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Working Toward Zero  Infection Rate ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Disclosure: Ethicon and Cardinal Health Speaker’s Bureau
Topics: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
NEBH SSI Rates 2003 – 2010 (outpatient and inpatient infections)
Orthopedic Surgical Site Infection ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
2003 - Established a Multidisciplinary Team ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Team Intent:   Zero Healthcare-associated Infections The teams:  SSI, VAP, CLABSI, UTI, MRSA, C.difficile Books:  Power Versus Force  – David Hawkins, MD 48 Laws of Power  – Robert Greene
Issues Identified By Team  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Operating Room -  2003 ,[object Object],[object Object],[object Object]
Operating Room -  2003 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Too many in this room, hair not adequately covered
Lab Coat Contamination ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Peri-operative Environmental  Evaluation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Complicated Orthopedic Instruments ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Environmental Upgrades ,[object Object],[object Object],[object Object],[object Object]
Operating Room - 2004 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Infection Control - 2005
FY05 Operating Room ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Environmental Disinfection ,[object Object],[object Object],[object Object]
Environmental Disinfection ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],APIC 2007 – Poster Presentation:  M Spencer:  “Microbiologic Evaluation of a Silver Antimicrobial Disinfectant Spray”  APIC San Jose, June 2007
Environmental Disinfection ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Patient Risk Factors
Prosthetic Joint Infection Risk Factors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MRSA and Staph aureus  Eradication Program ,[object Object],[object Object],[object Object],Kim D, Spencer M, Davidson S, et al. J Bone Joint Surg Am. 2010;92:1820-6
February 2006  Obtained Anonymous Nares Cultures To Prove to Administration They Come In With Staph aureus and MRSA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Implemented Decolonization Protocol ,[object Object],[object Object],[object Object],[object Object]
AORN Journal –Nov 2008 Vol 88, Nov. pages 818-820 “ Dealing with Antibiotic Resistant Organisms”
AORN ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MRSA/MSSA Eradication Results ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],% MRSA and  Staph aureus  SSI
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],% MRSA SSI in  MRSA +  Screened Patients
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],%  Staph aureus (MSSA)  SSI in  Screen + Patients
FDA Cleared “Innovative Technologies" ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Sample of Chlorhexidine Products for Healthcare Use   BSI = bloodstream infection; CHG = chlorhexidine gluconate; ICU = intensive care unit; SSI = surgical site infection   Product   Format   CHG Concentration   Healthcare Uses   Topical solution Sponge applicators Swab sticks Ampules 2% or 3.15% With 70% isopropyl alcohol Skin preparation for surgery, invasive procedures, central lines to prevent SSI and BSI Scrub solution Liquid detergent (sudsing base) 2% or 4% aqueous Preoperative showering/bathing General skin cleansing Washcloth Impregnated single-use washcloth/wipe 2% aqueous Daily bathing in ICU patients Dental solution Oral rinse 0.12% Decontaminate oral cavity (ventilator-associated pneumonia prevention protocols) Gauze dressing Cotton-weave gauze dressing 0.5% with paraffin Wounds or burns Catheter dressing CHG pad or integrated with semi-permeable transparent dressing 2% gel pad or foam disk Peripherally inserted central catheters Central line dressings Hand rub Waterless antiseptic hand gel 1% alcohol based with emollients Hand sanitizer for healthcare personnel (nonsoiled hands)
New CHG Irrigation Solution  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Antisepsis with Chlorhexidine ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
OR Air Current Contamination In teaching hospitals: Surgeon leaves room Resident, Physician Assistant or Nurse Practitioner work on incision Circulating Nurse counts sponges and starts room breakdown Scrub Technician starts breaking down tables and preparing instruments for Central Processing Anesthesia move in and out of room Instrument representative might leave room Visitors may leave room
Suture with Staphylococcus colonies Air settling plates in the operating room at the last hour of a total joint case Potential for Contamination of Sutures at End of Case
NEBH Antibacterial Suture  Staph aureus Culture Plate Study ,[object Object],[object Object],[object Object],[object Object],[object Object],5 day zone of inhibition 10 day zone of inhibition
2005 – New England Baptist Hospital One Year Prospective Study of  3800 Total Joints and Antimicrobial Sutures ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IRGACARE ®  MP (triclosan) Properties ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],USP=United States Pharmacopeia. Zurita R et al.  Macromol Biosci.  2006;6:58-69. Ming Xet al.  Surg Infect (Larchmt).  2007;8:201-207. Ming X et al.  Surg Infect (Larchmt).  2008;9:451-457. Barbolt TA.  Surg Infect (Larchmt).  2002;3(suppl 1):S45-S53 .
[object Object],[object Object],[object Object],[object Object],[object Object],IRGACARE MP-Coated Sutures: In Vitro Activity 1 Rothenburger S, et al.  Surg Infect (Larchmt).  2002;3(suppl 1):S79-S87. 2 Edmiston CE, et al.  J Am Coll Surg.  2006;203:481-489. Suture without IRGACARE MP Suture with IRGACARE MP
IRGACARE ®  MP (triclosan): Mode of Action ,[object Object],[object Object],[object Object],[object Object]
Why IRGACARE ®  MP (triclosan)? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IRGACARE ®  MP (triclosan): Pharmacokinetics ,[object Object],[object Object],[object Object],[object Object],[object Object]
IRGACARE ®  MP (triclosan) and Microbial Resistance ,[object Object],[object Object],[object Object],[object Object],[object Object],Ming X et al.  Surg Infect (Larchmt).  2007;8:209-213. Barbolt TA.  Surg Infect (Larchmt).  2002;3(suppl 1):S45-S53. Ford HR et al.  Surg Infect   (Larchmt).  2005;6:313-321.
Articles Related To Antibacterial Sutures ,[object Object],[object Object],[object Object],[object Object]
Protect OR Staff: ETHIGUARD* Blunt Point Needles ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],* Trademark TPB-1: 65 mm SHB: 26 mm CTB-1: 36 mm CTXB: 48 mm CTB-2: 26 mm CTB: 40 mm
INCISIONAL SKIN ADHESIVE TO PREVENT EXOGENOUS CONTAMINATION TO INCISION DURIN G POST-OP PERIOD
Skin Issues in Orthopedics Anterior fusion with tape burns Posterior fusion with contaminated steri-strips Contaminated steri-strips
We Do Not Recommend Incisions opened to air with contaminated steristrips Bacteria feed off blood (and sugar) Incisions are in exudative stage of wound healing first few post-op days  Sent home on day 3- 4 with incision and underlying tissues starting proliferative stage of wound healing Wounds are susceptible to dehiscence
Obesity and Surgical Incision ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Octyl-Cyanoacrylate Topical Skin Adhesive ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],1. Quinn, JV  Tissue Adhesives in Wound Care,  BC Decker  1998. Attached are chapters from the book.
Mechanism of action  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],OCA: 300-500 microns thick  compared to other N- Butyls at : <50 microns thick
Benefits for surgeons, nurses, patients, and hospitals ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Incisional Adhesive on Total Knee Incision
Incisionial Adhesive and AMD Dressing Knee : Sealed with Dermabond, covered with antimicrobial Telfa and a transparent dressing  Hip:  Sealed with Dermabond, covered with antimicrobial gauze and transparent dressing Healed incision
If Incisional Adhesive is Not used:  Antimicrobial Post-op Dressings ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
No More Flimsy Post-op Dressings  ABD with Paper or Gauze Tape ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
2008  Standardization: Antimicrobial Dressing (AMD) By Nursing Staff AMD secured with MeFix tape for protection from exogenous contamination and prevention of tape burn Allow skin/incision to  create proper temperature beneath dressing to enhance wound healing Protect the incision from exogenous contamination  until discharge Protect the incision from trauma Incision protected until discharge and  then 48 hrs post-op
Knee Dressings with Ace Ace bandage one day post-op with blood strikethrough after drain removed – nurses told to “reinforce” – another reason to have antimicrobial gauze beneath the ace bandage.  Initial post-op dressing is usually an ace wrap for compression. AMD gauze are in post-op dressing kits to offer protection to the incision in first two days
Spine Service and Shoulders AMD sealed with Tegaderm left on until discharge AMD Island dressing – left on until discharge Rotator cuff (and total shoulders) – Dermabond is being used or an AMD gauze covered by tegaderm – left on until discharge
Practices with Limited Supporting Data
  Surgical Incise Drapes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Bacitracin/Polymixin Irrigation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
UTI Prevention ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Our Experience and Evidence
OR Cleanup Bundle Approach to Reducing SSI
NEBH SSI Rates 2003 – 2010 (outpatient and inpatient infections)
Creative and Fun Hand Hygiene Educational Programs Infection Control - $7000.00/year budget
Most Important Control Measure ,[object Object],[object Object]
Alcohol Foam, Liquid and Hand Wipes All patients receive package of alcohol wipes in admission kit – encourage them to sanitize hands Foam or liquid sanitizer In each patient room, outside rooms, cafeteria and other areas Wash hands often – before eating, before leaving work, after contamination
Got Soap? -  Engage Your Staff!! ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Patient and Visitor Empowerment Routine Cafeteria Displays
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Be Creative – Make it Fun
Creative and Interactive   Glo-Germ   “Bug Beat” Fair   Contact    Plates
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],M.R.S.A . Fair – Program Make Resistance Stay Away
2007
2007
2008
 
Hand Hygiene Observations
Tools for Success ,[object Object],[object Object],[object Object],[object Object],[object Object]
Thank You

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Periop conference working toward zero ssi - sep 11 2010

  • 1.
  • 2.
  • 3. NEBH SSI Rates 2003 – 2010 (outpatient and inpatient infections)
  • 4.
  • 5.
  • 6. Team Intent: Zero Healthcare-associated Infections The teams: SSI, VAP, CLABSI, UTI, MRSA, C.difficile Books: Power Versus Force – David Hawkins, MD 48 Laws of Power – Robert Greene
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  • 26. AORN Journal –Nov 2008 Vol 88, Nov. pages 818-820 “ Dealing with Antibiotic Resistant Organisms”
  • 27.
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  • 30.
  • 31.
  • 32.
  • 33. Sample of Chlorhexidine Products for Healthcare Use BSI = bloodstream infection; CHG = chlorhexidine gluconate; ICU = intensive care unit; SSI = surgical site infection Product Format CHG Concentration Healthcare Uses Topical solution Sponge applicators Swab sticks Ampules 2% or 3.15% With 70% isopropyl alcohol Skin preparation for surgery, invasive procedures, central lines to prevent SSI and BSI Scrub solution Liquid detergent (sudsing base) 2% or 4% aqueous Preoperative showering/bathing General skin cleansing Washcloth Impregnated single-use washcloth/wipe 2% aqueous Daily bathing in ICU patients Dental solution Oral rinse 0.12% Decontaminate oral cavity (ventilator-associated pneumonia prevention protocols) Gauze dressing Cotton-weave gauze dressing 0.5% with paraffin Wounds or burns Catheter dressing CHG pad or integrated with semi-permeable transparent dressing 2% gel pad or foam disk Peripherally inserted central catheters Central line dressings Hand rub Waterless antiseptic hand gel 1% alcohol based with emollients Hand sanitizer for healthcare personnel (nonsoiled hands)
  • 34.
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  • 36.  
  • 37. OR Air Current Contamination In teaching hospitals: Surgeon leaves room Resident, Physician Assistant or Nurse Practitioner work on incision Circulating Nurse counts sponges and starts room breakdown Scrub Technician starts breaking down tables and preparing instruments for Central Processing Anesthesia move in and out of room Instrument representative might leave room Visitors may leave room
  • 38. Suture with Staphylococcus colonies Air settling plates in the operating room at the last hour of a total joint case Potential for Contamination of Sutures at End of Case
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  • 49. INCISIONAL SKIN ADHESIVE TO PREVENT EXOGENOUS CONTAMINATION TO INCISION DURIN G POST-OP PERIOD
  • 50. Skin Issues in Orthopedics Anterior fusion with tape burns Posterior fusion with contaminated steri-strips Contaminated steri-strips
  • 51. We Do Not Recommend Incisions opened to air with contaminated steristrips Bacteria feed off blood (and sugar) Incisions are in exudative stage of wound healing first few post-op days Sent home on day 3- 4 with incision and underlying tissues starting proliferative stage of wound healing Wounds are susceptible to dehiscence
  • 52.
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  • 56. Incisional Adhesive on Total Knee Incision
  • 57. Incisionial Adhesive and AMD Dressing Knee : Sealed with Dermabond, covered with antimicrobial Telfa and a transparent dressing Hip: Sealed with Dermabond, covered with antimicrobial gauze and transparent dressing Healed incision
  • 58.
  • 59.
  • 60. 2008 Standardization: Antimicrobial Dressing (AMD) By Nursing Staff AMD secured with MeFix tape for protection from exogenous contamination and prevention of tape burn Allow skin/incision to create proper temperature beneath dressing to enhance wound healing Protect the incision from exogenous contamination until discharge Protect the incision from trauma Incision protected until discharge and then 48 hrs post-op
  • 61. Knee Dressings with Ace Ace bandage one day post-op with blood strikethrough after drain removed – nurses told to “reinforce” – another reason to have antimicrobial gauze beneath the ace bandage. Initial post-op dressing is usually an ace wrap for compression. AMD gauze are in post-op dressing kits to offer protection to the incision in first two days
  • 62. Spine Service and Shoulders AMD sealed with Tegaderm left on until discharge AMD Island dressing – left on until discharge Rotator cuff (and total shoulders) – Dermabond is being used or an AMD gauze covered by tegaderm – left on until discharge
  • 63. Practices with Limited Supporting Data
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  • 67. Our Experience and Evidence
  • 68. OR Cleanup Bundle Approach to Reducing SSI
  • 69. NEBH SSI Rates 2003 – 2010 (outpatient and inpatient infections)
  • 70. Creative and Fun Hand Hygiene Educational Programs Infection Control - $7000.00/year budget
  • 71.
  • 72. Alcohol Foam, Liquid and Hand Wipes All patients receive package of alcohol wipes in admission kit – encourage them to sanitize hands Foam or liquid sanitizer In each patient room, outside rooms, cafeteria and other areas Wash hands often – before eating, before leaving work, after contamination
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  • 76. Creative and Interactive Glo-Germ “Bug Beat” Fair Contact Plates
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  • 78. 2007
  • 79. 2007
  • 80. 2008
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Hinweis der Redaktion

  1. It is my pleasure to be here today to present to you the work at New England Baptist Hospital in working toward a zero infection rate.
  2. The topics I will be covering include a brief overview of NEBH, what’s up in the healthcare community related to infection control, A brief overview of the epidemiology of HAI and SSI, efforts to eliminate SSIs, surveillance data, problems we identified and action plans, the cost of HAI, action plans for patients, the outcomes and cost savings and future steps for NEBH
  3. The next set of slides with take you on a journey into the field of infection control and all the areas of focus and investigation that Occurred from 2003-2005.
  4. Cost saving measure in 2002 was to outsource EVS We worked with each department to write all the equipment that needed to be cleaned, how often and with what type of
  5. © ETHICON, INC. 2009
  6. Chlorhexidine antiseptic wash (Bactoshield) for pre-op shower Annual cost: $10,639 Chlorhexidine swabs for central line insertion site (Chloraprep) Use clippers rather than razors to remove hair at incision site Annual cost: $8,175
  7. This is a picture of bacterial adherence to non –T riclosan-coated suture material.
  8. Suture cost increased from ~ $31,000 to $37,000 Vicryl Plus sutures for all surgeries Additional annual cost: $5,572
  9. Note: IRGACARE ® MP (triclosan) is a biocidal agent used in all Plus SUTURES products IRGACARE MP is a high-purity material that meets United States Pharmacopeia specifications for triclosan and contributes minimally to the background exposure to toxic residues It has demonstrated antibacterial efficacy and a long history of safety. IRGACARE MP is active against the most common pathogens implicated in SSIs, including S aureus , S epidermidis , and others IRGACARE MP is also a great candidate for incorporation into sutures because of its compatibility with suture processing
  10. © ETHICON, INC. 2009
  11. Note: The mode of action of triclosan is widely unknown The triclosan used in Plus SUTURES is the highly purified form, IRGACARE ® MP Recent studies have shown that it acts as a competitive inhibitor of an essential enzyme in fatty acid synthesis: enoyl-acyl carrier protein reductase
  12. Note: IRGACARE ® MP (triclosan) withstands manufacturing processes, is cost-effective, and has excellent physical and functional properties Coated polyglactin 910 sutures with triclosan appeared to exhibit no difference from traditional polyglactin 910 sutures with respect to tactile smoothness, dry tie-down, and wet tie-down
  13. Note: IRGACARE ® MP (triclosan) has favorable pharmacokinetic properties. It is well absorbed (50% – 100%) by the gastrointestinal tract and well distributed in the body It binds to serum albumin and is present as the sulfate and/or glucuronide conjugate, depending on exposure There is no indication that triclosan accumulates in plasma over time, nor is it stored after single or repeated exposure
  14. Note: IRGACARE ® MP (triclosan) has favorable pharmacokinetic properties. It is well absorbed (50% – 100%) by the gastrointestinal tract and well distributed in the body It binds to serum albumin and is present as the sulfate and/or glucuronide conjugate, depending on exposure There is no indication that triclosan accumulates in plasma over time, nor is it stored after single or repeated exposure
  15. Talking about the features and benefits that ETHIGUARD needles offer to surgeons. ETHIGUARD has better performance than conventional blunt needles which are used for soft tissue. Another key point is ETHIGUARD needles offer combinations with plus sutures.
  16. © ETHICON, INC. 2009 Skin adhesives Cyanoacrylates were first manufactured in 1949. The first adhesives were noted to have extreme inflammatory effects on tissues. n-butyl-2-cyanoacrylate, which was developed in the 1970s, was the first adhesive to have negligible tissue toxicity and good bonding strength, as well as acceptable wound cosmesis. DERMABOND Adhesive (2-Octyl-Cyanoacrylate), the latest in cyanoacrylate technology, has less toxicity and almost four times the strength of n-butyl-2-cyanoacrylate.
  17. © ETHICON, INC. 2009 “ Real World” benefits for use of DERMABOND Adhesive Physician: time savings in many situations Reduce needle stick exposure No followup needed to remove sutures more reassurance Increased patient satisfaction more difficult patients (geri, pedi, bedbound) building practice, marketing
  18. Iodophor/alcohol surgical prep is used – we evaluated the tinted CHG but surgeons did not like the product due to Its green color and inability to adhere the barrier drapes to the skin as well as the iodophor product – this is a big Issue for orthopedic surgeons
  19. warmer patients less likely to develop infection and silver/silicone urinary catheters are used to prevent postop UTIs
  20. Partners in Hand Hygiene: June-November – baseline data collected for the Partners in Your Care – Program out of Univ of Penn – 300 hospitals participating in patient education campaign November – cafeteria displays for staff to market the program, distribute scripts to staff in response to patients asking if they washed their hands, staff received small bottles of Cal Stat with a “own a bug” attached to it. December – posters in admitting office, brochures for each inpatient, small finger puppets of “bugs” distributed to patients Every two months data is collected on amount of product used by staff January – Let It Snow – gave out small snowmen in cafeteria displays April – Do the H.O.P. – raffled off bunnies, gave out small bunnies attached to Cal Stat