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Evidence-Based
Clinical Practice Guidelines
‘for Psychiatrists’
By
Dr. Yasser S. Amer
MBBCh, MPedia, MHI, CPHQ, FISQua, IPFPH
CPG Unit, QMD, KKUH
CPG Steering Committee, KSUMC
Research Chair for EBHC-KT
Pediatrics, KKUH
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 2
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 3
The EBM Triad
425/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer
Evidence-Based (Best Practice) Psychiatry
My Clinical
Experience
Best
evidence
Patient
values
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 5
Best Evidence
Evidence-Based
Psychiatry
CPGs
(Recommendati
ons + Evidence)
PIPOH
(CPG Websites)
Evidence
PICO
(EBM Websites)
Traditional
Textbooks
Journals
Experts
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 6
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 7
Evidence Pyramid
SR
RCT
Cohort
Case control
Case series
Case report
Expert opinion
I
II
III
IV
A
B
C
LevelsofEvidence
GradesofRecommendations
MA
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 8
The proposed new EBM pyramid.
M Hassan Murad et al. Evid Based Med 2016;21:125-127
©2016 by BMJ Publishing Group Ltd
New evidence pyramid
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 9
CPG-related Accreditation Standard(s)
Clinical practice guidelines,
pathways, and protocols are
developed or adopted to guide
priority care services.
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 10
25/11/2019 11
What makes a trustworthy CPG?
EB-CPGs for Psyhciatrists by Y. S. Amer
Standards for high quality CPGs
IOM 2011 – G-I-N 2012 – AGREE 2013
25/11/2019 12EB-CPGs for Psyhciatrists by Y. S. Amer
Standards for trustworthy CPGs
IOM 2011 G-I-N 2012
1- Establishing Transparency 1- Decision making process. 2- Methods
2- Management of COI 3- COI
3- (GDG) composition 4- GDG composition
4- (CPG – SR) intersection 5- Evidence reviews
5- Assign/ link to (LoE) & (GoR) 6- Rating of E & Rs
6- Articulation of (Rs) 7- CPG Rs (formulation/ wording)
7- External Review 8- Peer review & stakeholder consultation
8- Updating 9- Expiration & updating
10- Scope of CPG
11- Financial support/ sponsoring organization
25/11/2019 13EB-CPGs for Psyhciatrists by Y. S. Amer
GRADE
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 14
More than 100
organizations from 19
countries around the
world have endorsed
or are using GRADE
(e.g. WHO, ACP, BMJ,
ACCP, NICE, SIGN,
AHRQ, Cochrane, etc.)
GRADE: The Grading of
Recommendations Assessment,
Development and Evaluation
Types of CPGs
1.Evidence-Based CPGs (evidence-
based methodology)
2.Consensus/ expert-based CPGs
25/11/2019 15
Which type do you think is
better?
EB-CPGs for Psyhciatrists by Y. S. Amer
‫الجامعية‬‫الطبية‬‫المدينة‬-
KSUMC
Quality Management Department
Approach: Methodology (KSU Modified ADAPTE)
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 16
KSU Modified ADAPTE
25/11/2019 17EB-CPGs for Psyhciatrists by Y. S. Amer
Organization Name
Country
URL
Producer
Finder
FREE
PAID
Guidelines International Network
(G-I-N)
Int’l http://www.g-i-n.net F √ √
World Health Organization (WHO) Int’l http://www.who.int/topics P √
National Institute for Health
& Care Excellence (NICE)
UK
http://www.nice.org.uk/page.aspx?o=ourguidan
ce
P √ √
Scottish Intercollegiate Guidelines
Network (SIGN)
UK http://www.sign.ac.uk/guidelines/index.html P √
EBSCO Health: DynaMed USA http://www.dynamed.com/home/ F
ECRI Institute: Guidelines Trust USA
https://guidelines.ecri.org/
(successor for National Guidelines
Clearinghouse of AHRQ)
F √
MEDLINE/ PubMed USA
http://www.ncbi.nlm.nih.gov/pubmed
OR http://www.pubmed.gov
F
√
(Abstrac
ts)
√
(Full
Text)
Plus Specialized societies of psychiatry
25/11/2019 18
CPG online databases
EB-CPGs for Psyhciatrists by Y. S. Amer
Resources for Psych. CPGs
• American Psychiatric Association Practice
Guidelines.
• American Academy of Child & Adolescent
Psychiatry Practice Parameters and
Guidelines.
• Canadian Network for Mood and Anxiety
Treatment (CANMAT) Guidelines.
• The Maudsley Prescribing Guidelines (MPG).
• Saudi Psychiatric Association.
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 19
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 20
25/11/2019 21EB-CPGs for Psyhciatrists by Y. S. Amer
23 Items in 6 Domains
USER’S MANUAL page 7
DOMAINS No. of Items
1 Scope & Purpose 3
2 Stakeholder Involvement 3
3 Rigour of Development
(Methodology)
8
4 Clarity & Presentation 4
5 Applicability 3
6 Editorial Independence 2
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 22
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 23
Schizophrenia CPGs
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 24
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 25
Tic Disorders CPGs
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 26
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 27
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 28
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 29
Evidence-based CPGs developed by CANMAT and the
International Society for Bipolar Disorder (ISBD) for
Dx and Rx of Bipolar Disorders, designed for use by
community-based psychiatrists and mental health
professionals (2018)25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 30
CPGs Are Not Rules
• Expect the vast majority of practice to fall within
CPGs (80 % - 90 % Rule)
• Deviation from CPGs is allowed for specific patients
with specific circumstances.
• When such deviation occurs an individual clinician
is expected to explain the rationale.
• Strong evidence (Level 1 & 2) are expected to be
followed.
• Weaker evidence (Level 3 & 4) can be handled
differently .
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 31
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 32
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 33
Thank you for
Listening !
Email: yassersamiamer@gmail.com;
yamer@ksu.edu.sa
25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 34

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Evidence-Based Clinical Practice Guidelines ‘for Psychiatrists’

  • 1. Evidence-Based Clinical Practice Guidelines ‘for Psychiatrists’ By Dr. Yasser S. Amer MBBCh, MPedia, MHI, CPHQ, FISQua, IPFPH CPG Unit, QMD, KKUH CPG Steering Committee, KSUMC Research Chair for EBHC-KT Pediatrics, KKUH
  • 2. 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 2
  • 3. 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 3
  • 4. The EBM Triad 425/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer
  • 5. Evidence-Based (Best Practice) Psychiatry My Clinical Experience Best evidence Patient values 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 5
  • 6. Best Evidence Evidence-Based Psychiatry CPGs (Recommendati ons + Evidence) PIPOH (CPG Websites) Evidence PICO (EBM Websites) Traditional Textbooks Journals Experts 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 6
  • 7. 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 7
  • 8. Evidence Pyramid SR RCT Cohort Case control Case series Case report Expert opinion I II III IV A B C LevelsofEvidence GradesofRecommendations MA 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 8
  • 9. The proposed new EBM pyramid. M Hassan Murad et al. Evid Based Med 2016;21:125-127 ©2016 by BMJ Publishing Group Ltd New evidence pyramid 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 9
  • 10. CPG-related Accreditation Standard(s) Clinical practice guidelines, pathways, and protocols are developed or adopted to guide priority care services. 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 10
  • 11. 25/11/2019 11 What makes a trustworthy CPG? EB-CPGs for Psyhciatrists by Y. S. Amer
  • 12. Standards for high quality CPGs IOM 2011 – G-I-N 2012 – AGREE 2013 25/11/2019 12EB-CPGs for Psyhciatrists by Y. S. Amer
  • 13. Standards for trustworthy CPGs IOM 2011 G-I-N 2012 1- Establishing Transparency 1- Decision making process. 2- Methods 2- Management of COI 3- COI 3- (GDG) composition 4- GDG composition 4- (CPG – SR) intersection 5- Evidence reviews 5- Assign/ link to (LoE) & (GoR) 6- Rating of E & Rs 6- Articulation of (Rs) 7- CPG Rs (formulation/ wording) 7- External Review 8- Peer review & stakeholder consultation 8- Updating 9- Expiration & updating 10- Scope of CPG 11- Financial support/ sponsoring organization 25/11/2019 13EB-CPGs for Psyhciatrists by Y. S. Amer
  • 14. GRADE 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 14 More than 100 organizations from 19 countries around the world have endorsed or are using GRADE (e.g. WHO, ACP, BMJ, ACCP, NICE, SIGN, AHRQ, Cochrane, etc.) GRADE: The Grading of Recommendations Assessment, Development and Evaluation
  • 15. Types of CPGs 1.Evidence-Based CPGs (evidence- based methodology) 2.Consensus/ expert-based CPGs 25/11/2019 15 Which type do you think is better? EB-CPGs for Psyhciatrists by Y. S. Amer
  • 16. ‫الجامعية‬‫الطبية‬‫المدينة‬- KSUMC Quality Management Department Approach: Methodology (KSU Modified ADAPTE) 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 16 KSU Modified ADAPTE
  • 17. 25/11/2019 17EB-CPGs for Psyhciatrists by Y. S. Amer
  • 18. Organization Name Country URL Producer Finder FREE PAID Guidelines International Network (G-I-N) Int’l http://www.g-i-n.net F √ √ World Health Organization (WHO) Int’l http://www.who.int/topics P √ National Institute for Health & Care Excellence (NICE) UK http://www.nice.org.uk/page.aspx?o=ourguidan ce P √ √ Scottish Intercollegiate Guidelines Network (SIGN) UK http://www.sign.ac.uk/guidelines/index.html P √ EBSCO Health: DynaMed USA http://www.dynamed.com/home/ F ECRI Institute: Guidelines Trust USA https://guidelines.ecri.org/ (successor for National Guidelines Clearinghouse of AHRQ) F √ MEDLINE/ PubMed USA http://www.ncbi.nlm.nih.gov/pubmed OR http://www.pubmed.gov F √ (Abstrac ts) √ (Full Text) Plus Specialized societies of psychiatry 25/11/2019 18 CPG online databases EB-CPGs for Psyhciatrists by Y. S. Amer
  • 19. Resources for Psych. CPGs • American Psychiatric Association Practice Guidelines. • American Academy of Child & Adolescent Psychiatry Practice Parameters and Guidelines. • Canadian Network for Mood and Anxiety Treatment (CANMAT) Guidelines. • The Maudsley Prescribing Guidelines (MPG). • Saudi Psychiatric Association. 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 19
  • 20. 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 20
  • 21. 25/11/2019 21EB-CPGs for Psyhciatrists by Y. S. Amer
  • 22. 23 Items in 6 Domains USER’S MANUAL page 7 DOMAINS No. of Items 1 Scope & Purpose 3 2 Stakeholder Involvement 3 3 Rigour of Development (Methodology) 8 4 Clarity & Presentation 4 5 Applicability 3 6 Editorial Independence 2 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 22
  • 23. 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 23
  • 24. Schizophrenia CPGs 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 24
  • 25. 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 25
  • 26. Tic Disorders CPGs 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 26
  • 27. 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 27
  • 28. 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 28
  • 29. 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 29
  • 30. Evidence-based CPGs developed by CANMAT and the International Society for Bipolar Disorder (ISBD) for Dx and Rx of Bipolar Disorders, designed for use by community-based psychiatrists and mental health professionals (2018)25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 30
  • 31. CPGs Are Not Rules • Expect the vast majority of practice to fall within CPGs (80 % - 90 % Rule) • Deviation from CPGs is allowed for specific patients with specific circumstances. • When such deviation occurs an individual clinician is expected to explain the rationale. • Strong evidence (Level 1 & 2) are expected to be followed. • Weaker evidence (Level 3 & 4) can be handled differently . 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 31
  • 32. 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 32
  • 33. 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 33
  • 34. Thank you for Listening ! Email: yassersamiamer@gmail.com; yamer@ksu.edu.sa 25/11/2019 EB-CPGs for Psyhciatrists by Y. S. Amer 34

Hinweis der Redaktion

  1. The proposed new evidence-based medicine pyramid. (A) The traditional pyramid. (B) Revising the pyramid: (1) lines separating the study designs become wavy (Grading of Recommendations Assessment, Development and Evaluation), (2) systematic reviews are ‘chopped off’ the pyramid. (C) The revised pyramid: systematic reviews are a lens through which evidence is viewed (applied).