACHYCARDIA ABLATION II
  Reentry)                                                             •  blation of the Patient with Atrio-Fascicular Pathways
                                                                         A
  Mounsey J. P. - Chapel Hill, USA                                       Jackman W. M. - Oklahoma City, USA
•  pproach to the Ablation of Post Atrial Fibrillation Induced Left
  A                                                                    •  blation of Atrial Tachycardia/Accessory Pathways from the
                                                                         A
  Atrial Flutter                                                         Aortic Sinus
  Knecht S. - Brussels, BEL                                              Kuck K. H. - Hamburg, DEU
•  iagnoses and Ablation of Right Sided Flutter
  D                                                                    •  ow to Best Diagnose SVT Mechanisms?
                                                                         H
  Yagi T. - Sendai, JPN                                                  Callans D. - Philadelphia, USA
                                                                       •  resentation of Complex Cases (SVT)
                                                                         P
                                                                         Scheinman M. - San Fransciso, USA



Thursday June 14 / 11:00 - 12:30                                       Thursday June 14 / 16:00 - 17:30
PAROXYSMAL SUPRAVENTRICULAR                                            Interactive session
TACHYCARDIA ABLATION I                                                 • nteractive session
                                                                         I
•  echanisms and Results of Ablative Therapy for Patients with
  M                                                                      Badhwar N. - San Francisco, USA
  Focal Junctional Tachycardia                                           Kalman J. M. - Parkville, AUS
  Cheng J. - Houston, USA                                                Kuck K. H. - Hamburg, DEU
                                                                         Callans D. - Philadelphia, USA
•  blation of Complex ANVRT Circuits
  A
  Badhwar N. - San Francisco, USA
•  iagnoses, Therapy and Results of Ablative Therapy for
  D
  Patients with Manifest or Concealed Nodo-Fascicular
  (Ventricular) Pathways
  Badhwar N. - San Francisco, USA
•  ocalization and Ablation of Atrial Tachycardias
  L
  Kalman J. M. - Parkville, AUS




24   www.cardiostim.com
Cardiostim 2012


Complex Electrophysiology and Ablation Techniques



Friday June 15 / 09:00 - 10:30                                   Friday June 15 / 14:00 - 15:30
VENTRICULAR TACHYCARDIA ABLATION I                               VENTRICULAR TACHYCARDIA ABLATION III -
•  ole of Identifying and Ablating Late Potentials
  R                                                              Debates
  Jaïs P. - Bordeaux, FRA                                        •  atients with 1st Appropriate ICD Shock Should be Treated
                                                                   P
•  ecognition and Ablation of Intraseptal VT
  R                                                                with Ablation
  Bogun F. - Ann Arbor, USA                                        PRO: Sapp J. - Halifax, CAN
•  oes Cardiac MRI Identify the Critical VT Isthmus?
  D                                                                CON: TBD
  Dickfeld T. - Baltimore, USA                                   •  blation of AF: First Line Therapy in Electrical Storms
                                                                   A
•  he Role of Endocardial Unipolar Recordings for VT Ablation
  T                                                                PRO: Boyle N. - Los Angeles, USA
  Callans D. - Philadelphia, USA                                   CON: Coromilas J. - New York, USA




Friday June 15 / 11:00 - 12:30                                   Friday June 15 / 16:00 - 17:30
VENTRICULAR TACHYCARDIA ABLATION II                              VENTRICULAR TACHYCARDIA ABLATION IV
•  atheter Ablation of Fascicular Tachycardia in Practice
  C                                                              •  atheter Ablation of Patients with Arrhythmogenic Right
                                                                   C
  Nogami A. - Kanagawa, JPN                                        Ventricular Dysplasia (ARVD)
•  atheter Ablation of VT from Papillary Muscles
  C                                                                Reddy V. Y. - Boston, USA
  Kay N. - Birmingham, USA                                       •  atheter Ablation of Patients with VT and Systemic Disease
                                                                   C
•  F Ablation in Post MI Patients
  V                                                                (Sarcoid/Amyloid/Iron Overload/Myotonic Dystrophy)
  Snumowski L. - Warsaw, POL                                       Arruda M. - Case Western, USA
•  ong-Term Outcome after VF Ablation
  L                                                              •  blation of the Patient with Ischemic VT
                                                                   A
  Hocini M. - Bordeaux, FRA                                        Soejima K. - Kawasaki, JPN
                                                                 •  ipolar Voltage Map vs. MR for Detection of Myocardial Scar
                                                                   B
                                                                   Gerstenfeld E. P. - Philadelphia, USA




                                                                                     www.cardiostim.com                         25
Advance program


Complex Electrophysiology and Ablation Techniques

Cases Discussion in Electrophysiology
Organized by
Klein G.J. - London, CAN
Sacher F. - Bordeaux-Pessac, FRA
O’Neill M. - London, GBR

Speakers are invited to present 1 or 2 cases they found instructive or challenging. The problem might be diagnostic or related to
ablation complexity.
Speakers should be prepared to be interrupted and participate in dialogue during the presentation and consider this in the length
of their presentation.

Saturday June 16 / 9:00 - 10:30                                     Saturday June 16 / 11:00 - 12:30
THE CHALLENGING CASE - Part I                                       THE CHALLENGING CASE - Part II
Chair:                                                              Chair:
Klein G. J. - London, CAN                                           Klein G. J. - London, CAN
Callans D. - Philadelphia, USA                                      Callans D. - Philadelphia, USA
O’Neill M. - London, GBR                                            O’Neill M. - London, GBR
Skanes A. - London, CAN                                             Skanes A. - London, CAN



State-of-the-Art in the Brugada Syndrome
Organized by
Sacher F. - Bordeaux-Pessac, FRA

Friday June 15 / 09:00 - 10:30                                      Friday June 15 / 11:00 - 12:30
THERAPEUTIC OPTIONS IN BRUGADA                                      UNSOLVED ISSUES IN BRUGADA SYNDROME
SYNDROME                                                            Chair:
                                                                    Wilde A. M. - Amsterdam Zuidoost, NLD
•  isk Stratification in Brugada Syndrome
  R                                                                 Antzelevitch C. - Utica, USA
  Delise P. - Trevise, ITA
•  utcome after ICD Implantation
  O                                                                 •  CN5A: Which Role in Brugada Syndrome?
                                                                      S
  Sacher F. - Bordeaux-Pessac, FRA                                    Probst V. - Nantes, FRA
•  F Ablation in Brugada Syndrome
  V                                                                 •  rugada Syndrome Mechanism: Depolarization/Repolarization
                                                                      B
  Nademanee K. - Los Angeles, USA                                     or Different Entities with a Same ECG Pattern
                                                                      Postema P.G. - Amsterdam, NLD
                                                                    •  alue of Electrophysiological Study for Risk Stratification: The
                                                                      V
                                                                      PRELUDE Study
                                                                      Priori S. G. - Pavia, ITA




26   www.cardiostim.com
Cardiostim 2012


Complex Electrophysiology and Ablation Techniques

Novel Approaches to Apply Mechanistic Insights to Complex Human Arrhythmias
Organized by
E. Pruvot - Lausanne, CHE  S. Narayan - San Diego, USA
Goals: To discuss the implementation and practical application of principles and insights from basic science to understand and treat
human arrhythmias. Because the detailed mapping and tissue analyses for in silico, in vitro and in vivo animal models often cannot
be applied in patients, this session will also discuss technical innovations that have enabled successful translational patient studies.



Thursday June 14 / 14:00 - 15:30                                      Thursday June 14 / 16:00 - 17:30
MECHANISTIC APPROACHES TO COMPLEX                                     MECHANISTICALLY-GUIDED THERAPIES FOR
ARRHYTHMIAS - PART I: REPOLARIZATION                                  HUMAN CARDIAC FIBRILLATION - PART II -
ALTERNANS – TRANSLATING FUNDAMENTAL                                   ATRIAL ARRHYTHMIAS
OBSERVATIONS TO CLINICAL PRACTICE FOR                                 Chair:
ATRIAL AND VENTRICULAR ARRHYTHMIAS                                    Berenfeld O. - Ann Arbor, USA
Chair:
Pruvot E. - Lausanne, CHE                                             •  asic Science of Atrial Fibrillatory Sources: The Role of Rotors
                                                                        B
Narayan S. - San Diego, USA                                             vs Multiple Wavelets
                                                                        Jalife J. - Ann Arbor, USA
•  rom Pulsus to Pulseless: The Saga of Cardiac Repolarization
  F                                                                   •  ocalized Rotors and Focal Beats in Human Atrial Fibrillation
                                                                        L
  Alternans                                                             Narayan S. - San Diego, USA
  Rosenbaum D. S. - Cleveland, USA                                    •  linical Application of Noninvasive Electrocardiographic
                                                                        C
• ntermittent Atrial Tachycardia Promotes Repolarization
  I                                                                     Imaging (ECGI)
  Alternans and Susceptibility to AF in a Free-Behaving Sheep           Cuculich P. - St Louis, USA
  Model                                                               •  lectrogram Correlates of Localized Sources During AF
                                                                        E
  Pruvot E. - Lausanne, CHE                                             Mansour M. - Boston, USA
•  trial Repolarization Alternans as a Dynamic Substrate
  A                                                                   •  ole of Imaging and Ablating Structural Obstacles to Treat
                                                                        R
  Promoting Wavebreaks in Human Paroxysmal and Persistent               Human AF
  AF                                                                    Marrouche N. F. - Salt Lake City, USA
  Narayan S. - San Diego, USA
•  ERCA2A Overexpression as a Molecular Intervention to
  S
  Suppress Repolarization Alternans and Susceptibility of
  Cardiac Fibrillation
  Cutler M. - Cleveland, USA
• ntracardiac Repolarization Alternans/Variability Predicts
  I
  Imminent Ventricular Tachyarrhythmias in ICD Recipients
  Swerdlow C. D. - Los Angeles, USA




                                                                                           www.cardiostim.com                          27
Advance program


Complex Electrophysiology and Ablation Techniques



Friday June 15 / 09:00 - 10:30                                  Computer Modelling
MECHANISTICALLY-GUIDED APPROACHES TO                            Organized by
                                                                Maxime Sermasant - Sophia Antipolis, FRA from INRIA
HUMAN CARDIAC FIBRILLATION - PART III -
                                                                (Institut National de Recherche en Informatique et Automatique)
VENTRICULAR ARRHYTHMIAS
Chair:
Shivkumar K. - San Diego, USA
                                                                Thursday June 14 / 11:00 - 12:30
•  rigger Mechanisms for Human Ventricular Fibrillation
  T                                                             COMPUTATIONAL ELECTROPHYSIOLOGY:
  Knecht S. - Bordeaux, FRA
                                                                NOVEL TOOLS TO IMPROVE CLINICAL
•  ecent Developments in Defibrillation and in Understanding
  R
  Ventricular Fibrillation
                                                                UNDERSTANDING
  Ideker R. - Birmingham, USA                                   Chair:
                                                                Panfilov A. V. - Gent, BEL
•  hat Is the Optimal Mapping Approach to Guide Ablation of
  W
                                                                Rhode K. - London, GBR
  Human Ventricular Tachyarrhythmias?
  Shivkumar K. - Los Angeles, USA
                                                                •  lectrotonic Modulation of Cardiac Repolarization in Health
                                                                  E
•  ignal Processing Approaches to Guide Complex Ablation in
  S
                                                                  and Disease: Insights from a Combined Computational and
  the Atria and Ventricles
                                                                  Experimental Study
  Chen S.A. - Taipei, TWN
                                                                  Bernus O. - Bordeaux-Pessac, FRA
•  ignal Processing Insights into the Mechanisms of Human
  S
                                                                •  lectro-Mechanical Interaction – Is This Something the
                                                                  E
  Ventricular Arrhythmias
                                                                  Clinical Electrophysiologist Has to Care about or Is This only of
  Krummen D.E. - San Diego, USA
                                                                  Interest to the Cellular Researcher?
                                                                  Bijnens B. - Barcelona, ESP
                                                                •  lectrical and Structural Characteristics of Border Zone in
                                                                  E
                                                                  Infarcted Swine: Insights from 3D MR Image-Based Computer
                                                                  Models, Histopathology and EP Data
                                                                  Pop M. - Toronto, CAN
                                                                •  ardiac Radiofrequency Ablation Planning from Personalized
                                                                  C
                                                                  Biophysical Models
                                                                  Delingette H. - Sophia-Antipolis, FRA




28   www.cardiostim.com
Cardiostim 2012


Treatments of Atrial Fibrillation

Advances and Controversies in Atrial Fibrillation (ACAF)
Chairman:
Naccarelli G. V. - Hershey, USA
Blanc J.J. - Brest, FRA
Lévy S. - Marseille, FRA

Unrestricted Educational Support: sanofi aventis


Thursday June 14 / 09:00 - 10:30                               Thursday June 14 / 14:00 - 15:30
ATRIAL FIBRILLATION I                                          ATRIAL FIBRILLATION III
Chair:                                                         Chair:
Naccarelli G. V. - Hershey, USA                                Santini M. - Rome, ITA
Boriani G. - Bologna, ITA                                      Breithardt G. - Münster, DEU

•  arly Attempts at Rhythm Control Slows Progression of AF
  E                                                            •  ovel Anticoagulants: Where Are We in 2012?
                                                                 N
  Crijns H. J. - Maastricht, NLD                                 Naccarelli G. V. - Hershey, USA
•  as Basic Science Helped Us Develop Better Pharmacologic
  H                                                            •  an Newer Anticoagulants Be Used Safely for Cardioversion
                                                                 C
  and Ablative Therapies for AF?                                 of AF Patients?
  Allessie M. - Maastricht, NLD                                  Aliot E. - Nancy, FRA
•  pstream Therapy of AF – Is It All over but the Shouting?
  U                                                            •  ntiarrhythmic/Anticoagulant Drug Interactions: What Do We
                                                                 A
  Dorian P. - Toronto, CAN                                       Know?
                                                                 Tamargo J. - Madrid, ESP


Thursday June 14 / 11:00 - 12:30                               Thursday June 14 / 16:00 - 17:30
ATRIAL FIBRILLATION II                                         ATRIAL FIBRILLATION IV
Chair:                                                         Chair:
van Gelder I. C. - Groningen, NLD                              Lévy S. - Marseille, FRA
Capucci A. - Ancona, ITA                                       Vardas P. E. - Heraklion, GRC

•  ronedarone in 2012: What is New?
  D                                                            •  symptomatic AF: Prognostic Implications
                                                                 A
  Le Heuzey J. Y. - Paris , FRA                                  Blanc J. J. - Brest, FRA
•  ALLAS: Why Was It Performed? Where Are We?
  P                                                            • s Catheter Ablation of AF Prothrombotic or Antithrombotic?
                                                                 I
  Hohnloser S. - Frankfurt, DEU                                  Packer D. L. - Rochester, USA
•  ronedarone and Ranolazine: Is a Combination Drug a Good
  D                                                            •  ole of Novel Anticoagulants During AF Ablation Procedures?
                                                                 R
  Idea ?                                                         Cappato R. - San Donato Milanese (MI), ITA
  Antzelevitch C. - Utica, USA




                                                                                   www.cardiostim.com                      29
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Cardiostim 2012 Advance Program

  • 1. CARDIOSTIM 2010 A dva n ce p rogra m 18th World Congress in Cardiac Electrophysiology & C a r d i a c Te c h n i q u e s June 13 > 16 I 2012 Nice • FrAncE Painting by Françoise Persil­­­­lon Advance program www.cardiostim.com In collaboration with www.cardiostim.fr 1
  • 2.
  • 3. Cardiostim 2012 éditorial European Heart Rhythm Association (EHRA) Program A message Wednesday June 13 / 00:00 AM Wednesday June 13 / 00:00 AM from the Chairman of Cardiostim CARDIAC STEM CELLS AND GENE THERAPY NEW IMAGING TECHNIQUES Chair: Chair: Cohen I. - Stony Brook, USA Kalman J. - Melbourne, AUS Fast V. - Birmingham, USA Mazgalev T.N. - Cleveland, USA • aking Hearts Regenerate M • lectrocardiographic Imaging to Understand Arrhythmia E Dear Colleagues, DearCHE Pedrazzini T. - Lausanne, Friends, Mechanisms • ardiac Differentiation of Human Keratinocytes Derived from C Rudy Y. - St. Louis, USA Today is already tomorrow! Plucked Hair Follicles • imulations to Predict Sites of VT Ablation S Trayanova N. A. - come. Advances In Binah O. - were announcing revolutions in the Electrophysiology world for the years to Baltimore, USA are now on the way, and 2010, we Haifa, ISR • RI for Risk Prediction of Arrhythmogenic Areas M their first applications Stem Cells from Patients the 2012 edition of Cardiostim! • nduced Pluripotent will be discussed during with Inherited I Halperin H. - saved by USA Routine ablation procedures for VT/VF, especially during electrical storms in patientsBaltimore, their ICD, robotic and 3D mapping Arrhythmias and navigation - Madison, USA • hat Are the Clinical Implications? management, transeptal, W new anticoagulants in AF January C. T. for EP and ablation techniques, contact force control, pericardialthe robotic approaches to the left ventricle for CRT, cardiac simulation - Mannheim, DEU arrhythmia mechanisms and • hat Are or Clinical Implications? W Borggrefe M. for understanding CRT, among many others, are some of the major topics that will be introduced Discussion • eneral and debated! G Rosen M. R. - New York, USA New recommendations on palpitation management and CRT implantation and follow-up will be presented. Formerly recognized • General Discussion indications will be revisited, such as vaso-vagal syncope, hypertrophic cardiomyopathy or Brugada syndrome. Lots of debates will be organized as shows and you’ll be able to give your opinion through voting systems in many of the programs settled by the most famous experts. What is unique in Cardiostim is the atmosphere that brings more and more people to this friendly meeting where attendees can freely express their opinion. That is probably why, despite the international financial crisis, more than a thousand abstracts have been received from all over the world, and especially from countries that were not present until now in our congress, demonstrating the interest of colleagues keen to come to Nice to present their data and debate! Congratulations to all authors for their scientific contribution. The EHRA Program Committee members, conducted by Andreas Goette (Leipzig – Germany), participated actively in the abstract selection in addition to the Cardiostim members. Consequently, each abstract has been reviewed by at least 6 experts. The Selection Committee rejected 43 % abstracts overall. This year, a smaller number of oral abstract sessions is proposed to enhance the quality of the presented material. I must congratulate and thank everyone for these difficult tasks! As can be seen along this Advance Program, the global result of the combination of EHRA sessions with the traditional programs proposed by our American friends and the Cardiostim Team is a high standard program that one will remind as the most complete and attractive ever! Our task is to translate this knowledge into understandable and useful information for clinical practice. This is why Cardiostim also proposes educational sessions based on case presentations in the general program as well as dedicated sessions. With the same logics, specific sessions will be dedicated to technicians and nurses. Next June, you will enjoy Cardiostim! The platform to consult and free download ECG and Epidemiology data Philippe Ritter - Chairman http://epdatabank.cardiostim.com www.cardiostim.com 3
  • 4. springermedizin.de Up-to-date – Qualified – Online Clinical Research in Cardiology • Current and competent survey on the diagnosis and therapy of heart and vascular diseases • Impact Factor 2010: 3.466, rank 31/114 (Journal Citation Reports ® Thomson Reuters) • Official Journal of the German Cardiac Society www.crc.springer.de Extensive online archive! 050357
  • 5. Cardiostim 2012 Congress Highlights in 2012 THE EHRA PROGRAM An extensive program was designed by the Scientific Program Committee of EHRA, and will include a total number of 30 sessions. HIGH-TECH ADVANCES Among many others, four sessions will focus on new technologies that will impact our practice in the future with the following topics: understanding of arrhythmia mechanisms and signal processing, computer simulation in electrophysiology and CRT. HIGH STANDARD EDUCATION Educational material is proposed in all programs, based on Case presentations. In the EP and ablation section, a specific program is proposed by George Klein on Saturday June 16. In addition a Program is given in French on devices, and two sessions are dedicated to technicians and nurses. EPDatabank by cardiostim New in Cardiostim! Educational material is available on http://epdatabank.cardiostim.com for your own purposes. Epidemiologic information, ECG tracings, EGMs, etc… can be downloaded for free! Don’t hesitate to submit yours! The platform to consult and free download ECG and Epidemiology data http://epdatabank.cardiostim.com www.cardiostim.com 5
  • 6. Advance program Scientific Organizing Committee CARDIOSTIM TEAM Philippe Ritter (Bordeaux, FRA) Pierre Bordachar, Stéphane Garrigue, Sylvain Reuter, Frédéric Sacher (Bordeaux, FRA), Mark O’Neill (London, GBR), Vincent Probst (Nantes, FRA) David Hayes (Rochester, USA) J.Claude Daubert (Rennes, FRA) Douglas Zipes (Indianapolis, USA) J.Jacques Blanc (Brest, FRA) European Heart Rhythm Association (EHRA) President: Angelo Auricchio (Lugano, CHE) Europace 2013 Program Committee Chairman: Andreas Götte (Magdeburg, DEU) Vice-Chairman: John M. Morgan (Southampton, GBR) Preparation Committee for Scientific Programs To date, will be implemented as we go along Abi-Samra F. M. USA Butter C. DEU Dobrev D. DEU Gorenek B. TUR Adragao P. PRT Calkins H. USA Dodinot B. FRA Gras D. FRA Aliot E. FRA Callans D. USA Dolan B. USA Grunnet M. DNK Allessie M. NLD Camm A. J. GBR Dorian P. CAN Guiraudon G. M. CAN Alonso C. FRA Cannom D. S. USA Dubner S. ARG Guirgis M. FRA Amman P CHE Cappato R. ITA Duffy H. USA Gulizia M. ITA Antzelevitch C. USA Capucci A. ITA Duytschaever M. BEL Hachiya H. JPN Arnar D ICE Carlson M. D. USA Efimov I. R. USA Haigney M. USA Asirvatham S. J. USA Cazeau S. FRA Ehrlich J. DEU Haines D. E. USA Atie J. BRA Cha Y. M. USA Ellenbogen K. USA Haïssaguerre M. FRA Atienza F. ESP Chen S. A. TWN El-Sherif N. USA Halimi F FRA Auricchio A. CHE Cheng J. USA Epstein L. USA Hammill S. C. USA Badhwar N. USA Chirife R. ARG Erdogan A. DEU Hasin Y. ISR Behrenbeck T. USA Clemmensen P.M. DNK Ernst S. DEU Hastrup Svendse J DNK Belott P. H. USA Cohen I. USA Exner D. CAN Hatala R. CZE Benditt D. G. USA Cooke D. USA Ezekowitz M. D. USA Hayes D. USA Berenfeld O. USA Coronel R. NLD Fast V. USA Healey J. S. USA Biffi M. ITA Corrado D. ITA Fedorov V. USA Heidbüchel H. BEL Binner L. DEU Cowie M. GBR Fermont L. FRA Helland J. USA Blanc J. J. FRA Crijns H. J. NLD Fernandez Lozano I. ESP Hill M. USA Blomström-Lundqvist C. WE S Curnis A. ITA Fishman G. I. USA Hindricks G. DEU Boersma L. NLD Danchin N. FRA Flammang D. FRA Hirao K. JPN Bongiorni M. G. ITA Darrel F. GBR Franz M. USA Ho I. USA Bordachar P. FRA Daubert J. C. FRA Friedman P. A. USA Hocini M. FRA Borggrefe M. DEU Davies W. GBR Furniss S. GBR Hoffmann E. DEU Boriani G. ITA Davy J. M. FRA Gaita F. ITA Hohnloser S. DEU Botto G. ITA De Chillou C. FRA Gammage M. GBR Hombach V. DEU Boveda S. FRA De Roy L. BEL Garrigue S. FRA Hornberger L. K. USA Boyden P. A. USA Deaton C GBR Geelen P. BEL Husser D DEU Brachmann J DEU Defaye P. FRA Geller C. DEU Iacopino S. ITA Braunschweig F. SWE Deharo J. C. FRA Gerstenfeld E. USA Ideker R. E. USA Breithardt G. DEU Della Bella P. ITA Gilmour R. USA Ishikawa T. JPN Brignole M. ITA Delnoy P. P. NLD Giudici M. USA Israel C. W. DEU Brugada P. BEL Dickstein K. NOR Goette A. DEU Jackman W. M. USA Burri H. CHE Diener H. C. DEU Gold M. USA Jahangir A. USA 6 www.cardiostim.com
  • 7. Cardiostim 2012 Jaïs P. FRA McGann C. USA Rhode K. GBR Sternick E. BRA Jalife J. USA McKenna W. J. GBR Ricci R. ITA Stevenson W. G. USA Janse M. NLD McVenes R. USA Rich M. USA Sticherling C. CHE Jansens J. L. BEL Meine M. NLD Rinaldi A. ITA Stone P. H. USA Jauvert G. FRA Meinertz T. DEU Rizzo G. ITA Stotts L. USA Jordaens L. NLD Mohr F. W. DEU Roberts P. GBR Suga C. JPN Jung W DEU Molina L. MEX Roden D. M. USA Sulke N. USA Kaab S. DEU Mont L. ESP Rodriguez E. ESP Sutton R. MCO Kacet S. FRA Moorman A. NLD Roguin A. ISR Svendsen J. H. DNK Kalifa J. USA Morgan J. M. GBR Rohr S. CHE Szili-Török T. NLD Kalman J. M. AUS Morillo C. CAN Ronaszéki A. HUN Taborsky M. CZE Kautzner J. CZE Moss A. J. USA Rosen M. R. USA Tanel R. USA Kay N. USA Munger T. T. USA Rosenbaum D. S. USA Thambo J. B. FRA Keane D. USA Murgatroyd F. D. GBR Rowland E. GBR Thermistocles S. ITA Kennergren C. SWE Myerburg R. J. USA Rozkovec A. DEU Thibault B. CAN Kenny R. A. IRL Naccarelli G. V. USA Rudy Y. USA Thiene G. ITA Kirchhof P. DEU Nademanee K. USA Ruffy R. USA Thijs V. BEL Kleber A. CHE Nakagawa H. USA Ruiz-Granell R. ESP Tomaselli G. F. USA Klein G. J. CAN Nakazato Y. JPN Ruskin J. N. USA Tondo C. ITA Klein H. DEU Nanthakumar K. CAN Sacher F. FRA Trayanova N. USA Klingenheben T. DEU Narayan S. M. USA Sadoul N. FRA Treede H. DEU Klug D. FRA Natale A. USA Saffitz J. E. USA Tristani-Firouzi M. USA Knecht S. BEL Nattel S. CAN Saghy L HUN Tse H. F. CHN Knight B. USA Nerbonne J. USA Saksena S. USA Tseng G. N. USA Kottkamp H. DEU Neumann T. DEU Salama G. USA Tubaro M. ITA Krieger D. DNK Neuzil P. CZE Sanders P. FRA Turitto G. USA Krueger M. DEU Nielsen J. C. DNK Sanguinetti M. USA Valiunas V. USA Kuck K. H. DEU Nogami A. JPN Santini M. ITA van Gelder I. C. NLD Kusumoto F. USA Norihisa T. JPN Santomauro M. ITA Van Gelder B. NLD La Rovere M. T. ITA Olgin J. USA Savelieva I. GBR Van Wagoner D. R. USA Lakatta E. USA Olshansky B. USA Saxon L. USA Vardas P. E. GRC Lau C. P. CHN O’Neill M. GBR Schaerf R. USA Varma N. USA Lazarus A. FRA Opthof T. NLD Schalij M. NLD Verrier R. L. CAN Lazzara R. USA Oseroff O. ARG Scheinman M. USA Vesin J. M. CHE Le Heuzey J. Y. FRA Oto A. TUR Schilling R. DEU Viskin S. ISR Leclercq C. FRA Ovsyshcher E. ISR Schleich J. M. FRA Vlietstra R. USA Leclercq J-F FRA Oyarzun R CHL Schmidt B. DEU Vogt J. DEU Lee H. C. USA Packer D. L. USA Schmidt G. DEU Vohra J. K. AUS Leenhardt A. FRA Padeletti L. ITA Schotten U. NLD Vos M. NLD Lévy S. FRA Page R. L. USA Schuger C. USA Vrints C. BEL Lewalter T. DEU Panfilov A. V. NLD Schumacher B. DEU Waldo A. L. USA Lickfett L. DEU Pappone C. ITA Schwartz P. J. ITA Wallentin L. DEU Linde C. M. SWE Parkhomenko A. UKR Schweikert R. USA Weiss J. USA Linker N. J. GBR Parry S. W. GBR Schwitter J. CHE Wellens H. J. NLD Lip GYH GBR Pedretti R. ITA Semisarian C. AUS Wieling W. NLD Locati E. ITA Pelleg A. USA Sermasant M. FRA Wilber D. J. USA Loh P. NDL Piccini J. USA Sethi K. IND Wilde A. M. NLD London B. USA Piorkowski C. DEU Shah D. CHE Wilkoff B. L. USA Love C. J. USA Poelzing S. DEU Shaw R. USA Willems S. DEU Lubinski A. POL Pokushalov E RUS Shen W. USA Wolpert C. DEU Mabo P. FRA Poole J. E. USA Shivkumar K. USA Xhaet O. FRA Maier L. DEU Pratt C. M. USA Shoda M. JPN Yamada K. USA Malik M. GBR Prinzen F. W. NLD Simantirakis E. N. GRC Yamane T. JPN Manolis A. S. GRC Priori S. G. ITA Siu D. CHN Yang Y. USA Mansour M. USA Pruvot E. CHE Sloman G. AUS Yu C. M. CHN Mantovan R. ITA Prystowsky E. N. USA Smith N. GBR Zannad F. FRA Marcus F. USA Puererfellner H. AUT Sogaard P. DNK Zareba W. USA Markijarvi M. FIN Quinn T. GBR Sommer T. DEU Zaza A. ITA Maron B. USA Rasmussen L. H. DNK Sperzel J. DEU Zeppenfeld K. NLD Marrouche N. F. USA Raviele A. ITA Squarcia U. ITA Zieman S. USA Martinek M. AUT Rea R. USA Steinbeck G. DEU Zipes D.P. USA Mazgalev T. N. USA Reddy V. Y. USA Steinberg J. USA Zupan I. SVN McCarty J. USA Revishvilli A. RUS Steinhaus D. USA McElderry T. USA Reynolds D. W. USA Stern S. ISR www.cardiostim.com 7
  • 8. Advance program In collaboration with • European Heart Rhythm Association (EHRA) • Société Française de Cardiologie • European Society of Cardiology • Heart Rhythm Society (HRS) • World Society of Arrhythmias WSA/ICPES • International Society for Holter and Noninvasive Electrocardiology (ISHNE) • Groupe Français d’Electrophysiologie et de Stimulation Cardiaque de la Société Française de Cardiologie • Sociedad Asociación Civil Argentina de Estimulación Cardiaca (SADEC) • Asian-Pacific Society of Cardiology • Brazilian Society of Cardiology • Latin-American Society of Pacing and Electrophysiology (SOLAECE) • Artificial Cardiac Electrostimulation Department of the Brazilian Cardiac Surgery Group (DECA) • Associazione Italiana di Aritmologia e Cardiostimolazione (AIAC) • Mediterranean Society of Pacing and Electrophysiology (MESPE) • he RETAC Group (Reunion of European countries for the Treatment of Arrhythmias in Cardiology/Réseau Européen T pour le Traitement des Arythmies Cardiaques) CME ACCREDITATION EHRA SESSIONS at CARDIOSTIM 2012 are currently under review for accreditation by the European Board for Accreditation in Cardiology (EBAC) for external CME credits. The accreditation results will be announced online and in the final program. Subscribe to Cardiostim newsletter ✓ on www.cardiostim.com 8 www.cardiostim.com
  • 9. Cardiostim 2012 Contents European Heart Rhythm Association (EHRA) Program.............................................................................................. P. 10 Basic Electrophysiology.............................................................................................................................................. P. 19 Complex Electrophysiology and Ablation Techniques.............................................................................................. P. 23 • Novel Approaches to Apply Mechanistic Insights to Complex Human Arrhythmias Treatments for Atrial Fibrillation................................................................................................................................. P. 29 • Advances and Controversies in Atrial Fibrillation (ACAF) Noninvasive Electrocardiology.................................................................................................................................... P. 30 • Educational Symposium of International Society for Holter and Noninvasive Electrocardiology (ISHNE) Main Trials in the Management of Atrial Fibrillation.................................................................................................. P. 34 Acute Cardiac Care: Management of SCD.................................................................................................................. P. 35 Pacing, ICDs and CRT.................................................................................................................................................. P. 36 Leads............................................................................................................................................................................ P. 43 Associate Symposia.................................................................................................................................................... P. 45 • Cardiostim / HRS Joint Session • Cardiopace • Vaso Vagal Syncope • Geriatric Cardiology • Asia Pacific Cardiostim Symposium • Palpitations • Fetal Cardiology Symposium • Pediatric Cardiac Electrophysiology • Cardiostim-JHRS Joint Session • Syncope • ICE Program • Italian Cardiostim Symposium • EPIC Alliance Industry Symposia....................................................................................................................................................... P. 53 Symposium STIMUPRAT.............................................................................................................................................. P. 59 The publisher and the Cardiostim organization disclaim any liability for errors or omissions that may come to light, despite the care taken in the production of this Advance Program. www.cardiostim.com 9
  • 10. Advance program European Heart Rhythm Association (EHRA) Program Organized by the Scientific Committee of EHRA, Coordination, Program Committee Andreas Götte - Magdeburg, DEU Wednesday June 13 / 9:00 - 10:30 Wednesday June 13 / 9:00 - 10:30 CRT IN THE 21ST CENTURY. WHAT DO WE NEW INSIGHTS IN BASICS OF ARRHYTHMIAS HAVE NOW? STATUS QUO AND QUO VADIS? Chair: Chair: Crijns H. J. - Maastricht, NLD Boriani G. - Bologna, ITA Savelieva I. - London, GBR Kuck K. H. - Hamburg, DEU • alcium Handling and Arrhythmias: A Link to Be Targeted C • RT in Ischemic Heart Failure Patients: From Cell Function to C Zaza A. - Milano, ITA Clinical Outcome • Nodes» in the Arrhythmia Pathogenetic Network « Auricchio A. - Lugano, CHE Schotten U. - Maastricht, NLD • RT in Patients with Atrial Fibrillation C • itochondrial Dysfunction and Arrhythmias M Vardas P. E. - Heraklion, GRC O’Rourke B. - Baltimore, USA • wo Years with New Guidelines. Do We Have Unresolved T • linical Evidence and Possible Therapy of These Arrhythmias C Questions? Van Gelder I. C. - Groningen, NLD Dickstein K. - Stavanger, NOR • RT in Narrow QRS C Ponikowski P. - Wroclaw, POL Wednesday June 13 / 9:00 - 10:30 Wednesday June 13 / 9:00 - 10:30 PACEMAKER THERAPY IN YEAR 2012 ION CHANNELOPATHIES Chair: Chair: Simantirakis E. N. - Heraklion, GRC Jalife J. - Ann Arbor, USA Oyarzun R. - Santiago, CHL Kaab S. - Munchen, DEU • ow Important Is Minimization of RV Pacing? H • ong QT Syndrome - Types and Therapies L Israel C. W. - Bielefeld, DEU Priori S. G. - Pavia, ITA • R Safe Pacemakers M • rugada Syndrome - Place of Ion Channel Antiarrhythmic B Davy J. M. - Montpellier, FRA Drugs Wolpert C. - Mannheim, DEU • here in the RV Should Ventricular Pacing Be Applied? W Butter C. - Bernau, DEU • Wave Syndromes J Antzelevitch C. - Utica, USA • hould AAI Pacing Be Considered Obsolete? S Nielsen J. C. - Aarhus, DNK • diopathic Ventricular Fibrillation - Does It Exist? I Wilde A. M. - Amsterdam Zuidoost, NLD 10 www.cardiostim.com
  • 11. Cardiostim 2012 European Heart Rhythm Association (EHRA) Program Wednesday June 13 / 11:00 - 12:30 Wednesday June 13 / 11:00 - 12:30 CRT: READING THE GUIDELINES WHAT A DEVICE SPECIALIST NEEDS TO KNOW Chair: ABOUT HEART FAILURE Auricchio A. - Lugano, CHE Chair: Kirchhof P. - Birmingham, GBR Daubert J. C. - Rennes, FRA Ponikowski P. - Wroclaw, POL • RT in Mild Heart Failure C Linde C. M. - Stockholm, SWE • acing in Heart Failure: What Happens on the Cellular Level? P • RT in Atrial Fibrillation C Vanderheyden M. - Aalst, BEL Sutton R. - Monaco, MCO • ptimal Medical Treatment in Heart Failure O • RT in Patients with Conventional Pacemaker Indications C Cowie M. - London, GBR Burri H. - Geneva, CHE • he Device Patient with End Stage Heart Failure T • RT in Clinical Practice: The European CRT Survey C Fruhwald F. - Graz, AUT Dickstein K. - Stavanger , NOR • ole of Implantable Sensors in Heart Failure Management R Braunschweig F. - Stockholm, SWE Wednesday June 13 / 11:00 - 12:30 PURKINJE FIBERS AND VENTRICULAR ARRHYTHMIAS Chair: Kuck K. H. - Hamburg, DEU Leclercq J. F. - Levallois, FRA • rrhythmia of Purkinje Fibers: Specificity of Cellular A Mechanisms Ehrlich J. - Frankfurt, DEU • ffect of Antiarrhythmic Drugs on the Purkinje Network: E Electrophysiological and Pharmacological Aspects Vos M. - Utrecht, NLD • blation of Polymorphic VT in Patients with Structural Heart A Disease TBD • diopathic VF Originating from the Purkinje Network: Ablation I Targets and Long-Term Follow-Up Knecht S. - Brussels, BEL www.cardiostim.com 11
  • 12. Advance program European Heart Rhythm Association (EHRA) Program Wednesday June 13 / 14:00 - 15:30 Wednesday June 13 / 16:00 - 17:30 NEW EHRA DOCUMENTS ICD THERAPY IN YEAR 2012 Chair: Chair: Raviele A. - Venice, ITA Garrigue S. - Bordeaux, FRA Svendsen J. H. - Copenhagen, DNK • alpitations P Raviele A. - Venice, ITA • efibrillation Testing during Implant: To Do or Not to Do? D • leeding Risk B Baensch D. - Rostock, DEU Lip G. Y. - Birmingham, GBR • ow to Reduce Inappropriate Shock Therapy H • ICD for Life’ Initiative-Fighting against Sudden Cardiac Death ‘ Wolpert C. - Mannheim, DEU in Emerging Economies. • eliability of Implantable Devices and Leads - Are They Good R Merkely B. - Budapest, HUN Enough? • enetic Testing G Steinhaus D. M. - Mounds View, USA Priori S. G. - Pavia, ITA • ow Should We Program Tachy Parameters in ICDs. H Zupan I. - Ljubljana, SVN Wednesday June 13 / 14:00 - 15:30 Wednesday June 13 / 16:00 - 17:30 SUDDEN CARDIAC DEATH IN THE YOUNG STATE-OF-THE ART ON VENTRICULAR Chair: TACHYCARDIA ABLATION Heidbüchel H. - Leuven, BEL Chair: Morgan J. M. - Southampton, GBR De Chillou C. - Nancy, FRA Wellens H. J. - Maastrisht, NLD • utopsy Rate and Cause of Death in the Young: A National A Study from Denmark • ndocardial Catheter Ablation of Monomorphic VT: From E Winkel B. G. - Copenhagen, DNK Bench to EP Lab • rugada Syndrome: Not as Dangerous as First Assumed? B Atie J. - Rio do Janeiro, BRA Borggrefe M. - Mannheim, DEU • picardial Approach: A First Line Therapy? E • ow Should We Make a Work-Up in Young Cardiac Arrest H Della Bella P. - Milano, ITA Survivors? • ew Mapping and Ablation Strategies for Catheter Ablation of N Braunschweig F. - Stockholm, SWE VT in Patients with Dilated Cardiomyopathies • oronary Abnormalities and Sudden Cardiac Death C Piorkowski C. - Leipzig, DEU Ho S. Y. - London, GBR • ombined Ablation Endo-Epicardial Approach for VT Ablation C Kottkamp H. - Zurich, CHE 12 www.cardiostim.com
  • 13. Cardiostim 2012 European Heart Rhythm Association (EHRA) Program Thursday June 14 / 09:00 - 10:30 Thursday June 14 / 11:00 - 12:30 PREVENTING SUDDEN CARDIAC DEATH WITH HIGHLIGHTS FROM EUROPACE 2011: DEVICE RF ABLATION THERAPY, INTERVENTIONAL EP AND MEDICAL Chair: THERAPY Haïssaguerre M. - Pessac, FRA Chair: Mont L. - Barcelona, ESP Auricchio A. - Lugano, CHE Hindricks G. - Leipzig, DEU • apping and Ablation of Idiopathic Ventricular Fibrillation M Sacher F. - Bordeaux, FRA • nterventional EP I • revention of VF Episodes in Brugada Syndrome by Catheter P Merino J. L. - Madrid, ESP Ablation • harmacotherapy P Merino J. L. - Madrid, ESP Camm A. J. - London, GBR • ombined Endocardial and Epicardial Ablation in Patients with C • acing P ARVD Vardas P. E. - Heraklion, GRC Wissner E. - Hamburg, DEU • efibrillation and CRT-D D • atheter Ablation of Ventricular Electrical Storms C Wolpert C. - Mannheim, DEU Atie J. - Rio do Janeiro, BRA Thursday June 14 / 09:00 - 10:30 STROKE PREVENTION IN ATRIAL FIBRILLATION: STATE-OF-THE ART AND NEW CONCEPTS Chair: Camm A. J. - London, GBR Rasmussen L. H. - Aalborg, DNK • asic Science Insights into the Prothrombotic State in Atrial B Fibrillation De Caterina R. - Chieti, ITA • linical Trial Update - What Do the RELY, ROCKET, C ARISTOTLE and AVERROES Trials Tell Us? Lip G. Y. - Birmingham, GBR • oes Aspirin Still Have a Role in Atrial Fibrillation? D Grond M. - Berlin, DEU • hat Should the New Guideline Revisions on Stroke W Prevention Look Like? Kirchhof P. - Birmingham, GBR www.cardiostim.com 13
  • 14. Advance program European Heart Rhythm Association (EHRA) Program Thursday June 14 / 14:00 - 15:30 Thursday June 14 / 16:00 - 17:30 CRT IMPLANTATION AND FOLLOW-UP: THE CHALLENGES OF THE ASYMPTOMATIC EHRA-HRS CONSENSUS STATEMENT PATIENT IN HEREDITARY SYNDROMES Chair: Chair: Daubert J.C. - Rennes, FRA Priori S. G. - Pavia, ITA Saxon L. - Los Angeles, USA Wolpert C. - Mannheim, DEU • re-Implant Evaluation P • symptomatic Patient with Long QT Syndrome A Brignole M. - Lavagna, ITA Schulze-Bahr E. - Munster, DEU • mplantation I • symptomatic Patient with Brugada Syndrome A Singh J. - Boston, USA Brugada Terradellas P. - Brussels, BEL • re-Discharge Evaluation P • symptomatic Patient with Early Repolarization Syndrome A Leclercq C. - Rennes, FRA Haïssaguerre M. - Bordeaux, FRA • evice and Heart Failure Follow-Up D Israel C.W. - Frankfurt, DEU • symptomatic Patient with Catecholaminergic Polymorphic VT A • esponse to CRT R Wanguemert Perez F. - Las Palmas, ESP Gold M. - Charleston, USA • pecific Issues S Saxon L. - Los Angeles, USA Thursday June 14 / 16:00 - 17:30 Thursday June 14 / 16:00 - 17:30 CONTEMPORARY CONSIDERATIONS BASED ON TRANSLATIONAL APPROACHES IN ATRIAL TECHNOLOGICAL DEVELOPMENTS IN CARDIAC FIBRILLATION PACING Chair: Chair: Zaza A. - Milano, ITA Botto G. - Como, ITA Goette A. - Magdeburg, DEU Sutton R. - Monte Carlo, MCO • enes and Mutations in Patients with Lone Atrial Fibrillation: G • hould All Permanent Pacemakers Be MRI Compatible? S Do They Matter? Santini M. - Roma, ITA Olesen M. - Copenhagen, DNK • s Telemonitoring a New Necessity? I • onic Remodelling: From Bench to Bedside I Burri H. - Geneva, CHE Van Gelder I. C. - Groningen, NLD • eadless Pacing: A Step Forward? L • tructural Remodeling: Which Impact for Catheter Ablation? S Roberts P. - Southampton, GBR Schotten U. - Maastricht, NLD • iological Pacemakers: A Futuristic Approach? B • trial and Ventricular Oxidatives Stress during Atrial A Israel C. W. - Bielefeld, DEU Fibrillation Lendeckel U. - Greifswald, DEU 14 www.cardiostim.com
  • 15. Cardiostim 2012 European Heart Rhythm Association (EHRA) Program Friday June 15 / 09:00 - 10:30 Friday June 15 / 11:00 - 12:30 IMPROVING OUTCOMES IN THE CATHETER COMPLICATIONS RELATED TO ATRIAL ABLATION OF ATRIAL FIBRILLATION FIBRILLATION CATHETER ABLATION Chair: Chair: Kautzner J. - Praha, CZE Gaita F. - Asti, ITA Kuck K. H. - Hamburg, DEU Hatala R. - Bratislava, SVK • enervation of the Heart. The Role of gP Ablation in Atrial D • revalence and Predictors of Complications of Radiofrequency P Fibrillation Treatment Catheter Ablation for Atrial Fibrillation Pokushalov E. - Novosibirsk, RUS Kautzner J. - Praha, CZE • arly Ablation of Atrial Fibrillation. Would We Have Better E • atheter Ablation on Uninterrupted Warfarin: Is It Safe? C Long-Term Results in the Future? Schilling R. - London, GBR Kirchhof P. - Birmingham, GBR • ncidence of Silent Cerebral Thromboembolic Lesions after I • atheter Ablation of the Long-Standing Persistent Atrial C Atrial Fibrillation Ablation: Predictive Factors? Fibrillation. Where We Are Now? Scaglione M. - Asti, ITA Willems S. - Hamburg, DEU • ong-Term Rates of Death, Stroke, and Dementia Following L • urrent Standard of Care in Atrial Fibrillation Ablation C Atrial Fibrillation Ablation Jaïs P. - Bordeaux, FRA Day J. - Salt Lake City, USA Friday June 15 / 09:00 - 10:30 Friday June 15 / 11:00 - 12:30 THE COMPLEX PACEMAKER IMPLANTATION CONTINUOUS MONITORING IN ATRIAL Chair: FIBRILLATION MANAGEMENT. NEW SCIENCE Davy J. M. - Montpellier, FRA OR NEW TRUTH? Ponikowski P. - Wroclaw, POL Chair: Lewalter T. - Bonn, DEU • evice Implant in Case of Subclavian Vein Occlusion D Zupan I. - Ljubljana, SVN Bracke F. - Eindhoven, NLD • mplantation of a Pacing System in GUCH Patients I • ymptomatic/Asymptomatic Events after AF Ablation S Morgan J. M. - Southampton, GBR Hindricks G. - Leipzig, DEU • acing Considerations in Pediatric Patients P • nticoagulation/Antiarrhythmic Management after AF Ablation A Cantu F. - Bergamo, ITA Kirchhof P. - Birmingham, GBR • acemaker Therapy after TAVI Procedure P • F Burden in Assessment of Long-Term Success after AF A Wissner E. - Hamburg, DEU Ablation Puererfellner H. - Linz, AUT • anagement of Early Post-Operative Period. Who Will Need M Early Reablation? Pokushalov E. - Novosibirsk, RUS www.cardiostim.com 15
  • 16. Advance program European Heart Rhythm Association (EHRA) Program Friday June 15 / 14:00 - 15:30 Friday June 15 / 16:00 - 17:30 ADVANCES IN ROBOTIC AND 3D MAPPING DIAGNOSTIC EVALUATION OF SYNCOPE IN TECHNOLOGIES FOR ATRIAL FIBRILLATION SPECIAL PATIENT GROUPS ABLATION Chair: Chair: Morgan J. M. - Southampton, GBR Kautzner J. - Praha, CZE Theodorakis G. - Athens, GRC Santini M. - Roma, ITA • atients with Bundle Branch Block P • emote Magnetic Catheter Navigation: Is It the «Gold Standard»? R Moya A. - Barcelona, ESP Ernst S. - Hamburg, DEU • yncope in Athletes S • ethods, Efficacy, and Safety of Robotic Catheter Ablation for M Flevari P. - Halandri, GRC Atrial Fibrillation • yncope in the Elderly: Particularities S Pisapia A. - Marseille, FRA Kenny R. A. - Dublin, IRL • hree-Dimensional Rotational Angiography: A New Online T • yncope Unit: A New Necessity? S Imaging Tool Brignole M. - Lavagna, ITA Noelker G. - Bad Oeynhausen, DEU • atheter Ablation of Atrial Fibrillation Using a New Non- C Fluoroscopic Sensor-Guided 3D Navigation Tool Hindricks G. - Leipzig, DEU Friday June 15 / 14:00 - 15:30 Friday June 15 / 16:00 - 17:30 MANAGEMENT OF PATIENTS WITH ARRHYTHMIAS IN WOMEN: STATE OF THE DEFIBRILLATOR SHOCKS: STATE-OF-THE ART EVIDENCE Chair: Chair: Boriani G. - Bologna, ITA Borggrefe M. - Mannheim, DEU Morgan J. M. - Southampton, GBR Heidbüchel H. - Leuven, BEL • ncidence, Predictors and Impact on Mortality I • anaging Arrhythmias in Pregnancy: What’s in the Guidelines? M van Rees H. - Den Haag, NLD Blomstrom-Lundqvist C. - Uppsula, SWE • CD Configuration and Programming to Optimise Shock I • ender Differences in Atrial Fibrillation G Treatment Mont L. - Barcelona, ESP Katz A. - Ashkelon, ISR • utcomes in Women Undergoing Electrophysiological O • esults of Catheter Ablation in Patients with Shocks R Procedures Arenal Maiz A. - Madrid, ESP Santangeli P. - Austin, USA • ow to Manage Patient Anxiety H • mplantable Cardioverter Defibrillators in Women I Ladwig K. H. - München, DEU Zupan I. - Ljubljana, SVN 16 www.cardiostim.com
  • 17. Cardiostim 2012 European Heart Rhythm Association (EHRA) Program Friday June 15 / 16:00 - 17:30 Saturday June 16 / 09:00 - 10:30 NEW ENERGIES AND TECHNOLOGIES TO TREAT CERTIFICATION: FIGHTING AGAINST INEQUALITY ATRIAL FIBRILLATION IN HEALTH CARE ACROSS BORDERS Chair: Chair: Davies W. - London, GBR Auricchio A. - Lugano, CHE Kuck K. H. - Hamburg, DEU Nielsen J. C. - Aarhus, DNK • apping and Pulmonary Vein Isolation Using the PVAC M • Powerful Tool for Improvement in Health Care A Duytschaever M. - Brugges, BEL Zeppenfeld K. - Leiden, NLD • ryoballoon Pulmonary Vein Isolation Guided by Real-Time PV C • odels to Be Listened: UK M Potential Recording Linker N. J. - Middlesbrough, GBR Hoffmann E. - Munich, DEU • ertification of Allied Professionals C • ow-Level Vagosympathetic Nerve Stimulation: A New Target L Nolan P. - Galway, IRL for Atrial Fibrillation Suppression? • ertification in Europe: Differences with and Lessons from USA C Jackman W. M. - Oklahoma City, USA Arribas Ynsaurriaga F. - Madrid, ESP • inimally Invasive Surgical Techniques: For Which Patients? M La Meir M. - Maastricht, NLD Saturday June 16 / 09:00 - 10:30 DEBATES AND CONTROVERSIES IN THE ANTITHROMBOTIC MANAGEMENT OF ATRIAL FIBRILLATION Chair: Savelieva I. - London, GBR • ow Risk Patients with Atrial Fibrillation Can Be Treated with L No Antithrombotic Therapy: FOR Fauchier L. - Tours, FRA • ow Risk Patients with Atrial Fibrillation Can Be Treated with L No Antithrombotic Therapy: AGAINST Rasmussen L. H. - Aalborg, DNK • ntiplatelet Therapy Should Be Added to Anticoagulant Therapy A in Patients with Atrial Fibrillation and Vascular Disease: FOR Rubboli A. - Bologna, ITA • ntiplatelet Therapy Should Be Added to Anticoagulant Therapy A in Patients with Atrial Fibrillation and Vascular Disease: AGAINST Marin F. - Murcia, ESP www.cardiostim.com 17
  • 18. Advance program European Heart Rhythm Association (EHRA) Program Saturday June 16 / 11:00 - 12:30 Saturday June 16 / 11:00 - 12:30 ANTIARRHYTHMIC DRUGS FOR ATRIAL NURSE-LED INTERVENTIONS FOR PATIENTS FIBRILLATION WITH ARRHYTHMIAS Chair: Chair: Capucci A. - Ancona, ITA Linker N. J. - Middlesbrough, GBR van Gelder I. C. - Groningen, NLD Zeppenfeld K. - Leiden, NLD • asics of Ion Channel Antiarrhythmic Drugs for Prevention of B • OPE-ICD Trial: Comprehensive Rehabilitation for Patients C Atrial Fibrillation with Implantable Defibrillators Dobrev D. - Heidelberg, DEU Kikkenborg Berg S. - Copenhagen, DNK • asics of Upstream Therapies for Prevention of Atrial Fibrillation B • educing Psychological Distress for Patients with Implantable R Goette A. - Magdeburg, DEU Defibrillators • on Channel Antiarrhythmic Drugs for Prevention of Atrial Fibrillation I Dunbar S. - Atlanta, USA Crijns H. J. - Maastricht, NLD • mplementing a Nurse-Led Atrial Fibrillation Clinic I • pstream Therapies for Prevention of Atrial Fibrillation U Hendriks J. M. L. - Maastricht, NLD Savelieva I. - London, GBR • alpitations: Effectiveness of A Nurse-Led Clinic P Smallwood A. - Wolverhampton, GBR In parallel with the scientific sessions, EHRA will hold a General Assembly to update members and attendees on its activities, while meetings of various committees and working groups will take place throughout the Congress. EHRA Membership 2012, DISCOVER YOUR BENEFITS ON OUR WEB SITE • pecial registration fee for EHRA educational courses S • ree registration for the EHRA Webinars (e-learning) F • 5% discount on EHRA Certification Examinations 1 • 10% off all cardiology publications from Oxford University Press (OUP). • Reduced fee for the EP Europace journal • xclusive access to EHRA Training Fellowships and a selection of EHRA Educational Content Online E • utomatic ESC membership and benefits: Free ESC Pocket Guidelines at the ESC Congress, A Discount prices on the ESC Educational Products, Special subscription prices on ESC Journals (including EHJ), Receive ESC congresses related information, Receive ESC Educational Programme information, A personal European Membership Card (currently for members of some National Cardiac Societies only) • Receiving the EHRA E-newsletter • Voting rights More at WWW.ESCARDIO.ORG/EHRA 18 www.cardiostim.com
  • 19. Cardiostim 2012 Basic Electrophysiology Chairman: D. Zipes - Indianapolis, USA Scientific Committee Ackerman M. - Rochester, USA Nattel S. - Montreal, CAN Anderson M.E. - Iowa City, USA Priori S. G. - Pavia, ITA Antzelevitch C. - Utica, USA Roden D.M. - Nashville, USA Borggrefe M. - Mannheim, DEU Rosen M. R. - New York, USA Boyden P. - New York, USA Rosenbaum D.S. - Cleveland, USA Chen P.S. - Indianapolis, USA Rudy Y. - St Louis, USA Delmar M. - New York, USA Saffitz J. - Boston, USA Ideker R. - Birmingham, USA Schwartz P. J. - Pavia, ITA Jalife J. - Ann Arbor, USA Tomaselli G. - Baltimore, USA Kleber A. - Bern, CHE Trayanova N. A. - Baltimore, USA London B. - Pittsburgh, USA Weiss J. - Los Angeles, USA Mazgalev T.N. - Cleveland, USA Wilde A. M. - Amsterdam Zuidoost, NLD Moss A.J. - Rochester, USA TRANSLATIONAL DISCOVERIES IN CARDIAC ELECTROPHYSIOLOGY: From Cell to Bedside Wednesday June 13 / 09:00 - 10:30 Wednesday June 13 / 11:00 - 12:30 CARDIAC STEM CELLS AND GENE THERAPY NEW IMAGING TECHNIQUES Chair: Chair: Cohen I. - Stony Brook, USA Kalman J. - Melbourne, AUS Fast V. - Birmingham, USA Mazgalev T.N. - Cleveland, USA • aking Hearts Regenerate M • lectrocardiographic Imaging to Understand Arrhythmia E Pedrazzini T. - Lausanne, CHE Mechanisms • ardiac Differentiation of Human Keratinocytes Derived from C Rudy Y. - St. Louis, USA Plucked Hair Follicles • imulations to Predict Sites of VT Ablation S Binah O. - Haifa, ISR Trayanova N. A. - Baltimore, USA • RI for Risk Prediction of Arrhythmogenic Areas M • nduced Pluripotent Stem Cells from Patients with Inherited I Halperin H. - Baltimore, USA Arrhythmias • hat Are the Clinical Implications? W January C. T. - Madison, USA Borggrefe M. - Mannheim, DEU • hat Are the Clinical Implications? W • eneral Discussion G Rosen M. R. - New York, USA • General Discussion www.cardiostim.com 19
  • 20. Advance program Basic Electrophysiology Wednesday June 13 / 14:00 - 15:30 Thursday June 14 / 09:00 - 10:30 MYOCYTE-FIBROBLAST INTERACTIONS IN CONTRIBUTION OF GENETICS TO NORMAL AND DISEASED MYOCARDIUM UNDERSTANDING MECHANISMS AND RISK Chair: Chair: Kleber A. - Bern, CHE Sanders P. - Adelaide, AUS Vos M. - Utrecht, NLD Lazzara R. - Oklahoma City, USA • yocyte Fibroblast Interaction M • xperimental Models to Explain Inherited Diseases E Kohl P. - London, GBR Antzelevitch C. - Utica, USA • yofibroblasts as Arrhythmia Triggers M • athology to Explain Phenotype P Rohr S. - Bern, CHE Basso C. - Padova, ITA • lectromechanical Consequences of Adult Cardiomyocyte E • ellular Electrophysiology to Explain Clinical Phenotypes C Myofibroblast Interactions Napolitano C. - Pavia, ITA Jalife J. - Ann Arbor, USA • hat Are the Clinical Implications? W • hat Are the Clinical Implications? W Moss A. J. - Rochester, USA Duffy H. - Boston, USA • General Discussion • General Discussion Wednesday June 13 / 16:00 - 17:30 Thursday June 14 / 11:00 - 12:30 CARDIAC ION CHANNELS AND DOES GENETIC TESTING FOR SUDDEN DEATH MACROMOLECULAR COMPLEXES IN HEALTH HELP IN CLINICAL PRACTICE? AND DISEASE Chair: Chair: Tseng G. N. - Richmond, USA Fishman G. - New York, USA Priori S. G. - Pavia, ITA Fedorov V. - Columbus, USA • Syndrome • acromolecular Complexes and the Control of Cardiac Ion M Schwartz P. J. - Pavia, ITA Channel Expression and Distribution • rugada Syndrome and CPVT B Abriel H. - Bern, CHE Brugada P. - Aalst, BEL • ntercalated Disc as a Macromolecular Complex Niche and Its I • Hypertrophic Cardiomyopathy Role in ARVC Maron B. - Minneapolis, USA Delmar M. - New York, USA • ut of Hospital Cardiac Arrest O • AGUK Proteins Are Important in Ion Channel Diseases M Chugh S. S. - Los Angeles, USA Hatem S. - Paris, FRA • hat Are the Clinical Implications? W • hat Are the Clinical Implications? W Viskin S. - Tel Aviv, ISR Coronel R. - Amsterdam, NLD • General Discussion 20 www.cardiostim.com
  • 21. Cardiostim 2012 Basic Electrophysiology Thursday June 14 / 14:00 - 15:30 Friday June 15 / 09:00 - 10:30 THE INTERCALATED DISC AND ROLE OF CaMKII IN ARRHYTHMIAS ARRHYTHMOGENIC CARDIOMYOPATHY Chair: Chair: Maier L. - Goettingen, DEU Poelzing S. - Salt Lake City, USA Gilmour R. - Ithaca, USA Ehrlich J. - Frankfurt, DEU • aMKII Regulation of Ion Channels C • ased on Science, What Is the Best Name for Arrhythmogenic B Pitt G. - Durham, USA Right Ventricular Cardiomyopathy? • aMKII Regulation of RyR Receptors and Ca Cycling C McKenna W. - London, GBR Wehrens X. H. - Houston, USA • ell-Cell Communication in ARVC C • ole of CaMKII in Cardiac Arrhythmias R Greene K. - Chicago, USA Mohler P. J. - Columbus, USA • rrhythmia Mechanisms and Therapy A • aMKII as a Potential Antiarrhythmic Target C Calkins H. - Baltimore, USA Maier L. - Goettingen, DEU • hat Is Needed for a Cure? W • hat Are the Clinical Implications? W Thiene G. - Padova, ITA Rosenbaum D. S. - Cleveland, USA • hat Are the Clinical Implications? W Marcus F. - Tucson, USA Thursday June 14 / 16:00 - 17:30 Friday June 15 / 11:00 - 12:30 UNDERSTANDING ATRIAL FIBRILLATION ROLE OF THE AUTONOMIC NERVOUS SYSTEM Chair: IN ARRHYTHMOGENESIS Hocini M. - Bordeaux, FRA Chair: Probst V. - Nantes, FRA Yamada K. - St. Louis, USA Franz M. - Washington, USA • otassium Channel Remodeling P Nattel S. - Montreal, CAN • ympathetic-Vagal Interactions in Conscious Dogs S • emodeling of Calcium Handling R Lin S- F. - Indianapolis, USA Dobrev D. - Heidelberg, DEU • agal Modulation of Atrial Arrhythmias V • Structural Remodeling Po S. - Oklahoma City, USA Allessie M. - Maastricht, NLD • agal Modulation of Inflammation V • hat Are the Clinical Implications? W Sabbah H. - Detroit, USA Natale A. - Austin, USA • hat Are the Clinical Implications? W • General Discussion Goldberger J. - Chicago, USA • General discussion www.cardiostim.com 21
  • 22. Advance program Basic Electrophysiology Friday June 15 / 14:00 - 15:30 Philippe Coumel Session SMALL CONDUCTANCE CALCIUM-ACTIVATED Introduction: from Mechanism to Process. POTASSIUM CHANNELS (SK) AND CARDIAC Paradigm Shift? ARRHYTHMIAS Wednesday June 13 / 09:00 - 10:30 Chair: ATRIAL FIBRILLATION: DEALING WITH Lakatta E. - Baltimore, USA Opthof T. - Utrecht, NLD COMPLEXITY Chair: • hat Are SK Channels? W Guiraudon G.M.- London, CAN Chiamvimonvat N. - Chicago, USA Klein G. J. - London, CAN • K Channels and Ventricular Arrhythmias in Heart Failure S • ntrinsic Autonomic Cardiac Nervous System: New Physiology I Chen P- S. - Indianapolis, USA or Deregulation? Has Neuroablation Predictable Long-Term • K Channels Modulate Cardiogenesis S Effects? Liebau S. - Ulm, DEU Cardinal R. - Montreal, CAN • K Channels and Genetic Basis of Atrial Fibrillation S • nderstanding the Complexity of the Substrate of Human AF U Ellinor P. - Boston, USA Allessie M. - Maastricht, NLD • hat Are the Clinical Implications? W • hen Complexity Beats Ablation? Alternative Interventions to W Myerburg R. J. - Miami, USA Restore Chronotropic Function, and Stroke Prevention Guiraudon G.M. - London, CAN Friday June 15 / 16:00 - 17:30 ROLE OF miRNAs IN ARRHYTHMIA SYNDROMES Chair: Grunnet M. - Copenhagen, DNK Boyden P. - New York, USA • hy All the Interest in miRNAs? W Pinto Y. - Amsterdam, NLD • Hypertrophic Cardiomyopathy Ackerman M. - Rochester, USA • ong QT Syndrome L Wilde A. M. - Amsterdam Zuidoost, NLD • Dilated Cardiomyopathy Engelhardt S. - Munich, DEU • hat Are the Clinical Implications? W Roden D. M. - Nashville, USA 22 www.cardiostim.com
  • 23. Cardiostim 2012 Complex Electrophysiology and Ablation Techniques Course Directors: Scheinman M. - San Fransciso, USA O’Neill M. - London, GBR Probst V. - Nantes, FRA Sacher F. - Bordeaux, FRA Wednesday June 13 / 11:00 - 12:30 Wednesday June 13 / 16:00 - 17:30 ATRIAL FIBRILLATION ABLATION I ATRIAL FIBRILLATION ABLATION III • echanisms of Atrial Fibrillation. Implication for Ablation M • ryo Balloon Ablation of AF C Strategies Ellenbogen K. - Richmond, USA Nattel S. - Montreal, CAN • atients Selection for AF Ablation P • eal Time Mapping to Guide Atrial Fibrillation Ablation R O’Neill M. - London, GBR Narayan S. - San Diego, USA • ow to Identify Targets and End-Points for Atrial Fibrillation H • MR Imaging:” Does It Have a Role in Atrial Fibrillation “ Ablation? Ablation? Asirvatham S. J. - Rochester, USA Marrouche N. F. - Salt Lake City, USA • ong-Term Outcome for Atrial Fibrillation Ablation L • trial Fibrillation Ablation for Patients with Long Standing A Knecht S. - Brussels, BEL Persistent Atrial Fibrillation Sanders P. - Adelaide, AUS Wednesday June 13 / 14:00 - 15:30 ATRIAL FIBRILLATION ABLATION II • ewer Left Atrial Appendage Occlusion and Ligation Devices N for Stroke Prevention: Should They Be Part of an Atrial Fibrillation Procedure? Lee R. J. - San Francisco, USA • picardial Ablation of Atrial Fibrillation E Michaud G. F. - Boston, USA • atheter Ablation of Atrial Fibrillation Using a Non- C Fluoroscopic Sensor Navigation Device Hindricks G. - Leipzig, DEU • ontact Monitoring and New Ablation Toys C Wright M. - London, USA www.cardiostim.com 23
  • 24. Advance program Complex Electrophysiology and Ablation Techniques Thursday June 14 / 09:00 - 10:30 Thursday June 14 / 14:00 - 15:30 ATRIAL FLUTTER ABLATION PAROXYSMAL SUPRAVENTRICULAR • nusual forms (Double Loop, Lower Loop and Intra-Isthmus U TACHYCARDIA ABLATION II Reentry) • blation of the Patient with Atrio-Fascicular Pathways A Mounsey J. P. - Chapel Hill, USA Jackman W. M. - Oklahoma City, USA • pproach to the Ablation of Post Atrial Fibrillation Induced Left A • blation of Atrial Tachycardia/Accessory Pathways from the A Atrial Flutter Aortic Sinus Knecht S. - Brussels, BEL Kuck K. H. - Hamburg, DEU • iagnoses and Ablation of Right Sided Flutter D • ow to Best Diagnose SVT Mechanisms? H Yagi T. - Sendai, JPN Callans D. - Philadelphia, USA • resentation of Complex Cases (SVT) P Scheinman M. - San Fransciso, USA Thursday June 14 / 11:00 - 12:30 Thursday June 14 / 16:00 - 17:30 PAROXYSMAL SUPRAVENTRICULAR Interactive session TACHYCARDIA ABLATION I • nteractive session I • echanisms and Results of Ablative Therapy for Patients with M Badhwar N. - San Francisco, USA Focal Junctional Tachycardia Kalman J. M. - Parkville, AUS Cheng J. - Houston, USA Kuck K. H. - Hamburg, DEU Callans D. - Philadelphia, USA • blation of Complex ANVRT Circuits A Badhwar N. - San Francisco, USA • iagnoses, Therapy and Results of Ablative Therapy for D Patients with Manifest or Concealed Nodo-Fascicular (Ventricular) Pathways Badhwar N. - San Francisco, USA • ocalization and Ablation of Atrial Tachycardias L Kalman J. M. - Parkville, AUS 24 www.cardiostim.com
  • 25. Cardiostim 2012 Complex Electrophysiology and Ablation Techniques Friday June 15 / 09:00 - 10:30 Friday June 15 / 14:00 - 15:30 VENTRICULAR TACHYCARDIA ABLATION I VENTRICULAR TACHYCARDIA ABLATION III - • ole of Identifying and Ablating Late Potentials R Debates Jaïs P. - Bordeaux, FRA • atients with 1st Appropriate ICD Shock Should be Treated P • ecognition and Ablation of Intraseptal VT R with Ablation Bogun F. - Ann Arbor, USA PRO: Sapp J. - Halifax, CAN • oes Cardiac MRI Identify the Critical VT Isthmus? D CON: TBD Dickfeld T. - Baltimore, USA • blation of AF: First Line Therapy in Electrical Storms A • he Role of Endocardial Unipolar Recordings for VT Ablation T PRO: Boyle N. - Los Angeles, USA Callans D. - Philadelphia, USA CON: Coromilas J. - New York, USA Friday June 15 / 11:00 - 12:30 Friday June 15 / 16:00 - 17:30 VENTRICULAR TACHYCARDIA ABLATION II VENTRICULAR TACHYCARDIA ABLATION IV • atheter Ablation of Fascicular Tachycardia in Practice C • atheter Ablation of Patients with Arrhythmogenic Right C Nogami A. - Kanagawa, JPN Ventricular Dysplasia (ARVD) • atheter Ablation of VT from Papillary Muscles C Reddy V. Y. - Boston, USA Kay N. - Birmingham, USA • atheter Ablation of Patients with VT and Systemic Disease C • F Ablation in Post MI Patients V (Sarcoid/Amyloid/Iron Overload/Myotonic Dystrophy) Snumowski L. - Warsaw, POL Arruda M. - Case Western, USA • ong-Term Outcome after VF Ablation L • blation of the Patient with Ischemic VT A Hocini M. - Bordeaux, FRA Soejima K. - Kawasaki, JPN • ipolar Voltage Map vs. MR for Detection of Myocardial Scar B Gerstenfeld E. P. - Philadelphia, USA www.cardiostim.com 25
  • 26. Advance program Complex Electrophysiology and Ablation Techniques Cases Discussion in Electrophysiology Organized by Klein G.J. - London, CAN Sacher F. - Bordeaux-Pessac, FRA O’Neill M. - London, GBR Speakers are invited to present 1 or 2 cases they found instructive or challenging. The problem might be diagnostic or related to ablation complexity. Speakers should be prepared to be interrupted and participate in dialogue during the presentation and consider this in the length of their presentation. Saturday June 16 / 9:00 - 10:30 Saturday June 16 / 11:00 - 12:30 THE CHALLENGING CASE - Part I THE CHALLENGING CASE - Part II Chair: Chair: Klein G. J. - London, CAN Klein G. J. - London, CAN Callans D. - Philadelphia, USA Callans D. - Philadelphia, USA O’Neill M. - London, GBR O’Neill M. - London, GBR Skanes A. - London, CAN Skanes A. - London, CAN State-of-the-Art in the Brugada Syndrome Organized by Sacher F. - Bordeaux-Pessac, FRA Friday June 15 / 09:00 - 10:30 Friday June 15 / 11:00 - 12:30 THERAPEUTIC OPTIONS IN BRUGADA UNSOLVED ISSUES IN BRUGADA SYNDROME SYNDROME Chair: Wilde A. M. - Amsterdam Zuidoost, NLD • isk Stratification in Brugada Syndrome R Antzelevitch C. - Utica, USA Delise P. - Trevise, ITA • utcome after ICD Implantation O • CN5A: Which Role in Brugada Syndrome? S Sacher F. - Bordeaux-Pessac, FRA Probst V. - Nantes, FRA • F Ablation in Brugada Syndrome V • rugada Syndrome Mechanism: Depolarization/Repolarization B Nademanee K. - Los Angeles, USA or Different Entities with a Same ECG Pattern Postema P.G. - Amsterdam, NLD • alue of Electrophysiological Study for Risk Stratification: The V PRELUDE Study Priori S. G. - Pavia, ITA 26 www.cardiostim.com
  • 27. Cardiostim 2012 Complex Electrophysiology and Ablation Techniques Novel Approaches to Apply Mechanistic Insights to Complex Human Arrhythmias Organized by E. Pruvot - Lausanne, CHE S. Narayan - San Diego, USA Goals: To discuss the implementation and practical application of principles and insights from basic science to understand and treat human arrhythmias. Because the detailed mapping and tissue analyses for in silico, in vitro and in vivo animal models often cannot be applied in patients, this session will also discuss technical innovations that have enabled successful translational patient studies. Thursday June 14 / 14:00 - 15:30 Thursday June 14 / 16:00 - 17:30 MECHANISTIC APPROACHES TO COMPLEX MECHANISTICALLY-GUIDED THERAPIES FOR ARRHYTHMIAS - PART I: REPOLARIZATION HUMAN CARDIAC FIBRILLATION - PART II - ALTERNANS – TRANSLATING FUNDAMENTAL ATRIAL ARRHYTHMIAS OBSERVATIONS TO CLINICAL PRACTICE FOR Chair: ATRIAL AND VENTRICULAR ARRHYTHMIAS Berenfeld O. - Ann Arbor, USA Chair: Pruvot E. - Lausanne, CHE • asic Science of Atrial Fibrillatory Sources: The Role of Rotors B Narayan S. - San Diego, USA vs Multiple Wavelets Jalife J. - Ann Arbor, USA • rom Pulsus to Pulseless: The Saga of Cardiac Repolarization F • ocalized Rotors and Focal Beats in Human Atrial Fibrillation L Alternans Narayan S. - San Diego, USA Rosenbaum D. S. - Cleveland, USA • linical Application of Noninvasive Electrocardiographic C • ntermittent Atrial Tachycardia Promotes Repolarization I Imaging (ECGI) Alternans and Susceptibility to AF in a Free-Behaving Sheep Cuculich P. - St Louis, USA Model • lectrogram Correlates of Localized Sources During AF E Pruvot E. - Lausanne, CHE Mansour M. - Boston, USA • trial Repolarization Alternans as a Dynamic Substrate A • ole of Imaging and Ablating Structural Obstacles to Treat R Promoting Wavebreaks in Human Paroxysmal and Persistent Human AF AF Marrouche N. F. - Salt Lake City, USA Narayan S. - San Diego, USA • ERCA2A Overexpression as a Molecular Intervention to S Suppress Repolarization Alternans and Susceptibility of Cardiac Fibrillation Cutler M. - Cleveland, USA • ntracardiac Repolarization Alternans/Variability Predicts I Imminent Ventricular Tachyarrhythmias in ICD Recipients Swerdlow C. D. - Los Angeles, USA www.cardiostim.com 27
  • 28. Advance program Complex Electrophysiology and Ablation Techniques Friday June 15 / 09:00 - 10:30 Computer Modelling MECHANISTICALLY-GUIDED APPROACHES TO Organized by Maxime Sermasant - Sophia Antipolis, FRA from INRIA HUMAN CARDIAC FIBRILLATION - PART III - (Institut National de Recherche en Informatique et Automatique) VENTRICULAR ARRHYTHMIAS Chair: Shivkumar K. - San Diego, USA Thursday June 14 / 11:00 - 12:30 • rigger Mechanisms for Human Ventricular Fibrillation T COMPUTATIONAL ELECTROPHYSIOLOGY: Knecht S. - Bordeaux, FRA NOVEL TOOLS TO IMPROVE CLINICAL • ecent Developments in Defibrillation and in Understanding R Ventricular Fibrillation UNDERSTANDING Ideker R. - Birmingham, USA Chair: Panfilov A. V. - Gent, BEL • hat Is the Optimal Mapping Approach to Guide Ablation of W Rhode K. - London, GBR Human Ventricular Tachyarrhythmias? Shivkumar K. - Los Angeles, USA • lectrotonic Modulation of Cardiac Repolarization in Health E • ignal Processing Approaches to Guide Complex Ablation in S and Disease: Insights from a Combined Computational and the Atria and Ventricles Experimental Study Chen S.A. - Taipei, TWN Bernus O. - Bordeaux-Pessac, FRA • ignal Processing Insights into the Mechanisms of Human S • lectro-Mechanical Interaction – Is This Something the E Ventricular Arrhythmias Clinical Electrophysiologist Has to Care about or Is This only of Krummen D.E. - San Diego, USA Interest to the Cellular Researcher? Bijnens B. - Barcelona, ESP • lectrical and Structural Characteristics of Border Zone in E Infarcted Swine: Insights from 3D MR Image-Based Computer Models, Histopathology and EP Data Pop M. - Toronto, CAN • ardiac Radiofrequency Ablation Planning from Personalized C Biophysical Models Delingette H. - Sophia-Antipolis, FRA 28 www.cardiostim.com
  • 29. Cardiostim 2012 Treatments of Atrial Fibrillation Advances and Controversies in Atrial Fibrillation (ACAF) Chairman: Naccarelli G. V. - Hershey, USA Blanc J.J. - Brest, FRA Lévy S. - Marseille, FRA Unrestricted Educational Support: sanofi aventis Thursday June 14 / 09:00 - 10:30 Thursday June 14 / 14:00 - 15:30 ATRIAL FIBRILLATION I ATRIAL FIBRILLATION III Chair: Chair: Naccarelli G. V. - Hershey, USA Santini M. - Rome, ITA Boriani G. - Bologna, ITA Breithardt G. - Münster, DEU • arly Attempts at Rhythm Control Slows Progression of AF E • ovel Anticoagulants: Where Are We in 2012? N Crijns H. J. - Maastricht, NLD Naccarelli G. V. - Hershey, USA • as Basic Science Helped Us Develop Better Pharmacologic H • an Newer Anticoagulants Be Used Safely for Cardioversion C and Ablative Therapies for AF? of AF Patients? Allessie M. - Maastricht, NLD Aliot E. - Nancy, FRA • pstream Therapy of AF – Is It All over but the Shouting? U • ntiarrhythmic/Anticoagulant Drug Interactions: What Do We A Dorian P. - Toronto, CAN Know? Tamargo J. - Madrid, ESP Thursday June 14 / 11:00 - 12:30 Thursday June 14 / 16:00 - 17:30 ATRIAL FIBRILLATION II ATRIAL FIBRILLATION IV Chair: Chair: van Gelder I. C. - Groningen, NLD Lévy S. - Marseille, FRA Capucci A. - Ancona, ITA Vardas P. E. - Heraklion, GRC • ronedarone in 2012: What is New? D • symptomatic AF: Prognostic Implications A Le Heuzey J. Y. - Paris , FRA Blanc J. J. - Brest, FRA • ALLAS: Why Was It Performed? Where Are We? P • s Catheter Ablation of AF Prothrombotic or Antithrombotic? I Hohnloser S. - Frankfurt, DEU Packer D. L. - Rochester, USA • ronedarone and Ranolazine: Is a Combination Drug a Good D • ole of Novel Anticoagulants During AF Ablation Procedures? R Idea ? Cappato R. - San Donato Milanese (MI), ITA Antzelevitch C. - Utica, USA www.cardiostim.com 29