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Medication Treatment Failure And Ect
1.
Medication Resistance and
ECT. Is there a problem? by Walter van den Broek
2.
3.
The indication for
ECT has changed: Medication Resistant Depression.
4.
Should you worry
about that?
5.
You’re concerned about
medication resistance and response to ECT p =0.004 p <0.05 Prudic, J et al. Journal of Psychiatric Research 1990
6.
This didn’t help
to resolve your concern Prudic, J. et al. Am J Psychiatry, 1996 ATHF<3, n=18 ATHF 3 or more, n=36 Response 94% 64%
7.
8.
Medication
resistance according to the ATHF does not influence remission and response to subsequent ECT
9.
van den
Broek, et al, Journal of Clin Psychopharmacology 2004
10.
Co variables and
their fate
11.
Characteristics of the
treatment TCA Lithium MAO ECT
12.
Medication resistance with
TCA and lithium does not influence remission and response to subsequent ECT
13.
SSRIs are less
efficacious than TCAs with depressed inpatients
14.
Comparison of imipramine
and lithium addition or fluvoxamine and lithium addition
15.
ECT after Lithium
addition Journal of Clin Psychiatry in press
16.
Others haven’t found
an influence of ATHF medication resistance on response to subsequent ECT
17.
Real World Patients?
18.
Husain et al,
Journal of Affective Disorders, 2004.
19.
CORE
20.
21.
p =0.004 p
<0.05 Prudic, J et al. Journal of Psychiatric Research 1990
22.
Prudic, J. et
al. Am J Psychiatry, 1996 ATHF<3, n=18 ATHF 3 or more, n=36 Response 94% 64%
23.
24.
Answers Anyone?
Hinweis der Redaktion
Dr Walter van den Broek, psychiatrist. Erasmus MC, Rotterdam, The Netherlands. Chair of the committee preparing an update of the Dutch Guidelines for ECT Co-founder and secretary of the Dutch Workgroup for ECT.
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