SN1 SN2 NUCLEOPHILLIC SUBSTITUTION REACTION STEREO SELECTIVE REACTIONS

1. STEREO SELECTIVE SN1 SN2
REACTIONS

2. YOGI SIR CHEMISTRY

3. YOGI SIR CHEMISTRY

4. Different Types of SN Reactions
YOGI SIR CHEMISTRY

5. YOGI SIR CHEMISTRY

6. YOGI SIR CHEMISTRY

7. YOGI SIR CHEMISTRY

8. YOGI SIR CHEMISTRY

9. Waldens Inversion
YOGI SIR CHEMISTRY

10. YOGI SIR CHEMISTRY

11. YOGI SIR CHEMISTRY

12. YOGI SIR CHEMISTRY

13. YOGI SIR CHEMISTRY

14. YOGI SIR CHEMISTRY

15. YOGI SIR CHEMISTRY

16. YOGI SIR CHEMISTRY

17. YOGI SIR CHEMISTRY

18. Waldens Inversion
YOGI SIR CHEMISTRY

19. YOGI SIR CHEMISTRY

20. YOGI SIR CHEMISTRY

21. YOGI SIR CHEMISTRY

22. YOGI SIR CHEMISTRY

23. Some Important points for SN-2 Reaction:
(i) Reactivities of alkyl halides in SN2 substitution is governed
by steric factors.
The bulkier the group, that less reactive it will be.
(ii) Reactivity order of alkyl halide varies as follows :
CH3X > 1°halide > 2°halide > 3° halide
(iii) The order of reactivity among 1° alkyl halides is :
CH3X > C2H5X > C3H7X ….etc.
Remember that in case alkyl halide is optically active,
SN2 reactions lead to Walden inversion.
(iv) Thus in short 3° alkyl halides react by SN1 ,1° by SN-2 and
2° by either or both of them SN1 and SN2 depend on the
nature of the R-X and the reagents, Solvents.
YOGI SIR CHEMISTRY

24. (v) For a given alkyl group the order of reactivity is –
(for SN1 and SN2 both) : RI > RBr > RCl > RF
(vi) In addition to substitution reaction alkyl halide also
undergo elimination reactions to form alkene with the
removal of molecule of hydrogen halide that is
(dehydrohalogenation).
In dehydrohalogenation, hydrogen and halogen atoms are
eliminated from two adjacent carbon atoms, the reaction
also known as elimination may proceed by E1 & E2 mechanism
(analogous to SN1 and SN2 mechanism).
The order of elimination reaction is :
3° halides > 2° halides > 1° halides
(vii) In general 3° halides tend to react by elimination;
1° halides by substitution and 2° halides by either or
both of the reactions. YOGI SIR CHEMISTRY

25. YOGI SIR CHEMISTRY

26. Nucleophillic Substitution
Reaction
SN-1 Unimolecular Reaction
YOGI SIR CHEMISTRY

27. YOGI SIR CHEMISTRY

28. YOGI SIR CHEMISTRY

29. YOGI SIR CHEMISTRY

30. YOGI SIR CHEMISTRY

31. YOGI SIR CHEMISTRY

32. YOGI SIR CHEMISTRY

33. YOGI SIR CHEMISTRY

34. YOGI SIR CHEMISTRY

35. YOGI SIR CHEMISTRY

36. YOGI SIR CHEMISTRY

37. YOGI SIR CHEMISTRY

38. YOGI SIR CHEMISTRY

39. YOGI SIR CHEMISTRY

40. YOGI SIR CHEMISTRY

41. YOGI SIR CHEMISTRY

42. YOGI SIR CHEMISTRY