Implementing A Network Of Virology And Entomology Laboratories For A OH Approach Kathleen VICTOIR
1. MediLabSecure: Implementing a
network of virology and entomology
laboratories for a One Health approach
of vector-borne and respiratory viruses
in the Mediterranean and Black Sea
regions
VICTOIR Kathleen on behalf of the MediLabSecure
Network
GRF One Health Summit 2015, Davos, 5-7 October 2015
2. Some points for a better surveillance of vector borne
infectious diseases:
•Need for more efficient integrated disease surveillance
(lab, epi, multidisciplinar)
•Accessible integrated databases with information
exchange between all concerned parties
•Need for cross-border collaboration
•Regular evaluation of surveillance system
•Outbreak preparation and risk assessment
Negev et al. 2015 Int.J.Environ. Res. Public Health
4. General objectives
To increase, through capacity building, the health security in the
Mediterranean Area, South-East European and Black Sea region by
enhancing and strengthening the preparedness to common health
viral emergencies and biosafety management at national and
regional levels by the creation of a network of laboratories for a
better surveillance of infectious diseases in the region .
• 2014-2017 (48 months)
• European Union DEVCO / EuropeAid
5. Organisation
Coordination, communication and dissemination
Animal
Virology
Human
Virology
Public
Health
Medical
Entomology
Steering Team
Advisory Board (external)
MediLabSecure Member Laboratories and units/ Fpoints in MoH - CoE
6. Specific objectives
• Create a framework for collaboration to improve surveillance and
monitoring of emerging vector-borne viral diseases (arboviruses)
and emerging respiratory viruses
– Prevent spread of viruses and concerned vectors (mosquitoes)
– Prevent outbreaks of zoonotic viruses with an existing risk in the region
– Provide risk assessment of the emerging viruses (transmission,
spread, human impact...)
• Promote knowledge development and transfer of biosafety best
laboratory practices
• Improve integrated multi-sectorial surveillance (animal, human,
entomological)
7. Preventing Vector Borne Diseases around the Mediterranean &
Black Sea Regions by creating laboratory networks
Albania
Algeria
Armenia
Bosnia and Herzegovina
Egypt
Georgia
Jordan
Kosovo
Lebanon
Libya
Moldova
Montenegro
Morocco
Palestine
Serbia
Macedonia
Tunisia
Turkey
Ukraine
Beneficiary countries (19)
9. Selection Criteria
• Reference laboratory
• Being part of a national (emergency) team
• Priority to laboratories with both capacities:
arboviruses and respiratory viruses
• Diagnostic performance (PCR and serology)
• Basic laboratory equipment and lab capacities
• Existence of quality control procedures, lab SOPs
• Regional influence
66 applicants in 19 countries
10. Selection of participating laboratories:
Albania (3), Algeria (3), Armenia (3), Bosnia and Herzegovina (3),
Egypt (3), Georgia (3), Jordan (3), Kosovo(3), Lebanon (3), Libya
(2) Moldova(2) , Montenegro (3) Morocco(4) Palestine (3)
Republic of Macedonia (3), Serbia (3), Tunisia (3),Turkey (3),
Ukraine (3) = 55
Selected Laboratories
11. Objectives:
Inform participants about the network, its organization,
objectives and selection process
Better overview of the capacity and needs in partner
countries
Contribute to the roadmap for the next training sessions
Networking, exchange of experience according to the
different disciplines
32 participants from 16 countries
Heads of Labs meeting
IP Paris, 14 – 15 January 2015
15. Outcomes of Heads of Lab
meeting (4) MERS-CoV
Specimen collection
General diagnostics of MERS-CoV
Case studies
Sequence analysis
16. Improve the diagnosis and understanding of the different zoonotic
viruses existing in the regions (West Nile, Crimean Congo
Haemorrhagic fever, RVF, Corona, etc.. ) by Training sessions.
Improve the level of biosafety in the laboratories
Enhance the networking among participating laboratories
WP2: Animal Virology
CISA-INIA, Madrid, Spain
Miguel-Angel Jimenez – Elisa Ramirez
WP3: Human Virology
Institut Pasteur, Paris, France
Jean-Claude Manuguerra & Camille Escadafal
17. Systematic identification and geographical mapping of
major vectors of viruses found prevalent or potentially
present in the region.
Making available of a web-based determination key
Outline of Specific country/region-tailored measures for
control of mosquito vectors.
Regional Training sessions
WP4: Medical Entomology
IRD, Montpellier, France
Vincent Robert & Marie Picard
19. Challenges for the future
15-17 December 2015 – Institut Pasteur, Paris (France) joining different disciplines
meeting with special focus on risk assessment gathering
3 continents with different health systems: Regional meetings
Foster common databases (provide tools)
External Quality Assurance Excercises
Exchange of Scientists and Experts on identified gaps
E.g. Sending of experts to outbreak areas e.g. Goarn/MediLabSecure expert to
Jordan for MERS-Co Outbreak
20. Facilitate integrated surveillance, risk assessment
and early case detection across the different project’s
areas of activity.
Guidelines on the level of integration between
animal, human virology and medical entomology
surveillance for existing and potential diseases in the
Region
WP5: Public health
ISS, Rome, Italy
Silvia Declich, Maria Gracia Dente, Flavia Riccardo
23. Thank you
The MediLabSecure Project is supported by the European Commission (DEVCO: IFS/21010/23/_194)The MediLabSecure Project is supported by the European Commission (DEVCO: IFS/21010/23/_194)
Hinweis der Redaktion
Due to the multidisciplinary nature of the project and network (animal, human and entomology) the biosafety modules will be approached in an interdisciplinary way.
Project counseled by an Advisory Board composed by EC, ECDC, WHO, OIE and other international experts.
The consortium led by the Institut Pasteur, France
Episouth Plus aimed at creating a framework of collaboration on epidemiological issues in order to improve communicable diseases surveillance, communication and training across the countries of the Mediterranean and the Balkans.
Due to the multidisciplinary nature of the project and network (animal, human and entomology) the biosafety modules will be approached in an interdisciplinary way.
Project counseled by an Advisory Board composed by EC, ECDC, WHO, OIE and other international experts.
The consortium led by the Institut Pasteur, France
The project is based on the foundations put in place by the Episouth-Plus project, which included a work package on establishment of a regional reference laboratory Network
Selection criteria:
Reference laboratory
Being part of a national emergency team
Priority to laboratories with both capacities: arboviruses and respiratory viruses
Diagnostic performance (PCR and serology)
Basic laboratory equipment and lab capacities
Existance of quality control procedures, lab SOPs
Regional influence
Right now all WPs are busy with the selection of participating laboratories.
Right now all WPs are busy with the selection of participating laboratories.
Right now all WPs are busy with the selection of participating laboratories.
Right now all WPs are busy with the selection of participating laboratories.
Right now all WPs are busy with the selection of participating laboratories.
Right now all WPs are busy with the selection of participating laboratories.
The WP2 is the animal virology part coordinated by Miguel form the INIA
CENTRO DE INVESTIGACION EN SANIDAD ANIMAL (CISA)
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA)
As I said the biosafety training will be approached in a interdisciplinary way
The 4th WP is the Medical Entomolgy WP with… at the Institute for Research and development…
Potential viruses including West Nile, dengue, Chikungunya, Rift valley fever, CCHF viruses and other relevant strains arbovirus.
Selection criteria:
Reference laboratory
Being part of a national emergency team
Priority to laboratories with both capacities: arboviruses and respiratory viruses
Diagnostic performance (PCR and serology)
Basic laboratory equipment and lab capacities
Existance of quality control procedures, lab SOPs
Regional influence
Right now all WPs are busy with the selection of participating laboratories.
The last WP integrates and assesses the overall impact of the activities of each WP.
The main objective is to…
More specifically they will…
Right now all WPs are busy with the selection of participating laboratories.