2. LIST OF CONTENTS
Introduction
Signals for Degradation
Site of Degradation
The Ubiquitin- Proteosome pathway
Lysosomal Proteolysis
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4. CONTINUED …
In Lysosomes and cytosol
Signals for degradation
• Protein function
• Proteins altered by oxidation
• Tagged by ubiquitin
• N terminal
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8. MCQS
Many rapidly degraded proteins function as
regulatory molecules, such as ______
a) Transcriptions factors b) histones c)
silencers d) proteases
The major pathway of selective protein degradation
in eukaryotic cells uses_____as marker
a) Ubiquitin b) protease c) beta subunit
d ) lysosome
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