Cloning the gene responsible for alkaptonuria: An example from start to finish</TITLE

Other forms of cloning and analysis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

What PCR can do ,[object Object],[object Object],[object Object],[object Object]

PCR advantages over cloning ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

PCR disadvantages ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Restriction mapping ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

The human genome project ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

The approaches to cloning the human genome ,[object Object],[object Object],[object Object]

The NIH approach ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

The Celera approach ,[object Object],[object Object]

In situ hybridization techniques ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Mi c r ode l e t ion Syndromes

Sister chromatid exchange (SCE) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Detecting SCE ,[object Object],[object Object],[object Object],[object Object]

Detecting SCE II ,[object Object],[object Object],[object Object],Normal High frequency SCE

Genbank ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Homogentisic acid 1,2 dioxygenase (Or HGO to the cognoscenti) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Fast forward 84 years to 1992 ,[object Object],[object Object],[object Object],[object Object]

Confirmation of a successful clone-by-phone ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Further studies ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

An ethical dilemma ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Cloning the gene responsible for alkaptonuria: An example from start to finish</TITLE

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Cloning the gene responsible for alkaptonuria: An example from start to finish</TITLE