Presentatie knvi breed herzien

Efficiënt en systematisch
zoeken in bibliografische
databases
Donderdag 10 November
KNVI Congres 2016

Medische Bibliotheek Erasmus MC
food breast cancer management
Hoeveel hits verwacht je?
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5
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20.000
1.000.000

Variatie binnen een database

Systematic approach
(vitamins[mh] OR hormones[mh] OR vitamins[pa]
OR hormones[pa] OR vitamin*[tiab] OR
hormon*[tiab]) AND (Clinical Study [pt] OR
clinical medicine[mh] OR clinical*[tiab] ) AND
(dermatology[mh] OR dermatol*[tiab] OR skin
diseases[mh] OR skin disease*[tiab])

sf-36 OR short-form-36 OR eq-5d OR eq-6d OR eq5d OR eq6d OR itqol
OR (physical* NEAR/3 (activ* OR perform*)) OR (independent* NEAR/3
living) OR (social* NEAR/3 participat*)):ab,ti) AND ('cohort analysis'/exp
OR 'longitudinal study'/exp OR 'retrospective study'/exp OR 'prospective
study'/exp OR 'validation study'/exp OR 'validity'/exp OR 'sensitivity and
specificity'/exp OR 'clinical article'/de OR 'observational study'/de OR
'major clinical study'/de OR 'follow up'/de OR 'epidemiological data'/de OR
'case control study'/exp OR 'cross-sectional study'/exp OR (cohort* OR
longitudinal* OR retrospectiv* OR prospectiv* OR validat* OR validit* OR
(observation* NEAR/3 stud*) OR sensitiv* OR specific* OR 'follow* up*'
OR followup* OR epidemiolog* OR 'case control*' OR 'cross-
section*'):ab,ti) NOT ([animals]/lim NOT [humans]/lim)

Literatuuronderzoek 13 oktober 2016
Vertebral spinal fracture quality of life burden society
Embase.com 2192 2155
Medline Ovid 1576 342
Web of science 883 146
Cochrane 117 43
CINAHL EBSCO 337 66
Google scholar 200 184
Total 5305 2936
Embase.com 2192
('spine fracture'/exp OR (((spin* OR vertebr* OR lumba* OR thora* OR burst) NEAR/10
(fracture*))):ab,ti) AND ('quality of life'/exp OR 'health care cost'/de OR 'hospital cost'/exp OR
'cost effectiveness analysis'/exp OR 'cost benefit analysis'/exp OR 'return to work'/exp OR
'absenteeism'/exp OR 'medical leave'/de OR 'productivity'/de OR 'length of stay'/de OR 'daily life
activity'/exp OR 'activity of daily living assessment'/exp OR 'employment'/de OR 'employment
status'/de OR 'unemployment'/de OR 'home care'/de OR hospitalization/de OR 'psychological
aspect'/de OR ((qualit* NEAR/3 life) OR qol OR hrqol OR hrql OR ((care OR healthcare OR
hospital OR direct* OR indirect* OR effectiv* OR benefit* OR analys* OR constitut*) NEAR/3
(cost OR costs OR expenditure*)) OR ((return* OR back OR absen*) NEAR/3 work*) OR
absenteeis* OR productivit* OR (burden NEAR/6 (societ* OR patient* OR econom* OR financial*
OR individual* OR 'health care' OR healthcare OR health OR disease* OR illness* OR assess*))
OR ((short* OR length OR long* OR hospital*) NEAR/3 stay*) OR ((Disabilit* OR qualit* )
NEAR/3 Adjust* NEAR/3 Year*) OR DALY OR dalys OR QALY OR qalys OR ((medical OR sick
OR disab*) NEXT/1 leave) OR (dail* NEAR/3 (life OR living) NEAR/3 activit*) OR adl OR badl OR
iadl OR adls OR badls OR iadls OR employment OR (occupation* NEAR/3 stat*) OR unemploy*
OR 'home care' OR hospitali* OR ((psycholog* OR function*) NEAR/3 (impair* OR
disab*))):ab,ti) NOT (osteopor* NOT trauma*):ab,ti NOT ([Conference Abstract]/lim OR
[Letter]/lim OR [Note]/lim OR [Editorial]/lim) AND [english]/lim
Medline Ovid 1576
("Spinal Fractures"/ OR (((spin* OR vertebr* OR lumba* OR thora* OR burst) ADJ10 (fracture*))).ab,ti.)
AND ("Quality of Life"/ OR exp "Health Care Costs"/ OR "Cost-Benefit Analysis"/ OR exp "Costs and
Cost Analysis"/ OR "Return to Work"/ OR "absenteeism"/ OR "Sick Leave"/ OR "length of stay"/ OR
"Activities of Daily Living"/ OR exp "employment"/ OR exp "Home Care Services"/ OR exp
hospitalization/ OR psychology.xs. OR ((qualit* ADJ3 life) OR qol OR hrqol OR hrql OR ((care OR
healthcare OR hospital OR direct* OR indirect* OR effectiv* OR benefit* OR analys* OR constitut*)
ADJ3 (cost OR costs OR expenditure*)) OR ((return* OR back OR absen*) ADJ3 work*) OR
absenteeis* OR productivit* OR (burden ADJ6 (societ* OR patient* OR econom* OR financial* OR
individual* OR "health care" OR healthcare OR health OR disease* OR illness* OR assess*)) OR
((short* OR length OR long* OR hospital*) ADJ3 stay*) OR ((Disabilit* OR qualit* ) ADJ3 Adjust* ADJ3
Year*) OR DALY OR dalys OR QALY OR qalys OR ((medical OR sick OR disab*) ADJ leave) OR (dail*
ADJ3 (life OR living) ADJ3 activit*) OR adl OR badl OR iadl OR adls OR badls OR iadls OR
employment OR (occupation* ADJ3 stat*) OR unemploy* OR "home care" OR hospitali* OR
((psycholog* OR function*) ADJ3 (impair* OR disab*))).ab,ti.) NOT (osteopor* NOT trauma*).ab,ti. NOT
(letter OR news OR comment OR editorial OR congresses OR abstracts).pt. AND english.la.
Web of science 883
TS=(((((spin* OR vertebr* OR lumba* OR thora* OR burst) NEAR/9 (fracture*)))) AND (((qualit* NEAR/2
life) OR qol OR hrqol OR hrql OR ((care OR healthcare OR hospital OR direct* OR indirect* OR
effectiv* OR benefit* OR analys* OR constitut*) NEAR/2 (cost OR costs OR expenditure*)) OR
((return* OR back OR absen*) NEAR/2 work*) OR absenteeis* OR productivit* OR (burden NEAR/5
(societ* OR patient* OR econom* OR financial* OR individual* OR "health care" OR healthcare OR
health OR disease* OR illness* OR assess*)) OR ((short* OR length OR long* OR hospital*) NEAR/2
stay*) OR ((Disabilit* OR qualit* ) NEAR/2 Adjust* NEAR/2 Year*) OR DALY OR dalys OR QALY OR
qalys OR ((medical OR sick OR disab*) NEAR/1 leave) OR (dail* NEAR/2 (life OR living) NEAR/2
activit*) OR adl OR badl OR iadl OR adls OR badls OR iadls OR employment OR (occupation*
NEAR/2 stat*) OR unemploy* OR "home care" OR hospitali* OR ((psycholog* OR function*) NEAR/2
(impair* OR disab*)))) NOT (osteopor* NOT trauma*) ) AND LA=(english) AND DT=(article)
Google scholar
"spinal|vertebral fracture|fractures"
hrqol|hrql|cost|costs|expenditure|"return|back*work"|absenteeism|productivity|"burden*society|patient"|e
conomic|financial|"length*stay"|"quality*life|Years"|"daily*activities"|"activities*daily"|disability|disabilities

Tijd nodig voor zoekactie systematic review
median average
This study 1.2 hr 1.3 hr
Comparison 20 hr 27 hr

Medische Bibliotheek Erasmus MC 24
Wie zijn wij / wat doen wij?
Wichor Bramer | Gerdien de Jonge
Informatiespecialisten Medische Bibliotheek – Erasmus MC Rotterdam
w.bramer@erasmusmc.nl | @wichor | nl.linkedin.com/in/wichor
>300 systematische searches per jaar
>25 co-auteurschappen van reviews (link)

Wie zijn jullie?
Vakgebied (biomedisch / anders)
Zoekacties (waarvoor / hoeveel / hoe)
Databases / interfaces (pubmed / ovid / ebsco / ProQuest /
discoverytools / google scholar)
Thesaurus

Research question  exhaustive search
Systematic searching
1. Examining the research question
2. Identifying key terms
a. Thesaurus terms
b. Free text terms
3. Creating a basic search strategy
4. Optimizing the basic strategy
5. Translating the strategy between databases

The Research Question
Clear and focused

Clear and focused research question
How can gist knowledge of patients be measured
Is scopic stabilisation better than Bristow Latarjet for treating an Anterior
glenohumeral luxation with labrum injury (no ossale disorder) in a 20 YO
rugby player for recurrent luxation or other Patient Related Outcome
Measures
Dietary intake and cardiovascular disease
TOO VAGUE
TOO SPECIFIC
TOO BROAD

Clear and focused
Which articles can answer the question?

Facilitators and barriers in preconception care
Predictive factors for oronasal fistulas in children treated for clef lip
Which risk factors for later maternal and neonatal outcomes can be
detected by postnatal caregivers?

Clear and focused
Elements (Key Concepts):
- Watch our for Bias and Duplicates
- Which elements to use in search?

Elements : Bias
Very specific characteristics
Duration of breastfeeding and intelligence
Judgements
Poor family functioning, harsh parenting and bullying behavior

Elements : Duplicates
Pre-eclampsia AND pregnant AND women
Lichtenstein therapy AND inguinal hernias

Does eating broccoli help in the prevention of cancer
generalspecific
important
unimportant
Broccoli Cancer
Prevention
Broccoli CancerPrevention

Identifying thesaurus terms
One element  One thesaurus term
One element  More thesaurus terms (OR)
Multiple elements  One thesaurus term

Identifying thesaurus terms
One element  One thesaurus term
One element  Multiple thesaurus terms (OR)
Multiple elements  One thesaurus term
(neoplasm/ OR cancer mortality/) AND (mortality/ OR cancer
mortality/)
One element  Multiple thesaurus terms (AND)
(Bennett Fracture* OR (Fracture, Bone/ AND metacarpal bones/
AND thumb/))

Identifying free text words
Optimal sensitivity only by additionally searching in title / abstract:
 Relevant, non-inverted terms from synonyms/ entry terms

Observer varia*
Observer bias
Intraobserver varia*
Interobserver varia*

 Relevant, non-inverted terms from synonyms / entry terms
Shoulder: glenohumeral joint- humeroscapular joint- scapulo humeral joint-
scapulohumeral joint- articulatio humeri
 Relevant words / phrases from narrower terms

 Relevant, non-inverted terms from synonyms / entry terms
Shoulder: glenohumeral joint; humeroscapular joint; scapulo humeral joint;
scapulohumeral joint; articulatio humeri
 Relevant words / phrases from narrower terms
Colorectal Neoplasms: Colonic cancer; Cancer of Sigmoid; Rectum tumor; Anal
Neoplasms…etc…

Creating a basic search strategy

syntax
Embase.
com
Ovid PubMed EBSCO ProQuest WoS Scopus
thesaurus /exp Exp ../ [mh] MH …+ MESH#() - -
Title/
abstract
:ab,ti .ab,ti. [tiab]
(herhaal)
TI () OR
AB ()
TI,AB () TS=() TITLE-
ABS()
proximity NEAR/# ADJ# AND N# N/# NEAR/# W/#

Creating a basic search strategy
DEMO

Considerations
Explode a broad term or not?
Start exploded, be more specific if many irrelevant results appear
Truncate a term or not?
Truncate as much as possible, hardly noise (though not too short)
Phrases or proximity?
When available, use proximity, easier and more sensitive
How broad should proximity be?
Start with 3, increase in steps of 3 and evaluate new articles

Creating a basic search strategy (summary)
 Type code in Word
 Open an element with ()
 For emtree terms type ''/exp and paste term
 After pasting all emtree terms, type OR ():ab,ti within that element once
for free text words
 Type single word synonyms first
 Type (() NEAR/3 ()) somewhere in the document to reuse
 Copy (() NEAR/3 ()) into the ():ab,ti part search for phrase variants, and
add the words

Optimizing your strategy
Temporarily change the syntax and check words:
Per element, keeping the rest unchanged
 (emtree) NOT (free text)
 (free text) NOT (emtree)
DEMO

Translating between databases
Embase.com (Embase and Medline)
Thorough optimization of thesaurus terms and title / abstract terms in search strategy
Macro and edit thesaurus
Medline (Ovid incl ePub)
MeSH terms in PubMed / Optimization
Add extra terms Remove thesaurus
Cochrane library
Macro
Web-of-science
Macro
Scopus
Macro and edit
thesaurus
CINAHL (EBSCO)
edit
thesaurus
PsycINFO
(OvidSP)
Macro and edit
Google Scholar
Liliacs / Scielo / Popline / Trials
Registers / WorldCat
Basic search strategy with AND,
OR parentheses based on basic
Google terms
DEMO

Success factors
 Optimization techniques
 Macros for database translation
 Single-line search strategies

Single line approach or set numbers?
Well structured?
#1 brassica [mh]
#2 brassica* [tiab]
#3 broccoli [tiab]
#4 #1 OR #2 OR #3
#5 neoplasms [mh]
#6 neoplas* [tiab]
#7 cancer* [tiab]
#8 tumor* [tiab]
#9 #5 OR #6 OR #7 OR #8
#10 #4 AND #9
#11 animals[mh]
#12 humans[mh]
#13 #11 AND #12
#14 #11 NOT #13
#15 #10 NOT #14
58
Unstructured?
(“brassica” [mh] OR brassica*
[tiab] OR broccoli [tiab])
AND
(“neoplasms” [mh] OR neoplas*
[tiab] OR cancer* [tiab] OR
tumor* [tiab])
NOT
(animals[mh] NOT humans
[mh])
Well structured!

Success factors
 Database choice and order

Database combinaties

Success factors
 Database choice and order
 Direct feedback by researcher
 Creating queries in Word (watch out for spellchecker with truncation)
 Computer literacy
 Experience (be pro active)

Effect voor de organisatie
0
10
20
30
40
50
60
70
80
90
2010 2011 2012 2013 2014 2015 2016
NumberofpublishedSystematicReviewsby
ErasmusMC
not assisted
assisted but not
acknowledged
acknowledged
co-authored

Bedankt!
Vragen / Discussie

Increase Sensitivity (always)
 Add extra words
 Generalize specific elements
 Drop unimportant elements
 Split 1 element  2 elements
(mesh/subheading[mh])  (mesh[mh])
AND (subheading[sh])
(phrases  separate words)
 2 elements  1 element
(I) AND (C)  (I OR C)
 Temporarily broaden or drop a
very specific element to optimize the
others
 Save relevant hits on clipboard!
Increase Specificity (if necessary)
 Add an extra element
 2 elements  1 element
([mh]) AND ([sh])  (mh/sh[mh])
(combine words into phrases)
 1 element  2 elements
(I OR C)  (I) AND (C)
 Add Filters for date?
or language?
If you can afford missing relevant refs:
 For the most important element: use [mj]
and [ti] instead of [mh] and [tiab]
and mesh/sh[mj] instead of [sh]

Major terms

Understanding the research question
What is the Cell contribution to chondroid / endochondreal /
intramembranous bone formation
((('bone development'/de OR 'bone mineralization'/de OR 'bone maturation'/de OR
ossification/de OR 'bone conduction'/de OR 'bone transplantation'/exp OR 'bone
matrix'/exp OR 'bone growth'/exp OR 'bone remodeling'/de OR ((bone NEAR/6
(minerali* OR develop* OR format* OR synthesis* OR growth* OR graft* OR
transplant* OR engineer* OR defect* OR matri* OR remodel* OR conduct* OR
maturat*)) OR osteogen* OR ossificat*):ab,ti) AND (chondroid* OR transchondroid*
OR enchondr* OR endochondr* OR intermembran* OR cartilagin* OR (inter NEXT/1
membran*)):ab,ti) OR 'enchondral ossification'/de) AND ('cell death'/de OR 'cell
survival'/de OR apoptosis/de OR 'cell differentiation'/de OR 'cell fate'/de OR 'host
cell'/de OR 'cell lineage'/de OR (((cell* OR msc OR osteoblast* OR osteocyte* OR
osteoclast* OR preosteoblast*) NEAR/3 (death OR senescen* OR contribut* OR
differentiat* OR fate OR plasticit* OR reprogram* OR donor* OR host* OR recruit*
OR surviv* OR viabilit* OR lineage*)) OR apoptosis):ab,ti)

Aantal includes

Aantal hits

Precisie

Presentatie knvi breed herzien

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