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New Strategies for the
    Prevention of
 Respiratory Diseases

 Alexandru Corlateanu, MD, PhD
     MEDICAL CLINIC No. 2,
    “N.TESTEMITANU” SUMP
POPULATION MORTALITY BY THE MAIN
             CAUSES OF DEATH




World Health Organization. Top Ten Causes of Death. Fact Sheet.
www.who.int/mediacentre/factsheets/fs310_2008.pdf Date last updated: November 2008.




                                                                                      2
COPD – a public health problem
        •     On a global scale – 210 million of patients and 3 million of deaths
              annually (5% of global mortality)1
        •     Prevalence is on the rise: the 6th cause of mortality globally in
              1990, roughly – the 3rd cause in 20202
        •     Under-diagnosed and under-treated disease: Great Britain - 2008:
              835000 of COPD diagnosed patients, the real number is estimated
              at over 3 millions3
        •     Significant economic burden – European Union: respiratory
              diseases - 6% of the health budget, 56% of which are allocated for
              COPD4

1.World Health Organization. World Health Report 2004. Statistical Annex - table 2 and 3: 120-131
1.World
2. Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 1997 ; 349(9064): 1498-504.
                                                                                                                            3
3. The NHS Information Centre for Health and Social Care. Quality of outcomes framework 2008/09 – Prevalence. http://www.ic.nhs.uk Date last accessed : July 2010
4. European Respiratory Society. European Lung White Book. Huddersfield, European Respiratory Society Journals Ltd, 2003.
Endogeneous risk factors              Exogeneous risk factors
                            •          Tobacco smoke
• Deficit of α1-antitrypsin •          Industrial dust
• Bronchial                            and fume
  hyperreactivity           •          Home and
• Lungs maldevelopment
                                      environment pollution
                                  •    Infections
                                  •    Low social and
                                       economic status




    GOLD 2011, www.goldcopd.org
      97% of the public health expenses are
  currently used  for treatment, and only 3%
  are invested in the prevention of
  respiratory diseases
      In 2010 COPD incurred EUR 280
  billion as costs for the world economy
European Respiratory Roadmap

 Prevention
 Clinical medicine
 Research
 Education




                        7
Recommendations for prevention
    of respiratory diseases
   Implement the WHO Framework Convention on
    Tobacco Control in Europe
   Implement the Parma Declaration on Air Pollution
    and Climate Change
   Implement the UNO Acts related to the prevention
    of non-transmissible chronic respiratory diseases




                                          8
Recommendations for prevention
    of respiratory diseases

   Promote physical activity and diets
   Develop cost-efficient methods of early
    diagnosis and detection of respiratory diseases




                                       9
Achievements at the national level
• A round-table on the World No Tobacco Day was held for promotion of
the project of the National Tobacco Control Programme for 2011-2016 ,
where there was considered information on “The Tobacco Consumption
Epidemic in the Republic of Moldova and the draft National Action Plan
on Tobacco Control for 2011-2016”, “Tax and Customs Policy in the field
of Tobacco Control”, “Perspectives on Implementation of Agricultural
Alternatives to Tobacco in the Republic of Moldova”

Conference Workshop WHO Framework Convention on Tobacco Control

• Information, education and communication campaigns related to the
healthcare promotion and education for health were organized during
the World Days




                                                                  10
Primary problems at the national
             level
• The project is part of an international study BOLD (Burden of Obstructive
   Lung Diseases), which has already been conducted in many countries (USA,
   Turkey, China, Great Britain, Austria, etc).


• Highlight the risk factors, study the prevalence and clinical and functional
   characteristics in the patients with chronic obstructive lung disease
   (obstructive pulmonary diseases) in order to improve the early diagnosis,
   upgrade the therapeutic methods and draft forecasting criteria for
   implementation of prophylactic activities in the patients with obstructive
   pulmonary diseases.


                                                                                 11
PRIMARY GOALS:


• Assess the age and gender related prevalence of the risk
  factors of COPD compared to other countries
• Assess the prevalence of comorbidities in COPD patients
• Estimate the COPD impact on the quality of life, limited the
  physical activity and respiratory symptoms
• Develop a validated model to forecast the COPD impact
• Based on the data obtained in the study, develop practical
  recommendations on enhancing the COPD diagnosis at
  different stages of health care provision

                                                                 12
Implementation of a national strategy

Primary goals of the national strategy

 Prevent the onset and progression of chronic respiratory
  diseases
 Accurately identify and diagnose the cases
 Ensure the access of the patient to quality healthcare
 Provide self-care information and education to patients
Prevention of onset and progression
                   of respiratory diseases
   Inform the population
   Campaigns for information and promotion of respiratory health
   Anti-smoking social marketing policies and campaigns

   Limit the action of risk factors
   Professional support to quit smoking
   Air quality standards in living and professional environment

Population screening for respiratory diseases
   Identify the population groups at risk
   Questionnaires to asses the clinical symptoms
   Respiratory functional tests
                                                      14
COPD Detection and Diagnosis
   Accurate diagnosis of COPD
   Quality spirometry – establishing the diagnostic and stage
   Clinical assessment: effort tolerance, dyspnea (MRC), arterial blood
    gases, deficit of α-1-Antitripsyn, state of nutrition, etc.
   Anticipatory management of the chronic disease – clinical and
    functional periodical respiratory reassessment by revising the
    therapy based on the stages of severity
   Periodical assessment and reassessment for presence of
    comorbidities (coronary heart diseases, diabetes, depression,
    osteoporosis, etc.)




                                                      15
Education of Patients and Self-care Promotion

    Education and information programmes for the patients related to
    the new respiratory diseases:
•   Control of risk factors
•   Evolutional character– recurrent exacerbations, comorbidites
•   Treatment administration
•   Correct access to healthcare services



•   Compliance of the patient with the prevention and treatment
    actions
•   Make the patient responsible for the chosen lifestyle
•   Active relation – partnership with the medical and social
    professionals and care implied persons
•   Develop the self-care interests and skills
                                                                  16
•
Reality 
• Under-diagnosed
• Under-estimated
• Under-treated
                                                 Hope 
• Conduct the BOLD (Impact of Obstructive Respiratory
  Diseases) study to identify the unapproached needs in the
  chronic respiratory disease management
• Develop the national intersectorial strategy to approach
  the chronic respiratory diseases, particularly, at primary
  medical aid and by an integral approach with other chronic
  diseases
• Active participation in drafting and carrying out the
  European Respiratory RoadMap and the WHO Global
  Strategy against non-transmissible diseases
  (cardiovascular diseases, c ancer, chronic respiratory

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New strategies of Prevention of Respiratory Diseases

  • 1. New Strategies for the Prevention of Respiratory Diseases Alexandru Corlateanu, MD, PhD MEDICAL CLINIC No. 2, “N.TESTEMITANU” SUMP
  • 2. POPULATION MORTALITY BY THE MAIN CAUSES OF DEATH World Health Organization. Top Ten Causes of Death. Fact Sheet. www.who.int/mediacentre/factsheets/fs310_2008.pdf Date last updated: November 2008. 2
  • 3. COPD – a public health problem • On a global scale – 210 million of patients and 3 million of deaths annually (5% of global mortality)1 • Prevalence is on the rise: the 6th cause of mortality globally in 1990, roughly – the 3rd cause in 20202 • Under-diagnosed and under-treated disease: Great Britain - 2008: 835000 of COPD diagnosed patients, the real number is estimated at over 3 millions3 • Significant economic burden – European Union: respiratory diseases - 6% of the health budget, 56% of which are allocated for COPD4 1.World Health Organization. World Health Report 2004. Statistical Annex - table 2 and 3: 120-131 1.World 2. Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 1997 ; 349(9064): 1498-504. 3 3. The NHS Information Centre for Health and Social Care. Quality of outcomes framework 2008/09 – Prevalence. http://www.ic.nhs.uk Date last accessed : July 2010 4. European Respiratory Society. European Lung White Book. Huddersfield, European Respiratory Society Journals Ltd, 2003.
  • 4. Endogeneous risk factors Exogeneous risk factors • Tobacco smoke • Deficit of α1-antitrypsin • Industrial dust • Bronchial and fume hyperreactivity • Home and • Lungs maldevelopment environment pollution • Infections • Low social and economic status GOLD 2011, www.goldcopd.org
  • 5. 97% of the public health expenses are currently used  for treatment, and only 3% are invested in the prevention of respiratory diseases  In 2010 COPD incurred EUR 280 billion as costs for the world economy
  • 6.
  • 7. European Respiratory Roadmap  Prevention  Clinical medicine  Research  Education 7
  • 8. Recommendations for prevention of respiratory diseases  Implement the WHO Framework Convention on Tobacco Control in Europe  Implement the Parma Declaration on Air Pollution and Climate Change  Implement the UNO Acts related to the prevention of non-transmissible chronic respiratory diseases 8
  • 9. Recommendations for prevention of respiratory diseases  Promote physical activity and diets  Develop cost-efficient methods of early diagnosis and detection of respiratory diseases 9
  • 10. Achievements at the national level • A round-table on the World No Tobacco Day was held for promotion of the project of the National Tobacco Control Programme for 2011-2016 , where there was considered information on “The Tobacco Consumption Epidemic in the Republic of Moldova and the draft National Action Plan on Tobacco Control for 2011-2016”, “Tax and Customs Policy in the field of Tobacco Control”, “Perspectives on Implementation of Agricultural Alternatives to Tobacco in the Republic of Moldova” Conference Workshop WHO Framework Convention on Tobacco Control • Information, education and communication campaigns related to the healthcare promotion and education for health were organized during the World Days 10
  • 11. Primary problems at the national level • The project is part of an international study BOLD (Burden of Obstructive Lung Diseases), which has already been conducted in many countries (USA, Turkey, China, Great Britain, Austria, etc). • Highlight the risk factors, study the prevalence and clinical and functional characteristics in the patients with chronic obstructive lung disease (obstructive pulmonary diseases) in order to improve the early diagnosis, upgrade the therapeutic methods and draft forecasting criteria for implementation of prophylactic activities in the patients with obstructive pulmonary diseases. 11
  • 12. PRIMARY GOALS: • Assess the age and gender related prevalence of the risk factors of COPD compared to other countries • Assess the prevalence of comorbidities in COPD patients • Estimate the COPD impact on the quality of life, limited the physical activity and respiratory symptoms • Develop a validated model to forecast the COPD impact • Based on the data obtained in the study, develop practical recommendations on enhancing the COPD diagnosis at different stages of health care provision 12
  • 13. Implementation of a national strategy Primary goals of the national strategy  Prevent the onset and progression of chronic respiratory diseases  Accurately identify and diagnose the cases  Ensure the access of the patient to quality healthcare  Provide self-care information and education to patients
  • 14. Prevention of onset and progression of respiratory diseases  Inform the population  Campaigns for information and promotion of respiratory health  Anti-smoking social marketing policies and campaigns  Limit the action of risk factors  Professional support to quit smoking  Air quality standards in living and professional environment Population screening for respiratory diseases  Identify the population groups at risk  Questionnaires to asses the clinical symptoms  Respiratory functional tests 14
  • 15. COPD Detection and Diagnosis  Accurate diagnosis of COPD  Quality spirometry – establishing the diagnostic and stage  Clinical assessment: effort tolerance, dyspnea (MRC), arterial blood gases, deficit of α-1-Antitripsyn, state of nutrition, etc.  Anticipatory management of the chronic disease – clinical and functional periodical respiratory reassessment by revising the therapy based on the stages of severity  Periodical assessment and reassessment for presence of comorbidities (coronary heart diseases, diabetes, depression, osteoporosis, etc.) 15
  • 16. Education of Patients and Self-care Promotion Education and information programmes for the patients related to the new respiratory diseases: • Control of risk factors • Evolutional character– recurrent exacerbations, comorbidites • Treatment administration • Correct access to healthcare services • Compliance of the patient with the prevention and treatment actions • Make the patient responsible for the chosen lifestyle • Active relation – partnership with the medical and social professionals and care implied persons • Develop the self-care interests and skills 16 •
  • 17. Reality  • Under-diagnosed • Under-estimated • Under-treated Hope  • Conduct the BOLD (Impact of Obstructive Respiratory Diseases) study to identify the unapproached needs in the chronic respiratory disease management • Develop the national intersectorial strategy to approach the chronic respiratory diseases, particularly, at primary medical aid and by an integral approach with other chronic diseases • Active participation in drafting and carrying out the European Respiratory RoadMap and the WHO Global Strategy against non-transmissible diseases (cardiovascular diseases, c ancer, chronic respiratory

Hinweis der Redaktion

  1. OBIECTIVELE SECUNDARE: Compararea impactului prevalenţei BPCO folosind diferite definiţii şi criterii BPCO: the American Thoracic Society, The European Respiratory Society și GOLD Determinarea influenţei factorilor de risc asupra prevalenţei BPCO Determinarea distribuţiei BPCO conform vârstei, sexului şi statutului de fumător. Descrierea principalelor simptome clinice la pacienţii cu BPCO Evaluarea sensibilităţii şi specificităţii simptomelor BPCO, folosind spirometria şi testul bronhodilatator ca standard de aur Caracterizarea managementului clinic a pacienţilor cu BPCO