Presentation done at CBEB'16 the 17th October by Vicente Traver introducing EIP-AHA and H2020 policies, the LINK project and different opportunities to cooperate together between Brazil and EU about telehealth and personal health

1. LINK
Linking Excellence in Biomedical knowledge
and Computational Intelligence Research for
personalized management of CVD within PHC
FOZ DO IGUAÇU, 17TH OCTOBER 2016
A. MARTÍNEZ-ROMERO
V. TRAVER
ANALYSIS OF EU – BRAZIL COOPERATION
OPPORTUNITIES ON TELEHEALTH

2.  The EU CONTEXT
 The LINK Project
 Analysis of opportunities
Big OPPORTUNITY TO
STRENGTHEN COOPERATIONSHIP
BETWEEN BRAZIL AND EU

4. 0 25 65 years
IllnessPre-IllnessWellness
Crowd Achievable Health
Crowd Actual Health Outcomes
Death
60-80% Preventable
Modern Crowd health landscape
Age

5. The silver economy

6. The silver economy

7. The silver economy

8. The silver economy

9. The silver economy

10. Prevention, screening
& early diagnosis
Care & Cure Active ageing &
independent living
•Health literacy, patient
empowerment, ethics and
adherence
•Personal health
management
•Prevention, early
diagnosis of functional
and cognitive decline
•Guidelines for care,
workforce
(multimorbidity,
polypharmacy, frailty
and collaborative care)
•Multimorbidity and R&D
•Capacity building and
replicability of successful
integrated care systems
•Assisted daily living for
older people with
cognitive impairment
•Flexible and
interoperable ICT
solutions for active and
independent living
•Innovation improving
social inclusion of older
people
Vision / Foundation
•Focus on holistic and multidisciplinary approach
•Development of dynamic and sustainable care
systems of tomorrow
•New paradigm of ageing
•Innovation in service of the elderly people
•Regulatory and standardisation conditions
•Effective funding
•Evidence base, reference examples, repository for age-friendly
innovation
•Marketplace to facilitate cooperation among various stakeholders
Horizontal issues
European Innovation Partnership – Active and
Healthy Ageing

13. Implementation
Participation in the EIP-AHA initiative can happen
through:
• Commitment. Interested in the deployment of specific
actions
• Reference sites. Places where differents specific
action are already deployed in a integrated approach.
• Marketplace. Innovative ideas.

15. • Research and innovation action
• Innovation action
• Coordination and support action
• SME-instrument; incl. fast track to innovation
• Pre-commercial procurement co-fund actions
• Public procurement of innovative solutions
• ERA-Net co-fund
• Joint programming
• …
Horizon 2020

16. Societal Challenges - ICT
1. Health, demographic change and wellbeing
2. Food security, sustainable agriculture, and forestry, marine,
maritime and inland water research, and the bioeconomy
3. Secure, clean and efficient energy
4. Smart, green and integrated transport
5. Climate action, environment, resource efficiency and raw
materials
6. Europe in a changing world – inclusive, innovative and
reflective societies
7. Secure societies – protecting freedom and security of Europe
and its citizens

17. 1.1 Understanding health, well-being and disease
1.2. Preventing disease
1.3 Treating and managing diseases
1.4 Active ageing and self-management of health
1.5 Methods and data
1.6 Health care provision and integrated care
Horizon 2020 – Societal Challenge 1

18. The silver economy

20. The LINK project

21. The LINK Consortium
Linking Excellence in Biomedical knowledge and Computational
Intelligence Research for personalized management of CVD within PHC
3 partners
3 countries

22. Objectives
 Objective 1: To define a research agenda
 Establishment of a research forum for intelligent algorithms
for PHC in CVD management.
 Industry: Philips, IntelliCare, VTT, Medtronic, TSB
 Academic: California University, Georgia Tech, Uni. Zagreb,
 Professional Societies & Professionals: IFMBE, IEEE-EMBS, European
Cardiology Society, Portuguese Cardiology Society, HL7 Foudation,
ISfTeH, several hospitals
 Decision Makers: Portuguese Health Ministry, Croatian Health
Ministry
 Patients: European Patient Forum, Patients like me
 Contact with fundamental stakeholders in the field to help
identifying key gaps and barriers
 Definition of a research agenda for intelligent algorithms for
PHC in CVD management.

23. Objectives
 Objective 2: To deepen the link between research
institutions in a sustainable way
 Objective 3: To enhance S&T excellence in
intelligent algorithms for PHC for CVD
management
 Objective 4: To increase international impact and
recognition
 Objective 5: To enhance Innovation and Inclusion

24. Research Innovation Forum (RIF)
 Composed by a set of experts from different
countries (US, Italy, Spain, Portugal, Belgium, etc.)
and different profiles (clinician, decision maker,
multinational company, researcher, entrepreneur,
patients ’associations).
 Up to now, 22 members have accepted to be part
of the RIF.

25. Focus
 Analysis of the State of the Art (SoA) and future
trends in pHealth solutions for integrated CVD
management
 Identification of open research problems and
opportunities in algorithms for pHealth solutions
for integrated CVD management to support these
concepts
 Identification of opportunities for Concept
development in pHealth solutions for integrated
CVD management

26. Methodology
 Delphi study - Iterative process
 Statements from internal analysis and discussion with
experts
 3 major focus
 Analysis of the State of the Art (SoA) and future trends in
pHealth solutions for integrated CVD management (13)
 Identification of open research problems and opportunities
in algorithms for pHealth solutions for integrated CVD
management to support these concepts (11)
 Identification of opportunities for Concept development in
pHealth solutions for integrated CVD management (5)

27. Analysis of the SoA and future trends
 3. New algorithms are needed to infer knowledge from
data in order to practice evidence-based medicine (37)
 4. Quality of data is a dimension not to be missed when
researchers are inferring knowledge from heterogeneous
databases (26)
 1. Success of PHC for CVD is fully dependent on data
availability (20)
 7. It is crucial to have real time telemonitoring to provide
PHC services, being possible thanks to mobile services
(16)

28. Analysis of the SoA and future trends
 There a set of statements (2, 6, 10, 11, 12) of interest
for half of the experts. These middle priority
statements are the ones focused on robots, pervasive
telemonitoring, legal issues, ICT based clinical
management and creation of individualized
behavioural models.
 Statements 5 and 13 about data infrastructure and
patient models were the less select/prioritized by
the experts. Statements 8 and 9 about ethical issues
and feature selection were also not selected by the
majority of experts.

29. Identification of open research problems and
opportunities in algorithms for pHealth solutions
TOP PRIORITY QUESTIONS
 11. How to support the integration, discovery and use
of clinical knowledge in daily clinical practice? (27)
 10. How to personalize models for diagnosis and
prognosis? (27)
 5. Which indicators are the key ones for CVD risk
assessment? (26)
 6. What are the best strategies to combine data and
knowledge driven learning and modelling
approaches? (19)

30. Identification of open research problems and
opportunities in algorithms for pHealth solutions
MID PRIORITY QUESTIONS
 1. How can different sources of information be
integrated, especially on large databases? (15)
 8. How can the assessment of cardiovascular
functions and status using wearable technologies
can be improved? (14)
 9. How can multi modal and multi scale data fusion
for robust biosignal processing be improved? (12)
 3. How will mobile technologies improve
continuous monitoring? (10)

31. Opportunities for concept development
of pHealth solutions

32. Brazil and H2020

33. Brazil in H2020
 ALL calls are open to international and more
specifically Brazilian participation. For more details on
funding of applicants from non-EU countries, click
here.
 Key areas of EU-Brazil Cooperation: Sustainable
Agriculture, Bioeconomy, Food security, Nutrition,
Energy, Marine Science, Information and
Communication Technology (ICT), Nanotechnology.

34. Brazil in H2020
 Emerging Economies no longer eligible to
receive automatic funding under H2020
 How can Brazil participate in this framework?
 Coordinated Calls –i.e.– in Biofuels and ICT
 Structuring cofinancing mechanisms to cover the
costs of Brazilian participants within international
consortia together with the EU

35. Brazil in H2020
 In December 2014 CONFAP and the Delegation of
the EU in Brazil sign a “Letter of Intent” to promote
Brazilian participation within Horizon 2020
 Currently almost all State Funding Agencies (FAPs)
in Brazil which are part of CONFAP have signed the
Accession to the Letter of Intent
 Some FAPs have chosen/can choose to sign a
similar letter directly with the EU Delegation

36. Existing local co-funding mechanisms in
Brazil
 Fundação de Amparo à Pesquisa do Estado de São Paulo - FAPESP
 Fundação de Amparo à Pesquisa e Inovação do Estado de Santa
Catarina- FAPESC
 Fundação de Amparo à Pesquisa do Estado de Goiás - FAPEG
 Fundação de Amparo à Pesquisa do Estado de Minas Gerais -
FAPEMIG
 Fundação de amparo à Pesquisa do Distrito Federal - FAPDF
 Fundação Araucária de Apoio ao Desenvolvimento Científico e
Tecnológico do Estado do Paraná – FAPPR
 Fundação de Amparo à Pesquisa e Inovação de Espírito Santo
 Conselho Nacional das Fundações Estaduais de Amparo à Pesquisa
- CONFAP

37. Brazil in H2020
 CONFAP is assisting its FAPs for fine-tuning, finalizing
and launching their own Guidelines which define the
implementation of the Letter of Intent
 What are the Guidelines?
 The Guidelines indicate the operational framework on how
each FAP shall support the participation of its
researchers/participants within projects funded under
Horizon 2020
 In practice, the Guidelines can be considered like a parallel
call for the submission of research and innovation proposals
in coordination with Horizon 2020
 Each FAP shall adjust them to their own needs, funding
capacities, research & innovation priorities, funding
lines

38. Brazil in H2020
 Projects positively evaluated by the FAP shall be
only approved if also approved under H2020
 www.confap.org.br

39. Specific opportunities
 Topic MSCA-ITN-EID European Industrial Doctorates , MSCA-ITN-EJD European
Joint Doctorates , MSCA-ITN-ETN European Training Networks
 Summary: The Innovative Training Networks (ITN) aim to train a new generation
of creative, entrepreneurial and innovative early-stage researchers, able to face
current and future challenges and to convert knowledge and ideas into products
and services for economic and social benefit. ITN will raise excellence and
structure research and doctoral training, extending the traditional academic
research training setting, incorporating the elements of Open Science and
equipping researchers with the right combination of research-related and
transferable competences. It will provide enhanced career perspectives in both
the academic and non-academic sectors through international, interdisciplinary
and intersectoral mobility combined with an innovation-oriented mind-set.
 Deadline 10th January 2017
 URL
https://ec.europa.eu/research/participants/portal/desktop/en/opportunities/h20
20/topics/msca-itn-2017.html
Subprogram MARIE-SKLODOWSKA-CURIE ACTIONS (MSCA)

40. Specific opportunities
 Topic EU-Brazil Joint Call EUB-01-2017 Cloud Computing
 Summary - Cloud computing is now an established global
paradigm for the delivery of IT services in all sectors of the digital
economy. However, further enhancements are still required in
critical aspects of cloud computing, including enhanced security
and privacy; trustworthy clouds; resource pooling; data
management and traceability; virtualization; and hybrid systems.
Support towards intercontinental experimentation on cloud
infrastructures and services are necessary as well, especially in
the context of EU-Brazil cooperation
 Deadline 14 March 2017
 URL
https://ec.europa.eu/research/participants/portal/desktop/en/opp
ortunities/h2020/topics/2079-eub-01-2017.html
Subprogram ICT

41. Specific opportunities
 Topic EU-Brazil Joint Call EUB-02-2017 IoT Pilots
 Summary - In order to make use of the rich potential of the Internet of
Things (IoT) in real-world scenarios, technologies and tools developed
so far need to be demonstrated in controlled environments with the
ultimate goal of validation. Given the specific nature of this Call, widely
replicable pilots are targeted in view of solving specific societal
challenges, in the context of EU-Brazil cooperation.
 Environmental monitoring
 Utilities: smart water management
 Utilities: energy management at home and in buildings52
 Smart assisted living and wellbeing
 Smart manufacturing: customisation
 Deadline 14 March 2017
 URL
http://ec.europa.eu/research/participants/portal4/desktop/en/opportun
ities/h2020/topics/2080-eub-02-2017.html
Subprogram ICT

42. Specific opportunities
 Topic SC1-PM-03-2017 Diagnostic characterisation of rare diseases
 Summary - The aim of this research should be to apply genomics
and/or other –omics and/or other high-throughput approaches for the
molecular characterisation of rare diseases in view of developing
molecular diagnoses for a large number of undiagnosed rare diseases.
Undiagnosed rare diseases may range from a group of unnamed
disorders with common characteristics to a phenotypically well
described disease or group of diseases with an unknown molecular basis.
 The proposal should enable and foster scientific exchange between
stakeholders from countries and regions with different practices and
strategies of rare disease diagnostics.
 Deadline 11 April 2017
 URL
http://ec.europa.eu/research/participants/portal/desktop/en/opportuni
ties/h2020/topics/sc1-pm-03-2017.html
Subprogram HEALTH, DEMOGRAPHIC CHANGE, AND WELL-BEING

43. Specific opportunities
 Topic SC1-PM-15-2017 Personalised coaching for well-being and care
of people as they age
 Summary - This topic aims at developing a proof of concept of radically
new solutions for a personalised "virtual coach", building upon
intelligent ICT environments, access to relevant physiological and
behavioural data, new forms of accessible interaction based on tangible
user interaction concepts, open platforms and emotional computing.
The "coach" should provide personalised advice, guidance and follow-up
for key age related issues in daily life which impact the person's ability to
remain active and independent, for example diet, physical activity, risk
avoidance, preventive measures, lifestyle and activity management,
leisure, social participation and overall wellness.
 Deadline 31 January 2017
 URL
http://ec.europa.eu/research/participants/portal/desktop/en/opportuni
ties/h2020/topics/sc1-pm-15-2017.html
Subprogram HEALTH, DEMOGRAPHIC CHANGE, AND WELL-BEING

44. Specific EU country- Brazil opportunities
 Sweden – VINNOVA
 https://goo.gl/ZKm4qG
 SPAIN (CDTI) – BRAZIL (FINEP)
 Bilateral joint call for proposals to fund R&D in
collaboration between Spanish and Brazilian
companies
 Portugal, Spain, Brazil – IBEROEKA
 CYTED. Instrument to support business technological
cooperation in Latin America

45. Brazil in H2020
 EUROAXESS Brasil is a networking portal that provides
information on funding for researchers in Europe and
Brazil (information only available in English).
 Aporta It is a EU portal with information on national
research and innovation programs in Brazil and helps
find partners for joint projects.
 Ciencias sin fronteras is a financing program for
exchange and international mobility, managed by
CNPq
 CAPES has mobility programs for PhD students and
postdocs with Spain
More information

46. INCOBRA Project
https://www.incobra.eu/
INCOBRA is an EU funded project started on 01/02/2016 aimed at
encouraging bilateral cooperation between R&I actors in Brazil and the
European Union, fostering collaboration and implementing activities
agreed within the BR-EU Policy Dialogue on Science, Technology and
Innovation. Over the next 36 months, various activities will take place to
identify main trends, help with coordination of funding opportunities,
matchmaking of companies and institutions, to network and make
alliances, and to support alignment of EU-BR agendas.

47. Brazil in H2020
 Delegation of the European Union to Brazil:
 http://eeas.europa.eu/delegations/brazil/index_pt.htm
 Questions may be addressed to the Research & Innovation
Section of the EU Delegation to Brazil: DELEGATION-BRAZIL-
CIENCIA@eeas.europa.eu
 The network of National Contact Points (NCPs) is the main
source of guidance, practical information and assistance on all
aspects of participation in Horizon 2020. The list of National
Contact Points can be found in the Participant Portal here.
 The Brazilian NCP Coordinator for Horizon 2020 is:
Prof. Moacyr Martucci Junior
University of São Paulo - Polytechnic School
Avenida Professor Luciano Galberto, travessa 3, 158, Sala C2-49
05508-900, Butanta, Brazil
Tel: +55 11 3091-5626, http://www.pcs.usp.br

48. Resources and useful links
HEIDI – health indicators
http://ec.europa.eu/health/indicators/indicators/index_en.htm
Approved H2020 Workprogramme 2016-17 http://goo.gl/aKh2uG
EIP-AHA website http://ec.europa.eu/research/innovation-
union/index_en.cfm?section=active-healthy-ageing
Scaling up strategy https://goo.gl/ElzbgE
LINK Project https://www.linkresearch.eu/

49. LINK
Linking Excellence in Biomedical knowledge
and Computational Intelligence Research for
personalized management of CVD within PHC
ANALYSIS OF EU – BRAZIL COOPERATION
OPPORTUNITIES ON TELEHEALTH
FOZ DO IGUAÇU, 17TH OCTOBER 2016
Vicente Traver vtraver@itaca.upv.es
Twitter, Skype vtraver
Presentation available at www.slideshare.net/vtraver