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What Differs from Theory to 
Practice? 
Emel Eryüksel 
Marmara University, Pulmonary and 
Critical Care
Intrathoracic Pressures and Breathing
Ventilation Strategies 
• Improved safety 
• Improved patient comfort 
• Rapid response to change in patient condition
Ventilation Strategies 
• Improved safety 
• Improved patient comfort 
• Rapid response to change in patient condition
Lung Injury Caused by Forces 
at Low and High Lung Volumes 
n engl j med 369;22
adherence to lung protective 
ventilation?
• -Of the 485 patients, 417 (86%) received 50% or less and 68 (14%) 
received more than 50% of their twice daily ventilator settings adherent 
to lung protective ventilation. A total of 180 (37%) patients never received 
lung protective ventilation during any of their twice daily ventilator 
settings.-
WHY? 
What causes physicians to change 
the way they practice?
Changes in practice are 
sometimes rapid and dramatic. 
laparoscopic cholecystectomy …..
education 
• Why are most physicians not influenced by 
practice guidelines?
scientific knowledge to specific patients
SUMMARIZE THE EVIDENCE 
• To change practice, the evidence must be 
summarized concisely into several key 
interventions….
• For ALI, the evidence supports LPV, which can be defined as 
providing a tidal volume less than or equal to 6 ml/kg of 
predicted body weight and a plateau pressure of less than or 
equal to 30 cm H2O….
IDENTIFY LOCAL BARRIERS TO PRACTICE COMPLIANCE
diagnostic uncertainty
Severity
Patient’s Weight.. 
• 50+ 0.91(centimeters of height-152.4) male 
• 45.5+0.91(centimeters of height-152.4) 
female
ICU TEAM
• Overall, organizational 
barriers and perceived 
barriers related to 
clinician attitudes and 
behaviors were lower 
among physicians 
compared with nurses 
and respiratory 
therapists.
• Physicians specializing in internal medicine 
(including pulmonary/critical care) perceived 
lower barriers and scored higher on the 
Knowledge Test compared with surgery
• Barriers were lower and Knowledge Test 
scores higher among fellows and attending 
physicians vs. interns and residents, who have 
much less experience working in the ICU.
MEASURE PERFORMANCE
• Clinicians can measure performance using 
processes of care (e.g., LPV use), outcomes of 
care (in-hospital mortality)or both.
ENSURE THAT ALL PATIENTS RECEIVE THE THERAPY
Educating clinicians 
• that they are aware of the evidence, agree 
with it, and understand the actions needed to 
comply with the evidence.
Executing
Salon a 13 kasim 15.45 17.00 emel eryüksel-ing

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Salon a 13 kasim 15.45 17.00 emel eryüksel-ing

  • 1. What Differs from Theory to Practice? Emel Eryüksel Marmara University, Pulmonary and Critical Care
  • 3.
  • 4. Ventilation Strategies • Improved safety • Improved patient comfort • Rapid response to change in patient condition
  • 5. Ventilation Strategies • Improved safety • Improved patient comfort • Rapid response to change in patient condition
  • 6. Lung Injury Caused by Forces at Low and High Lung Volumes n engl j med 369;22
  • 7.
  • 8.
  • 9.
  • 10. adherence to lung protective ventilation?
  • 11. • -Of the 485 patients, 417 (86%) received 50% or less and 68 (14%) received more than 50% of their twice daily ventilator settings adherent to lung protective ventilation. A total of 180 (37%) patients never received lung protective ventilation during any of their twice daily ventilator settings.-
  • 12. WHY? What causes physicians to change the way they practice?
  • 13. Changes in practice are sometimes rapid and dramatic. laparoscopic cholecystectomy …..
  • 14. education • Why are most physicians not influenced by practice guidelines?
  • 15.
  • 16. scientific knowledge to specific patients
  • 17. SUMMARIZE THE EVIDENCE • To change practice, the evidence must be summarized concisely into several key interventions….
  • 18. • For ALI, the evidence supports LPV, which can be defined as providing a tidal volume less than or equal to 6 ml/kg of predicted body weight and a plateau pressure of less than or equal to 30 cm H2O….
  • 19. IDENTIFY LOCAL BARRIERS TO PRACTICE COMPLIANCE
  • 21.
  • 23.
  • 24. Patient’s Weight.. • 50+ 0.91(centimeters of height-152.4) male • 45.5+0.91(centimeters of height-152.4) female
  • 25.
  • 27. • Overall, organizational barriers and perceived barriers related to clinician attitudes and behaviors were lower among physicians compared with nurses and respiratory therapists.
  • 28. • Physicians specializing in internal medicine (including pulmonary/critical care) perceived lower barriers and scored higher on the Knowledge Test compared with surgery
  • 29. • Barriers were lower and Knowledge Test scores higher among fellows and attending physicians vs. interns and residents, who have much less experience working in the ICU.
  • 31. • Clinicians can measure performance using processes of care (e.g., LPV use), outcomes of care (in-hospital mortality)or both.
  • 32. ENSURE THAT ALL PATIENTS RECEIVE THE THERAPY
  • 33.
  • 34.
  • 35. Educating clinicians • that they are aware of the evidence, agree with it, and understand the actions needed to comply with the evidence.

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