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Delivering Nutrition through
Orange-Fleshed Sweetpotato:
  The Growing Evidence Base
     Food Nutrition in Eastern & Southern Africa
                                 Nairobi, Kenya
                             10 September 2012
                              Jan Low, CIP-SSA
An estimated 32% of Africa’s
The Problem    children under five years of age
               are vitamin A deficient.
              Vitamin A deficiency can limit
                growth, weaken immunity, cause
                xeropthalmia leading to
                blindness, and increased risk of
                mortality
              VAD is caused by inadequate
              intakes and loss due to illness
              Food-based approaches to
                 combat VAD address one of
                 the major underlying causes
                 but criticized for lack of evidence
Orange-fleshed Sweetpotato:
  A Potential Contribution to the Solution




 Most varieties in SSA white-fleshed: marginal change
 The Challenge: Will OFSP yield as well as the local variety?
                    Will consumers like the taste?
                    What is needed to impact VAD?
                    Will initial adoption be sustained?
Answering these questions
                                took more than a decade…:

                               1st pilot study in Western
                                Kenya (1995-97)
                               Nutrition education
                                component essential
                               Preferences differed
                                --Adults: high dry matter
                                --Children: low dry matter
                              Yellow-fleshed lack sufficient
                              pro-vitamin A, focus on orange
                               Easy to incorporate
                                sweetpotato weaning foods
                                into young child diet &
KARI/CIP/CARE collaboration
funded by ICRW/OMNI/USAID       improve feeding frequency
Efficacy Study Among School Children in
                   South Africa

                   Resisto




Bosbok        Efficacy
              studies
                            1.   Completed in South Africa in 2004
    Potential of OFSP       2.   Modified relative dose response method
    in combating VAD        3.   120 gm. fed to school children for 5 days a
                                 week for 3 months significantly improved
                                 amounts of Vitamin A stored in the liver

          van Jaarsveld et al., AJCN 81, 1080-87, 2005.
AGRICULTURE                    NUTRITION                    MARKETING
                                       Demand Creation
      Introduce new source of               and                  Market Development
        Vitamin A and Energy:           Empowerment              for OFSP Roots and
           Biofortified OFSP              through                Processed Products
                                         Knowledge

   Mechanisms
                                    1. Create awareness of
                                        Vitamin A problem       1. Link to markets to
1. Substitute white with orange                                      earn income
2. Improve agronomic practices      2. Create awareness of
                                        Vitamin A-rich foods    2. Diversify use through
3. Improve storage practices
                                    3. Empower caregivers            development of
                                        to change practices          OFSP products

   Outcomes
                                    1. Knowledge in local
   1. Increased supply of beta-
        carotene & energy                community
                                                                1. Increased household
   2. Sustained yields              2. Increased demand for
                                                                     income for growers
   3. Increased supply in                Vitamin A-rich foods
                                                                2. Sustained OFSP
        off-season                  3. Increased intake
                                                                     cultivation over time
                                         Vitamin A & energy

                                  Increased Serum Retinol Levels
Integrated (agriculture-nutrition-market)
Intervention at Community Level in Mozambique
 Median intake vitamin A almost 8 times higher (24 h recall)
 OFSP contributed 35% vitamin A intake, 6% of energy intake
 15% decline in prevalence of low serum retinol status
  attributable to the intervention
                          Median nutrient intakes yesterday:
                    non-breastfed children (mean 32 months old)
                                           1600
                                                                                   1414
                                           1400
                                                                                          1226
                                           1200
                      Amount of Nutrient




                                                       Intervention (n=465)
                                           1000

                                           800         Control (n=234)

                                           600
                                                        426
                                           400

                                           200
                                                                 56
                                              0

                                                  Vitamin A (μg RAE)          Energy (kcal)
                                                        P-value=0.00               P-value=0.00
                 Low, JW et al., Journal of Nutrition 137: 1320-1327, 2007
Building the Orange Brand:
Radio programs and market advertising to
   increase awareness of Vitamin A rich
foods & increase demand & combat myths
Learned that higher root yielding OFSP has
insufficient vine vigor for drought-prone areas




              CANASUMANA                          RESISTO:
 -- Hardier vines, more drought resistant     -- Has β-Carotene
     --Alternating not agglomerated       --More consistent medium
               storage roots                 root size desired in
                                             commercial market
Sought funding for a major investment to Breed in
Africa for Africa & to improve the “seed” system...




    Breeder Maria Andrade (on       15 new drought-tolerant
   right) focused on vine vigor,      OFSP varieties were
  drought tolerance, and taste…    released in February 2011
      better yield alone is not
              sufficient
Reaching End Users (REU): 2007-2009

Mozambique: 14,400 households
            144 groups




                                Uganda: 10,292 Households
                                        392 Groups




                                                   Wolfgang H PFEIFFER
High adoption rates (>60%) &
     positive
     outcomes on vitamin A intake among

           children and their mothers
                           (intent to treat figures, include non-
     adopters)
Wolfgang H PFEIFFER

                                      (Impact Study led by IFPRI)




              Estimated Average Requirements (EAR): satisfy 50% of needs of age group
Understanding the costs of using the
            integrated approach
 Less intensive (M2) model 30% cheaper to implement
 No significant difference in 2 models on key metrics
 Mozambique (secondary staple):
    Average cost for direct beneficiary:             $86
    Marginal cost for direct beneficiary:            $36
    Marginal cost if indirect beneficiaries included:      $19
 Uganda (staple crop):
    Average cost for direct beneficiary:             $56
    Marginal cost for direct beneficiary:            $22
    Marginal cost if indirect beneficiaries included:      $12
 $15-20 USD for disability life year (DALY) saved
Would linking more explicitly to a health intervention
substantially improve Vitamin A status?
                  0.4
                 0.35
                  0.3
  Change in      0.25
 serum retinol    0.2
                 0.15
                  0.1
                 0.05
                    0
                         Baseline Fat + Deworming OFSP OFSP + Fat + Deworming
                                    Treatment group

      Mean (± SEM) changes in serum retinol after supplementation
     Source: Fasli Jalal et al., Am J Clin Nutr 1998; 68:623-9.
Can linking an agricultural intervention and nutritional
training to existing ante-natal care services in Western
   Kenya provide an incentive to pregnant women to:
  1) increase health service utilization
  2) increase consumption of OFSP
     and other vitamin A rich foods
     by themselves and their
     children than existing
     health services alone?
   3) Will there be a positive impact
      on vitamin A status?
Conclusions

  OFSP root consumption
   can significantly
   contribute to improved
   vitamin A intake & status
  More research needed on impact of other nutrients
  Still much to learn on:
   --effective delivery systems, how to cost-
      effectively reach large numbers of households
      & HIV/AIDS affected households & communities
        (SUN Initiative may provide opportunities)
    --storage, extended shelf life, processed product
    development (new markets; reach urban consumers)
SPHI is a multi-
                                      partner, multi-donor
                                       initiative that seeks
                                          to reduce child
                                        undernutrition and
                                      improve smallholder
                                     incomes in 10 million
                                        African families by
                                         2020 through the
                                      effective production
                                      and expanded use of
                                           sweetpotato.
         16 Target Countries

         SASHA in 8 countries
Other projects in additional 4 Countries

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Jan Low (CIP) - Delivering Nutrition through Orange-Fleshed Sweetpotato: The Growing Evidence Base

  • 1. Delivering Nutrition through Orange-Fleshed Sweetpotato: The Growing Evidence Base Food Nutrition in Eastern & Southern Africa Nairobi, Kenya 10 September 2012 Jan Low, CIP-SSA
  • 2. An estimated 32% of Africa’s The Problem children under five years of age are vitamin A deficient. Vitamin A deficiency can limit growth, weaken immunity, cause xeropthalmia leading to blindness, and increased risk of mortality VAD is caused by inadequate intakes and loss due to illness Food-based approaches to combat VAD address one of the major underlying causes but criticized for lack of evidence
  • 3. Orange-fleshed Sweetpotato: A Potential Contribution to the Solution  Most varieties in SSA white-fleshed: marginal change  The Challenge: Will OFSP yield as well as the local variety? Will consumers like the taste? What is needed to impact VAD? Will initial adoption be sustained?
  • 4. Answering these questions took more than a decade…:  1st pilot study in Western Kenya (1995-97)  Nutrition education component essential  Preferences differed --Adults: high dry matter --Children: low dry matter Yellow-fleshed lack sufficient pro-vitamin A, focus on orange  Easy to incorporate sweetpotato weaning foods into young child diet & KARI/CIP/CARE collaboration funded by ICRW/OMNI/USAID improve feeding frequency
  • 5. Efficacy Study Among School Children in South Africa Resisto Bosbok Efficacy studies 1. Completed in South Africa in 2004 Potential of OFSP 2. Modified relative dose response method in combating VAD 3. 120 gm. fed to school children for 5 days a week for 3 months significantly improved amounts of Vitamin A stored in the liver van Jaarsveld et al., AJCN 81, 1080-87, 2005.
  • 6. AGRICULTURE NUTRITION MARKETING Demand Creation Introduce new source of and Market Development Vitamin A and Energy: Empowerment for OFSP Roots and Biofortified OFSP through Processed Products Knowledge Mechanisms 1. Create awareness of Vitamin A problem 1. Link to markets to 1. Substitute white with orange earn income 2. Improve agronomic practices 2. Create awareness of Vitamin A-rich foods 2. Diversify use through 3. Improve storage practices 3. Empower caregivers development of to change practices OFSP products Outcomes 1. Knowledge in local 1. Increased supply of beta- carotene & energy community 1. Increased household 2. Sustained yields 2. Increased demand for income for growers 3. Increased supply in Vitamin A-rich foods 2. Sustained OFSP off-season 3. Increased intake cultivation over time Vitamin A & energy Increased Serum Retinol Levels
  • 7. Integrated (agriculture-nutrition-market) Intervention at Community Level in Mozambique  Median intake vitamin A almost 8 times higher (24 h recall)  OFSP contributed 35% vitamin A intake, 6% of energy intake  15% decline in prevalence of low serum retinol status attributable to the intervention Median nutrient intakes yesterday: non-breastfed children (mean 32 months old) 1600 1414 1400 1226 1200 Amount of Nutrient Intervention (n=465) 1000 800 Control (n=234) 600 426 400 200 56 0 Vitamin A (μg RAE) Energy (kcal) P-value=0.00 P-value=0.00 Low, JW et al., Journal of Nutrition 137: 1320-1327, 2007
  • 8. Building the Orange Brand: Radio programs and market advertising to increase awareness of Vitamin A rich foods & increase demand & combat myths
  • 9. Learned that higher root yielding OFSP has insufficient vine vigor for drought-prone areas CANASUMANA RESISTO: -- Hardier vines, more drought resistant -- Has β-Carotene --Alternating not agglomerated --More consistent medium storage roots root size desired in commercial market
  • 10. Sought funding for a major investment to Breed in Africa for Africa & to improve the “seed” system... Breeder Maria Andrade (on 15 new drought-tolerant right) focused on vine vigor, OFSP varieties were drought tolerance, and taste… released in February 2011 better yield alone is not sufficient
  • 11. Reaching End Users (REU): 2007-2009 Mozambique: 14,400 households 144 groups Uganda: 10,292 Households 392 Groups Wolfgang H PFEIFFER
  • 12. High adoption rates (>60%) & positive outcomes on vitamin A intake among children and their mothers (intent to treat figures, include non- adopters) Wolfgang H PFEIFFER (Impact Study led by IFPRI) Estimated Average Requirements (EAR): satisfy 50% of needs of age group
  • 13. Understanding the costs of using the integrated approach  Less intensive (M2) model 30% cheaper to implement  No significant difference in 2 models on key metrics  Mozambique (secondary staple):  Average cost for direct beneficiary: $86  Marginal cost for direct beneficiary: $36  Marginal cost if indirect beneficiaries included: $19  Uganda (staple crop):  Average cost for direct beneficiary: $56  Marginal cost for direct beneficiary: $22  Marginal cost if indirect beneficiaries included: $12  $15-20 USD for disability life year (DALY) saved
  • 14. Would linking more explicitly to a health intervention substantially improve Vitamin A status? 0.4 0.35 0.3 Change in 0.25 serum retinol 0.2 0.15 0.1 0.05 0 Baseline Fat + Deworming OFSP OFSP + Fat + Deworming Treatment group Mean (± SEM) changes in serum retinol after supplementation Source: Fasli Jalal et al., Am J Clin Nutr 1998; 68:623-9.
  • 15. Can linking an agricultural intervention and nutritional training to existing ante-natal care services in Western Kenya provide an incentive to pregnant women to: 1) increase health service utilization 2) increase consumption of OFSP and other vitamin A rich foods by themselves and their children than existing health services alone? 3) Will there be a positive impact on vitamin A status?
  • 16. Conclusions  OFSP root consumption can significantly contribute to improved vitamin A intake & status  More research needed on impact of other nutrients  Still much to learn on: --effective delivery systems, how to cost- effectively reach large numbers of households & HIV/AIDS affected households & communities (SUN Initiative may provide opportunities) --storage, extended shelf life, processed product development (new markets; reach urban consumers)
  • 17. SPHI is a multi- partner, multi-donor initiative that seeks to reduce child undernutrition and improve smallholder incomes in 10 million African families by 2020 through the effective production and expanded use of sweetpotato. 16 Target Countries SASHA in 8 countries Other projects in additional 4 Countries