1. How is the GFR measured? What are the strengths and
ASSIGNMENTThe kidneys are highly vascular organs that filter the blood, removing wastes
for excretion and returning the rest of the blood to the vascular system. The functional units
of the kidneys are nephrons, each composed of a glomerulus and a tubule.How is the GFR
measured? What are the strengths and limitations of methods of determining GFR?Often an
incidental finding in children during a urinary tract infection workup, in vesicoureteral
reflux (VUR), urine flows from the bladder back up the ureters.Could you explain the
mechanism of action of this abnormality in children?